Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

    Yet despite a century of medical progress, viral and bacterial disasters continue to take us by surprise, inciting panic and dominating news cycles. From the Spanish flu to the 1924 outbreak of pneumonic plague in Los Angeles to the 1930 “parrot fever” pandemic, through the more recent SARS, Ebola, and Zika epidemics, the last one hundred years have been marked by a succession of unanticipated pandemic alarms.In The Pandemic Century, a lively account of scares both infamous and less known, Mark Honigsbaum combines reportage with the history of science and medical sociology to artfully reconstruct epidemiological mysteries and the ecology of infectious diseases. We meet dedicated disease detectives, obstructive or incompetent public health officials, and brilliant scientists often blinded by their own knowledge of bacteria and viruses. We also see how fear of disease often exacerbates racial, religious, and ethnic tensions—even though, as the epidemiologists Malik Peiris and Yi Guan write, “‘nature’ remains the greatest bioterrorist threat of all.”Like man-eating sharks, predatory pathogens are always present in nature, waiting to strike; when one is seemingly vanquished, others appear in its place. These pandemics remind us of the limits of scientific knowledge, as well as the role that human behavior and technologies play in the emergence and spread of microbial diseases.

    It was in search of the fabled Spice Islands and their cloves that Magellan charted the first circumnavigation of the globe. Vasco da Gama sailed the dangerous waters around Africa to India on a quest for Christians--and spices. Columbus sought gold and pepper but found the New World. By the time these fifteenth- and sixteenth-century explorers set sail, the aromas of these savory, seductive seeds and powders had tempted the palates and imaginations of Europe for centuries. "Spice: The History of a Temptation "is a history of the spice trade told not in the conventional narrative of politics and economics, nor of conquest and colonization, but through the intimate human impulses that inspired and drove it. Here is an exploration of the centuries-old desire for spice in food, in medicine, in magic, in religion, and in sex--and of the allure of forbidden fruit lingering in the scents of cinnamon, pepper, ginger, nutmeg, mace, and clove. We follow spices back through time, through history, myth, archaeology, and literature. We see spices in all their diversity, lauded as love potions and aphrodisiacs, as panaceas and defenses against the plague. We journey from religious rituals in which spices were employed to dispel demons and summon gods to prodigies of gluttony both fantastical and real. We see spices as a luxury for a medieval king's ostentation, as a mummy's deodorant, as the last word in haute cuisine. Through examining the temptations of spice we follow in the trails of the spice seekers leading from the deserts of ancient Syria to thrill-seekers on the Internet. We discover howspice became one of the first and most enduring links between Asia and Europe. We see in the pepper we use so casually the relic of a tradition linking us to the appetites of Rome, Elizabethan England, and the pharaohs. And we capture the pleasure of spice not only at the table but in every part of life. "Spice "is a delight to be savored.

    From Mary Lamb, sister of Charles, who in the throes of a nervous breakdown turned on her mother with a kitchen knife, to Freud, Jung, and Lacan, who developed the new women-centered therapies, Lisa Appignanesi’s research traces how more and more of the inner lives and emotions of women have become a matter for medics and therapists. Here too is the story of how over the years symptoms and diagnoses have developed together to create fashions in illness and how treatments have succeeded or sometimes failed. Mad, Bad, and Sad takes us on a fascinating journey through the fragile, extraordinary human mind.

    Days later, police discovered her remains in the surgery of the prominent anatomist Dr. Robert Knox. Docherty was the final victim of the most atrocious murder spree of the century, outflanking even Jack the Ripper's. Together with their accomplices, Burke and Hare would be accused of killing sixteen people over the course of twelve months in order to sell the corpses as "subjects" for dissection. The ensuing criminal investigation into the "Anatomy Murders" raised troubling questions about the common practices by which medical men obtained cadavers, the lives of the poor in Edinburgh's back alleys, and the ability of the police to protect the public from cold-blooded murder.Famous among true crime aficionados, Burke and Hare were the first serial killers to capture media attention, yet The Anatomy Murders is the first book to situate their story against the social and cultural forces that were bringing early nineteenth-century Britain into modernity. In Lisa Rosner's deft treatment, each of the murder victims, from the beautiful, doomed Mary Paterson to the unfortunate "Daft Jamie," opens a window on a different aspect of this world in transition. Tapping into a wealth of unpublished materials, Rosner meticulously portrays the aspirations of doctors and anatomists, the makeshift existence of the so-called dangerous classes, the rudimentary police apparatus, and the half-fiction, half-journalism of the popular press.The Anatomy Murders resurrects a tale of murder and medicine in a city whose grand Georgian squares and crescents stood beside a maze of slums, a place in which a dead body was far more valuable than a living laborer.

