Many books on the plague rely on statistics to tell the story: how many people died; how farm output and trade declined. But statistics can’t convey what it was like to sit in Siena or Avignon and hear that a thousand people a day are dying two towns away. Or to have to chose between your own life and your duty to a mortally ill child or spouse. Or to live in a society where the bonds of blood and sentiment and law have lost all meaning, where anyone can murder or rape or plunder anyone else without fear of consequence.In The Great Mortality, author John Kelly lends an air of immediacy and intimacy to his telling of the journey of the plague as it traveled from the steppes of Russia, across Europe, and into England, killing 75 million people—one third of the known population—before it vanished.

    The threat of the disease kept ships close to home and doomed those vessels that ventured too far from port. The willful ignorance of the royal medical elite, who endorsed ludicrous medical theories based on speculative research while ignoring the life-saving properties of citrus fruit, cost tens of thousands of lives and altered the course of many battles at sea. The cure for scurvy ranks among the greatest of human accomplishments, yet its impact on history has, until now, been largely ignored.From the earliest recorded appearance of the disease in the sixteenth century, to the eighteenth century, where a man had only half a chance of surviving the scourge, to the early nineteenth century, when the British conquered scurvy and successfully blockaded the French and defeated Napoleon, Scurvy is a medical detective story for the ages, the fascinating true story of how James Lind (the surgeon), James Cook (the mariner), and Gilbert Blane (the gentleman) worked separately to eliminate the dreaded affliction.Scurvy is an evocative journey back to the era of wooden ships and sails, when the disease infiltrated every aspect of seafaring life: press gangs "recruit" mariners on the way home from a late night at the pub; a terrible voyage in search of riches ends with a hobbled fleet and half the crew heaved overboard; Cook majestically travels the South Seas but suffers an unimaginable fate. Brimming with tales of ships, sailors, and baffling bureaucracy, Scurvy is a rare mix of compelling history and classic adventure story.

    Staff nursing in a ward where she's challenged by an inventory driven ward sister, she reckons it's time to swap such trivialities for life as a district nurse.Independent thinking is one thing, but Jane's about to find that the drama on district can demand instant reaction; and without hospital back up, she's usually the one having to provide it. She meets a rich cast of patients all determined to follow their own individual star, and goes to Edinburgh where Queen Victoria's Jubilee Institute's nurse training is considered the cr me de la cr me of the district nursing world.Call Me Sister recalls Jane's challenging and often hilarious route to realizing her own particular dream.

    Those selected for Bomber Command operations went on to rain devastation upon the Third Reich in the great air battles over Europe, but their losses were high. German fighters and anti-aircraft guns took a terrifying toll. The chances of surviving a tour of duty as a bomber crew were almost nil.Murray Peden's story of his training in Canada and England, and his crew's operations on Stirlings and Flying Fortresses with 214 Squadron, has been hailed as a classic of war literature. It is a fine blend of the excitement, humour, and tragedy of that eventful era.

    Journey is Robert and Suzanne Massie's memoir of raising their hemophiliac son in the 1950's, and the significant differences they found between the American and French healthcare systems.

    The authors offer evidence that the plane just simply ran out of fuel short of their Howland destination, and Earhart and Noonan were not captured by Japanese soldiers or islanders. The book covers the flying conditions under which Earhart flew - in an era before radar, with unreliable communications, grass landing strips and poorly mapped islands.

     Few people know much about stem cell research beyond the ethical questions raised by using embryos. But in the last decade, stem cell research has made huge advances toward eliminating some of our most intractable diseases. Now this sweeping and accessible book introduces us to this cutting-edge science that will revolutionize medicine and change the way we think about and treat disease. Alice Park takes us from stem cell's controversial beginnings to the recent electrifying promise of being able to create the versatile cells without using embryos at all. She shows us how stem cells give researchers an unprecedented ability to study disease while giving patients the promise of replacing diseased cells with healthy new ones. And she profiles the scientists and leaders-many with their own compelling stories-who have fueled the quest and will continue to shape the field in years to come.

    Otto’s subjects include the pioneering dentist who made Shirley Temple and Judy Garland’s teeth sparkle on the silver screen and helped create the all-American image of “pearly whites”; Deamonte Driver, the young Maryland boy whose tragic death from an abscessed tooth sparked congressional hearings; and a marketing guru who offers advice to dentists on how to push new and expensive treatments and how to keep Medicaid patients at bay.In one of its most disturbing findings, Teeth reveals that toothaches are not an occasional inconvenience, but rather a chronic reality for millions of people, including disproportionate numbers of the elderly and people of color. Many people, Otto reveals, resort to prayer to counteract the uniquely devastating effects of dental pain.Otto also goes back in time to understand the roots of our predicament in the history of dentistry, showing how it became separated from mainstream medicine, despite a century of growing evidence that oral health and general bodily health are closely related.Muckraking and paradigm-shifting, Teeth exposes for the first time the extent and meaning of our oral health crisis. It joins the small shelf of books that change the way we view society and ourselves—and will spark an urgent conversation about why our teeth matter.This is an alternate cover edition of ISBN 9781620971444.

