There he meets David Smith, a medical student recovering from drug addiction, and the two men begin a tennis ritual that allows them to shed their inhibitions and find security in the sport they love and with each other. This friendship between doctor and intern grows increasingly rich and complex, more intimate than two men usually allow. Just when it seems nothing can go wrong, the dark beast from David’s past emerges once again—and almost everything Verghese has come to trust and believe in is threatened as David spirals out of control.

    An inspiring firsthand account of a courageous and determined autistic woman who makes a remarkable discovery that eventually helps her control her condition and virtually cure her disorder captures the isolation and fears suffered by autistic children.

    But which one? And how?Over the past fifty years, more than three hundred infectious diseases have either newly emerged or reemerged, appearing in territories where they’ve never been seen before. Ninety percent of epidemiologists expect that one of them will cause a deadly pandemic sometime in the next two generations. It could be Ebola, avian flu, a drug-resistant superbug, or something completely new. While we can’t know which pathogen will cause the next pandemic, by unraveling the story of how pathogens have caused pandemics in the past, we can make predictions about the future. In Pandemic: Tracking Contagions, from Cholera to Ebola and Beyond, the prizewinning journalist Sonia Shah—whose book on malaria, The Fever, was called a “tour-de-force history” (The New York Times) and “revelatory” (The New Republic)—interweaves history, original reportage, and personal narrative to explore the origins of contagions, drawing parallels between cholera, one of history’s most deadly and disruptive pandemic-causing pathogens, and the new diseases that stalk humankind today.To reveal how a new pandemic might develop, Sonia Shah tracks each stage of cholera’s dramatic journey, from its emergence in the South Asian hinterlands as a harmless microbe to its rapid dispersal across the nineteenth-century world, all the way to its latest beachhead in Haiti. Along the way she reports on the pathogens now following in cholera’s footsteps, from the MRSA bacterium that besieges her own family to the never-before-seen killers coming out of China’s wet markets, the surgical wards of New Delhi, and the suburban backyards of the East Coast.By delving into the convoluted science, strange politics, and checkered history of one of the world’s deadliest diseases, Pandemic reveals what the next global contagion might look like— and what we can do to prevent it.

    Overnight, these women were transformed from military spouses into American royalty. They had tea with Jackie Kennedy, appeared on the cover of Life magazine, and quickly grew into fashion icons.Annie Glenn, with her picture-perfect marriage, was the envy of the other wives; JFK made it clear that platinum-blonde Rene Carpenter was his favorite; and licensed pilot Trudy Cooper arrived with a secret that needed to stay hidden from NASA. Together with the other wives they formed the Astronaut Wives Club, providing one another with support and friendship, coffee and cocktails.As their celebrity rose-and as divorce and tragedy began to touch their lives-the wives continued to rally together, forming bonds that would withstand the test of time, and they have stayed friends for over half a century. THE ASTRONAUT WIVES CLUB tells the story of the women who stood beside some of the biggest heroes in American history.

    Learning all the tongue twisting names, picking favorites based on ferocity, armor, or sheer size. For many kids this love of ‘terrible lizards’ fizzles out at some point between starting and leaving primary school. All those fancy names slowly forgotten, no longer any need for a favorite.For all those child dino fanatics who didn’t grow up to become paleontologists, dinosaurs seem like something out of mythology. They are dragons, pictures in books, abstract, other, extinct.They are at the same time familiar and mysterious. And yet we’re in an age of rapid discovery—new dinosaur species and genera are being discovered at an accelerating rate, we’re learning more about what they looked like, how they lived, how they evolved and where they all went.This series isn’t just a top trumps list of dino facts—we’re interested in the why and the how and like all areas of science there is plenty of controversy and debate.

    His job no longer existed. "I think they just want to hire younger people," his boss at Newsweek told him. Fifty years old and with a wife and two young kids, Dan was, in a word, screwed. Then an idea hit. Dan had long reported on Silicon Valley and the tech explosion. Why not join it? HubSpot, a Boston start-up, was flush with $100 million in venture capital. They offered Dan a pile of stock options for the vague role of "marketing fellow." What could go wrong? HubSpotters were true believers: They were making the world a better place ... by selling email spam. The office vibe was frat house meets cult compound: The party began at four thirty on Friday and lasted well into the night; "shower pods" became hook-up dens; a push-up club met at noon in the lobby, while nearby, in the "content factory," Nerf gun fights raged. Groups went on "walking meetings," and Dan's absentee boss sent cryptic emails about employees who had "graduated" (read: been fired). In the middle of all this was Dan, exactly twice the age of the average HubSpot employee, and literally old enough to be the father of most of his co-workers, sitting at his desk on his bouncy-ball "chair."Mixed in with Lyons's uproarious tale of his rise and fall at Hubspot is a trenchant analysis of the start-up world, a de facto conspiracy between those who start companies and those who fund them, a world where bad ideas are rewarded with hefty investments, where companies blow money lavishing perks on their post-collegiate workforces, and where everybody is trying to hang on just long enough to reach an IPO and cash out. With a cast of characters that includes devilish angel investors, fad-chasing venture capitalists, entrepreneurs and "wantrapreneurs," bloggers and brogrammers, social climbers and sociopaths, Disrupted is a gripping and definitive account of life in the (second) tech bubble.

