We like to imagine that it’s based on evidence and the results of fair tests. In reality, those tests are often profoundly flawed. We like to imagine that doctors are familiar with the research literature surrounding a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by industry. We like to imagine that regulators let only effective drugs onto the market, when in reality they approve hopeless drugs, with data on side effects casually withheld from doctors and patients.All these problems have been protected from public scrutiny because they’re too complex to capture in a sound bite. But Dr. Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct on a global scale affects us. In his own words, “the tricks and distortions documented in these pages are beautiful, intricate, and fascinating in their details.” With Goldacre’s characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for something to be done. This is the pharmaceutical industry as it has never been seen before.

    “Curiouser and curiouser” —fun and fascinating facts from the world of drugs. Following in the tradition of The Ultimate Book of Useless Information, The Curious World of Drugs and Their Friends is a wry potpourri of interesting information about every conceivable kind of drug. Readers can feed their heads with anecdotes, facts, lists, statistics, and illustrations, including: • The test results of animals on LSD—cats lose their fear of dogs, and goats walk in geometric patterns • Drugs found in nature, from magic mushrooms to St. John’s wort to beaver secretions • Celebrities who overdosed at age 27—Jimi Hendrix, Janis Joplin, Jim Morrison, Kurt Cobain, Brian Jones, and Jean Michel-Basquiat • Imaginary drugs in literature and film, from spice the mélange in Dune to Moloko plus in A Clockwork Orange • Nicknames for a joint—from doobie to giggly stick to Mr. Boom Bizzle • The global percentages of adults who have used cannabis—.004 percent in Singapore and 12.6 percent in the United States • The uses of opium in ancient Rome—from treatments for insomnia and epilepsy to colic and deafness • The most glamorous rehab clinics and their celebrity alumni • Mini-biographies of the biggest drug kingpins around the world Wacky but well-researched, unbiased and shameless, The Curious World of Drugs and Their Friends dares to take readers on a long, strange trivia trip.

    Told through an examination of animal and plant life today - with occasional juxtapositions of extinct fossil forms to reveal the origin of living creatures - "Life on Earth" is an astonishing pageant of life, with a cast of characters drawn from the whole range of living animals the world over. Attenborough's perceptive, dynamic approach to the evolution of some four million species of living organisms that populate the planet is to trace the most significant thread in the history of each major group. He then proceeds to explain from the evidence of living representatives and fossil remains why certain animals adapted and survived, evolved to more complex and "higher" forms of life, while others, by some inherent limitation imposed by their physiology or structure, failed and became extinct. "Life on Earth" is a book of wonders. A model of clarity and ease as a guide, Attenborough takes the reader around the world with him into jungles where orchids have petals that "impersonate" wasps to attract pollinating insects; to Australia, where honeypot ants force feed nectar to workers of a special caste, then hang them up by their forelegs like living storage jars; to remote mountains in Japan where little monkeys called macaques have learned to combat the winter snows by bathing in hot volcanic springs.

    This introductory book provides an overview of the key theoretical principles of human sociobiology and evolutionary psychology and shows how they illuminate the ways humans think and behave. The book takes as one of its main premises the idea that we think, feel, and act in ways that once enhanced the reproductive success of our ancestors.The book covers fundamental issues such as the origins and function of sexual reproduction, mating behavior, human mate choice, patterns of violence in families, altruistic behavior, the evolution of brain size and the origins of language, the modular mind, and the relationship between genes and culture. It also examines the larger implications of Darwinism for how we view ourselves as a species and our sense of ourselves as a moral animal. The book includes a valuable historical introduction to evolutionary theories of behavior and concludes with an examination of the social and political ramifications of evolutionary thought. It contains numerous diagrams and illustrations, comprehensive references, summaries, and suggestions for further reading.

