Best of
Genetics

2005

Power, Sex, Suicide: Mitochondria and the Meaning of Life


Nick Lane - 2005
    Indeed, these tiny structures inside our cells are important beyond imagining. Without mitochondria, we would have no cell suicide, no sculpting of embryonic shape, no sexes, no menopause, no aging.In this fascinating and thought-provoking book, Nick Lane brings together the latest research in this exciting field to show how our growing insight into mitochondria has shed light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. These findings are of fundamental importance, both in understanding life on Earth, but also in controlling our own illnesses, and delaying our degeneration and death. Readers learn that two billion years ago, mitochondria were probably bacteria living independent lives and that their capture within larger cells was a turning point in the evolution of life, enabling the development of complex organisms. Lane describes how mitochondria have their own DNA and that its genes mutate much faster than those in the nucleus. This high mutation rate lies behind our aging and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer. We also discover that mitochondrial DNA is passed down almost exclusively via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to "Mitochondrial Eve," giving us vital information about our evolutionary history.Written by Nick Lane, a rising star in popular science, Power, Sex, Suicide is the first book for general readers on the nature and function of these tiny, yet fascinating structures.

Endless Forms Most Beautiful: The New Science of Evo Devo and the Making of the Animal Kingdom


Sean B. Carroll - 2005
    Evo Devo Evolutionary Developmental Biology is the new science that has finally cracked open the box. Within the pages of his rich and riveting book, Sean B. Carroll explains how we are discovering that complex life is ironically much simpler than anyone ever expected.

Evolution in Four Dimensions: Genetic, Epigenetic, Behavioral, and Symbolic Variation in the History of Life


Eva Jablonka - 2005
    New findings in molecular biology challenge the gene-centered version of Darwinian theory according to which adaptation occurs only through natural selection of chance DNA variations. In Evolution in Four Dimensions, Eva Jablonka and Marion Lamb argue that there is more to heredity than genes. They trace four dimensions in evolution -- four inheritance systems that play a role in evolution: genetic, epigenetic (or non-DNA cellular transmission of traits), behavioral, and symbolic (transmission through language and other forms of symbolic communication). These systems, they argue, can all provide variations on which natural selection can act. Evolution in Four Dimensions offers a richer, more complex view of evolution than the gene-based, one-dimensional view held by many today. The new synthesis advanced by Jablonka and Lamb makes clear that induced and acquired changes also play a role in evolution. After discussing each of the four inheritance systems in detail, Jablonka and Lamb put Humpty Dumpty together again by showing how all of these systems interact. They consider how each may have originated and guided evolutionary history and they discuss the social and philosophical implications of the four-dimensional view of evolution. Each chapter ends with a dialogue in which the authors engage the contrarieties of the fictional (and skeptical) I.M., or Ifcha Mistabra -- Aramaic for the opposite conjecture -- refining their arguments against I.M.'s vigorous counterarguments. The lucid and accessible text is accompanied by artist-physician Anna Zeligowski's lively drawings, which humorously and effectively illustrate the authors' points.

Genetic Entropy & the Mystery of the Genome


John C. Sanford - 2005
    John Sanford, a retired Cornell Professor, shows in "Genetic Entropy and the Mystery of the Genome" that the "Primary Axiom" is false. The Primary Axiom is the foundational evolutionary premise -- that life is merely the result of mutations and natural selection. In addition to showing compelling theoretical evidence that whole genomes must in fact degenerate over time, this book strongly refutes the Darwinian concept that man is just the result of a random and pointless natural process. This is an updated version of the October 2005 edition, which includes both a new appendix and glossary.

Genesis: The Scientific Quest for Life's Origin


Robert M. Hazen - 2005
    Though the process obeyed all the rules of chemistry and physics, the details of that original event pose as deep a mystery as any facing science. How did non-living chemicals become alive? While the question is (deceivingly) simple, the answers are unquestionably complex. Science inevitably plays a key role in any discussion of life's origins, dealing less with the question of why life appeared on Earth than with where, when, and how it emerged on the blasted, barren face of our primitive planet. Astrobiologist Robert Hazen has spent many years dealing with the fundamental questions of life's genesis. As an active research scientist, he is down deep in all the messy details that science has to offer on the subject, tracing the inexorable sequence of events that led to the complicated interactions of carbonbased molecules. As he takes us through the astounding process of emergence, we are witness to the first tentative steps toward life?from the unfathomable abundance of carbon biomolecules synthesized in the black vacuum of space to the surface of the Earth to deep within our planet's restless crust. We are privy to the breathtaking drama that rapidly unfolds as life prevails. The theory of emergence is poised to answer a multitude of questions?even as it raises the possibility that natural processes exist beyond what we now know, perhaps beyond what we even comprehend. Genesis tells the tale of transforming scientific advances in our quest for life's origins. Written with grace, beauty, and authority, it goes directly to the heart of who we are and why we are here.

