Worse, as they failed to cure her, they hinted that her devastating symptoms were psychological.The Lady's Handbook for Her Mysterious Illness is a memoir with a mission, to help the millions of (mostly) women who suffer from unnamed or misunderstood conditions.Ramey's pursuit of a diagnosis and cure for her own mysterious illness is a medical mystery that she says reveals a new understanding of today's chronic illnesses as ecological in nature, driven by modern changes to the basic foundations of health, from the quality of our sleep, diet, and social connection to the state of our microbiomes.

    The Gunfight at the O.K. Corral would shape how future generations came to view the Old West. Wyatt Earp, Doc Holliday, and the Clantons became the stuff of legends, symbolic of a frontier populated by good guys in white hats and villains in black ones. It's a colorful story--but the truth is even better. Drawing on new material from private collections--including diaries, letters, and Wyatt Earp's own hand-drawn sketch of the shootout's conclusion--as well as archival research, Jeff Guinn gives us a startlingly different and far more fascinating picture of what actually happened that day in Tombstone and why.

    He also harbored a terrifying secret: his attraction to men. As Strub explored the capital’s political and social circles, he discovered a parallel world where powerful men lived double lives shrouded in shame. When the AIDS epidemic hit in the early 1980s, Strub was living in New York and soon found himself attending “more funerals than birthday parties.” Scared and angry, he turned to radical activism to combat discrimination and demand research. Strub takes you through his own diagnosis and inside ACT UP, the organization that transformed a stigmatized cause into one of the defining political movements of our time. From the New York of Studio 54 and Andy Warhol’s Factory to the intersection of politics and burgeoning LGBT and AIDS movements, Strub’s story crackles with history. He recounts his role in shocking AIDS demonstrations at St. Patrick’s Cathedral as well as at the home of US Sen­ator Jesse Helms. With an astonishing cast of characters, including Tennessee Williams, Gore Vidal, Keith Haring, Bill Clinton, and Yoko Ono, this is a vivid portrait of a tumultuous era: “A page-turner…[with] the suspense and horror of Paul Monette’s memoir Borrowed Time and the drama of Larry Kramer’s play The Normal Heart….What a lot of action—and life—there is in this gripping book” (The Washington Post).

    She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

    Her famous Conversations changed women’s sense of how they could think and live; her editorship of the Transcendentalist literary journal The Dial shaped American Romanticism. Now, Megan Marshall, whose acclaimed The Peabody Sisters “discovered” three fascinating women, has done it again: no biography of Fuller has made her ideas so alive or her life so moving.Marshall tells the story of how Fuller, tired of Boston, accepted Horace Greeley’s offer to be the New York Tribune’s front-page columnist. The move unleashed a crusading concern for the urban poor and the plight of prostitutes, and a late-in-life hunger for passionate experience. In Italy as a foreign correspondent, Fuller took a secret lover, a young officer in the Roman Guard; she wrote dispatches on the brutal 1849 Siege of Rome; and she gave birth to a son.Yet, when all three died in a shipwreck off Fire Island shortly after Fuller’s 40th birthday, the sense and passion of her life’s work were eclipsed by tragedy and scandal. Marshall’s inspired account brings an American heroine back to indelible life.

    No Secret Service protection. No traveling press. Just Harry and his childhood sweetheart Bess, off to visit old friends, take in a Broadway play, celebrate their wedding anniversary in the Big Apple, and blow a bit of the money he’d just received to write his memoirs. Hopefully incognito. In this lively history, author Matthew Algeo meticulously details how Truman’s plan to blend in went wonderfully awry. Fellow diners, bellhops, cabbies, squealing teenagers at a Future Homemakers of America convention, and one very by-the-book Pennsylvania state trooper--all unknowingly conspired to blow his cover. Algeo revisits the Trumans’ route, staying at the same hotels and eating at the same diners, and takes readers on brief detours into topics such as the postwar American auto industry, McCarthyism, the nation’s highway system, and the decline of Main Street America. By the end of the 2,500-mile journey, you will have a new and heartfelt appreciation for America’s last citizen-president.

