In a lab filled with curiosities--beakers, microscopes, Bunsen burners, and hundreds upon hundreds of books--sat an investigator who would go on to crack at least two thousand cases in his forty-year career. Known as the "American Sherlock Holmes," Edward Oscar Heinrich was one of America's greatest--and first--forensic scientists, with an uncanny knack for finding clues, establishing evidence, and deducing answers with a skill that seemed almost supernatural.Heinrich was one of the nation's first expert witnesses, working in a time when the turmoil of Prohibition led to sensationalized crime reporting and only a small, systematic study of evidence. However with his brilliance, and commanding presence in both the courtroom and at crime scenes, Heinrich spearheaded the invention of a myriad of new forensic tools that police still use today, including blood spatter analysis, ballistics, lie-detector tests, and the use of fingerprints as courtroom evidence. His work, though not without its serious--some would say fatal--flaws, changed the course of American criminal investigation.Based on years of research and thousands of never-before-published primary source materials, American Sherlock captures the life of the man who pioneered the science our legal system now relies upon--as well as the limits of those techniques and the very human experts who wield them.

    Was the Battle of Hastings a French victory?Non! William the Conqueror was Norman and hated the French.Were the Brits really responsible for the death of Joan of Arc?Non! The French sentenced her to death for wearing trousers.Was the guillotine a French invention?Non! It was invented in Yorkshire.Ten centuries' worth of French historical 'facts' bite the dust as Stephen Clarke looks at what has really been going on since 1066 ...

    As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    Determined to clone an endangered flower—the rare ghost orchid Polyrrhiza lindenii—a deeply eccentric and oddly attractive man named John Laroche leads Orlean on an unforgettable tour of America’s strange flower-selling subculture, through Florida’s swamps and beyond, along with the Seminoles who help him and the forces of justice who fight him. In the end, Orlean—and the reader—will have more respect for underdog determination and a powerful new definition of passion.   In this new edition, coming fifteen years after its initial publication and twenty years after she first met the “orchid thief,” Orlean revisits this unforgettable world, and the route by which it was brought to the screen in the film Adaptation, in a new retrospective essay.

    Her unconventional upbringing transforms Beryl into a bold young woman with a fierce love of all things wild and an inherent understanding of nature’s delicate balance. But even the wild child must grow up, and when everything Beryl knows and trusts dissolves, she is catapulted into a string of disastrous relationships. Beryl forges her own path as a horse trainer, and her uncommon style attracts the eye of the Happy Valley set, a decadent, bohemian community of European expats who also live and love by their own set of rules. But it’s the ruggedly charismatic Denys Finch Hatton who ultimately helps Beryl navigate the uncharted territory of her own heart. The intensity of their love reveals Beryl’s truest self and her fate: to fly.

    The effects of homeopathy don’t go away under rigorous scientific conditions. The laws of nature aren’t what they used to be. Thirty years on, no one has an explanation for a seemingly intelligent signal received from outer space. The US Department of Energy is re-examining cold fusion because the experimental evidence seems too solid to ignore. The placebo effect is put to work in medicine while doctors can’t agree whether it even exists.In an age when science is supposed to be king, scientists are beset by experimental results they simply can’t explain. But, if the past is anything to go by, these anomalies contain the seeds of future revolutions. While taking readers on an entertaining tour d’horizon of the strangest of scientific findings – involving everything from our lack of free will to Martian methane that offers new evidence of life on the planet – Michael Brooks argues that the things we don’t understand are the key to what we are about to discover.This mind-boggling but entirely accessible survey of the outer limits of human knowledge is based on a short article by Michael Brooks for New Scientist magazine. It became the sixth most circulated story on the internet in 2005, and provoked widespread comment and compliments (Google “13 things that do not make sense” to see).Michael Brooks has now dug deeply into those mysteries, with extraordinary results.

