Torn from their homes and families, these men, women, and children were loaded into shipboard cattle stalls and abandoned in a lawless place where brutality held sway. Many did not have leprosy, and many who did were not contagious, yet all were ensnared in a shared nightmare. Here, for the first time, John Tayman reveals the complete history of the Molokai settlement and its unforgettable inhabitants. It's an epic of ruthless manhunts, thrilling escapes, bizarre medical experiments, and tragic, irreversible error. Carefully researched and masterfully told, The Colony is a searing tale of individual bravery and extraordinary survival, and stands as a testament to the power of faith, compassion, and the human spirit.

    The most fatal virus known to science, rabies — a disease that spreads avidly from animals to humans — kills nearly one hundred percent of its victims once the infection takes root in the brain. In this critically acclaimed exploration, journalist Bill Wasik and veterinarian Monica Murphy chart four thousand years of the history, science, and cultural mythology of rabies. From Greek myths to zombie flicks, from the laboratory heroics of Louis Pasteur to the contemporary search for a lifesaving treatment, Rabid is a fresh and often wildly entertaining look at one of humankind’s oldest and most fearsome foes.

      In 1875, tuberculosis was the deadliest disease in the world, accountable for a third of all deaths. A diagnosis of TB—often called consumption—was a death sentence. Then, in a triumph of medical science, a German doctor named Robert Koch deployed an unprecedented scientific rigor to discover the bacteria that caused TB. Koch soon embarked on a remedy—a remedy that would be his undoing.   When Koch announced his cure for consumption, Arthur Conan Doyle, then a small-town doctor in England and sometime writer, went to Berlin to cover the event. Touring the ward of reportedly cured patients, he was horrified. Koch’s "remedy" was either sloppy science or outright fraud.   But to a world desperate for relief, Koch’s remedy wasn’t so easily dismissed. As Europe’s consumptives descended upon Berlin, Koch urgently tried to prove his case. Conan Doyle, meanwhile, returned to England determined to abandon medicine in favor of writing. In particular, he turned to a character inspired by the very scientific methods that Koch had formulated: Sherlock Holmes.   Capturing the moment when mystery and magic began to yield to science, The Remedy chronicles the stunning story of how the germ theory of disease became a true fact, how two men of ambition were emboldened to reach for something more, and how scientific discoveries evolve into social truths.

    With a tremendous cracking and splintering of oak, it struck the ship just beneath the anchor secured at the cat-head on the port bow..." In the Heart of the Sea brings to new life the incredible story of the wreck of the whaleship Essex - an event as mythic in its own century as the Titanic disaster in ours, and the inspiration for the climax of Moby-Dick. In a harrowing page-turner, Nathaniel Philbrick restores this epic story to its rightful place in American history.In 1820, the 240-ton Essex set sail from Nantucket on a routine voyage for whales. Fifteen months later, in the farthest reaches of the South Pacific, it was repeatedly rammed and sunk by an eighty-ton bull sperm whale. Its twenty-man crew, fearing cannibals on the islands to the west, made for the 3,000-mile-distant coast of South America in three tiny boats. During ninety days at sea under horrendous conditions, the survivors clung to life as one by one, they succumbed to hunger, thirst, disease, and fear.Philbrick interweaves his account of this extraordinary ordeal of ordinary men with a wealth of whale lore and with a brilliantly detailed portrait of the lost, unique community of Nantucket whalers. Impeccably researched and beautifully told, the book delivers the ultimate portrait of man against nature, drawing on a remarkable range of archival and modern sources, including a long-lost account by the ship's cabin boy.At once a literary companion and a page-turner that speaks to the same issues of class, race, and man's relationship to nature that permeate the works of Melville, In the Heart of the Sea will endure as a vital work of American history.

