S. Ramachandran is at the forefront of his field-so much so that Richard Dawkins dubbed him the "Marco Polo of neuroscience." Now, in a major new work, Ramachandran sets his sights on the mystery of human uniqueness. Taking us to the frontiers of neurology, he reveals what baffling and extreme case studies can teach us about normal brain function and how it evolved. Synesthesia becomes a window into the brain mechanisms that make some of us more creative than others. And autism--for which Ramachandran opens a new direction for treatment--gives us a glimpse of the aspect of being human that we understand least: self-awareness. Ramachandran tackles the most exciting and controversial topics in neurology with a storyteller's eye for compelling case studies and a researcher's flair for new approaches to age-old questions. Tracing the strange links between neurology and behavior, this book unveils a wealth of clues into the deepest mysteries of the human brain.

    Radiation: What could go wrong? In short, plenty. From Marie Curie carrying around a vial of radium salt because she liked the pretty blue glow to the large-scale disasters at Chernobyl and Fukushima, dating back to the late nineteenth century, nuclear science has had a rich history of innovative exploration and discovery, coupled with mistakes, accidents, and downright disasters. In this lively book, long-time advocate of continued nuclear research and nuclear energy James Mahaffey looks at each incident in turn and analyzes what happened and why, often discovering where scientists went wrong when analyzing past meltdowns. Every incident, while taking its toll, has led to new understanding of the mighty atom—and the fascinating frontier of science that still holds both incredible risk and great promise.

    But over the past decade, a wave of dramatic findings in the cutting-edge science of endurance has completely overturned our understanding of human limitation. Endure widely disseminates these findings for the first time: It’s the brain that dictates how far we can go—which means we can always push ourselves further.Hutchinson presents an overview of science’s search for understanding human fatigue, from crude experiments with electricity and frogs’ legs to sophisticated brain imaging technology. Going beyond the traditional mechanical view of human limits (like a car with a brick on its gas pedal, we go until the tank runs out of gas), he instead argues that a key element in endurance is how the brain responds to distress signals—whether heat, or cold, or muscles screaming with lactic acid—and reveals that we can train to improve brain response.An elite distance runner himself, Hutchinson takes us to the forefront of the new sports psychology—brain electrode jolts, computer-based training, subliminal messaging—and presents startling new discoveries enhancing the performance of athletes today and shows how anyone can utilize these tactics to bolster their own performance—and get the most out of their bodies.

    Recent progress in genetic manipulations and calorie-restricted diets in laboratory animals hold forth the promise that someday science will enable us to exert total control over our own biological aging.Nearly all scientists who study the biology of aging agree that we will someday be able to substantially slow down the aging process, extending our productive, youthful lives. Dr. Aubrey de Grey is perhaps the most bullish of all such researchers. As has been reported in media outlets ranging from 60 Minutes to The New York Times, Dr. de Grey believes that the key biomedical technology required to eliminate aging-derived debilitation and death entirely--technology that would not only slow but periodically reverse age-related physiological decay, leaving us biologically young into an indefinite future--is now within reach.In Ending Aging, Dr. de Grey and his research assistant Michael Rae describe the details of this biotechnology. They explain that the aging of the human body, just like the aging of man-made machines, results from an accumulation of various types of damage.  As with man-made machines, this damage can periodically be repaired, leading to indefinite extension of the machine's fully functional lifetime, just as is routinely done with classic cars.  We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that damage.  By demystifying aging and its postponement for the nonspecialist reader, de Grey and Rae systematically dismantle the fatalist presumption that aging will forever defeat the efforts of medical science.

    Frizzle were a physics student of Stephen Hawking, she might have written THE UNIVERSE IN YOUR HAND, a wild tour through the reaches of time and space, from the interior of a proton to the Big Bang to the rough suburbs of a black hole. It's friendly, excitable, erudite, and cosmic."—Jordan Ellenberg, New York Times besteselling author of How Not To Be WrongQuantum physics, black holes, string theory, the Big Bang, dark matter, dark energy, parallel universes: even if we are interested in these fundamental concepts of our world, their language is the language of math. Which means that despite our best intentions of finally grasping, say, Einstein's Theory of General Relativity, most of us are quickly brought up short by a snarl of nasty equations or an incomprehensible graph.Christophe Galfard's mission in life is to spread modern scientific ideas to the general public in entertaining ways. Using his considerable skills as a brilliant theoretical physicist and successful young adult author, The Universe in Your Hand employs the immediacy of simple, direct language to show us, not explain to us, the theories that underpin everything we know about our universe. To understand what happens to a dying star, we are asked to picture ourselves floating in space in front of it. To get acquainted with the quantum world, we are shrunk to the size of an atom and then taken on a journey. Employing everyday similes and metaphors, addressing the reader directly, and writing stories rather than equations renders these astoundingly complex ideas in an immediate and visceral way.Utterly captivating and entirely unique, The Universe in Your Hand will find its place among other classics in the field.

