Although molecular topics are presented first, instructors can assign the chapters in any sequence. Pedagogical features such as chapter-opening “Key Questions” and strategically placed “Keynotes” help readers to efficiently master genetic concepts. The Genetics Place Companion Website contains interactive iActivities and narrated animations that help readers visualize and understand processes and concepts that are illustrated in the book. Genetics: An Introduction, DNA: The Genetic Material, DNA Replication, Gene Control of Proteins, Gene Expression: Transcription,Gene Expression: Translation, DNA Mutation, DNA Repair, and Transposable Elements, Structural Genomics, Functional and Comparative Genomics, Recombinant DNA Technology, Mendelian Genetics, Chromosomal Basis of Inheritance, Extensions of and Deviations from Mendelian Genetic Principles, Genetic Mapping in Eukaryotes, Genetics of Bacteria and Bacteriophages, Variations in Chromosome Structure and Number, Regulation of Gene Expression in Bacteria and Bacteriophages, Regulation of Gene Expression in Eukaryotes, Genetic Analysis of Development, Genetics of Cancer, Quantitative Genetics, Population Genetics, Molecular Evolution Intended for those interested in learning the basics of genetics

    In The Dance of Life, developmental and stem-cell biologist Magdalena Zernicka-Goetz takes us to the front lines of efforts to understand the creation of a human life. She has spent two decades unraveling the mysteries of development, as a simple fertilized egg becomes a complex human being of forty trillion cells. Zernicka-Goetz's work is both incredibly practical and astonishingly vast: her groundbreaking experiments with mouse, human, and artificial embryo models give hope to how more women can sustain viable pregnancies. Set at the intersection of science's greatest powers and humanity's greatest concern, The Dance of Life is a revelatory account of the future of fertility -- and life itself.

    Bird-eating snakes from Australia hitchhike to Hawaii in the landing gear of airliners; disruptive European zebra mussels, riding in ships' ballast water, are infiltrating aquatic ecosystems across the United States; parasitic flies from the U.S. prey on Darwin's finches in the Galapagos. Predatory American jellyfish in Russia; toxic Japanese plankton in Australia; Burmese pythons in the Everglades-biologists refer fearfully to "the homogenization of the world" as alien species jump from place to place and increasingly crowd native and endangered species out of existence. Never mind bulldozers and pesticides: the fastest-growing threat to biological diversity may be nature itself. "Out of Eden" is a journey through this strange and shifting landscape. The author tours the front lines of ecological invasion--in Hawaii, Tasmania, Guam, San Francisco; in lush rainforests, through underground lava tubes, on the deck of an Alaska-bound oil tanker--in the company of world-class scientists. Wry and reflective, animated and richly reported, "Out of Eden" is a search both for scientific answers and for ecological authenticity.

    People knew the basics: men and women had sex, and sometimes babies followed. But beyond that the origins of life were a colossal mystery. The Seeds of Life is the remarkable and rollicking story of how a series of blundering geniuses and brilliant amateurs struggled for two centuries to discover where, exactly, babies come from. Taking a page from investigative thrillers, acclaimed science writer Edward Dolnick looks to these early scientists as if they were detectives hot on the trail of a bedeviling and urgent mystery. These strange searchers included an Italian surgeon using shark teeth to prove that female reproductive organs were not 'failed' male genitalia, and a Catholic priest who designed ingenious miniature pants to prove that frogs required semen to fertilize their eggs. A witty and rousing history of science, The Seeds of Life presents our greatest scientists struggling-against their perceptions, their religious beliefs, and their deep-seated prejudices-to uncover how and where we come from.

    Beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in the sequencing of the Neanderthal genome in 2010, Neanderthal Man describes the events, intrigues, failures, and triumphs of these scientifically rich years through the lens of the pioneer and inventor of the field of ancient DNA.We learn that Neanderthal genes offer a unique window into the lives of our hominin relatives and may hold the key to unlocking the mystery of why humans survived while Neanderthals went extinct. Drawing on genetic and fossil clues, Pääbo explores what is known about the origin of modern humans and their relationship to the Neanderthals and describes the fierce debate surrounding the nature of the two species’ interactions. His findings have not only redrawn our family tree, but recast the fundamentals of human history—the biological beginnings of fully modern Homo sapiens, the direct ancestors of all people alive today.A riveting story about a visionary researcher and the nature of scientific inquiry, Neanderthal Man offers rich insight into the fundamental question of who we are.

    From the first microbes and jawless fishes that evolved into the myriad species we know today-sharks, whales, dolphins, and, of course, humans-Ellis reveals the deep evolutionary mysteries of the sea. Encyclopedic in scope and complemented by more than sixty drawings, Aquagenesis is a fascinating work that will astonish readers with the wonder, richness, and complexity of the evolution of life. "Quite simply, the best account we now have of the origins of human life." (Te Christian Science Monitor)

    The germ revolution came after two decades of scientific virtuosity, outstanding feats of intellectual courage and bitter personal rivalries, doctors at last recognised that infectious diseases are caused by mircoscopic organisms.