    She spent ten years training and working as an Anatomical Pathology Technologist: where the mortuary slab was her desk, and that day's corpses her task list.Past Mortems tells Carla's stories of those years, as well as investigating the body alongside our attitudes towards death - shedding light on what the living can learn from dead and the toll the work can take on the living souls who carry it out. Fascinating and insightful, Past Mortems reveals the truth about what happens when the mortuary doors swing shut or the lid of the coffin closes . . .

    A vital counter-interpretation of madness in women, showing how it is often a consequence of, rather than a deviation from, the traditional female role.

    Mass starvation, long predicted for the fast-growing population, was about to become a reality. A call went out to the world’s scientists to find a solution. This is the story of the two enormously gifted, fatally flawed men who found it: the brilliant, self-important Fritz Haber and the reclusive, alcoholic Carl Bosch. Together they discovered a way to make bread out of air, built city-sized factories, controlled world markets, and saved millions of lives. Their invention continues to feed us today; without it, more than two billion people would starve.But their epochal triumph came at a price we are still paying. The Haber-Bosch process was also used to make the gunpowder and high explosives that killed millions during the two world wars. Both men were vilified during their lives; both, disillusioned and disgraced, died tragically. Today we face the other un­intended consequences of their discovery—massive nitrogen pollution and a growing pandemic of obesity.The Alchemy of Air is the extraordinary, previously untold story of two master scientists who saved the world only to lose everything and of the unforseen results of a discovery that continues to shape our lives in the most fundamental and dramatic of ways.

    The Barbary Plague transports us to the Gold Rush boomtown in 1900, at the end of the city’s Gilded Age. With a deep understanding of the effects on public health of politics, race, and geography, Chase shows how one city triumphed over perhaps the most frightening and deadly of all scourges.

    Includes a chronological essay on death in America, as well as a bibliography.Sleeping Beauty is coveted for having played a large role in the rediscovery of the normalcy of postmortem photography. In 1990, Dr. Stanley B. Burns' landmark publication Sleeping Beauty, Memorial in Photography in America, ushered in a new era of appreciation of the importance of these images. Since the publication of Sleeping Beauty, exhibitions based on the 3-book series of memorial images have been created regularly. Perhaps the most prestigious was Le Dernier Portrait at Paris' Musée d'Orsay in 2002. To accompany the exhibit, Sleeping Beauty II: Grief, Bereavement and the Family, American & European Traditions was produced. In 2011, Sleeping Beauty III: Memorial Photography, The Children was written. Numerous other documentarians and feature filmmakers have utilized these poignant photographs, most notably in The Others. The Burns Archive serves as the premier source of images related to death, mourning and medial practices. Postmortem photography is the taking of a photograph of a deceased loved one, and was a normal part of American and European culture in the nineteenth and early twentieth centuries. It has nothing to do with images of violence, crime, or war. Death, and personally dealing with death, was prevalent throughout the entire world as epidemics would come quickly and kill quickly. Advances in medicine removed unexpected death from everyday life and professionals took over. Commissioned by grieving families, postmortem photographs not only helped in the grieving process, but often represented the only visual remembrance of the deceased and were among a family's most precious possessions. Mourning periods were based on family relationships and could last from months to years. Small photographs of the deceased were often carried in lockets or kept close to the body for greater intimacy. As many of the diseases that killed our ancestors were conquered and photography advanced during the century, society grew more and more distant from death, and practices, styles, and traditions of mourning and memorialization changed.The earliest postmortem photographs were often close-ups of the face or full body, at times depicted to appear lifelike or napping. Children were often positioned in a crib, posed with a favorite toy, or with a family member, most often the mother. Later photographs depict the subject in a coffin. Flowers, like forget-me-nots and calla lilies, were common in postmortem photography of all types. Later photographic memorials involve a shrine usually including a living portrait and flowers dedicated to the deceased.

