She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

    You mean I peaked in December of 1963?I’m afraid so.But he never quit trying to impress her. In his writing, she was sometimes his subject and always his muse. The dedication of the first book he published after her death read, “I wrote this for Alice. Actually, I wrote everything for Alice.”In that spirit, Calvin Trillin has, with About Alice, created a gift to the wife he adored and to his readers.

    Michael Perry loves this place. He grew up here, and now -- after a decade away -- he has returned. Unable to polka or repair his own pickup, his farm-boy hands gone soft after years of writing, Mike figures the best way to regain his credibility is to join the volunteer fire department. Against a backdrop of fires and tangled wrecks, bar fights and smelt feeds, he tells a frequently comic tale leavened with moments of heartbreaking delicacy and searing tragedy.

    One day he was a doctor treating the dying, and the next he was a patient struggling to live. And just like that, the future he and his wife had imagined evaporated. When Breath Becomes Air chronicles Kalanithi's transformation from a naïve medical student "possessed," as he wrote, "by the question of what, given that all organisms die, makes a virtuous and meaningful life" into a neurosurgeon at Stanford working in the brain, the most critical place for human identity, and finally into a patient and new father confronting his own mortality. What makes life worth living in the face of death? What do you do when the future, no longer a ladder toward your goals in life, flattens out into a perpetual present? What does it mean to have a child, to nurture a new life as another fades away? These are some of the questions Kalanithi wrestles with in this profoundly moving, exquisitely observed memoir. Paul Kalanithi died in March 2015, while working on this book, yet his words live on as a guide and a gift to us all. "I began to realize that coming face to face with my own mortality, in a sense, had changed nothing and everything," he wrote. "Seven words from Samuel Beckett began to repeat in my head: 'I can't go on. I'll go on.'" When Breath Becomes Air is an unforgettable, life-affirming reflection on the challenge of facing death and on the relationship between doctor and patient, from a brilliant writer who became both.

    You will be born in New Mexico. You will get your big break at an acting camp. You will get into a bizarre confrontation outside a nightclub with actor Scott Caan. Even better, at each critical juncture of your life, you will choose how to proceed. You will decide whether to try out for Doogie Howser, M.D. You will decide whether to spend years struggling with your sexuality. You will decide what kind of caviar you want to eat on board Elton John’s yacht. Choose correctly and you’ll find fame, fortune, and true love. Choose incorrectly and you’ll find misery, heartbreak, and a hideous death by piranhas. All this, plus magic tricks, cocktail recipes, embarrassing pictures from your time as a child actor, and even a closing song. Yes, if you buy one book this year, congratulations on being above the American average, but make that book Neil Patrick Harris: Choose Your Own Autobiography!

    Now I’m letting my guard down.” —Hillary Rodham Clinton, from the introduction of What HappenedFor the first time, Hillary Rodham Clinton reveals what she was thinking and feeling during one of the most controversial and unpredictable presidential elections in history. Now free from the constraints of running, Hillary takes you inside the intense personal experience of becoming the first woman nominated for president by a major party in an election marked by rage, sexism, exhilarating highs and infuriating lows, stranger-than-fiction twists, Russian interference, and an opponent who broke all the rules. This is her most personal memoir yet. In these pages, she describes what it was like to run against Donald Trump, the mistakes she made, how she has coped with a shocking and devastating loss, and how she found the strength to pick herself back up afterward. With humor and candor, she tells readers what it took to get back on her feet—the rituals, relationships, and reading that got her through, and what the experience has taught her about life. She speaks about the challenges of being a strong woman in the public eye, the criticism over her voice, age, and appearance, and the double standard confronting women in politics. She lays out how the 2016 election was marked by an unprecedented assault on our democracy by a foreign adversary. By analyzing the evidence and connecting the dots, Hillary shows just how dangerous the forces are that shaped the outcome, and why Americans need to understand them to protect our values and our democracy in the future. The election of 2016 was unprecedented and historic. What Happened is the story of that campaign and its aftermath—both a deeply intimate account and a cautionary tale for the nation.

    There were always little reminders pasted on the kitchen wall. For example, the word THINK. I found THINK thumbtacked on a bulletin board in her darkroom. I saw it Scotch-taped on a pencil box she’d collaged. I even found a pamphlet titled THINK on her bedside table. Mom liked to THINK. So begins Diane Keaton’s unforgettable memoir about her mother and herself. In it you will meet the woman known to tens of millions as Annie Hall, but you will also meet, and fall in love with, her mother, the loving, complicated, always-thinking Dorothy Hall. To write about herself, Diane realized she had to write about her mother, too, and how their bond came to define both their lives. In a remarkable act of creation, Diane not only reveals herself to us, she also lets us meet in intimate detail her mother. Over the course of her life, Dorothy kept eighty-five journals—literally thousands of pages—in which she wrote about her marriage, her children, and, most probingly, herself. Dorothy also recorded memorable stories about Diane’s grandparents. Diane has sorted through these pages to paint an unflinching portrait of her mother—a woman restless with intellectual and creative energy, struggling to find an outlet for her talents—as well as her entire family, recounting a story that spans four generations and nearly a hundred years. More than the autobiography of a legendary actress, Then Again is a book about a very American family with very American dreams. Diane will remind you of yourself, and her bonds with her family will remind you of your own relationships with those you love the most.