    After barely surviving the agony of smallpox themselves, they flouted eighteenth-century medicine by borrowing folk knowledge from African slaves and Eastern women in frantic bids to protect their children. From their heroic struggles stems the modern science of immunology as well as the vaccinations that remain our only hope should the disease ever be unleashed again.Jennifer Lee Carrell transports readers back to the early eighteenth century to tell the tales of Lady Mary Wortley Montagu and Dr. Zabdiel Boylston, two iconoclastic figures who helped save London and Boston from the deadliest disease mankind has known.

    No human being who stood on her decks that fateful night was alive to commemorate the event on its 100th anniversary. Their stories are with us, however, and the lessons remain. From the moment the world learned the Titanic had sunk, we wanted to know, who had survived? Those answers didn’t come until the evening of Thursday, April 18, 1912―when the Cunard liner Carpathia finally reached New York with the 706 survivors who had been recovered from Titanic’s lifeboats. Harold Bride, “Titanic’s surviving wireless operator,” relayed the story of the ship’s band. “The way the band kept playing was a noble thing. I heard it first while still we were working wireless when there was a ragtime tune for us. The last I saw of the band, when I was floating out in the sea with my lifebelt on, it was still on deck playing ‘Autumn.’ How they ever did it I cannot imagine.” There were stories of heroism―such as that of Edith Evans, who was waiting to board collapsible Lifeboat D, the last boat to leave Titanic, when she turned to Caroline Brown and said, “You go first. You have children waiting at home.” The sacrifice cost Evans her life, but as Mrs. Brown said later, “It was a heroic sacrifice, and as long as I live I shall hold her memory dear as my preserver, who preferred to die so that I might live.” There was mystery. There was bravery. There was suspense. There was cowardice. Most men who survived found themselves trying to explain how they survived when women and children had died. But mostly, there was loss. On her return to New York after picking up Titanic’s survivors, Carpathia had become known as a ship of widows. Rene Harris, who lost her husband, Broadway producer Henry Harris, in the disaster, later spoke of her loss when she said, “It was not a night to remember. It was a night to forget.” Drawing on a wealth of previously unpublished letters, memoirs, and diaries as well as interviews with survivors and family members, veteran author and writer Alan Rockwell brings to life the colorful voices and the harrowing experiences of many of those who lived to tell their story. More than 100 years after the RMS Titanic met its fatal end, the story of the tragic wreck continues to fascinate people worldwide. Though many survivors and their family members disappeared into obscurity or were hesitant to talk about what they went through, others were willing to share their experiences during the wreck and in its aftermath. This book recounts many of these first-hand accounts in graphic, compelling detail.

    This book provides the first complete identification guides to the birds of this teeming tropical paradise. It gives descriptions of 820 regional species, illustrated in 88 specially commissioned color plates accompanied by notes detailing distinctive features and habitats. Entries cover nomenclature, plumage, markings, voice, global range, distribution and regional status, habits, and diet. The main text gives practical information on where to find many exotic species, citing major birdwatching locations. Introductory chapters discuss habitats, climate, land-use, and conservation concerns. Professional ornithologists and amateur bird watchers alike will find this the indispensable bird guide for eastern Malaysia and western Indonesia for many years to come. It is also an unrivalled source of information for casual travellers and ecotourists.

    In this first anthology of its kind, Carey chooses accounts by scientists themselves--astronomers and physicists, biologists, chemists, psychologists--that are both arrestingly written and clear. Contributors include Carl Sagan, Charles Darwin, Stephen Jay Gould, Oliver Sacks, Lewis Thomas, Rachel Carson, Sigmund Freud, Henry David Thoreau, Mark Twain, and scores of others.

    Taking as territory everything from the Big Bang to the rise of civilization, Bryson seeks to understand how we got from there being nothing at all to there being us. To that end, he has attached himself to a host of the world’s most advanced (and often obsessed) archaeologists, anthropologists, and mathematicians, travelling to their offices, laboratories, and field camps. He has read (or tried to read) their books, pestered them with questions, apprenticed himself to their powerful minds. A Short History of Nearly Everything is the record of this quest, and it is a sometimes profound, sometimes funny, and always supremely clear and entertaining adventure in the realms of human knowledge, as only Bill Bryson can render it. Science has never been more involving or entertaining.

