As recently as 1918, a pandemic of influenza claimed over 50 million lives worldwide. The advent of drugs and vaccines led to an era of hope when we thought our battles with infectious disease were won, but our optimism has been eroded by the recognition that many pathogens have the capacity to transform themselves and escape our efforts to eradicate them. Are we now facing an inevitable repeat of a calamity such as the 1918 influenza pandemic or the Black Death? Can we anticipate and thwart such an event, or are we wilfully creating the conditions that would promote the emergence of new and highly virulent human infectious disease?Sunetra Gupta is Professor of Theoretical Epidemiology at the University of Oxford specialising in infectious diseases. She holds a bachelor's degree from Princeton University and a Ph.D. from the University of London. She has been awarded the Scientific Medal by the Zoological Society of London and the Royal Society Rosalind Franklin Award for her scientific research. She is also a novelist whose books have been awarded the Sahitya Akademi Award, the Southern Arts Literature Prize, shortlisted for the Crossword Award, and longlisted for the DSC and Orange Prizes.

    Each of the ten chapters is a virtual time capsule which reminds, as we plunge headlong into the future, of the richness and importance of our past. Illustrations throughout.

    In 2006, the National Institute of Mental Health estimated that 40 million adult Americans suffer from an anxiety disorder in any given year: more than double the number thought to have such a disorder in 2001. Anti-anxiety drugs are a billion-dollar business. Yet as recently as 1955, when the first tranquilizer—Miltown—went on the market, pharmaceutical executives worried that there wouldn’t be interest in anxiety-relief. At mid-century, talk therapy remained the treatment of choice.But Miltown became a sensation—the first psychotropic blockbuster in United States history. By 1957, Americans had filled 36 million prescriptions. Patients seeking made-to-order tranquility emptied drugstores, forcing pharmacists to post signs reading “more Miltown tomorrow.” The drug’s financial success and cultural impact revolutionized perceptions of anxiety and its treatment, inspiring the development of other lifestyle drugs including Valium and Prozac.In The Age of Anxiety, Andrea Tone draws on a broad array of original sources—manufacturers’ files, FDA reports, letters, government investigations, and interviews with inventors, physicians, patients, and activists—to provide the first comprehensive account of the rise of America’s tranquilizer culture. She transports readers from the bomb shelters of the Cold War to the scientific optimism of the Baby Boomers, to the “just say no” Puritanism of the late 1970s and 1980s.A vibrant history of America’s long and turbulent affair with tranquilizers, The Age of Anxiety casts new light on what it has meant to seek synthetic solutions to everyday angst.

    Gill traverses the Atlantic to become the freshest chronicler of American identity in recent memory. With a fiery temper, a sharp-tongued wit, and an insatiable curiosity to figure out what makes more than 300 million of the world’s population tick, Gill traces the history and logic of our nation’s habits, collecting wild stories and startling facts along the way. From Colorado, where he meets a local vegeta­tion expert and learns which flowers were in Poca­hontas’s nuptial bouquet, to Kentucky, where he visits the Creationist Museum and drinks moonshine with a hog farmer, and to Harlem, where he misses a turn and stumbles into the wrong barbershop for a once-in-a-lifetime haircut, Gill embarks on a tour of not only the nation’s landscape but also its psyche, playing adventurer, philosopher, statistician, and raconteur all at once. In inimitable fashion he explains why pressing a button in a Manhattan elevator means entering a social contract of American etiquette and inverting conventional hierarchies of space; why browsing through Playboy centerfolds becomes the perfect litmus test for a generation’s political views; and how Hollywood is the metaphysical marketplace for movies, the place where Americans are sold on American romance and taught how to dream the American dream.Weaving together a tapestry of historical erudition and outrageous anecdotes, Gill ultimately captures the scope and spirit of a nation that started off as a conceptual experiment and became a political, sci­entific, and cultural fortress. This humorous and revelatory book shows us why we are who we are by transforming ordinary experiences into extraordinary lessons and promising to never let us look in the mirror the same way again.