    Minutes later her head was struck from her body with a single stroke of a heavy axe. Her death for high treason sent shockwaves through the Tudor world, and served as a gruesome reminder to all who aspired to a crown that the axe could fall at any time.Jane is known to history as "the Nine Days Queen," but her reign lasted, in fact, for thirteen days. The human and emotional aspects of her story have often been ignored, although she is remembered as one of the Tudor Era’s most tragic victims. While this is doubtlessly true, it is only part of the complex jigsaw of Jane’s story. She was a remarkable individual with a charismatic personality who earned the admiration and affection of many of those who knew her. All were impressed by her wit, passion, intelligence, and determined spirit. Furthermore, the recent trend of trying to highlight her achievements and her religious faith has, in fact, further obscured the real Jane, a young religious radical who saw herself as an advocate of the reformed faith—Protestantism—and ultimately became a martyr for it.Crown of Blood is an important and significant retelling of an often-misunderstood tale: set at the time of Jane’s downfall and following her journey through to her trial and execution, each chapter moves between the past and the “present,” using a rich abundance of primary source material (some of which has never been published) in order to paint a vivid picture of Jane’s short and turbulent life. This dramatic narrative traces the dangerous plots and web of deadly intrigue in which Jane became involuntarily tangled—and which ultimately led to a shocking and catastrophic conclusion.

    Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

    In 1969 we even walked on the moon. And yet as late as 2000, the earth’s deepest cave—the supercave—remained undiscovered. This is the story of the men and women who risked everything to find it, earning their place in history beside the likes of Peary, Amundsen, Hillary, and Armstrong. In 2004, two great scientist-explorers are attempting to find the bottom of the world. Bold, heroic American Bill Stone is committed to the vast Cheve Cave, located in southern Mexico and deadly even by supercave standards. On the other side of the globe, legendary Ukrainian explorer Alexander Klimchouk—Stone’s polar opposite in temperament and style, but every bit his equal in scientific expertise, physical bravery, and sheer determination—has targeted Krubera, a freezing nightmare of a supercave in the Republic of Georgia, where underground dangers are compounded by the horrors of separatist war in this former Soviet republic.

    Was it truly entombed in a Paris cellar for two hundred years? Or did it come from a secret Nazi bunker? Or from the moldy basement of a devilishly brilliant con artist? As Benjamin Wallace unravels the mystery, we meet a gallery of intriguing players—from the bicycle-riding British auctioneer who speaks of wines as if they are women to the obsessive wine collector who discovered the bottle. Suspenseful and thrillingly strange, this is the vintage tale of what could be the most elaborate con since the Hitler diaries.

    Constitution was amended to restrict one of America’s favorite pastimes: drinking alcoholic beverages. From its start, America has been awash in drink. The sailing vessel that brought John Winthrop to the shores of the New World in 1630 carried more beer than water. By the 1820s, liquor flowed so plentifully it was cheaper than tea. That Americans would ever agree to relinquish their booze was as improbable as it was astonishing. Yet we did, and Last Call is Daniel Okrent’s dazzling explanation of why we did it, what life under Prohibition was like, and how such an unprecedented degree of government interference in the private lives of Americans changed the country forever. Writing with both wit and historical acuity, Okrent reveals how Prohibition marked a confluence of diverse forces: the growing political power of the women’s suffrage movement, which allied itself with the antiliquor campaign; the fear of small-town, native-stock Protestants that they were losing control of their country to the immigrants of the large cities; the anti-German sentiment stoked by World War I; and a variety of other unlikely factors, ranging from the rise of the automobile to the advent of the income tax. Through it all, Americans kept drinking, going to remarkably creative lengths to smuggle, sell, conceal, and convivially (and sometimes fatally) imbibe their favorite intoxicants. Last Call is peopled with vivid characters of an astonishing variety: Susan B. Anthony and Billy Sunday, William Jennings Bryan and bootlegger Sam Bronfman, Pierre S. du Pont and H. L. Mencken, Meyer Lansky and the incredible—if long-forgotten—federal official Mabel Walker Willebrandt, who throughout the twenties was the most powerful woman in the country. (Perhaps most surprising of all is Okrent’s account of Joseph P. Kennedy’s legendary, and long-misunderstood, role in the liquor business.) It’s a book rich with stories from nearly all parts of the country. Okrent’s narrative runs through smoky Manhattan speakeasies, where relations between the sexes were changed forever; California vineyards busily producing “sacramental” wine; New England fishing communities that gave up fishing for the more lucrative rum-running business; and in Washington, the halls of Congress itself, where politicians who had voted for Prohibition drank openly and without apology. Last Call is capacious, meticulous, and thrillingly told. It stands as the most complete history of Prohibition ever written and confirms Daniel Okrent’s rank as a major American writer.