    In place of the domestic frump of popular imagination, Patricia Brady resurrects the wealthy, attractive, and vivacious young widow who captivated the youthful George Washington. Here are the able landowner, the indomitable patriot (who faithfully joined her husband each winter at Valley Forge), and the shrewd diplomat and emotional mainstay. And even as it brings Martha Washington into sharper and more accurate focus, this sterling life sheds light on her marriage, her society, and the precedents she established for future First Ladies.

    Peter Stark offers a harrowing saga in which a band of explorers battled nature, starvation, and madness to establish the first American settlement in the Pacific Northwest and opened up what would become the Oregon trail, permanently altering the nation's landscape and its global standing.Six years after Lewis and Clark began their journey to the Pacific Northwest, two of the Eastern establishment's leading figures, John Jacob Astor and Thomas Jefferson, turned their sights to founding a colony akin to Jamestown on the West Coast and transforming the nation into a Pacific trading power. Author and correspondent for Outside magazine Peter Stark recreates this pivotal moment in American history for the first time for modern readers, drawing on original source material to tell the amazing true story of the Astor Expedition.Unfolding over the course of three years, from 1810 to 1813, Astoria is a tale of high adventure and incredible hardship in the wilderness and at sea. Of the more than one hundred-forty members of the two advance parties that reached the West Coast—one crossing the Rockies, the other rounding Cape Horn—nearly half perished by violence. Others went mad. Within one year, the expedition successfully established Fort Astoria, a trading post on the Columbia River. Though the colony would be short-lived, it opened provincial American eyes to the potential of the Western coast and its founders helped blaze the Oregon Trail.

    The Ivy League institution dedicated to graduating “one thousand male leaders” each year had finally decided to open its doors to the nation’s top female students. The landmark decision was a huge step forward for women’s equality in education.Or was it?The experience the first undergraduate women found when they stepped onto Yale’s imposing campus was not the same one their male peers enjoyed. Isolated from one another, singled out as oddities and sexual objects, and barred from many of the privileges an elite education was supposed to offer, many of the first female students found themselves immersed in an overwhelmingly male culture they were unprepared to face. Yale Needs Women is the story of how these young women fought against the backward-leaning traditions of a centuries-old institution and created the opportunities that would carry them into the future. Anne Gardiner Perkins’s unflinching account of a group of young women striving for change is an inspiring story of strength, resilience, and courage that continues to resonate today.

    Army and Navy from small towns and elite colleges, more than ten thousand women served as codebreakers during World War II. While their brothers and boyfriends took up arms, these women moved to Washington and learned the meticulous work of code-breaking. Their efforts shortened the war, saved countless lives, and gave them access to careers previously denied to them. A strict vow of secrecy nearly erased their efforts from history; now, through dazzling research and interviews with surviving code girls, bestselling author Liza Mundy brings to life this riveting and vital story of American courage, service, and scientific accomplishment.

    Though he never left Italy, his inventions and discoveries were heralded around the world. Most sensationally, his telescopes allowed him to reveal a new reality in the heavens and to reinforce the astounding argument that the Earth moves around the Sun. For this belief, he was brought before the Holy Office of the Inquisition, accused of heresy, and forced to spend his last years under house arrest. Of Galileo's three illegitimate children, the eldest best mirrored his own brilliance, industry, and sensibility, and by virtue of these qualities became his confidante. Born Virginia in 1600, she was thirteen when Galileo placed her in a convent near him in Florence, where she took the most appropriate name of Suor Maria Celeste. Her loving support, which Galileo repaid in kind, proved to be her father's greatest source of strength throughout his most productive and tumultuous years. Her presence, through letters which Sobel has translated from their original Italian and masterfully woven into the narrative, graces her father's life now as it did then. Galileo's Daughter dramatically recolors the personality and accomplishment of a mythic figure whose seventeenth-century clash with Catholic doctrine continues to define the schism between science and religion. Moving between Galileo's grand public life and Maria Celeste's sequestered world, Sobel illuminates the Florence of the Medicis and the papal court in Rome during the pivotal era when humanity's perception of its place in the cosmos was being overturned. In that same time, while the bubonic plague wreaked its terrible devastation and the Thirty Years' War tipped fortunes across Europe, one man sought to reconcile the Heaven he revered as a good Catholic with the heavens he revealed through his telescope. With all the human drama and scientific adventure that distinguished Longitude, Galileo's Daughter is an unforgettable story.

