Perhaps the most demonized substance in America, scientifically known as Cannabis sativa, simply a very fast growing herb, thrived underground as the nation's most popular illegal drug. Now the tide has shifted: In 1996 California passed the nation's first medical marijuana law, which allowed patients to grow it and use it with a doctor's permission. By 2010, twenty states and the District of Columbia had adopted medical pot laws. In 2012 Colorado and Washington state passed ballot measures legalizing marijuana for adults age 21 and older.The magnitude of the change in America's relationship to marijuana can't be measured in only economic or social terms: There are deeper shifts going on here - cultural realignments, social adjustments, and financial adjustments. The place of marijuana in our lives is being rethought, reconsidered, and recalibrated. Four decades after Richard Nixon declared a War on Drugs, that long campaign has reached a point of exhaustion and failure. The era of its winding down as arrived. Weed the People will take readers a half-step into the future. The issues surrounding the legalization of pot vary from the trivial to the profound. There are new questions of social etiquette: Is one expected to offer a neighborly toke? If so, how? Is it cool to bring cannabis to a Super Bowl party? Yea or nay on the zoning permit for a marijuana shop two doors down from the Safeway? Plus, there are the inevitable conversations between parents and children over exactly what this adult experiment with marijuana means for them.

    To many, continued progress seems certain. But pot was on a similar trajectory forty years ago, only to encounter a fierce backlash. In Grass Roots, historian Emily Dufton tells the remarkable story of marijuana's crooked path from acceptance to demonization and back again, and of the thousands of grassroots activists who made changing marijuana laws their life's work. During the 1970s, pro-pot campaigners with roots in the counterculture secured the drug's decriminalization in a dozen states. Soon, though, concerned parents began to mobilize; finding a champion in Nancy Reagan, they transformed pot into a national scourge and helped to pave the way for an aggressive war on drugs. Chastened marijuana advocates retooled their message, promoting pot as a medical necessity and eventually declaring legalization a matter of racial justice. For the moment, these activists are succeeding -- but marijuana's history suggests how swiftly another counterrevolution could unfold.

    Bell ruling made government sterilization of "undesirable" citizens the law of the land. New York Times bestselling author Adam Cohen tells the story in Imbeciles of one of the darkest moments in the American legal tradition: the Supreme Court's decision to champion eugenic sterilization for the greater good of the country. In 1927, when the nation was caught up in eugenic fervor, the justices allowed Virginia to sterilize Carrie Buck, a perfectly normal young woman, for being an "imbecile." It is a story with many villains, from the superintendent of the Dickensian Virginia Colony for Epileptics and Feebleminded who chose Carrie for sterilization to the former Missouri agriculture professor and Nazi sympathizer who was the nation's leading advocate for eugenic sterilization. But the most troubling actors of all were the eight Supreme Court justices who were in the majority--including William Howard Taft, the former president; Louis Brandeis, the legendary progressive; and Oliver Wendell Holmes, Jr., America's most esteemed justice, who wrote the decision urging the nation to embark on a program of mass eugenic sterilization

    Considering the economic impact of Prohibition—and its repeal—Too High to Fail isn’t a commune-dweller’s utopian rant, it’s an objectively (if humorously) reported account of how one plant can drastically change the shape of our country, culturally, politically, and economically.Too High to Fail covers everything from a brief history of hemp to an insider’s perspective on a growing season in Mendocino County, where cannabis drives 80 percent of the economy (to the tune of $6 billion annually). Investigative journalist Doug Fine follows one plant from seed to patient in the first American county to fully legalize and regulate cannabis farming. He profiles an issue of critical importance to lawmakers, media pundits, and ordinary Americans—whether or not they inhale. It’s a wild ride that includes swooping helicopters, college tuitions paid with cash, cannabis-friendly sheriffs, and never-before-gained access to the world of the emerging legitimate, taxpaying “ganjaprenneur.”

    And as outbreaks of COVID-19, Ebola, MERS, and Zika have demonstrated, we are woefully underprepared to deal with the fallout. So what can -- and must -- we do in order to protect ourselves from mankind's deadliest enemy?Drawing on the latest medical science, case studies, policy research, and hard-earned epidemiological lessons, Deadliest Enemy explores the resources and programs we need to develop if we are to keep ourselves safe from infectious disease. The authors show how we could wake up to a reality in which many antibiotics no longer cure, bioterror is a certainty, and the threat of a disastrous influenza or coronavirus pandemic looms ever larger. Only by understanding the challenges we face can we prevent the unthinkable from becoming the inevitable.Deadliest Enemy is high scientific drama, a chronicle of medical mystery and discovery, a reality check, and a practical plan of action.