    When Carrie Fisher discovered the journals she kept during the filming of the first Star Wars movie, she was astonished to see what they had preserved--plaintive love poems, unbridled musings with youthful naiveté, and a vulnerability that she barely recognized. Before her passing, her fame as an author, actress, and pop-culture icon was indisputable, but in 1977, Carrie Fisher was just a teenager with an all-consuming crush on her costar, Harrison Ford.With these excerpts from her handwritten notebooks, The Princess Diarist is Fisher's intimate and revealing recollection of what happened on one of the most famous film sets of all time--and what developed behind the scenes. Fisher also ponders the joys and insanity of celebrity, and the absurdity of a life spawned by Hollywood royalty, only to be surpassed by her own outer-space royalty. Laugh-out-loud hilarious and endlessly quotable, The Princess Diarist brims with the candor and introspection of a diary while offering shrewd insight into one of Hollywood's most beloved stars.

    It is the story of how one woman learned that a responsible mother is not one who slowly dies for her children, but one who shows them how to fully live. It is the story of navigating divorce, forming a new blended family, and discovering that the brokenness or wholeness of a family depends not on its structure but on each member’s ability to bring her full self to the table. And it is the story of how each of us can begin to trust ourselves enough to set boundaries, make peace with our bodies, honor our anger and heartbreak, and unleash our truest, wildest instincts so that we become women who can finally look at ourselves and say: There She Is.

    Howe, an editor at the rarefied Paris Review, agrees to go along. Things soon become a lot more complicated. After the business struggles, Howe finds himself living in the basement of his in-laws' Staten Island home, commuting to the Paris Review offices in George Plimpton's Upper East Side townhouse by day, and heading to Brooklyn at night to slice cold cuts and peddle lottery tickets. My Korean Deli follows the store's tumultuous life span, and along the way paints the portrait of an extremely unlikely partnership between characters with shoots across society, from the Brooklyn streets to Seoul to Puritan New England. Owning the deli becomes a transformative experience for everyone involved as they struggle to salvage the original gift--and the family--while sorting out issues of values, work, and identity.

    The last thing Gwen Cooper wanted was another cat. She already had two, not to mention a phenomenally underpaying job and a recently broken heart. Then Gwen’s veterinarian called with a story about a three-week-old eyeless kitten who’d been abandoned. It was love at first sight.Everyone warned that Homer would always be an "underachiever," never as playful or independent as other cats. But the kitten nobody believed in quickly grew into a three-pound dynamo, a tiny daredevil with a giant heart who eagerly made friends with every human who crossed his path. Homer scaled seven-foot bookcases with ease and leapt five feet into the air to catch flies in mid-buzz. He survived being trapped alone for days after 9/11 in an apartment near the World Trade Center, and even saved Gwen’s life when he chased off an intruder who broke into their home in the middle of the night.But it was Homer’s unswerving loyalty, his infinite capacity for love, and his joy in the face of all obstacles that inspired Gwen daily and transformed her life. And by the time she met the man she would marry, she realized Homer had taught her the most important lesson of all: Love isn’t something you see with your eyes.Homer’s Odyssey is the once-in-a-lifetime story of an extraordinary cat and his human companion. It celebrates the refusal to accept limits—on love, ability, or hope against overwhelming odds. By turns jubilant and moving, it’s a memoir for anybody who’s ever fallen completely and helplessly in love with a pet.

    Raised up from poverty by a determined single mother, the gifted and beautiful twins were able to create a private haven of splendor and merriment between themselves and then earn their way to a prestigious college and to careers as artists (a photographer and a writer, respectively) and to young marriages. But, haunted by childhood experiences with father figures and further damaged by being raped as a young adult, Cara veered off the path to robust work and life and in to depression, drugs and a shocking early death.A few years after Cara was gone, Christa read that when an identical twin dies, regardless of the cause, 50 percent of the time the surviving twin dies within two years; and this shocking statistic rang true to her. "Flip a coin," she thought," those were my chances of survival." First, Christa fought to stop her sister's downward spiral; suddenly, she was struggling to keep herself alive.Beautifully written, mesmerizingly rich and true, Christa Parravani's account of being left, one half of a whole, and of her desperate, ultimately triumphant struggle for survival is informative, heart-wrenching and unforgettably beautiful.Wall Street Journal, "Favorite Books of the Year 2013"Cosmopolitan, "Best Books of the Year for Women"Library Journal, "Best Books of 2013"Salon, "Best Books of 2013"

    Decades later she found her old diaries in a storage bin, and hoped to discover the early evidence of the person (and writer) she’d since become. Instead, “The actual diaries revealed me to possess the mind of a paranoid tax auditor.”     Thus was born a desire to try again, to chronicle her daily life as a fortysomething woman, wife, mother, and writer. The dazzling result is The Folded Clock, in which the diary form becomes a meditation on time and self, youth and aging, betrayal and loyalty, friendship and romance, faith and fate, marriage and family, desire and death, gossip and secrets, art and ambition.     The Folded Clock is as playful as it is brilliant, a tour de force by one of the most gifted prose stylists in American letters.

    To protect himself and those he loved from street violence, Andre learned to use his fists so well that he was even scared of himself. He was on a fast track to getting killed - or killing someone else. He signed on as a boxer. Nearby, his father, an eminent author, taught on a college campus and took the kids out on Sundays. The clash of worlds couldn't have been more stark - or more difficult for a son to communicate to a father. Only by becoming a writer himself could Andre begin to bridge the abyss and save himself. His memoir is a riveting, visceral, profound meditation on physical violence and the failures and triumphs of love.

    Ryan and his friend, miniature schnauzer Atticus M. Finch, would attempt to climb all forty-eight of New Hampshire’s four-thousand-foot peaks twice in one winter while raising money for charity. It was an adventure of a lifetime, leading them across hundreds of miles and deep into an enchanting but dangerous winter wonderland. At the heart of the amazing journey was the extraordinary relationship they shared, one that blurred the line between man and dog.Following Atticus is an unforgettable true saga of adventure, friendship, and the unlikeliest of family, as one remarkable animal opens the eyes and heart of a tough-as-nails newspaperman to the world’s beauty and its possibilities