These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    In a lab filled with curiosities--beakers, microscopes, Bunsen burners, and hundreds upon hundreds of books--sat an investigator who would go on to crack at least two thousand cases in his forty-year career. Known as the "American Sherlock Holmes," Edward Oscar Heinrich was one of America's greatest--and first--forensic scientists, with an uncanny knack for finding clues, establishing evidence, and deducing answers with a skill that seemed almost supernatural.Heinrich was one of the nation's first expert witnesses, working in a time when the turmoil of Prohibition led to sensationalized crime reporting and only a small, systematic study of evidence. However with his brilliance, and commanding presence in both the courtroom and at crime scenes, Heinrich spearheaded the invention of a myriad of new forensic tools that police still use today, including blood spatter analysis, ballistics, lie-detector tests, and the use of fingerprints as courtroom evidence. His work, though not without its serious--some would say fatal--flaws, changed the course of American criminal investigation.Based on years of research and thousands of never-before-published primary source materials, American Sherlock captures the life of the man who pioneered the science our legal system now relies upon--as well as the limits of those techniques and the very human experts who wield them.

    We see it, touch it, and live in it every day. It is a habitat for a mesmerizingly complex world of micro-organisms and physical functions that are vital to our health and our survival. It is also a waste removal plant, a warning system for underlying disease and a dynamic immune barrier to infection. One of the first things people see about us, skin is crucial to our sense of identity, providing us with social significance and psychological meaning. And yet our skin and the fascinating way it functions is largely unknown to us. In prose as lucid as his research underlying it is rigorous, blending in memorable stories from the past and from his own medical experience, Monty Lyman has written a revelatory book exploring our outer surface that will surprise and enlighten in equal measure. Through the lenses of science, sociology, and history--on topics as diverse as the mechanics and magic of touch (how much goes on in the simple act of taking keys out of a pocket and unlocking a door is astounding), the close connection between the skin and the gut, what happens instantly when one gets a paper cut, and how a midnight snack can lead to sunburn--Lyman leads us on a journey across our most underrated and unexplored organ and reveals how our skin is far stranger, more wondrous, and more complex than we have ever imagined.

    Naked power can be grabbed and held temporarily, but it never suffices in the long term. A tyrant who can compel his own people to acclaim him will last longer. The paradox of the modern dictator is that he must create the illusion of popular support. Throughout the twentieth century, hundreds of millions of people were condemned to enthusiasm, obliged to hail their leaders even as they were herded down the road to serfdom.In How to Be a Dictator, Frank Dikötter returns to eight of the most chillingly effective personality cults of the twentieth century. From carefully choreographed parades to the deliberate cultivation of a shroud of mystery through iron censorship, these dictators ceaselessly worked on their own image and encouraged the population at large to glorify them. At a time when democracy is in retreat, are we seeing a revival of the same techniques among some of today’s world leaders?This timely study, told with great narrative verve, examines how a cult takes hold, grows, and sustains itself. It places the cult of personality where it belongs, at the very heart of tyranny.

    Now he offers a framework for envisioning the twenty-first century--an age in which the marriage of human sensitivity and artificial intelligence fundamentally alters and improves the way we live. Kurzweil's prophetic blueprint for the future takes us through the advances that inexorably result in computers exceeding the memory capacity and computational ability of the human brain by the year 2020 (with human-level capabilities not far behind); in relationships with automated personalities who will be our teachers, companions, and lovers; and in information fed straight into our brains along direct neural pathways. Optimistic and challenging, thought-provoking and engaging, The Age of Spiritual Machines is the ultimate guide on our road into the next century.

    While they're at it, they helpfully demystify many complicated things we do know about, from quarks and neutrinos to gravitational waves and exploding black holes. With equal doses of humor and delight, they invite us to see the universe as a vast expanse of mostly uncharted territory that's still ours to explore.This entertaining illustrated science primer is the perfect book for anyone who's curious about all the big questions physicists are still trying to answer.

    Beneath the frozen crusts of several of the small, ice-covered moons of Jupiter and Saturn lurk vast oceans that may have been in existence for as long as Earth, and together may contain more than fifty times its total volume of liquid water. Could there be organisms living in their depths? Alien Oceans reveals the science behind the thrilling quest to find out.Kevin Peter Hand is one of today's leading NASA scientists, and his pioneering research has taken him on expeditions around the world. In this captivating account of scientific discovery, he brings together insights from planetary science, biology, and the adventures of scientists like himself to explain how we know that oceans exist within moons of the outer solar system, like Europa, Titan, and Enceladus. He shows how the exploration of Earth's oceans is informing our understanding of the potential habitability of these icy moons, and draws lessons from what we have learned about the origins of life on our own planet to consider how life could arise on these distant worlds.Alien Oceans describes what lies ahead in our search for life in our solar system and beyond, setting the stage for the transformative discoveries that may await us.