    If such a plague returned today, taking a comparable percentage of the U.S. population with it, 1.5 million Americans would die.The fascinating, true story of the world's deadliest disease.In 1918, the Great Flu Epidemic felled the young and healthy virtually overnight. An estimated forty million people died as the epidemic raged. Children were left orphaned and families were devastated. As many American soldiers were killed by the 1918 flu as were killed in battle during World War I. And no area of the globe was safe. Eskimos living in remote outposts in the frozen tundra were sickened and killed by the flu in such numbers that entire villages were wiped out.Scientists have recently rediscovered shards of the flu virus frozen in Alaska and preserved in scraps of tissue in a government warehouse. Gina Kolata, an acclaimed reporter for "The New York Times," unravels the mystery of this lethal virus with the high drama of a great adventure story. Delving into the history of the flu and previous epidemics, detailing the science and the latest understanding of this mortal disease, Kolata addresses the prospects for a great epidemic recurring, and, most important, what can be done to prevent it.

    Heading deep into uncharted Arctic waters, they carried the aspirations of a young country burning to be the first nation to reach the North Pole. Two years into the voyage, the Jeannette's hull was breached by an impassable stretch of pack ice, forcing the crew to abandon ship amid torrents of rushing of water. Hours later, the ship had sunk below the surface, marooning the men a thousand miles north of Siberia, where they faced a terrifying march with minimal supplies across the endless ice pack.Enduring everything from snow blindness and polar bears to ferocious storms and labyrinths of ice, the crew battled madness and starvation as they struggled desperately to survive. With thrilling twists and turns, In The Kingdom of Ice is a tale of heroism and determination in the most brutal place on Earth.

    In The Demon in the Freezer, his first nonfiction book since The Hot Zone, a #1 New York Times bestseller, Richard Preston takes us into the heart of Usamriid, the United States Army Medical Research Institute of Infectious Diseases at Fort Detrick, Maryland, once the headquarters of the U.S. biological weapons program and now the epicenter of national biodefense.Peter Jahrling, the top scientist at Usamriid, a wry virologist who cut his teeth on Ebola, one of the world’s most lethal emerging viruses, has ORCON security clearance that gives him access to top secret information on bioweapons. His most urgent priority is to develop a drug that will take on smallpox-and win. Eradicated from the planet in 1979 in one of the great triumphs of modern science, the smallpox virus now resides, officially, in only two high-security freezers-at the Centers for Disease Control in Atlanta and in Siberia, at a Russian virology institute called Vector. But the demon in the freezer has been set loose. It is almost certain that illegal stocks are in the possession of hostile states, including Iraq and North Korea. Jahrling is haunted by the thought that biologists in secret labs are using genetic engineering to create a new superpox virus, a smallpox resistant to all vaccines.Usamriid went into a state of Delta Alert on September 11 and activated its emergency response teams when the first anthrax letters were opened in New York and Washington, D.C. Preston reports, in unprecedented detail, on the government’s response to the attacks and takes us into the ongoing FBI investigation. His story is based on interviews with top-level FBI agents and with Dr. Steven Hatfill.Jahrling is leading a team of scientists doing controversial experiments with live smallpox virus at CDC. Preston takes us into the lab where Jahrling is reawakening smallpox and explains, with cool and devastating precision, what may be at stake if his last bold experiment fails.

    After months of grueling travel, the 81 men, women and children would be trapped for a brutal winter with little food and only primitive shelter. The conclusion is known: by spring of the next year, the Donner Party was synonymous with the most harrowing extremes of human survival. But until now, the full story of what happened, what it tells us about human nature and about America's westward expansion, remained shrouded in myth.Drawing on fresh archaeological evidence, recent research on topics ranging from survival rates to snowfall totals, and heartbreaking letters and diaries made public by descendants a century-and-a-half after the tragedy, Ethan Rarick offers an intimate portrait of the Donner party and their unimaginable ordeal: a mother who must divide her family, a little girl who shines with courage, a devoted wife who refuses to abandon her husband, a man who risks his life merely to keep his word. But Rarick resists both the gruesomely sensationalist accounts of the Donner party as well as later attempts to turn the survivors into archetypal pioneer heroes. The Donner Party, Rarick writes, is a story of hard decisions that were neither heroic nor villainous. Often, the emigrants displayed a more realistic and typically human mixture of generosity and selfishness, an alloy born of necessity.A fast-paced, heart-wrenching, clear-eyed narrative history, A Desperate Hope casts new light on one of America's most horrific encounters between the dream of a better life and the harsh realities such dreams so often must confront.