    News of both the Ice Man's discovery and his age, which was put at over five thousand years, fascinated scientists and newspapers throughout the world. But what made Sykes's story particularly revelatory was his successful identification of a genetic descendant of the Ice Man, a woman living in Great Britain today. How was Sykes able to locate a living relative of a man who died thousands of years ago?In The Seven Daughters of Eve, he gives us a firsthand account of his research into a remarkable gene, which passes undiluted from generation to generation through the maternal line. After plotting thousands of DNA sequences from all over the world, Sykes found that they clustered around a handful of distinct groups. Among Europeans and North American Caucasians, there are, in fact, only seven. This conclusion was staggering: almost everyone of native European descent, wherever they may live throughout the world, can trace their ancestry back to one of seven women, the Seven Daughters of Eve.Naming them Ursula, Xenia, Helena, Velda, Tara, Katrine, and Jasmine, Sykes has created portraits of their disparate worlds by mapping the migratory patterns followed by millions of their ancestors. In reading the stories of these seven women, we learn exactly how our origins can be traced, how and where our ancient genetic ancestors lived, and how we are each living proof of the almost indestructible strands of DNA, which have survived over so many thousands of years. Indeed, The Seven Daughters of Eve is filled with dramatic stories: from Sykes's identification, using DNA samples from two living relatives, of the remains of Tsar Nicholas and Tsaress Alexandra, to the Caribbean woman whose family had been sold into slavery centuries before and whose ancestry Sykes was able to trace back to the Eastern coast of central Africa. Ultimately, Sykes's investigation reveals that, as a race, what humans have in common is more deeply embedded than what separates us.

    Random genetic mutation, long believed to be the main source of variation, is only a marginal factor. As the authors demonstrate in this book, the more important source of speciation, by far, is the acquisition of new genomes by symbiotic merger. The result of thirty years of delving into a vast, mostly arcane literature, this is the first book to go beyond -- and reveal the severe limitations of -- the "Modern Synthesis" that has dominated evolutionary biology for almost three generations. Lynn Margulis, whom E. O. Wilson called "one of the most successful synthetic thinkers in modern biology," and her co-author Dorion Sagan have written a comprehensive and scientifically supported presentation of a theory that directly challenges the assumptions we hold about the variety of the living world.