    In The Life of the Cosmos, Smolin cuts the Gordian knot of cosmology with a simple, powerful idea: "The underlying structure of our world, " he writes, "is to be found in the logic of evolution." Today's physicists have overturned Newton's view of the universe, yet they continue to cling to an understanding of reality not unlike Newton's own - as a clock, an intricate mechanism, governed by laws which are mathematical and eternally true. Smolin argues that the laws of nature we observe may be in part the result of a process of natural selection which took place before the big bang. Smolin's ideas are based on recent developments in cosmology, quantum theory, relativity and string theory, yet they offer, at the same time, an unprecedented view of how these developments may fit together to form a new theory of cosmology. From this perspective, the lines between the simple and the complex, the fundamental and the emergent, and even between the biological and the physical are redrawn. The result is a framework that illuminates many intractable problems, from the paradoxes of quantum theory and the nature of space and time to the problem of constructing a final theory of physics. As he argues for this new view, Smolin introduces the reader to recent developments in a wide range of fields, from string theory and quantum gravity to evolutionary theory the structure of galaxies. He examines the philosophical roots of controversies in the foundations of physics, and shows how they may be transformed as science moves towardunderstanding the universe as an interrelated, self-constructed entity, within which life and complexity have a natural place, and in which "the occurrence of novelty, indeed the perpetual birth of novelty, can be understood."

    While some books explore our genetic inheritance and popular television shows celebrate ancestry, this is the first book to explore how everything from DNA to emotions to names and the stories that form our lives are all part of our human legacy. This book shows how trust is inherited in Africa, silence is passed down in Tasmania, and how the history of nations is written in our DNA. From fateful, ancient encounters to modern mass migrations and medical diagnoses, Kenneally explains how the forces that shaped the history of the world ultimately shape each human who inhabits it. The Invisible History of the Human Race is a deeply researched, carefully crafted, and provocative perspective on how our stories, psychology, and genetics affect our past and our future.

    Now comes a gripping account of the doctors and scientists fighting to protect us, an urgent wake-up call about the future of emerging viruses—from the #1 bestselling author of The Hot Zone, soon to be a National Geographic original miniseries.This time, Ebola started with a two-year-old child who likely had contact with a wild creature and whose entire family quickly fell ill and died. The ensuing global drama activated health professionals in North America, Europe, and Africa in a desperate race against time to contain the viral wildfire. By the end—as the virus mutated into its deadliest form, and spread farther and faster than ever before—30,000 people would be infected, and the dead would be spread across eight countries on three continents.In this taut and suspenseful medical drama, Richard Preston deeply chronicles the outbreak, in which we saw for the first time the specter of Ebola jumping continents, crossing the Atlantic, and infecting people in America. Rich in characters and conflict—physical, emotional, and ethical—Crisis in the Red Zone is an immersion in one of the great public health calamities of our time.Preston writes of doctors and nurses in the field putting their own lives on the line, of government bureaucrats and NGO administrators moving, often fitfully, to try to contain the outbreak, and of pharmaceutical companies racing to develop drugs to combat the virus. He also explores the charged ethical dilemma over who should and did receive the rare doses of an experimental treatment when they became available at the peak of the disaster. Crisis in the Red Zone makes clear that the outbreak of 2013–2014 is a harbinger of further, more severe outbreaks, and of emerging viruses heretofore unimagined—in any country, on any continent. In our ever more interconnected world, with roads and towns cut deep into the jungles of equatorial Africa, viruses both familiar and undiscovered are being unleashed into more densely populated areas than ever before.The more we discover about the virosphere, the more we realize its deadly potential. Crisis in the Red Zone is an exquisitely timely book, a stark warning of viral outbreaks to come.

    Its starting point is the annual Turing Test, which pits artificial intelligence programs against people to determine if computers can “think.”Named for computer pioneer Alan Turing, the Tur­ing Test convenes a panel of judges who pose questions—ranging anywhere from celebrity gossip to moral conundrums—to hidden contestants in an attempt to discern which is human and which is a computer. The machine that most often fools the panel wins the Most Human Computer Award. But there is also a prize, bizarre and intriguing, for the Most Human Human.In 2008, the top AI program came short of passing the Turing Test by just one astonishing vote. In 2009, Brian Christian was chosen to participate, and he set out to make sure Homo sapiens would prevail.The author’s quest to be deemed more human than a com­puter opens a window onto our own nature. Interweaving modern phenomena like customer service “chatbots” and men using programmed dialogue to pick up women in bars with insights from fields as diverse as chess, psychiatry, and the law, Brian Christian examines the philosophical, bio­logical, and moral issues raised by the Turing Test.One central definition of human has been “a being that could reason.” If computers can reason, what does that mean for the special place we reserve for humanity?

    . . alive and fascinating and provocative on every page."—Oliver Sacks, M.D.Porter's charting of the history of medicine affords readers the opportunity as never before to assess its culture and science and its costs and benefits to humankind. "A splendid and thoroughly engrossing book."--"L.A. Times." of illustrations.