    Mowat's account of the summer he lived in the frozen tundra alone—studying the wolf population and developing a deep affection for the wolves (who were of no threat to caribou or man)—is today celebrated as a classic of nature writing, at once a tale of remarkable adventures and indelible record of myths and magic of wolves.

    In the midst of all this death, a bizarre disease appeared in Europe. Eventually known as encephalitis lethargica, or sleeping sickness, it would spread across the world, leaving millions dead or locked in institutions. Then, in 1927, it would disappear as suddenly as it had arrived-or so the doctors at first thought. Asleep, set in 1920s and '30s New York, follows a group of neurologists through hospitals and insane asylums as they try to solve this worldwide epidemic. The symptoms could include not only unending sleep but dangerous insomnia, facial tics, catatonia, Parkinson's, and even violent insanity. Molly Caldwell Crosby, acclaimed author of The American Plague, explores the frightening history of this forgotten disease- and details the frantic effort to conquer it before it strikes again.

    Drawing on newly available papers of Jonas Salk, Albert Sabin and other key players, Oshinsky paints a suspenseful portrait of the race for the cure, weaving a dramatic tale centered on the furious rivalry between Salk and Sabin. He also tells the story of Isabel Morgan, perhaps the most talented of all polio researchers, who might have beaten Salk to the prize if she had not retired to raise a family.Oshinsky offers an insightful look at the National Foundation for Infantile Paralysis, which was founded in the 1930s by FDR and Basil O'Connor, it revolutionized fundraising and the perception of disease in America. Oshinsky also shows how the polio experience revolutionized the way in which the government licensed and tested new drugs before allowing them on the market, and the way in which the legal system dealt with manufacturers' liability for unsafe products. Finally, and perhaps most tellingly, Oshinsky reveals that polio was never the raging epidemic portrayed by the media, but in truth a relatively uncommon disease. But in baby-booming America--increasingly suburban, family-oriented, and hygiene-obsessed--the specter of polio, like the specter of the atomic bomb, soon became a cloud of terror over daily life.Both a gripping scientific suspense story and a provocative social and cultural history, Polio opens a fresh window onto postwar America.

    For seventeen days, he and his team of dogs endured blinding wind, snowstorms, frostbite, dogfights, moose attacks, sleeplessness, hallucinations--and the relentless push to go on. Winterdance is the enthralling account of a stunning wilderness journey of discovery and transformation (Chicago Tribune), lived and told by the best author of man-against-nature adventures writing today (Publishers Weekly).

    Thus began the legendary ordeal of Shackleton and his crew of twenty-seven men. When their ship was finally crushed between two ice floes, they attempted a near-impossible journey over 850 miles of the South Atlantic's heaviest seas to the closest outpost of civilization.In Endurance, the definitive account of Ernest Shackleton's fateful trip, Alfred Lansing brilliantly narrates the harrowing and miraculous voyage that has defined heroism for the modern age.

    After barely surviving the agony of smallpox themselves, they flouted eighteenth-century medicine by borrowing folk knowledge from African slaves and Eastern women in frantic bids to protect their children. From their heroic struggles stems the modern science of immunology as well as the vaccinations that remain our only hope should the disease ever be unleashed again.Jennifer Lee Carrell transports readers back to the early eighteenth century to tell the tales of Lady Mary Wortley Montagu and Dr. Zabdiel Boylston, two iconoclastic figures who helped save London and Boston from the deadliest disease mankind has known.

    It killed more people in twenty-four months than AIDS killed in twenty-four years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision of science and epidemic disease. Magisterial in its breadth of perspective and depth of research and now revised to reflect the growing danger of the avian flu, The Great Influenza is ultimately a tale of triumph amid tragedy, which provides us with a precise and sobering model as we confront the epidemics looming on our own horizon. John M. Barry has written a new afterword for this edition that brings us up to speed on the terrible threat of the avian flu and suggest ways in which we might head off another flu pandemic.