Where are we? Who are we? Are our emotions, our beliefs, and our hopes and dreams ultimately meaningless out there in the void? Does human purpose and meaning fit into a scientific worldview?In short chapters filled with intriguing historical anecdotes, personal asides, and rigorous exposition, readers learn the difference between how the world works at the quantum level, the cosmic level, and the human level--and then how each connects to the other.  Carroll's presentation of the principles that have guided the scientific revolution from Darwin and Einstein to the origins of life, consciousness, and the universe is dazzlingly unique.Carroll shows how an avalanche of discoveries in the past few hundred years has changed our world and what really matters to us. Our lives are dwarfed like never before by the immensity of space and time, but they are redeemed by our capacity to comprehend it and give it meaning.The Big Picture is an unprecedented scientific worldview, a tour de force that will sit on shelves alongside the works of Stephen Hawking, Carl Sagan, Daniel Dennett, and E. O. Wilson for years to come.

    Our bodies are a quirky mix of new and old, with strokes of genius alongside glitches and imperfections which are all inherited from distant ancestors. Our development and evolutionary past explains why, as embryos, we have what look like gills, and as adults we suffer from back pain.This is a tale of discovery, not only exploring why and how we have developed as we have, but also looking at the history of our anatomical understanding. It combines the remarkable skills and qualifications Alice Roberts has as a doctor, anatomist, osteoarchaeologist and writer. Above all, she has a rare ability to make science accessible, relevant and interesting to mainstream audiences and readers.

    For every one of the cells that make up the vessel that you call your body, there are nine impostor cells hitching a ride. You are not just flesh and blood, muscle and bone, brain and skin, but also bacteria and fungi. Over your lifetime, you will carry the equivalent weight of five African elephants in microbes. You are not an individual but a colony.Until recently, we had thought our microbes hardly mattered, but science is revealing a different story, one in which microbes run our bodies and becoming a healthy human is impossible without them.In this riveting, shocking, and beautifully written book, biologist Alanna Collen draws on the latest scientific research to show how our personal colony of microbes influences our weight, our immune system, our mental health, and even our choice of partner. She argues that so many of our modern diseases—obesity, autism, mental illness, digestive disorders, allergies, autoimmunity afflictions, and even cancer—have their root in our failure to cherish our most fundamental and enduring relationship: that with our personal colony of microbes.Many of the questions about modern diseases left unanswered by the Human Genome Project are illuminated by this new science. And the good news is that unlike our human cells, we can change our microbes for the better. Collen's book is a revelatory and indispensable guide. It is science writing at its most relevant: life—and your body—will never seem the same again.

    With a foreword by New York Times bestselling author Dr. Joseph Mercola. Achieve more with less effort: The secret to weight loss, fitness, and wellness lies in the most basic and most overlooked function of your body—how you breathe. One of the biggest obstacles to better health and fitness is a rarely identified problem: chronic over-breathing. We often take many more breaths than we need—without realizing it—contributing to poor health and fitness, including a host of disorders, from anxiety and asthma to insomnia and heart problems. In The Oxygen Advantage, the man who has trained over 5,000 people—including Olympic and professional athletes—in reduced breathing exercises now shares his scientifically validated techniques to help you breathe more efficiently. Patrick McKeown teaches you the fundamental relationship between oxygen and the body, then gets you started with a Body Oxygen Level Test (BOLT) to determine how efficiently your body uses oxygen. He then shows you how to increase your BOLT score by using light breathing exercises and learning how to simulate high altitude training, a technique used by Navy SEALs and professional athletes to help increase endurance, weight loss, and vital red blood cells to dramatically improve cardio-fitness. Following his program, even the most out-of-shape person (including those with chronic respiratory conditions such as asthma) can climb stairs, run for a bus, or play soccer without gasping for air, and everyone can achieve: Easy weight loss and weight maintenance Improved sleep and energy Increased concentration Reduced breathlessness during exercise Heightened athletic performance Improved cardiovascular health Elimination of asthmatic symptoms, and more. With The Oxygen Advantage, you can look better, feel better, and do more—it's as easy as breathing.

    Millions have discovered the immense satisfaction to be found in growing something beautiful, in creating interesting combinations of plants, experimenting with new plants, and getting to know plants more intimately than they ever could with plants in the ground.Written by leading gardening journalist Bill Marken and the experts of the National Gardening Association, Container Gardening For Dummies is the ultimate guide to cultivating charming gardens in everything from a redwood window box to a hanging basket to an old pair of cowboy boots. It fills you in on how to:Grow almost anything in a container Make greens flourish on roofs, balconies, and windowsills Create a one-of-a-kind garden using classic and offbeat containers Use the best fertilizing and watering techniques for your climate Grow exotic and low-maintenance cacti and succulents Prevent insects, pests, and diseases from invading your containers Featuring clear, concise, step-by-step instructions and sixteen pages of stunning color photos, Container Gardening For Dummies covers all the bases, including:Opportunities and limitations of different climates Ready-made versus homemade soil mixes, starting plants from seeds, and other fundamentals Choosing, planting and caring for flowers, ferns, succulents, fruits, and vegetables Expressing your sense of style with color, form, texture, proportion, and other design elements Adding special effects to your container garden Container Gardening For Dummies is a fun, informative guide for inexperienced city slickers and savvy country cousins alike.