    From the blue-blooded pockets of old-WASP New England to the vast tribal lands of the Navajo, Bryan Sykes takes us on a historical genetic tour, interviewing genealogists, geneticists, anthropologists, and everyday Americans with compelling ancestral stories. His findings suggest:• Of Americans whose ancestors came as slaves, virtually all have some European DNA.• Racial intermixing appears least common among descendants of early New England colonists.• There is clear evidence of Jewish genes among descendants of southwestern Spanish Catholics.• Among white Americans, evidence of African DNA is most common in the South.• European genes appeared among Native Americans as early as ten thousand years ago.An unprecedented look into America's genetic mosaic and an impressive contribution to how we perceive race, this is a fascinating book about what it means to be American.

    What is going on? Anatomy of an Epidemic challenges readers to think through that question themselves. First, Whitaker investigates what is known today about the biological causes of mental disorders. Do psychiatric medications fix “chemical imbalances” in the brain, or do they, in fact, create them? Researchers spent decades studying that question, and by the late 1980s, they had their answer. Readers will be startled—and dismayed—to discover what was reported in the scientific journals. Then comes the scientific query at the heart of this book: During the past fifty years, when investigators looked at how psychiatric drugs affected long-term outcomes, what did they find? Did they discover that the drugs help people stay well? Function better? Enjoy good physical health? Or did they find that these medications, for some paradoxical reason, increase the likelihood that people will become chronically ill, less able to function well, more prone to physical illness?  This is the first book to look at the merits of psychiatric medications through the prism of long-term results. Are long-term recovery rates higher for medicated or unmedicated schizophrenia patients? Does taking an antidepressant decrease or increase the risk that a depressed person will become disabled by the disorder? Do bipolar patients fare better today than they did forty years ago, or much worse? When the National Institute of Mental Health (NIMH) studied the long-term outcomes of children with ADHD, did they determine that stimulants provide any benefit?  By the end of this review of the outcomes literature, readers are certain to have a haunting question of their own: Why have the results from these long-term studies—all of which point to the same startling conclusion—been kept from the public?  In this compelling history, Whitaker also tells the personal stories of children and adults swept up in this epidemic. Finally, he reports on innovative programs of psychiatric care in Europe and the United States that are producing good long-term outcomes. Our nation has been hit by an epidemic of disabling mental illness, and yet, as Anatomy of an Epidemic reveals, the medical blueprints for curbing that epidemic have already been drawn up.

    The public has thus been left to wonder whether he is mad, bad, or both.In THE DANGEROUS CASE OF DONALD TRUMP, twenty-seven psychiatrists, psychologists, and other mental health experts argue that, in Mr. Trump’s case, their moral and civic “duty to warn” America supersedes professional neutrality. They then explore Trump’s symptoms and potentially relevant diagnoses to find a complex, if also dangerously mad, man.Philip Zimbardo and Rosemary Sword, for instance, explain Trump’s impulsivity in terms of “unbridled and extreme present hedonism.” Craig Malkin writes on pathological narcissism and politics as a lethal mix. Gail Sheehy, on a lack of trust that exceeds paranoia. Lance Dodes, on sociopathy. Robert Jay Lifton, on the “malignant normality” that can set in everyday life if psychiatrists do not speak up.His madness is catching, too. From the trauma people have experienced under the Trump administration to the cult-like characteristics of his followers, he has created unprecedented mental health consequences across our nation and beyond.It’s not all in our heads. It’s in his."There will not be a book published this fall more urgent, important, or controversial than The Dangerous Case of Donald Trump...profound, illuminating and discomforting" —Bill Moyers

    On the eve of this centenary, journalist Johann Hari set off on an epic three-year, thirty-thousand-mile journey into the war on drugs. What he found is that more and more people all over the world have begun to recognize three startling truths: Drugs are not what we think they are. Addiction is not what we think it is. And the drug war has very different motives to the ones we have seen on our TV screens for so long.In Chasing the Scream, Hari reveals his discoveries entirely through the stories of people across the world whose lives have been transformed by this war. They range from a transsexual crack dealer in Brooklyn searching for her mother, to a teenage hit-man in Mexico searching for a way out. It begins with Hari's discovery that at the birth of the drug war, Billie Holiday was stalked and killed by the man who launched this crusade--and it ends with the story of a brave doctor who has led his country to decriminalize every drug, from cannabis to crack, with remarkable results.Chasing the Scream lays bare what we really have been chasing in our century of drug war--in our hunger for drugs, and in our attempt to destroy them. This book will challenge and change how you think about one of the most controversial--and consequential--questions of our time.