Slave Species of God: The Story of Humankind from the Cradle of Humankind


Michael Tellinger - 2005
    Were humans created by God as Slaves? Was Abraham the first human Spy? Was Jesus an accidental Messiah? This work takes readers on a odyssey of the origins of humankind drawing on analogies between discoveries in genetic engineering and ancient archaeological finds.

The Complete Ball Python: A Comprehensive Guide to Care, Breeding and Genetic Mutations


Kevin McCurley - 2005
    A comprehensive guide with chapters discussing the ball python in nature, captivity, diet, selection, understanding the ball python, health concerns, breeding and egg incubation, baby snake care, color morphs, and more. Over 100 different genetic morphs are illustrated and discussed. Over 300 full-color photographs. Hardcover w/ Dj. ISBN 9780971319704

Making Sense of Heritability


Neven Sesardić - 2005
    He critically examines the view--very widely accepted by scientists, social scientists and philosophers of science--that heritability estimates have no causal implications and are devoid of any interest and subjects the arguments to close philosophical scrutiny. His conclusion is that anti-heritability arguments are based on conceptual confusions and misunderstandings of behavioral genetics.

Seven Deadly Colours: The Genius Of Nature's Palette And How It Eluded Darwin


Andrew Parker - 2005
    With fascinating examples of how colour has affected flora and fauna in different environments across the globe.

Robustness and Evolvability in Living Systems


Andreas Wagner - 2005
    Despite this instability, most animals do not grow two heads or die, plants continue to thrive, and bacteria continue to divide. Robustness and Evolvability in Living Systems tackles this perplexing paradox. The book explores why genetic changes do not cause organisms to fail catastrophically and how evolution shapes organisms' robustness. Andreas Wagner looks at this problem from the ground up, starting with the alphabet of DNA, the genetic code, RNA, and protein molecules, moving on to genetic networks and embryonic development, and working his way up to whole organisms. He then develops an evolutionary explanation for robustness.Wagner shows how evolution by natural selection preferentially finds and favors robust solutions to the problems organisms face in surviving and reproducing. Such robustness, he argues, also enhances the potential for future evolutionary innovation. Wagner also argues that robustness has less to do with organisms having plenty of spare parts (the redundancy theory that has been popular) and more to do with the reality that mutations can change organisms in ways that do not substantively affect their fitness.Unparalleled in its field, this book offers the most detailed analysis available of all facets of robustness within organisms. It will appeal not only to biologists but also to engineers interested in the design of robust systems and to social scientists concerned with robustness in human communities and populations.

Concepts of Genetics


William S. Klug - 2005
    The authors capture students' interest with up-to-date coverage of cutting edge topics and research. This text will help students connect the science of genetics to the issues of today through interesting and thought-provoking applications. The sixth edition boasts the next generation of media integration including Gen CD-X (student CD-ROM and Companion Website).

A New History of Ireland, Volume I: Prehistoric and Early Ireland


Dáibhí Ó Cróinín - 2005
    In this first volume of the Royal Irish Academy's multi-volume A New History of Ireland a wide range of national and international scholars, in every field of study, have produced studies of the archaeology, art, culture, geography, geology, history, language, law, literature, music, and related topics that include surveys of all previous scholarship combined with the latest research findings, to offer readers the first truly comprehensive and authoritative account of Irish history from the dawn of time down to the coming of the Normans in 1169.Included in the volume is a comprehensive bibliography of all the themes discussed in the narrative, together with copious illustrations and maps, and a thorough index.

Let Them Eat Precaution: How Politics Is Undermining the Genetic Revolution in Agriculture


Jon Entine - 2005
    More nutritious food is now produced with less environmental costs because genetically modified crops require almost no pesticides. Vitamin-enhanced crops and foods are helping to reduce malnutrition in parts of the developing world, and a wave of bio- pharmaceuticals is being developed. Yet, for all its achievements and promise, agricultural biotechnology is under intense fire from advocacy groups warning of Frankenfoods and fanning fear of a corporate takeover of agriculture by biotech firms. Mired in a rancorous trade and cultural war between Europe and the United States and inflamed by a politicized media, this technology remains dramatically underutilized, with particularly tragic consequences for millions of starving people in Africa and other poverty-stricken regions.