Francis Collins, director of the National Institute of Health, 2007 recipient of the Presidential Medal of Freedom, and 15-year head of the Human Genome Project, comes one of the most important medical books of the year: The Language of Life. With accessible, insightful prose, Dr. Collins describes the medical, scientific, and genetic revolution that is currently unlocking the secrets of “personalized medicine,” and offers practical advice on how to utilize these discoveries for you and your family’s current and future health and well-being. In the words of Dr. Jerome Groopman (How Doctors Think), The Language of Life “sets out hope without hype, and will enrich the mind and uplift the heart.”

    This brilliant work heralds the new age of nanotechnology, which will give us thorough and inexpensive control of the structure of matter.  Drexler examines the enormous implications of these developments for medicine, the economy, and the environment, and makes astounding yet well-founded projections for the future.

    We often overlook the historical link between mathematics and technological advances, says Stewart—but this connection is integral to any complete understanding of human history.Equations are modeled on the patterns we find in the world around us, says Stewart, and it is through equations that we are able to make sense of, and in turn influence, our world. Stewart locates the origins of each equation he presents—from Pythagoras's Theorem to Newton's Law of Gravity to Einstein's Theory of Relativity—within a particular historical moment, elucidating the development of mathematical and philosophical thought necessary for each equation's discovery. None of these equations emerged in a vacuum, Stewart shows; each drew, in some way, on past equations and the thinking of the day. In turn, all of these equations paved the way for major developments in mathematics, science, philosophy, and technology. Without logarithms (invented in the early 17th century by John Napier and improved by Henry Briggs), scientists would not have been able to calculate the movement of the planets, and mathematicians would not have been able to develop fractal geometry. The Wave Equation is one of the most important equations in physics, and is crucial for engineers studying the vibrations in vehicles and the response of buildings to earthquakes. And the equation at the heart of Information Theory, devised by Claude Shannon, is the basis of digital communication today.An approachable and informative guide to the equations upon which nearly every aspect of scientific and mathematical understanding depends, In Pursuit of the Unknown is also a reminder that equations have profoundly influenced our thinking and continue to make possible many of the advances that we take for granted.

    This clear, concise look at the basic principles and concepts of genetics uses a human genetics perspective to discuss the methods and experiments upon which genetic principles are based, such as DNA replication.

    In this collection of landmark mathematical works, editor Stephen Hawking has assembled the greatest feats humans have ever accomplished using just numbers and their brains.

    Since then, we have sequenced the full genomes of a number of mankind's primate relatives at a remarkable rate. The genomes of the common chimpanzee(2005) and bonobo (2012), orangutan (2011), gorilla (2012), and macaque monkey (2007) have already been identified, and the determination of other primate genomes is well underway. Researchers are beginning to unravel our full genomic history, comparing it with closely related species to answerage-old questions about how and when we evolved. For the first time, we are finding our own ancestors in our genome and are thereby gleaning new information about our evolutionary past.In Ancestors in Our Genome, molecular anthropologist Eugene E. Harris presents us with a complete and up-to-date account of the evolution of the human genome and our species. Written from the perspective of population genetics, and in simple terms, the book traces human origins back to their sourceamong our earliest human ancestors, and explains many of the most intriguing questions that genome scientists are currently working to answer. For example, what does the high level of discordance among the gene trees of humans and the African great apes tell us about our respective separations fromour common ancestor? Was our separation from the apes fast or slow, and when and why did it occur? Where, when, and how did our modern species evolve? How do we search across genomes to find the genomic underpinnings of our large and complex brains and language abilities? How can we find the genomicbases for life at high altitudes, for lactose tolerance, resistance to disease, and for our different skin pigmentations? How and when did we interbreed with Neandertals and the recently discovered ancient Denisovans of Asia? Harris draws upon extensive experience researching primate evolution inorder to deliver a lively and thorough history of human evolution. Ancestors in Our Genome is the most complete discussion of our current understanding of the human genome available.