    The popular image of the Regency continues to be mythologized by the hundreds of romance novels set in the period, which focus almost exclusively on wealthy, white, Christian members of the upper classes.But there are hundreds of fascinating women who don't fit history books limited perception of what was historically accurate for early 19th century England. Women like Dido Elizabeth Belle, whose mother was a slave but was raised by her white father's family in England, Caroline Herschel, who acted as her brother's assistant as he hunted the heavens for comets, and ended up discovering eight on her own, Anne Lister, who lived on her own terms with her common-law wife at Shibden Hall, and Judith Montefiore, a Jewish woman who wrote the first English language Kosher cookbook.As one of the owners of the successful romance-only bookstore The Ripped Bodice, Bea Koch has had a front row seat to controversies surrounding what is accepted as "historically accurate" for the wildly popular Regency period. Following in the popular footsteps of books like Ann Shen's Bad Girls Throughout History, Koch takes the Regency, one of the most loved and idealized historical time periods and a huge inspiration for American pop culture, and reveals the independent-minded, standard-breaking real historical women who lived life on their terms. She also examines broader questions of culture in chapters that focus on the LGBTQ and Jewish communities, the lives of women of color in the Regency, and women who broke barriers in fields like astronomy and paleontology. In Mad and Bad, we look beyond popular perception of the Regency into the even more vibrant, diverse, and fascinating historical truth.

    In a time when women could not vote, hold public office, or teach outside the home, the charismatic Hutchinson wielded remarkable political power. Her unconventional ideas had attracted a following of prominent citizens eager for social reform. Hutchinson defended herself brilliantly, but the judges, faced with a perceived threat to public order, banished her for behaving in a manner "not comely for [her] sex."Until now, Hutchinson has been a polarizing figure in American history and letters, attracting either disdain or exaltation. Nathaniel Hawthorne, who was haunted by the "sainted" Hutchinson, used her as a model for Hester Prynne in The Scarlet Letter. Much of the praise for her, however, is muted by a wish to domesticate the heroine: the bronze statue of Hutchinson at the Massachusetts State House depicts a prayerful mother -- eyes raised to heaven, a child at her side -- rather than a woman of power standing alone before humanity and God. Her detractors, starting with her neighbor John Winthrop, first governor of Massachusetts, referred to her as "the instrument of Satan," the new Eve, the "disturber of Israel," a witch, "more bold than a man," and Jezebel -- the ancient Israeli queen who, on account of her tremendous political power, was "the most evil woman" in the Bible.Written by one of Hutchinson's direct descendants, American Jezebel brings both balance and perspective to Hutchinson's story. It captures this American heroine's life in all its complexity, presenting her not as a religious fanatic, a cardboard feminist, or a raging crank-as some have portrayed her-but as a flesh-and-blood wife, mother, theologian, and political leader.Opening in a colonial courtroom, American Jezebel moves back in time to Hutchinson's childhood in Elizabethan England, exploring intimate details of her marriage and family life. The book narrates her dramatic expulsion from Massachusetts, after which her judges, still threatened by her challenges, promptly built Harvard College to enforce religious and social orthodoxies -- making her midwife to the nation's first college. In exile, she settled Rhode Island (which later merged with Roger Williams's Providence Plantation), becoming the only woman ever to co-found an American colony.The seeds of the American struggle for women's and human rights can be found in the story of this one woman's courageous life. American Jezebel illuminates the origins of our modern concepts of religious freedom, equal rights, and free speech, and showcases an extraordinary woman whose achievements are astonishing by the standards of any era.

    Run-down yet romantic, The Big House stands not only as a cherished reminder of summer’s ephemeral pleasures but also as a powerful symbol of a vanishing way of life.

    In Meg, Jo, Beth, Amy, Anne Boyd Rioux brings a fresh and engaging look at the circumstances leading Louisa May Alcott to write Little Women and why this beloved story of family and community ties set in the Civil War has resonated with audiences across time.