The fascinating story of the golden period from the revelation of the double helix of DNA to the cracking of the genetic code and first glimpses of gene regulation is told largely in the words of the main players, all of whom Judson interviewed extensively. The result is a book widely regarded as the best history of recent biological science yet published.This commemorative edition, honoring the memory of the author who died in 2011, contains essays by his daughter Olivia Judson, Matthew Meselson, and Mark Ptashne and an obituary by Jason Pontin. It contains all the content added to previous editions, including essays on some of the principal historical figures involved, such as Rosalind Franklin, and a sketch of the further development of molecular biology in the era of recombinant DNA.

    critical analysis of the latest work in prenatal diagnosis of genetic and other disorders. Topics include: fragile X syndrome, cystic fibrosis, neural tube defects, and hemoglobinopathies; the experience and techniques of amniocentesis, chorionic villus sampling, ultrasound, fetal blood sampling; abortion and fetal therapy; and medicolegal and ethical issues in prenatal diagnosis. The book describes the use of combined biochemical markers to screen for neural tube and chromosomal defects, presents the latest developments relating to testing fetal cells in the mother's blood, and reviews major advances in molecular genetics that permit prenatal carrier detection and presymptomatic and predictive testing.