Assuming the reader has little prior knowledge of the subject its importance, the principles of the techniques used and their applications are all carefully laid out, with over 250 clearly presented two-colour illustrations. In addition to a number of informative changes to the text throughout the book, the final four chapters have been significantly updated and extended to reflect the striking advances made in recent years in the applications of gene cloning and DNA analysis in biotechnology: Extended chapter on agriculture including new material on glyphosate resistant plantsNew section on the uses of gene cloning and PCR in archaeologyCoverage of ethical concerns relating to pharming, gene therapy and GM crops Gene Cloning and DNA Analysis remains an essential introductory text to a wide range of biological sciences students; including genetics and genomics, molecular biology, biochemistry, immunology and applied biology. It is also a perfect introductory text for any professional needing to learn the basics of the subject. All libraries in universities where medical, life and biological sciences are studied and taught should have copies available on their shelves. View the Gene Cloning and DNA Analysis webpage at www.blackwellpublishing.com/genecloning

    Nature hailed it as a book of grand and daunting sweep.... A splendid and rewarding tour de force. And New Scientist wrote that it captured the essence of modern biology, calling it an extremely significant book which, as a bonus, is very readable. Now, in The Origins of Life, Maynard Smith and Szathmary have completely rewritten Transitions to bring their ideas to a wider audience of general readers. Here is a brilliant, state-of-the-art account of how life evolved on earth, focusing primarily on six major transitions--dramatic breakthroughs in the way that information was passed between generations. The authors offer illuminating explorations of the origin of life itself, the arrival of the first cells with nuclei, the first reproduction by sexual means, the appearance of multicellular plants and animals, the emergence of cooperation and of animal societies, and the birth of language. The Origins of Life represents the thinking of two leading scientists on questions that engage us all--how life began and how it gradually evolved from tiny invisible cells into whales and trees and human beings.

    But if we are supposedly evolution’s greatest creation, why do we have such bad knees? Why do we catch head colds so often—two hundred times more often than a dog does? How come our wrists have so many useless bones? Why is the vast majority of our genetic code pointless? And are we really supposed to swallow and breathe through the same narrow tube? Surely there’s been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last. The human body is one big pile of compromises. But that is also a testament to our greatness: as Lents shows, humans have so many design flaws precisely because we are very, very good at getting around them.   A rollicking, deeply informative tour of humans’ four billion year long evolutionary saga, Human Errors both celebrates our imperfections and offers an unconventional accounting of the cost of our success.

    Lieberman illuminates how these ongoing changes have brought many benefits, but also have created novel conditions to which our bodies are not entirely adapted, resulting in a growing incidence of obesity and new but avoidable diseases, including type-2 diabetes. He proposes that many of these chronic illnesses persist and in some cases are intensifying because of "dysevolution," a pernicious dynamic whereby only the symptoms rather than the causes of these maladies are treated. And finally—provocatively—he advocates the use of evolutionary information to help nudge, push, and sometimes oblige us to create a more salubrious environment.(With charts and line drawings throughout.)From the Hardcover edition.

    

    About The Author: Henry Gray, F.R.S., Fellow of the royal college of Surgeons: Lecturer on anatomy at St. George?s Hospital Medical School. Table Of Contents: Descriptive and Surgical Anatomy The Articulations Muscles and Fasclae The Blood-vascular system The Lymphatics The Nervous system The Organs of special sense The Organs of Digestion The Organs of voice and respiration The urinary organs The Male Organs of Generation The Female Organs of Generation The Surgical Anatomy of Hernia Surgical Anatomy of the Perinaeum General Anatomy or Histology Embryology

    In The Botany of Desire, Michael Pollan ingeniously demonstrates how people and domesticated plants have formed a similarly reciprocal relationship. He masterfully links four fundamental human desires—sweetness, beauty, intoxication, and control—with the plants that satisfy them: the apple, the tulip, marijuana, and the potato. In telling the stories of four familiar species, Pollan illustrates how the plants have evolved to satisfy humankind’s most basic yearnings. And just as we’ve benefited from these plants, we have also done well by them. So who is really domesticating whom?

    In The Violinist's Thumb, he explores the wonders of the magical building block of life: DNA.There are genes to explain crazy cat ladies, why other people have no fingerprints, and why some people survive nuclear bombs. Genes illuminate everything from JFK's bronze skin (it wasn't a tan) to Einstein's genius. They prove that Neanderthals and humans bred thousands of years more recently than any of us would feel comfortable thinking. They can even allow some people, because of the exceptional flexibility of their thumbs and fingers, to become truly singular violinists. Kean's vibrant storytelling makes science entertaining, explaining human history and whimsy while showing how DNA will influence our species' future.

    Colin Tudge argues that we are entering a new phase of biology in which, for the first time, biologists are achieving profound insight into life's true diversity and developing the tools to keep track of it. The Variety of Life heralds this new phase. The first part of the book describes why biologists now feel that there could have been as many as 4,000 billion species on Earth since life began. It then discusses the need for classification, beginning with the most basic principles--the strictly practical classification of fishmongers and foresters, who speak of "shellfish" and differentiate "hardwood" from "softwood"--and moves on to explore the intriguing deliberations of the modern "transformed cladists" and the novel contributions of molecular genetics. Part II describes the creatures themselves. It is divided into 24 sections, each describing a different group, illustrated by nearly 50 double-page spreads which present genealogical "trees" that summarize the evolutionary relationships between the creatures in each group. Some sections describe large, comprehensive groups such as the kingdoms of the Animals or the Plants. Others treat similar sub-groups in more detail, such as the Mammals, a class, or the Hominids, a family. In lively and accessible prose, all the significant groups of creatures--both alive and extinct--are described and their relationships clarified. For general readers and serious biologists alike, The Variety of Life offers an unprecedented storehouse of knowledge of life on earth.