    The year 2000 is alternatively the year 2544 (Buddhist), 6236 (Ancient Egyptian), 5761 (Jewish) or simply the Year of the Dragon (Chinese). The story of the creation of the Western calendar, which is related in this book, is a story of emperors and popes, mathematicians and monks, and the growth of scientific calculation to the point where, bizarrely, our measurement of time by atomic pulses is now more accurate than time itself: the Earth is an elderly lady and slightly eccentric - she loses half a second a century. Days have been invented (Julius Caesar needed an extra 80 days in 46BC), lost (Pope Gregory XIII ditched ten days in 1582) and moved (because Julius Caesar had 31 in his month, Augustus determined that he should have the same, so he pinched one from February).

    It was once notorious for the haunt of thieves, con-men, pimps, prostitutes and murderers, most notably Jack the Ripper. This publication chronicles the rise and fall of this remarkable street, from its promising beginnings in the 17th century as the centre of the silk weaving industry, through its gradual descent into iniquity, vice and violence to its final demise in the hands of the demolition men.

    On 29 March 1849, the ten-year-old Maharajah of the Punjab was ushered into the magnificent Mirrored Hall at the centre of the great Fort in Lahore. There, in a public ceremony, the frightened but dignified child handed over to the British East India Company in a formal Act of Submission to Queen Victoria not only swathes of the richest land in India, but also arguably the single most valuable object in the subcontinent: the celebrated Koh-i Noor diamond. The Mountain of Light. The history of the Koh-i-Noor that was then commissioned by the British may have been one woven together from gossip of Delhi Bazaars, but it was to be become the accepted version. Only now is it finally challenged, freeing the diamond from the fog of mythology which has clung to it for so long. The resulting history is one of greed, murder, torture, colonialism and appropriation through an impressive slice of south and central Asian history. It ends with the jewel in its current controversial setting: in the crown of Queen Elizabeth the Queen Mother. Masterly, powerful and erudite, this is history at its most compelling and invigorating.

    As the mosquito transformed the landscapes of civilization, humans were unwittingly required to respond to its piercing impact and universal projection of power.The mosquito has determined the fates of empires and nations, razed and crippled economies, and decided the outcome of pivotal wars, killing nearly half of humanity along the way. She (only females bite) has dispatched an estimated 52 billion people from a total of 108 billion throughout our relatively brief existence. As the greatest purveyor of extermination we have ever known, she has played a greater role in shaping our human story than any other living thing with which we share our global village.Imagine for a moment a world without deadly mosquitoes, or any mosquitoes, for that matter? Our history and the world we know, or think we know, would be completely unrecognizable.Driven by surprising insights and fast-paced storytelling, The Mosquito is the extraordinary untold story of the mosquito's reign through human history and her indelible impact on our modern world order.

    Poisons permeate our world. They are in the environment, the workplace, the home. They are in food, our favorite whiskey, medicine, well water. They have been used to cure disease as well as to incapacitate and kill. They smooth wrinkles, block pain, stimulate, and enhance athletic ability. In this entertaining and fact-filled book, science writer Peter Macinnis considers poisons in all their aspects. He recounts stories of the celebrated poisoners in history and literature, from Nero to Thomas Wainewright, and from the death of Socrates to Hamlet and Peter Pan. He discusses the sources of various poisons-from cyanide to strychnine, from Botox to ricin and Sarin gas-as well as their detection. Then he analyzes the science of their action in the body and their uses in medicine, cosmetics, war, and terrorism. With wit and precision, he weighs such questions as: Was Lincoln's volatility caused by mercury poisoning? Was Jack the Ripper an arsenic eater? Can wallpaper kill? For anyone who has ever wondered and been afraid to ask, here is a rich miscellany for your secret questions about toxins.