    The story starts in earnest 3.8 billion years ago, with the earliest-known form of life on Earth, a bacteria that still exists today, and journeys through action-packed millennia, charting the appearance of new life forms as well as devastating extinction events. Of course, the ever-popular and endlessly intriguing dinosaurs feature large, but Prehistoric Life gives you the whole picture, and the plants, invertebrates, amphibians, birds, reptiles, and mammals that are the ancestors of today's species also populate its pages, making this book unprecedented in its coverage of prehistory. Specially commissioned artworks use cutting-edge technology to render species in breathtakingly realistic fashion, with astonishing images of prehistoric remains, such as skeletons and fossils, to complete the story. To put all the evidence in context, the concept of geological time is explored, as is the classification of species and how the evidence for their evolution is preserved and can be deciphered.New technologies have brought new life to inanimate fossils. CT scanning, for example, unlocks a 3D image of a plant or animal from a piece of rock, which can then be viewed from all angles revealing never-before-seen details. From this researchers can fill in missing pieces and even simulate how an animal might have moved. Panels explore these and numerous other scientific techniques for recovering, dating, and reconstructing, as well as profiling individuals, key excavations and discoveries, and some of the unique anatomical features that nature has developed over the course of time.The last section of the book looks at the development of humans and the eventual rise to dominance of Homo sapiens, exploring not only their changing anatomy as revealed by the fossils but also the evidence for culture and society as evidenced by extraordinary cave paintings and intricately worked tools.In combination, the stunning visuals, captivating, authoritative text, and comprehensive approach make Prehistoric Life a fascinating and revealing encyclopedia that will appeal to the whole family.TABLE OF CONTENTS1. LIVING PLANET (38 pp)Foundations of a living planet. The Earth's structure. Plate tectonics, formation of oceans and continents.Changing climate. factors that contribute to climate change, how those can be seen in the geological record, and how that has affected life on Earth.Reconstructing the past. Using the present to understand the past (rocks and the rock cycle, layers of rock and dating)Fossils. Types of fossils, how they form, reconstructing the past from them (digging up, analysis), reconstructing past environments, dating using fossils.Geological timescale. Explanation of geological time.Life on Earth. What is life? Natural selection, DNA, molecular clocks, mass extinctions.Timeline of Evolution. Broad-scale look at major evolutionary markers through time.Classification. How we classify living organisms. The kingdoms of life.2. ON EARTH (398 PP) This chapter will be organized so that pages can be removed to leave a section of 360pp.his consists of a catalog divided into geological periods. Each period introduction covers the conditions on Earth at the time (geology and climate) and includes a chart showing the evolution of the main forms of life. The subsequent catalog entries are organized into groups: Microscopic life; Plants and Fungi; Invertebrates; and Vertebrates, with each having an introduction detailing the main evolutionary developments within the group.Archean 3.8-2.5 billion years ago (4pp)Period introduction. (1p)Archean life intro - (1p) the rise of life. Biology of cells; prokaryotes, cyanobacteria, stromatolites.Catalog of species.Proterozoic 2.5 billion-543 mya (6pp)Period introduction. (2pp)Microscopic life intro. (1p)Catalog of species. (1p)Invertebrates intro. (1p)Catalog of species. (1p)Cambrian 543-490 mya (20pp)Period introduction (4pp)Microscopic life intro. (1p)Catalog of species. (3pp)Invertebrates intro. (2pp)Catalog of species. (8pp)Vertebrates intro. (1p)Catalog of species. (1p)Ordovician 490-443 mya (14pp)Period introduction. (4pp)Microscopic life intro. (1p)Catalog of species. (1p)Plants and fungi intro. (1p)Catalog of species.(1p)Invertebrates intro. (1p)Catalog of species. (3pp)Vertebrates intro. (1p)Catalog of species. (1p)Silurian 443-417 mya (20pp)Period introduction. (4pp)Microscopic life intro. (1p)Catalog of species. (1p)Plants and fungi intro. (1p)Catalog of species. (1p)Invertebrates intro. (1p)Catalog of species. (7pp)Vertebrates intro. (1p)Catalog of species. (3p)Devonian 417-354 mya (34pp)Period introduction. (4pp)Microscopic life intro. (1p)Catalog of species. (1p)Plants and fungi intro. (1p)Catalog of species. (7pp)Invertebrates intro. (1p)Catalog of species. (7pp)Vertebrates intro. (2p)Catalog of species. (10pp)Carboniferous 354-290 mya (38pp)Period introduction. (4pp)Microscopic life intro. (1p)Catalog of species. (1p)Plants and fungi intro. (2pp)Catalog of species. (8pp)Invertebrates intro. (1p)Catalog of species. (9pp)Vertebrates intro. (2pp)Catalog of species. (10pp)Permian 290-248 mya (26pp)Period introduction. (Microscopic life intro. (1p)Catalog of species. (1p)Plants and fungi intro. (1p)Catalog of species. (3pp)Invertebrates intro. (1p)Catalog of species. (7pp)Vertebrates intro. (1p)Catalog of species. (7pp)Triassic 248-206 mya (30pp)Period introduction. (Microscopic life intro. (1p)Catalog of species. (1p)Plants and fungi intro. (1p)Catalog of species. (5pp)Invertebrates intro. (1p)Catalog of species. (3pp)Vertebrates intro. (1pp)Catalog of species. (13pp)Jurassic 206-144 mya (56pp)Period introduction. (4pp)Microscopic life intro. (1p)Catalog of species. (1p)Plants and fungi intro. (1p)Catalog of species. (5pp)Invertebrates intro. (1p)Catalog of species. (9pp)Vertebrates intro. (2pp)Catalog of species. (24pp)Cretaceous 144-65 mya (54pp)Period introduction. (4pp)Microscopic life intro. (1p)Catalog of species. (1p)Plants and fungi intro. (2pp)Catalog of species. (10pp)Invertebrates intro. (1p)Catalog of species. (9pp)Vertebrates intro. (2pp)Catalog of species. (24pp)Paleogene 65-23.8 mya (34pp)Period introduction. (4pp)Microscopic life intro. (1p)Catalog of species. (1p)Plants and fungi intro. (1p)Catalog of species. (6pp)Invertebrates intro. (1p)Catalog of species. (6pp)Vertebrates intro. (2pp)Catalog of species. (12pp)Neogene 23.8-1.8 mya (32pp)Period introduction. (4pp)Microscopic life intro. (1p)Catalog of species. (1p)Plants and fungi intro. (1p)Catalog of species. (6pp)Invertebrates intro. (1p)Catalog of species. (7pp)Vertebrates intro. (1p)Catalog of species. (10pp)Quaternary 1.8 mya-Present (26pp)Period introduction. (4pp)Microscopic life intro. (1p)Catalog of species. (1p)Plants and fungi intro. (1p)Catalog of species. (Invertebrates intro. (1p)Catalog of species. (5pp)Vertebrates intro. (1p)Catalog of species. (8pp)3. THE RISE OF HUMANS (44PP)Timeline of human evolution.Coverage of: Sahelanthropus tchadensis, Orrorin tugenesis, Ardipithecus kadabba, Ardipithecus ramidus, Australopithecus anamensis, Australopithecus afarensis, Kenyanthropus platyops, Australopithecus africanus, Australopithecus aethiopicus, Australopithecus garhi, Homo habilis, Homo rudolfensis, Paranthropus boisei, Homo ergaster, Paranthropus robustus, Homo erectus, Homo heidelbergensis, Homo neanderthalensis, Homo sapiens.Themes of anatomy, DNA, global expansion, tool use, diet, communication, ecology, society, and culture run through the section.Glossary/Index/Acknowledgements