    He was eager to begin his first practice, but it turned out to be more than he bargained for. In just two years, in September, 1918, the entire village was sickened in rapid succession in the flu pandemic that killed quickly and indiscriminately throughout the world. It was wartime, and Nixon was unable to find help., This story is an up close and personal account of what it was like to be sick with the HINI type virus in 1918. It is a tale of a dedicated doctor whose selflessness, compassion and courage helped the villagers survive in the pandemic that killed more people in a year than the Black Death killed in a century...

    A parable about compassion-and the absence of it-Dark Remedy is a gripping account of thalidomide's extraordinary impact on the lives of individuals and nations over half a century.

    Completely overwhelmed and wrapped in stifling protective suits, he and his team took it in turns to provide care to patients while removing dead bodies from the ward. Against all odds he battled to keep the hospital open, as the queue of sick and dying patients grew every day. Only a few miles down the road the Irish Ambassador and Head of Irish Aid worked relentlessly to rapidly scale up the international response. At a time when entire districts had been quarantined, she travelled around the country, and met with UN agencies, the President and senior ministers so as to be better placed in alerting the world to the catastrophe unfolding in front of her.In this blow-by-blow account, Walsh and Johnson expose the often shocking shortcomings of the humanitarian response to the outbreak, both locally and internationally, and call our attention to the immense courage of those who put their lives on the line every day to contain the disease. Theirs is the definitive account of the fight against an epidemic that shook the world.

    Integrated central case studies woven throughout each chapter, use real-life stories to give you a tangible and engaging framework around which to learn and understand the science behind environmental issues. Printed on FSC (Forest Stewardship Council) certified paper, the newly revised Fourth Edition engages you through the addition of new EnvisionIt photo essays.

    But how did we acquire the most advanced form of communication on Earth? Daniel L. Everett, a “bombshell” linguist and “instant folk hero” (Tom Wolfe, Harper’s), provides in this sweeping history a comprehensive examination of the evolutionary story of language, from the earliest speaking attempts by hominids to the more than seven thousand languages that exist today.Although fossil hunters and linguists have brought us closer to unearthing the true origins of language, Daniel Everett’s discoveries have upended the contemporary linguistic world, reverberating far beyond academic circles. While conducting field research in the Amazonian rainforest, Everett came across an age-old language nestled amongst a tribe of hunter-gatherers. Challenging long-standing principles in the field, Everett now builds on the theory that language was not intrinsic to our species. In order to truly understand its origins, a more interdisciplinary approach is needed—one that accounts as much for our propensity for culture as it does our biological makeup.Language began, Everett theorizes, with Homo Erectus, who catalyzed words through culturally invented symbols. Early humans, as their brains grew larger, incorporated gestures and voice intonations to communicate, all of which built on each other for 60,000 generations. Tracing crucial shifts and developments across the ages, Everett breaks down every component of speech, from harnessing control of more than a hundred respiratory muscles in the larynx and diaphragm, to mastering the use of the tongue. Moving on from biology to execution, Everett explores why elements such as grammar and storytelling are not nearly as critical to language as one might suspect.In the book’s final section, Cultural Evolution of Language, Everett takes the ever-debated “language gap” to task, delving into the chasm that separates “us” from “the animals.” He approaches the subject from various disciplines, including anthropology, neuroscience, and archaeology, to reveal that it was social complexity, as well as cultural, physiological, and neurological superiority, that allowed humans—with our clawless hands, breakable bones, and soft skin—to become the apex predator.How Language Began ultimately explains what we know, what we’d like to know, and what we likely never will know about how humans went from mere communication to language. Based on nearly forty years of fieldwork, Everett debunks long-held theories by some of history’s greatest thinkers, from Plato to Chomsky. The result is an invaluable study of what makes us human.