    And it doesn’t exist. Located a mere seventy-five miles outside of Las Vegas in Nevada’s desert, the base has never been acknowledged by the U.S. government-but Area 51 has captivated imaginations for decades.Myths and hypotheses about Area 51 have long abounded, thanks to the intense secrecy enveloping it. Some claim it is home to aliens, underground tunnel systems, and nuclear facilities. Others believe that the lunar landing itself was filmed there. The prevalence of these rumors stems from the fact that no credible insider has ever divulged the truth about his time inside the base. Until now.Annie Jacobsen had exclusive access to nineteen men who served the base proudly and secretly for decades and are now aged 75-92, and unprecedented access to fifty-five additional military and intelligence personnel, scientists, pilots, and engineers linked to the secret base, thirty-two of whom lived and worked there for extended periods. In Area 51, Jacobsen shows us what has really gone on in the Nevada desert, from testing nuclear weapons to building super-secret, supersonic jets to pursuing the War on Terror.This is the first book based on interviews with eye witnesses to Area 51 history, which makes it the seminal work on the subject. Filled with formerly classified information that has never been accurately decoded for the public, Area 51 weaves the mysterious activities of the top-secret base into a gripping narrative, showing that facts are often more fantastic than fiction, especially when the distinction is almost impossible to make.

    It now has 600,000 to a million page hits daily. Every now and then, Munroe would get emails asking him to arbitrate a science debate. 'My friend and I were arguing about what would happen if a bullet got struck by lightning, and we agreed that you should resolve it . . . ' He liked these questions so much that he started up What If. If your cells suddenly lost the power to divide, how long would you survive? How dangerous is it, really, to be in a swimming pool in a thunderstorm? If we hooked turbines to people exercising in gyms, how much power could we produce? What if everyone only had one soulmate?When (if ever) did the sun go down on the British empire? How fast can you hit a speed bump while driving and live?What would happen if the moon went away?In pursuit of answers, Munroe runs computer simulations, pores over stacks of declassified military research memos, solves differential equations, and consults with nuclear reactor operators. His responses are masterpieces of clarity and hilarity, studded with memorable cartoons and infographics. They often predict the complete annihilation of humankind, or at least a really big explosion. Far more than a book for geeks, WHAT IF: Serious Scientific Answers to Absurd Hypothetical Questions explains the laws of science in operation in a way that every intelligent reader will enjoy and feel much the smarter for having read.

    Coffee. Sunscreen. Vapes. George Zaidan reveals what will kill you, what won't, and why--explained with high-octane hilarity, hysterical hijinks, and other things that don't begin with the letter H. INGREDIENTS offers the perspective of a chemist on the stuff we eat, drink, inhale, and smear on ourselves. Apart from the burning question of whether you should eat that Cheeto, Zaidan explores a range of topics. Here's a helpful guide:Stuff in this book: - How bad is processed food? How sure are we?- Is sunscreen safe? Should you use it?- Is coffee good or bad for you?- What's your disease horoscope?- What is that public pool smell made of?- What happens when you overdose on fentanyl in the sun?- What do cassava plants and Soviet spies have in common?- When will you die?Stuff in other books: - Your carbon footprint- Food sustainability- GMOs- CEO pay- Science funding- Politics- Football- Baseball- Any kind of ball reallyZaidan, an MIT-trained chemist who cohosted CNBC's hit Make Me a Millionaire Inventor and wrote and voiced several TED-Ed viral videos, makes chemistry more fun than Hogwarts as he reveals exactly what science can (and can't) tell us about the packaged ingredients sold to us every day. Sugar, spinach, formaldehyde, cyanide, the ingredients of life and death, and how we know if something is good or bad for us--as well as the genius of aphids and their butts--are all discussed in exquisite detail at breakneck speed.