    When a small vial arrives in her mailbox from "Lewis Carroll," Ayelet Waldman is at a low point. Her mood storms have become intolerably severe; she has tried nearly every medication possible; her husband and children are suffering with her. So she opens the vial, places two drops on her tongue, and joins the ranks of an underground but increasingly vocal group of scientists and civilians successfully using therapeutic microdoses of LSD. As Waldman charts her experience over the course of a month--bursts of productivity, sleepless nights, a newfound sense of equanimity--she also explores the history and mythology of LSD, the cutting-edge research into the drug, and the byzantine policies that control it. Drawing on her experience as a federal public defender, and as the mother of teenagers, and her research into the therapeutic value of psychedelics, Waldman has produced a book that is eye-opening, often hilarious, and utterly enthralling.

    In 2017, it claimed nearly fifty thousand lives -- more than gunshots and car crashes combined, and almost as many Americans as were killed in the entire Vietnam War. But even as the overdose crisis ravages our nation -- straining our prison system, dividing families, and defying virtually every legislative solution to treat it-- few understand how it came to be.Opium tells the extraordinary and at times harrowing tale of how we arrived at today's crisis, "mak[ing] timely and startling connections among painkillers, politics, finance, and society" (Laurence Bergreen). The story begins with the discovery of poppy artifacts in ancient Mesopotamia, and goes on to explore how Greek physicians and obscure chemists discovered opium's effects and refined its power, how colonial empires marketed it around the world, and eventually how international drug companies developed a range of powerful synthetic opioids that led to an epidemic of addiction. Throughout, Dr. John Halpern and David Blistein reveal the fascinating role that opium has played in building our modern world, from trade networks to medical protocols to drug enforcement policies. Most importantly, they disentangle how crucial misjudgments, patterns of greed, and racial stereotypes served to transform one of nature's most effective painkillers into a source of unspeakable pain-and how, using the insights of history, state-of-the-art science, and a compassionate approach to the illness of addiction, we can overcome today's overdose epidemic.This urgent and masterfully woven narrative tells an epic story of how one beautiful flower became the fascination of leaders, tycoons, and nations through the centuries and in their hands exposed the fragility of our civilization.

    As she investigates the names and meanings of trees, telling their legends and lore, she reminds us of just how innately bound we are to these protectors of our planet. Since the human race began, we have depended on them for food, shade, shelter and fuel, not to mention furniture, musical instruments, medicine utensils and more. Wells has a remarkable ability to dig up the curious and the captivating: At one time, a worm found in a hazelnut prognosticated ill fortune. Rowan trees were planted in churchyards to prevent the dead from rising from their graves. Greek arrows were soaked in deadly yew, and Shakespeare’s witches in Macbeth used “Gall of goat and slips of Yew” to make their lethal brew. One bristlecone pine, at about 4,700 years old, is thought to be the oldest living plant on earth. All this and more can be found in the beautifully illustrated pages (themselves born of birch bark!) of 100 Trees.

    Applying the same objective criteria to legal and illegal substances, an argument is made that legality is not a clear measure for harm. Tackling a variety of questions, such as Which is more harmful—Ecstasy or alcohol? Can addiction be cured? and Does the "War on Drugs" have serious unintended effects that can hurt children?, this analysis equips readers with the ability to make educated decisions regarding drugs both personally and in their communities. Broadening the scope of the discussion, a framework is explored for formulating national drug policies that will minimize a myriad of harms—social, medical, criminal, financial, and environmental.

    And liberated from its mathematical underpinnings, physics suddenly becomes accessible to anyone with the curiosity and imagination to explore its beauty. Science without math? It's not that unusual. For example, we can understand the concept of gravity without solving a single equation. So for all those who may have pondered what makes blueberries blue and strawberries red; for those who have wondered if sound really travels in waves; and why light behaves so differently from any other phenomenon in the universe, it's all a matter of quantum physics. Absolutely Small presents (and demystifies) the world of quantum science like no book before. It explores scientific concepts--from particles of light, to probability, to states of matter, to what makes greenhouse gases bad--in considerable depth, but using examples from the everyday world. Challenging without being intimidating, accessible but not condescending, Absolutely Small develops the reader's intuition for the very nature of things at their most basic and intriguing levels.

    In the era of Donald Trump, many lower- and middle-class white Americans are drawn to politicians who pledge to make their lives great again. But as Dying of Whiteness shows, the policies that result actually place white Americans at ever-greater risk of sickness and death.Physician Jonathan M. Metzl's quest to understand the health implications of "backlash governance" leads him across America's heartland. Interviewing a range of everyday Americans, he examines how racial resentment has fueled pro-gun laws in Missouri, resistance to the Affordable Care Act in Tennessee, and cuts to schools and social services in Kansas. And he shows these policies' costs: increasing deaths by gun suicide, rising dropout rates, and falling life expectancies. White Americans, Metzl argues, must reject the racial hierarchies that promise to aid them but in fact lead our nation to demise.