    Now, in a tour-de-force narrative twenty years in the making, Ashton leads us on a journey through humanity’s greatest creations to uncover the surprising truth behind who creates and how they do it. From the crystallographer’s laboratory where the secrets of DNA were first revealed by a long forgotten woman, to the electromagnetic chamber where the stealth bomber was born on a twenty-five-cent bet, to the Ohio bicycle shop where the Wright brothers set out to “fly a horse,” Ashton showcases the seemingly unremarkable individuals, gradual steps, multiple failures, and countless ordinary and usually uncredited acts that lead to our most astounding breakthroughs.Creators, he shows, apply in particular ways the everyday, ordinary thinking of which we are all capable, taking thousands of small steps and working in an endless loop of problem and solution. He examines why innovators meet resistance and how they overcome it, why most organizations stifle creative people, and how the most creative organizations work. Drawing on examples from art, science, business, and invention, from Mozart to the Muppets, Archimedes to Apple, Kandinsky to a can of Coke, How to Fly a Horse is a passionate and immensely rewarding exploration of how “new” comes to be.

    Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings? A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.

    Within the course of a decade, tracks were being laid as far afield as Australia and Cuba, and by the outbreak of World War I, the United States alone boasted over a quarter of a million miles. With unrelenting determination, architectural innovation, and under gruesome labor conditions, a global railroad network was built that forever changed the way people lived. From Panama to Punjab, from Tasmania to Turin, Christian Wolmar shows how cultures were enriched, and destroyed, by one of the greatest global transport revolutions of our time, and celebrates the visionaries and laborers responsible for its creation.

    For the seventeenth-century aristocratic Frenchman, it meant changing his shirt once a day, using perfume to obliterate both his own aroma and everyone else’s, but never immersing himself in – horrors! – water. By the early 1900s, an extraordinary idea took hold in North America – that frequent bathing, perhaps even a daily bath, was advisable. Not since the Roman Empire had people been so clean, and standards became even more extreme as the millennium approached. Now we live in a deodorized world where germophobes shake hands with their elbows and where sales of hand sanitizers, wipes and sprays are skyrocketing.The apparently routine task of taking up soap and water (or not) is Katherine Ashenburg’s starting point for a unique exploration of Western culture, which yields surprising insights into our notions of privacy, health, individuality, religion and sexuality.Ashenburg searches for clean and dirty in plague-ridden streets, medieval steam baths, castles and tenements, and in bathrooms of every description. She reveals the bizarre rescriptions of history’s doctors as well as the hygienic peccadilloes of kings, mistresses, monks and ordinary citizens, and guides us through the twists and turns to our own understanding of clean, which is no more rational than the rest. Filled with amusing anecdotes and quotations from the great bathers of history, The Dirt on Clean takes us on a journey that is by turns intriguing, humorous, startling and not always for the squeamish. Ashenburg’s tour of history’s baths and bathrooms reveals much about our changing and most intimate selves – what we desire, what we ignore, what we fear, and a significant part of who we are.

    A teenage girl disappears on her way home from Coatesville High School. A reputed witch turns up dead in Pottsville. A young woman seemingly helps solve her own murder after she dies in a Philadelphia park.True-crime author Tammy Mal digs up facts on four of Pennsylvania’s weirdest killings in her book Tortured Minds: Pennsylvania’s Most Bizarre—But Forgotten—Murders. These 1930s crimes have long fallen into obscurity, but Mal deftly revives them in stark detail, from discovery of the body and through the trial. Ghosts, witches, resentment, and sex factor into these crimes, giving them a chilling edge as Mal brings them back to life in her latest true-crime book. It’s a look into just what tortured minds can do, certain to convince you to lock your doors after dark.

    But until now, we have known only half the story. With the end of the cold war, decades of secrets have been exposed, bringing with them a remarkable opportunity: the unmasking of the true heroes and villains behind one of the most exciting races in history.At the center of this exhilarating, fast-paced account are Wernher von Braun, the camera-friendly former Nazi scientist who led the American rocket design team, and Sergei Korolev, the chief Soviet designer and former political prisoner whose identity was a closely guarded state secret. These rivals were opposite in every way, save for one: each was obsessed by the idea of launching a man to the Moon. Korolev told his wife, "In every century men were looking into the sky and dreaming. And now I'm close to the greatest dream of mankind."In attempting to fulfill this dream, Korolev was initially hampered by a budget so small that his engineers were forced to repurpose cardboard boxes as drafting tables. Von Braun, meanwhile, was eventually granted almost limitless access to funds by an American government panicked at the thought that their cold war enemy might take the lead in the exploration of space. Korolev, whose family life was destroyed by his long sentence in the Gulag, was constantly aware that any false move would finish his career or even his life. His rival, on the other hand, enjoyed remarkable celebrity in America and was even the subject of a 1960 biopic.In this extraordinary book, Deborah Cadbury combines sheeradventure and nail-biting suspense with a moving portrayal of the space race's human dimension. Using source materials never before seen, she reveals that the essential story of the cold war is a mind-bending voyage beyond the bounds of the Earth, one marked by espionage, ambition, ingenuity, and passion.

    Martin as source material for Game of Thrones, comes a classic book on innovation and technological change in medieval EuropeIn this account of Europe’s rise to world leadership in technology, Frances and Joseph Gies show how early modern technology and experimental science were direct outgrowths of the decisive innovations of medieval Europe, in the tools and techniques of agriculture, craft industry, metallurgy, building construction, navigation, and war. The Gieses report that many of Europe’s most important inventions—the horse harness, the stirrup, the magnetic compass, cotton and silk cultivation and manufacture, papermaking, firearms, and “Arabic” numerals—had their origins outside Europe, in China, India, and the Middle East. Europe synthesized its own innovations—the three-field system, water power in industry, the full-rigged ship, the putting-out system—into a powerful new combination of technology, economics, and politics.