    Called the Pope by his peers, he was regarded as infallible in his instincts and research. His discoveries changed our world; they led to weapons of mass destruction and conversely to life-saving medical interventions.This unassuming man struggled with issues relevant today, such as the threat of nuclear annihilation and the relationship of science to politics. Fleeing Fascism and anti-Semitism, Fermi became a leading figure in America's most secret project: building the atomic bomb. The last physicist who mastered all branches of the discipline, Fermi was a rare mixture of theorist and experimentalist. His rich legacy encompasses key advances in fields as diverse as comic rays, nuclear technology, and early computers.In their revealing book, The Pope of Physics, Gino Segré and Bettina Hoerlin bring this scientific visionary to life. An examination of the human dramas that touched Fermi’s life as well as a thrilling history of scientific innovation in the twentieth century, this is the comprehensive biography that Fermi deserves.

    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    But the president insisted there was nothing to worry about.Fortunately, we are still a nation of skeptics. Fortunately, there are those among us who study pandemics and are willing to look unflinchingly at worst-case scenarios. Michael Lewis’s taut and brilliant nonfiction thriller pits a band of medical visionaries against the wall of ignorance that was the official response of the Trump administration to the outbreak of COVID-19.The characters you will meet in these pages are as fascinating as they are unexpected. A thirteen-year-old girl’s science project on transmission of an airborne pathogen develops into a very grown-up model of disease control. A local public-health officer uses her worm’s-eye view to see what the CDC misses, and reveals great truths about American society. A secret team of dissenting doctors, nicknamed the Wolverines, has everything necessary to fight the pandemic: brilliant backgrounds, world-class labs, prior experience with the pandemic scares of bird flu and swine flu…everything, that is, except official permission to implement their work.Michael Lewis is not shy about calling these people heroes for their refusal to follow directives that they know to be based on misinformation and bad science. Even the internet, as crucial as it is to their exchange of ideas, poses a risk to them. They never know for sure who else might be listening in.

    This remarkable book describes Fout's odyssey from novice researcher to celebrity scientist to impassioned crusader for the rights of animals. Living and conversing with these sensitive creatures has given him a profound appreciation of what they can teach us about ourselves. It has also made Fouts an outspoken opponent of biomedical experimentation on chimpanzees. A voyage of scientific discovery and interspecies communication, this is a stirring tale of friendship, courage, and compassion that will change forever the way we view our biological--and spritual--next of kin. Fouts is a professor of Psychology.

    In a "witty, erudite, and entertaining" (Esquire) style, Simon Garfield explains how the experimental mishap that produced an odd shade of purple revolutionized fashion, as well as industrial applications of chemistry research. Occasionally honored in certain colleges and chemistry clubs, Perkin until now has been a forgotten man.

    Science has seen its fair share of punch-ups over the years, but one debate, in the field of biology, has become notorious for its intensity. Over the last twenty years, Richard Dawkins and Stephen Jay Gould have engaged in a savage battle over evolution, which continues to rage even after Gould's death in 2002. Kim Sterelny moves beyond caricature to expose the real differences between the conceptions of evolution of these two leading scientists. He shows that the conflict extends beyond evolution to their very beliefs in science itself; and, in Gould?s case, to domains in which science plays no role at all.

    Humans have "subdued 75 per cent of the land surface, concocted a wizardry of industrial and medical marvels, strung lights all across the darkness." We now collect the DNA of vanishing species in a "frozen ark," equip orangutans with iPads, create wearable technologies and synthetic species that might one day outsmart us. With her distinctive gift for making scientific discovery intelligible to the layperson, Ackerman takes us on an exciting journey to understand this bewildering new reality, introducing us to many of the people and ideas now creating--perhaps saving--the future.The Human Ageis a surprising, optimistic engagement with the dramatic transformations that have shaped, and continue to alter, our world, our relationship with nature and our prospects for the future.

    Silver takes a cautiously optimistic look at the scientific advances that will allow us to engineer life in ways that were unimaginable just a few short years ago—indeed, in ways that go far beyond cloning. In clear, engaging, and accessible prose, Silver demystifies the science behind a myriad of thrilling and frightening new possibilities, in a book that is essential reading for anyone who wants to understand the hopes and dilemmas of the American family in the twenty-first century.

    Fukuyama sketches a brief history of man's changing understanding of human nature: from Plato and Aristotle to the modernity's utopians and dictators who sought to remake mankind for ideological ends. Fukuyama argues that the ability to manipulate the DNA of all of one person's descendants will have profound, and potentially terrible, consequences for our political order, even if undertaken with the best of intentions. In Our Posthuman Future, one of our greatest social philosophers begins to describe the potential effects of genetic exploration on the foundation of liberal democracy: the belief that human beings are equal by nature.