    Sutter emphasizes how amazing it is that we are part of such a huge, complex, and mysterious place. Through metaphors and uncomplicated language, Sutter breathes life into the science of astrophysics, unveiling how particles, forces, and fields interplay to create the greatest of cosmic dramas. Touched with the author's characteristic breezy, conversational style--which has made him a breakout hit on venues such as The Weather Channel, the Science Channel, and his own popular Ask a Spaceman! podcast--he conveys the fun and wonder of delving deeply into the physical processes of the natural universe. He weaves together the past and future histories of our universe with grounded descriptions of essential modern-day physics as well as speculations based on the latest research in cosmology. Topics include our place in the Milky Way galaxy; the cosmic web--a vast web-like pattern in which galaxies are arranged; the origins of our universe in the big bang; the mysteries of dark matter and dark energy; how science has dramatically changed our relationship to the cosmos; conjectures about the future of reality as we know it; and more.For anyone who has ever stared at the starry night sky and wondered how we humans on Earth fit into the big picture, this book is an essential roadmap.

    Illustrating his text with maps, graphics, and photographs, David offers inside information about how the United States, allies and competitors, as well as key private corporations like Moon Express and Jeff Bezos's Blue Origin, plan to reach, inhabit, and even harvest the moon in the decades to come.Spurred on by the Google Lunar XPRIZE--$20 million for the first to get to the moon and send images home--the 21st-century space race back to the moon has become more urgent, and more timely, than ever. Accounts of these new strategies are set against past efforts, including stories never before told about the Apollo missions and Cold War plans for military surveillance and missile launches from the moon. Timely and fascinating, this book sheds new light on our constant lunar companion, offering reasons to gaze up and see it in a different way than ever before.

    In A Generation of Sociopaths, Gibney examines the disastrous policies of the most powerful generation in modern history, showing how the Boomers ruthlessly enriched themselves at the expense of future generations.Acting without empathy, prudence, or respect for facts--acting, in other words, as sociopaths--the Boomers turned American dynamism into stagnation, inequality, and bipartisan fiasco. The Boomers have set a time bomb for the 2030s, when damage to Social Security, public finances, and the environment will become catastrophic and possibly irreversible--and when, not coincidentally, Boomers will be dying off. Gibney argues that younger generations have a fleeting window to hold the Boomers accountable and begin restoring America.

    Kennedy astonished the world on May 25, 1961, when he announced to Congress that the United States should land a man on the Moon by 1970. No group was more surprised than the scientists and engineers at NASA, who suddenly had less than a decade to invent space travel. When Kennedy announced that goal, no one knew how to navigate to the Moon. No one knew how to build a rocket big enough to reach the Moon, or how to build a computer small enough (and powerful enough) to fly a spaceship there. No one knew what the surface of the Moon was like, or what astronauts could eat as they flew there. On the day of Kennedy’s historic speech, America had a total of fifteen minutes of spaceflight experience—with just five of those minutes outside the atmosphere. Russian dogs had more time in space than U.S. astronauts. Over the next decade, more than 400,000 scientists, engineers, and factory workers would send 24 astronauts to the Moon. Each hour of space flight would require one million hours of work back on Earth to get America to the Moon on July 20, 1969. More than fifty years later, One Giant Leap is the sweeping, definitive behind-the-scenes account of the furious race to complete one of mankind’s greatest achievements. It’s a story filled with surprises—from the item the astronauts almost forgot to take with them (the American flag), to the extraordinary impact Apollo would have back on Earth, and on the way we live today. Charles Fishman introduces readers to the men and women who had to solve 10,000 problems before astronauts could reach the Moon. From the research labs of MIT, where the eccentric and legendary pioneer Charles Draper created the tools to fly the Apollo spaceships, to the factories where dozens of women sewed spacesuits, parachutes, and even computer hardware by hand, Fishman captures the exceptional feats of these ordinary Americans. One Giant Leap is the captivating story of men and women charged with changing the world as we knew it—their leaders, their triumphs, their near disasters, all of which led to arguably the greatest success story, and the greatest adventure story, of the twentieth century.

    In this unconventional introduction, physicist Leonard Susskind and hacker-scientist George Hrabovsky offer a first course in physics and associated math for the ardent amateur. Unlike most popular physics books—which give readers a taste of what physicists know but shy away from equations or math—Susskind and Hrabovsky actually teach the skills you need to do physics, beginning with classical mechanics, yourself. Based on Susskind's enormously popular Stanford University-based (and YouTube-featured) continuing-education course, the authors cover the minimum—the theoretical minimum of the title—that readers need to master to study more advanced topics.An alternative to the conventional go-to-college method, The Theoretical Minimum provides a tool kit for amateur scientists to learn physics at their own pace.