    In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field—the study of life’s diversity and relatedness at the molecular level—is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection—a type of HGT.David Quammen chronicles these discoveries through the lives of the researchers who made them—such as Carl Woese, the most important little-known biologist of the twentieth century; Lynn Margulis, the notorious maverick whose wild ideas about “mosaic” creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health.

    Scott guides readers through the latest advances in stem cell research in clear, accessible language, telling the stories of the researchers who are exploring the potential of stem cells to cure cancer, grow new organs, and repair the immune system. He also leads readers through a discussion of the question at the heart of the explosive ethical debate: How, as a society, do we balance our responsibilities to the unborn and the sick? Stem Cell Now is essential reading for anyone who wants to build an informed opinion on stem cell research.

    He is the founder of Infosys, a global software consulting company which he started with six other professionals and a seed capital of Rs. 10,000 in 1981. Not only did NRNM lead it to become a top ranking Information Technology company in the world, he also showed that it is possible to do business ethically and achieve success without bending any laws or making compromises.This book takes you through the fascinating journey of a seventeen year old who had to sacrifice his entry into the prestigious Indian Institute of Technology because his father did not have money to pay his fees, and who ultimately came up in life to head a global Information Technology company. NRN Murthy had no money, no family backing, but just a quiet gritty determination, and faith in what he believed was the future of business. The one constant factor throughout his life journey has been the adherence to the values he imbibed from his family, which he has personally and professionally lived by-hard work, fairness, decency, honesty, transparency, striving for excellence and belief in meritocracy. It is on the bedrock of these values that Infosys continues to stand firm and prosper despite the fact that NRN stepped down as CEO in 2002.Iconic leader, living legend, one of the greatest entrepreneurs of all time-NRN is all this and more. A man who set new standards of business growth and corporate governance. Written by Ritu Singh, the author of President Pratibha Patil, this book will surely inspire all the readers.

    Obsessive and inspired efforts by scientists to solve mysteries and save lives. From The Hot Zone to The Demon in the Freezer and beyond, Richard Preston’s bestselling works have mesmerized readers everywhere by showing them strange worlds of nature they never dreamed of.Panic in Level 4 is a grand tour through the eerie and unforgettable universe of Richard Preston, filled with incredible characters and mysteries that refuse to leave one’s mind. Here are dramatic true stories from this acclaimed and award-winning author, including:• The phenomenon of “self-cannibals,” who suffer from a rare genetic condition caused by one wrong letter in their DNA that forces them to compulsively chew their own flesh–and why everyone may have a touch of this disease.• The search for the unknown host of Ebola virus, an organism hidden somewhere in African rain forests, where the disease finds its way into the human species, causing outbreaks of unparalleled horror.• The brilliant Russian brothers–“one mathematician divided between two bodies”–who built a supercomputer in their apartment from mail-order parts in an attempt to find hidden order in the number pi (π).In fascinating, intimate, and exhilarating detail, Richard Preston portrays the frightening forces and constructive discoveries that are currently roiling and reordering our world, once again proving himself a master of the nonfiction narrative and, as noted in The Washington Post, “a science writer with an uncommon gift for turning complex biology into riveting page-turners.”From the Hardcover edition.

    MacKinnon realized the grassland he grew up on was not the pristine wilderness he had always believed it to be. Instead, his home prairie was the outcome of a long history of transformation, from the disappearance of the grizzly bear to the introduction of cattle. What remains today is an illusion of the wild--an illusion that has in many ways created our world. In 3 beautifully drawn parts, MacKinnon revisits a globe exuberant with life, where lions roam North America and 20 times more whales swim in the sea. He traces how humans destroyed that reality, out of rapaciousness, yes, but also through a great forgetting. Finally, he calls for an "age of restoration," not only to revisit that richer and more awe-filled world, but to reconnect with our truest human nature. MacKinnon never fails to remind us that nature is a menagerie of marvels. Here are fish that pass down the wisdom of elders, landscapes still shaped by "ecological ghosts," a tortoise that is slowly remaking prehistory. "It remains a beautiful world," MacKinnon writes, "and it is its beauty, not its emptiness, that should inspire us to seek more nature in our lives."

    But in The Music of Life, world renowned physiologist Denis Noble argues that, to truly understand life, we must look beyondthe selfish gene to consider life on a much wider variety of levels. Life, Noble asserts, is a kind of music, a symphonic interplay between genes, cells, organs, body, and environment. He weaves this musical metaphor throughout this personal and deeply lyrical work, illuminating ideas that might otherwise be daunting to non-scientists. In elegant prose, Noblesets out a cutting-edge alternative to the gene's eye view, offering a radical switch of perception in which genes are seen as prisoners and the organism itself is a complex system of many interacting levels. In his more expansive view, life emerges as a process, the ebb and flow of activity in anintricate web of connections. He introduces readers to the realm of systems biology, a field that has been growing in strength in the past decade. Noble, himself one of the founders of this field, argues modern systems biology may be the view we need to adopt to gain a deeper understanding of thenature of life. Drawing on his experiences in his research on the heartbeat, and on evolutionary biology, development, medicine, philosophy, linguistics, and Chinese culture, Noble presents us with a profound and very modern reflection on the nature of life.