    Communities where heroin had never been seen before—from Charlotte, NC and Huntington, WVA, to Salt Lake City and Portland, OR—were overrun with it. Local police and residents were stunned. How could heroin, long considered a drug found only in the dense, urban environments along the East Coast, and trafficked into the United States by enormous Colombian drug cartels, be so incredibly ubiquitous in the American heartland? Who was bringing it here, and perhaps more importantly, why were so many townspeople suddenly eager for the comparatively cheap high it offered?With the same dramatic drive of El Narco and Methland, Sam Quinones weaves together two classic tales of American capitalism: The stories of young men in Mexico, independent of the drug cartels, in search of their own American Dream via the fast and enormous profits of trafficking cheap black-tar heroin to America’s rural and suburban addicts; and that of Purdue Pharma in Stamford, Connecticut, determined to corner the market on pain with its new and expensive miracle drug, Oxycontin; extremely addictive in its own right. Quinones illuminates just how these two stories fit together as cause and effect: hooked on costly Oxycontin, American addicts were lured to much cheaper black tar heroin and its powerful and dangerous long-lasting high. Embroiled alongside the suppliers and buyers are DEA agents, local, small-town sheriffs, and the US attorney from eastern Virginia whose case against Purdue Pharma and Oxycontin made him an enemy of the Bush-era Justice Department, ultimately stalling and destroying his career in public service.Dreamland is a scathing and incendiary account of drug culture and addiction spreading to every part of the American landscape.

    They exhibit an extreme passion for freedom of choice—which has turned law circumvention into an art and has made them incapable of comprehending words like “discipline,” “co-ordination,” or “system.” There's no such thing as a meek GreekA Greek cannot talk unless he has his hands free, and a soft-spoken Greek is one who can be heard only as far as across the street. Two Greeks having an amiable conversation sound as if they are ready to murder each other, and a party of exuberant Greeks having a good time could be described as a pack of hounds that has just sighted the fox. Free spiritsMercurial in the extreme, the Greeks' temperament flourishes uninhibited throughout their waking hours. This is probably why the ancient sages saw fit to carve their maxims “Nothing in excess” and “Know thyself” on the portals of the Delphic Oracle, in an attempt to persuade their fellow Greeks to curb their emotions. They were not heeded then any more than they are now. How much does a Greek urn?In general, Greeks believe in free trade, fair dealing, and keeping one's word. They are quick at grasping (and inventing) complicated business and financial arrangements and they are past masters in acting as middlemen—which means that they are paid by both parties while risking nothing themselves.

    By the time the fires consuming black churches and schools were put out, forty-six freed people had been murdered. Congress, furious at this and other evidence of white resistance in the conquered South, launched what is now called Radical Reconstruction, policies to ensure the freedom of the region’s four million blacks—and one of the most remarkable experiments in American history.    Stephen V. Ash’s A Massacre in Memphis is a portrait of a Southern city that opens an entirely new view onto the Civil War and its aftermath. A momentous national event, the riot is also remarkable for being “one of the best-documented episodes of the American nineteenth century.” Yet Ash is the first to mine the sources available to full effect. Bringing postwar Memphis to vivid life, he takes us among newly arrived Yankees, former Rebels, boisterous Irish immigrants, and striving freed people, and shows how Americans of the period worked, prayed, expressed their politics, and imagined the future. And how they died: Ash’s harrowing and profoundly moving present-tense narration of the riot has the immediacy of the best journalism.    Told with nuance, grace, and a quiet moral passion, A Massacre in Memphis is Civil War–era history like no other.

    Though lesser known than other wars the US has fought over the years, it was an important conflict that set the stage for the US to earn a reputation as a respected nation that could demonstrate power on foreign lands as well as its homeland…   PLEASE NOTE: This is key takeaways and analysis of the book and NOT the original book.    Inside this Instaread of Thomas Jefferson and the Tripoli Pirates: Overview of the book Important People Key Takeaways Analysis of Key Takeaways   About the Author With Instaread, you can get the key takeaways and analysis of a book in 15 minutes. We read every chapter, identify the key takeaways and analyze them for your convenience.