    In the first-ever history about the organization, New York Times bestselling author Annie Jacobsen draws on inside sources, exclusive interviews, private documents, and declassified memos to paint a picture of DARPA, or "the Pentagon's brain," from its Cold War inception in 1958 to the present.This is the book on DARPA--a compelling narrative about this clandestine intersection of science and the American military and the often frightening results.

    A thousand eyes see all I do.' Elizabeth IThe Tudor monarchs were constantly surrounded by an army of attendants, courtiers and ministers. Even in their most private moments, they were accompanied by a servant specifically appointed for the task. A groom of the stool would stand patiently by as Henry VIII performed his daily purges, and when Elizabeth I retired for the evening, one of her female servants would sleep at the end of her bed. These attendants knew the truth behind the glamorous exterior. They saw the tears shed by Henry VII upon the death of his son Arthur. They knew the tragic secret behind 'Bloody' Mary's phantom pregnancies. And they saw the 'crooked carcass' beneath Elizabeth I's carefully applied makeup, gowns and accessories. It is the accounts of these eyewitnesses, as well as a rich array of other contemporary sources that historian Tracy Borman has examined more closely than ever before. With new insights and discoveries, and in the same way that she brilliantly illuminated the real Thomas Cromwell - The Private Life of the Tudors will reveal previously unexamined details about the characters we think we know so well.

    As the Wrights labored to invent the airplane, Zeppelin fathered the wondrous airship, sparking a bitter rivalry between the two types of aircraft and their innovators that would last for decades in the quest to control one of humanity's most inspiring achievements.And it was the airship -- not the airplane -- that would lead the way. In the glittery 1920s, the count's brilliant protégé, Hugo Eckener, achieved undreamt-of feats of daring and skill, including the extraordinary Round-the-World Voyage of the Graf Zeppelin. At a time when America's airplanes -- rickety deathtraps held together by glue, screws, and luck -- could barely make it from New York to Washington, Eckener's airships serenely traversed oceans without a single crash, fatality, or injury. What Charles Lindbergh almost died doing -- crossing the Atlantic in 1927 -- Eckener effortlessly accomplished three years before the Spirit of St. Louis even took off. Even as the Nazis sought to exploit Zeppelins for their own nefarious purposes, Eckener built his masterwork, the behemoth Hindenburg -- a marvel of design and engineering. Determined to forge an airline empire under the new flagship, Eckener met his match in Juan Trippe, the ruthlessly ambitious king of Pan American Airways, who believed his fleet of next-generation planes would vanquish Eckener's coming airship armada.It was a fight only one man -- and one technology -- could win. Countering each other's moves on the global chessboard, each seeking to wrest the advantage from his rival, the two men's struggle for mastery of the air was not only the clash of technologies, but of business, diplomacy, politics, personalities, and their vastly different dreams of the future.Empires of the Sky is the sweeping, untold tale of the duel that transfixed the world and helped create our modern age.

    More than 3 billion miles from Earth, a small NASA spacecraft called New Horizons screamed past Pluto at more than 32,000 miles per hour, focusing its instruments on the long mysterious icy worlds of the Pluto system, and then, just as quickly, continued on its journey out into the beyond.Nothing like this has occurred in a generation--a raw exploration of new worlds unparalleled since NASA's Voyager missions to Uranus and Neptune--and nothing like it is planned to happen ever again. The photos that New Horizons sent back to Earth graced the front pages of newspapers on all 7 continents, and NASA's website for the mission received more than 2 billion hits in the days surrounding the flyby. At a time when so many think our most historic achievements are in the past, the most distant planetary exploration ever attempted not only succeeded but made history and captured the world's imagination.How did this happen? Chasing New Horizons is the story of the men and women behind the mission: of their decades-long commitment; of the political fights within and outside of NASA; of the sheer human ingenuity it took to design, build, and fly the mission; and of the plans for New Horizons' next encounter, 1 billion miles past Pluto. Told from the insider's perspective of Dr. Alan Stern--the man who led the mission--Chasing New Horizons is a riveting story of scientific discovery, and of how far humanity can go when people focused on a dream work together toward their incredible goal.