    If animals could talk, we would ask them to recall their own ancestries, in particular the secrets as to how they avoided almost inevitable annihilation in the face of daily assaults by predators, climactic cataclysms, deadly infections and innate diseases.In Tears of the Cheetah, medical geneticist and conservationist Stephen J. O'Brien narrates fast-moving science adventure stories that explore the mysteries of survival among the earth's most endangered and beloved wildlife. Here we uncover the secret histories of exotic species such as Indonesian orangutans, humpback whales, and the imperiled cheetah-the world's fastest animal which nonetheless cannot escape its own genetic weaknesses.Among these genetic detective stories we also discover how the Serengeti lions have lived with FIV (the feline version of HIV), where giant pandas really come from, how bold genetic action pulled the Florida panther from the edge of extinction, how the survivors of the medieval Black Death passed on a genetic gift to their descendents, and how mapping the genome of the domestic cat solved a murder case in Canada.With each riveting account of animal resilience and adaptation, a remarkable parallel in human medicine is drawn, adding yet another rationale for species conservation-mining their genomes for cures to our own fatal diseases. Tears of the Cheetah offers a fascinating glimpse of the insight gained when geneticists venutre into the wild.

    This book contains student-friendly Study Tips, Clinical View boxes, and progressive question sets to motivate students to internalize and apply what they've learned.

    You experience it passing every day when you watch clocks tick, bread toast, and children grow. But most physicists see things differently, from Newton to Einstein to today’s quantum theorists. For them, time isn’t real. You may think you experience time passing, but they say it’s just an illusion.Lee Smolin, author of the controversial bestseller The Trouble with Physics, argues this limited notion of time is holding physics back. It’s time for a major revolution in scientific thought. The reality of time could be the key to the next big breakthrough in theoretical physics.What if the laws of physics themselves were not timeless? What if they could evolve? Time Reborn offers a radical new approach to cosmology that embraces the reality of time and opens up a whole new universe of possibilties. There are few ideas that, like our notion of time, shape our thinking about literally everything, with major implications for physics and beyond—from climate change to the economic crisis. Smolin explains in lively and lucid prose how the true nature of time impacts our world.

    In that spirit, Edge.org publisher and author of Know This, John Brockman, asks 206 of the world’s most brilliant minds the 2017 Edge Question: What scientific term or concept ought to be more widely known?Contributors include: author of The God Delusion RICHARD DAWKINS on using animals’ “Genetic Book of the Dead” to reconstruct ecological history; MacArthur Fellow REBECCA NEWBERGER GOLDSTEIN on “scientific realism,” the idea that scientific theories explain phenomena beyond what we can see and touch; author of Seven Brief Lessons on Physics CARLO ROVELLI on “relative information,” which governs the physical world around us; theoretical physicist LAWRENCE M. KRAUSS on the hidden blessings of “uncertainty”; cognitive scientist and author of The Language Instinct STEVEN PINKER on “The Second Law of Thermodynamics”; biogerontologist AUBREY DE GREY on why “maladaptive traits” have been conserved evolutionarily; musician BRIAN ENO on “confirmation bias” in the internet age; Man Booker-winning author of Atonement IAN MCEWAN on the “Navier-Stokes Equations,” which govern everything from weather prediction to aircraft design and blood flow; plus pieces from RICHARD THALER, JARED DIAMOND, NICHOLAS CARR, JANNA LEVIN, LISA RANDALL, KEVIN KELLY, DANIEL COLEMAN, FRANK WILCZEK, RORY SUTHERLAND, NINA JABLONSKI, MARTIN REES, ALISON GOPNIK, and many, many others.

    Their discussion ranges from the history of the field's intellectual foundations to the most recent developments and applications.Reinforcement learning, one of the most active research areas in artificial intelligence, is a computational approach to learning whereby an agent tries to maximize the total amount of reward it receives when interacting with a complex, uncertain environment. In Reinforcement Learning, Richard Sutton and Andrew Barto provide a clear and simple account of the key ideas and algorithms of reinforcement learning. Their discussion ranges from the history of the field's intellectual foundations to the most recent developments and applications. The only necessary mathematical background is familiarity with elementary concepts of probability.The book is divided into three parts. Part I defines the reinforcement learning problem in terms of Markov decision processes. Part II provides basic solution methods: dynamic programming, Monte Carlo methods, and temporal-difference learning. Part III presents a unified view of the solution methods and incorporates artificial neural networks, eligibility traces, and planning; the two final chapters present case studies and consider the future of reinforcement learning.