    In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field—the study of life’s diversity and relatedness at the molecular level—is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection—a type of HGT.David Quammen chronicles these discoveries through the lives of the researchers who made them—such as Carl Woese, the most important little-known biologist of the twentieth century; Lynn Margulis, the notorious maverick whose wild ideas about “mosaic” creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health.

    Until recently scientists dis­missed these stories—waves that high would seem to violate the laws of physics. But in the past few decades, as a startling number of ships vanished and new evidence has emerged, oceanographers realized something scary was brewing in the planet’s waters. They found their proof in February 2000, when a British research vessel was trapped in a vortex of impossibly mammoth waves in the North Sea—including several that approached 100 feet.As scientists scramble to understand this phenomenon, others view the giant waves as the ultimate challenge. These are extreme surfers who fly around the world trying to ride the ocean’s most destructive monsters. The pioneer of extreme surfing is the legendary Laird Hamilton, who, with a group of friends in Hawaii, figured out how to board suicidally large waves of 70 and 80 feet. Casey follows this unique tribe of peo­ple as they seek to conquer the holy grail of their sport, a 100­-foot wave.In this mesmerizing account, the exploits of Hamilton and his fellow surfers are juxtaposed against scientists’ urgent efforts to understand the destructive powers of waves—from the tsunami that wiped out 250,000 people in the Pacific in 2004 to the 1,740-foot-wave that recently leveled part of the Alaskan coast.Like Jon Krakauer’s Into Thin Air, The Wave brilliantly portrays human beings confronting nature at its most ferocious.

    In captivity, octopuses have been known to identify individual human keepers, raid neighboring tanks for food, turn off lightbulbs by spouting jets of water, plug drains, and make daring escapes. How is it that a creature with such gifts evolved through an evolutionary lineage so radically distant from our own? What does it mean that evolution built minds not once but at least twice? The octopus is the closest we will come to meeting an intelligent alien. What can we learn from the encounter?In Other Minds, Peter Godfrey-Smith, a distinguished philosopher of science and a skilled scuba diver, tells a bold new story of how subjective experience crept into being—how nature became aware of itself. As Godfrey-Smith stresses, it is a story that largely occurs in the ocean, where animals first appeared. Tracking the mind’s fitful development, Godfrey-Smith shows how unruly clumps of seaborne cells began living together and became capable of sensing, acting, and signaling. As these primitive organisms became more entangled with others, they grew more complicated. The first nervous systems evolved, probably in ancient relatives of jellyfish; later on, the cephalopods, which began as inconspicuous mollusks, abandoned their shells and rose above the ocean floor, searching for prey and acquiring the greater intelligence needed to do so. Taking an independent route, mammals and birds later began their own evolutionary journeys.But what kind of intelligence do cephalopods possess? Drawing on the latest scientific research and his own scuba-diving adventures, Godfrey-Smith probes the many mysteries that surround the lineage. How did the octopus, a solitary creature with little social life, become so smart? What is it like to have eight tentacles that are so packed with neurons that they virtually “think for themselves”? What happens when some octopuses abandon their hermit-like ways and congregate, as they do in a unique location off the coast of Australia?By tracing the question of inner life back to its roots and comparing human beings with our most remarkable animal relatives, Godfrey-Smith casts crucial new light on the octopus mind—and on our own.

    Our memory is unreliable; we can't multiply large sums in our heads; advertising manipulates our judgment; we tend to distrust people who are different from us; supernatural beliefs and superstitions are hard to shake; we prefer instant gratification to long-term gain; and what we presume to be rational decisions are often anything but. Drawing on striking examples and fascinating studies, neuroscientist Dean Buonomano illuminates the causes and consequences of these "bugs" in terms of the brain's innermost workings and their evolutionary purposes. He then goes one step further, examining how our brains function-and malfunction-in the digital, predator-free, information-saturated, special effects-addled world that we have built for ourselves. Along the way, Brain Bugs gives us the tools to hone our cognitive strengths while recognizing our inherent weaknesses.

    To its adherents, it is an elegant statement about learning from experience. To its opponents, it is subjectivity run amok.In the first-ever account of Bayes' rule for general readers, Sharon Bertsch McGrayne explores this controversial theorem and the human obsessions surrounding it. She traces its discovery by an amateur mathematician in the 1740s through its development into roughly its modern form by French scientist Pierre Simon Laplace. She reveals why respected statisticians rendered it professionally taboo for 150 years—at the same time that practitioners relied on it to solve crises involving great uncertainty and scanty information (Alan Turing's role in breaking Germany's Enigma code during World War II), and explains how the advent of off-the-shelf computer technology in the 1980s proved to be a game-changer. Today, Bayes' rule is used everywhere from DNA de-coding to Homeland Security.Drawing on primary source material and interviews with statisticians and other scientists, The Theory That Would Not Die is the riveting account of how a seemingly simple theorem ignited one of the greatest controversies of all time.