    Orphaned as a teenager, he came to America in search of an education, a home, and the war that would at last bring him fame and honor. As George Washington’s most trusted aide, Hamilton helped to win the American Revolution—but after the war, his enemies lost no time accusing him of trying to sell his country back to the British. He was the most powerful member of Washington’s presidential cabinet—so why did Adams and Jefferson hate him so much?In this book, you will learn how the author of the Federalist Papers and the first Secretary of the Treasury nearly ruined his career by fighting duels, seducing women, and getting involved in America’s first sex scandal. The duel that killed Alexander Hamilton is the most famous duel in American history, but you’ll have to come up with your own answer to its greatest mystery: who shot first, Hamilton or Burr?

    

    That is until 1904, when the disease broke out in a household in Oyster Bay, Long Island. Authorities suspected the family cook, Mary Mallon, of being a carrier. But before she could be tested, the woman, soon to be known as Typhoid Mary, had disappeared. Over the course of the next three years, Mary worked at several residences, spreading her pestilence as she went. In 1907, she was traced to a home on Park Avenue, and taken into custody. Institutionalized at Riverside Hospital for three years, she was released only when she promised never to work as a cook again. She promptly disappeared.For the next five years Mary worked in homes and institutions in and around New York, often under assumed names. In February 1915, a devastating outbreak of typhoid at the Sloane Hospital for Women was traced to her. She was finally apprehended and reinstitutionalized at Riverside Hospital, where she would remain for the rest of her life.Typhoid Mary is the story of her infamous life. Anthony Bourdain reveals the seedier side of the early 1900s, and writes with his renowned panache about life in the kitchen, uncovering the horrifying conditions that allowed the deadly spread of typhoid over a decade. Typhoid Mary is a true feast for history lovers and Bourdain lovers alike.

    Brinkley–America’s most brazen young con man–arrived in the tiny town of Milford, Kansas. He set up a medical practice and introduced an outlandish surgical method using goat glands to restore the fading virility of local farmers.It was all nonsense, of course, but thousands of paying customers quickly turned “Dr.” Brinkley into America’s richest and most famous surgeon. His notoriety captured the attention of the great quackbuster Morris Fishbein, who vowed to put the country’s “most daring and dangerous” charlatan out of business.Their cat-and-mouse game lasted throughout the 1920s and ’30s, but despite Fishbein’s efforts Brinkley prospered wildly. When he ran for governor of Kansas, he invented campaigning techniques still used in modern politics. Thumbing his nose at American regulators, he built the world’s most powerful radio transmitter just across the Rio Grande to offer sundry cures, and killed or maimed patients by the score, yet his warped genius produced innovations in broadcasting that endure to this day. By introducing country music and blues to the nation, Brinkley also became a seminal force in rock ’n’ roll. In short, he is the most creative criminal this country has ever produced.Culminating in a decisive courtroom confrontation that pit Brinkley against his nemesis Fishbein, Charlatan is a marvelous portrait of a boundlessly audacious rogue on the loose in an America that was ripe for the bamboozling.

    Conventional wisdom may be wrong. In this controversial book, the eminent biologist Paul W. Ewald offers some startling arguments:-Germs appear to be at the root of heart disease, Alzheimer’s, schizophrenia, many forms of cancer, and other chronic diseases.-The greatest threats to our health come not from sensational killers such as Ebola, West Nile virus, and super-virulent strains of influenza, but from agents that are already here causing long-term infections, which eventually lead to debilitation and death. -The medical establishment has largely ignored the evidence that implicates these germs, to the detriment of our public health.-New evolutionary theories are available, which explain how germs function and offer opportunities for controlling these modern plagues — if we are willing to listen to them.Plague Time is an eye-opening exploration of the revolutionary new understanding of disease that may set the course of medical research for the twenty-first century.

    This updated edition of David Walley's cutting-edge classic includes a new foreword, a substantial chapter carrying the Zappa saga through his death from cancer, an afterword, bibliography, discography, videography, and guide to Zappa on the Internet. From 1960's Freak Out! to the posthumous Civilization Phaze III, No Commercial Potential offers converts and connoisseurs the most practical and penetrating book ever written on the musical phenomenon known as Frank Zappa.

    You may find it for free on the web. Purchase of the Kindle edition includes wireless delivery.