    Keying Einstein's crucial discoveries to the simple mental images that inspired them, Michio Kaku finds a revealing new way to discuss his ideas, and delivers an appealing and always accessible introduction to Einstein's work.

    The most current information on the mechanisms, manifestations, and treatments of disease are clearly and concisely presented. Accessible writing, numerous illustrations in full-color, and complete and separate treatment of pediatric pathophysiology are the hallmarks of this popular and respected text. The new third edition features extensively revised and updated content and an enhanced art program.The book is divided into two parts. Part One presents the general principles of pathophysiology, including cell injury and repair; genetics; fluids and electrolytes, acids and bases; immunity, inflammation, and infection; stress; and cancer. Part Two is organized by body system, and for each system it covers normal anatomy and physiology, alterations of function in adults, and alterations of function in children.• Complete but concise coverage provides a thorough discussion of general pathophysiology and specific disease processes. • Outstanding full-color art program illustrates normal anatomy and physiology, disease processes, and clinical manifestations of disease. • Pediatric content is presented in 9 separate chapters to provide thorough coverage of how disease processes specifically affect children. • Health Alert boxes present brief discussions of new research, diagnostic studies, preventative care, treatments, or other developments related to health or specific diseases. • Quick Check questions appear at the end of major sections of text and are designed to promote critical thinking. Suggested answers to the questions are found on the CD companion included with the text. • Risk Factor boxes illustrate how certain risk factors are associated with specific diseases. • Did You Understand? chapter summaries provide students with a comprehensive review of the major concepts presented in each chapter. • Aging content is identified with a special icon within the adult chapters. • Algorithms are used throughout the text to illustrate normal and compensatory physiology and pathophysiology. • Key terms are boldface in text and listed with page numbers at the end of each chapter for easy reference and chapter review.• Approximately 250 new full-color drawings have been added. • An Introduction to Pathophysiology included in the front matter defines pathophysiology — and related terms such as etiology and epidemiology — and explains why it is important. • Extensive updates, based on the most current research, have been made throughout the book. • To reflect the latest developments, the Biology of Cancer chapter has been completely rewritten. • Several chapters, including Fluids and Electrolytes, Acids and Bases and Alterations of the Reproductive Systems have been extensively edited.

    But by itself, DNA is just an inert blueprint for life. It is the ribosome--an enormous molecular machine made up of a million atoms--that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. But this is also a human story of Ramakrishnan's unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the world's best scientists. In the end, Gene Machine is a frank insider's account of the pursuit of high-stakes science.

    . . . [He] takes us on a lively tour of engineers, their creations and their necessary turns of mind."   --Los Angeles TimesFrom the Ferris wheel to the integrated circuit, feats of engineering have changed our environment in countless ways, big and small. In Remaking the World: Adventures in Engineering, Duke University's Henry Petroski focuses on the big: Malaysia's 1,482-foot Petronas Towers as well as the Panama Canal, a cut through the continental divide that required the excavation of 311 million cubic yards of earth.        Remaking the World tells the stories behind the man-made wonders of the world, from squabbles over the naming of the Hoover Dam to the effects the Titanic disaster had on the engineering community of 1912. Here, too, are the stories of the personalities behind the wonders, from the jaunty Isambard Kingdom Brunel, designer of nineteenth-century transatlantic steamships, to Charles Steinmetz, oddball genius of the General Electric Company, whose office of preference was a battered twelve-foot canoe. Spirited and absorbing, Remaking the World is a celebration of the creative instinct and of the men and women whose inspirations have immeasurably improved our world."Petroski [is] America's poet laureate of technology. . . . Remaking the World is another fine book."   --Houston Chronicle"Remaking the World really is an adventure in engineering."--San Diego Union-Tribune

    Updated to reflect the latest research in the field, and enhanced with more than 1,000 illustrations, most in full-color, the 12th Edition is the most comprehensive and modern approach to understanding medical histology available anywhere.Features: NEW full-color micrographs that comprise a complete atlas of tissue sections highlight the important features of every tissue and organ in the human body. New full-color, easy-to-understand drawings provide just the right level of detail necessary to clarify the text and make learning easier A valuable introductory chapter on laboratory methods used for the study of tissues, including the most important types of microscopy A logical organization that features chapters focusing on the cytoplasmic and nuclear compartment of the cell, the four basic tissues that form the organs, and each organ system Expanded legends that accompany each figure emphasize important points and eliminate the need to jump from image to text Medical applications explain the clinical relevance of each topic Complete coverage of every tissue of the body CD-ROM with all the images from the textVisit www.LangeTextbooks.com to access valuable resources and study aids