    The intriguing cast of characters includes Mary Anning, a working-class woman who became one of the most successful fossil collectors of all time; Thomas Hawkins, another amateur collector who "improved upon" fossils in order to increase their market value; the eccentric William Buckland, discoverer of the world's first dinosaur (Megalosaurus), and Richard Owen, an expert anatomist, who synthesized the discoveries of the age and ultimately coined the word "dinosaur" in 1842. Christopher McGowan takes us back to a time when the new sciences of geology and paleontology were as young and vibrant as genetic engineering is today. Through heated public debates on everything from the age of the earth to the notion of extinction, the Dragon Seekers initiated the shift from a biblical to a scientific interpretation of the remote past. In this way, they laid the intellectual groundwork for Darwin's revolutionary ideas, and launched a global obsession with the Age of Reptiles that continues even today.

    Every field, forest, and park is full of living organisms adapted for relationships with creatures that are now extinct. In a vivid narrative, Connie Barlow shows how the idea of "missing partners" in nature evolved from isolated, curious examples into an idea that is transforming how ecologists understand the entire flora and fauna of the Americas. This fascinating book will enrich and deepen the experience of anyone who enjoys a stroll through the woods or even down an urban sidewalk. But this knowledge has a dark side too: Barlow's "ghost stories" teach us that the ripples of biodiversity loss around us now are just the leading edge of what may well become perilous cascades of extinction.

    It stars turtles and shady and heroic human characters both, in settings ranging from luxury redoubts to degraded habitats, during a time when the confluence of easy global trade, limited supply, and inexhaustible demand has accelerated the stress on species. The growth of the middle class in high-population regions like China, where the turtle is particularly valued, feeds this perfect storm into which the turtle finds itself lashed. This is a tale not just of endangered turtles but also one of overall human failings, frailties, and vulnerabilities—all punctuated by optimistic hope for change fueled by dedicated turtle champions.

    After days of treatment for recurring infection, it becomes obvious that her arm must be amputated. Dr. Ajay Seth, the son of immigrant parents from India and a local orthopaedic surgeon in private practice, performs his first-ever amputation procedure. In the months that follow, divine intervention, combined with Melissa’s determination and Dr. Seth’s disciplined commitment and dedication to his patients, brings about the opportunity for a medical breakthrough that will potentially transform the lives of amputees around the world.Rewired is the inspirational, miraculous story of Dr. Seth’s revolutionary surgery that allows Melissa to not just move a prosthetic arm simply by thinking, but to actually feel with the prosthetic hand, just as she would with her natural arm. This resulted in what others have recognized as the world’s most advanced amputee, all done from Dr. Seth’s private practice in a community hospital, using a local staff, and with no special training or extensive research funding.

    Its presence in nature was dismissed as a desperate response to starvation or other life-threatening circumstances, and few spent time studying it. A taboo subject in our culture, the behavior was portrayed mostly through horror movies or tabloids sensationalizing the crimes of real-life flesh-eaters. But the true nature of cannibalism--the role it plays in evolution as well as human history--is even more intriguing (and more normal) than the misconceptions we've come to accept as fact. In Cannibalism: A Perfectly Natural History, zoologist Bill Schutt sets the record straight, debunking common myths and investigating our new understanding of cannibalism's role in biology, anthropology, and history in the most fascinating account yet written on this complex topic. Schutt takes readers from Arizona's Chiricahua Mountains, where he wades through ponds full of tadpoles devouring their siblings, to the Sierra Nevadas, where he joins researchers who are shedding new light on what happened to the Donner Party--the most infamous episode of cannibalism in American history. He even meets with an expert on the preparation and consumption of human placenta (and, yes, it goes well with Chianti). Bringing together the latest cutting-edge science, Schutt answers questions such as why some amphibians consume their mother's skin; why certain insects bite the heads off their partners after sex; why, up until the end of the twentieth century, Europeans regularly ate human body parts as medical curatives; and how cannibalism might be linked to the extinction of the Neanderthals. He takes us into the future as well, investigating whether, as climate change causes famine, disease, and overcrowding, we may see more outbreaks of cannibalism in many more species--including our own.Cannibalism places a perfectly natural occurrence into a vital new context and invites us to explore why it both enthralls and repels us.