    We know that accidents happen, but we believe we are on earth for a reason. Until now, most scientists have argued that science and faith occupy distinct arenas. Francis Collins, a former atheist as a science student who converted to faith as he became a doctor, is about to change that. Collins's faith in God has been confirmed and enhanced by the revolutionary discoveries in biology that he has helped to oversee. He has absorbed the arguments for atheism of many scientists and pundits, and he can refute them. Darwinian evolution occurs, yet, as he explains, it cannot fully explain human nature - evolution can and must be directed by God. He offers an inspiring tour of the human genome to show the miraculous nature of God's instruction book.

    This book gives details of their research and investigations into the use of psychedelic drugs for the study of the human mind, and is also a love story. The second half of the book describes in detail a wealth of phenethlyamines, their physical properties, dosages used, duration of effects observed, and commentary on effects.

    Drawing on the diaries of a midwife and healer in eighteenth-century Maine, this intimate history illuminates the medical practices, household economies, religious rivalries, and sexual mores of the New England frontier.

    Part intellectual journey, part memoir, Hamlet's BlackBerry sets out to solve what William Powers calls the conundrum of connectedness. Our computers and mobile devices do wonderful things for us. But they also impose an enormous burden, making it harder for us to focus, do our best work, build strong relationships, and find the depth and fulfillment we crave.Hamlet's BlackBerry argues that we need a new way of thinking, an everyday philosophy for life with screens. To find it, Powers reaches into the past, uncovering a rich trove of ideas that have helped people manage and enjoy their connected lives for thousands of years. New technologies have always brought the mix of excitement and stress that we feel today. Drawing on some of history's most brilliant thinkers, from Plato to Shakespeare to Thoreau, he shows that digital connectedness serves us best when it's balanced by its opposite, disconnectedness.Using his own life as laboratory and object lesson, Powers demonstrates why this is the moment to revisit our relationship to screens and mobile technologies, and how profound the rewards of doing so can be. Lively, original, and entertaining, Hamlet's BlackBerry will challenge you to rethink your digital life.

    From New England aquarium tanks to the reefs of French Polynesia and the Gulf of Mexico, she has befriended octopuses with strikingly different personalities—gentle Athena, assertive Octavia, curious Kali, and joyful Karma. Each creature shows her cleverness in myriad ways: escaping enclosures like an orangutan; jetting water to bounce balls; and endlessly tricking companions with multiple “sleights of hand” to get food.Scientists have only recently accepted the intelligence of dogs, birds, and chimpanzees but now are watching octopuses solve problems and are trying to decipher the meaning of the animal’s color-changing techniques. With her “joyful passion for these intelligent and fascinating creatures” (Library Journal Editors’ Spring Pick), Montgomery chronicles the growing appreciation of this mollusk as she tells a unique love story. By turns funny, entertaining, touching, and profound, The Soul of an Octopus reveals what octopuses can teach us about the meeting of two very different minds.

    The tiger isn’t just killing people, it’s annihilating them, and a team of men and their dogs must hunt it on foot through the forest in the brutal cold. As the trackers sift through the gruesome remains of the victims, they discover that these attacks aren’t random: the tiger is apparently engaged in a vendetta. Injured, starving, and extremely dangerous, the tiger must be found before it strikes again.As he re-creates these extraordinary events, John Vaillant gives us an unforgettable portrait of this spectacularly beautiful and mysterious region. We meet the native tribes who for centuries have worshipped and lived alongside tigers, even sharing their kills with them. We witness the arrival of Russian settlers in the nineteenth and early twentieth centuries, soldiers and hunters who greatly diminished the tiger populations. And we come to know their descendants, who, crushed by poverty, have turned to poaching and further upset the natural balance of the region.This ancient, tenuous relationship between man and predator is at the very heart of this remarkable book. Throughout we encounter surprising theories of how humans and tigers may have evolved to coexist, how we may have developed as scavengers rather than hunters, and how early Homo sapiens may have fit seamlessly into the tiger’s ecosystem. Above all, we come to understand the endangered Siberian tiger, a highly intelligent super-predator that can grow to ten feet long, weigh more than six hundred pounds, and range daily over vast territories of forest and mountain.Beautifully written and deeply informative, The Tiger circles around three main characters: Vladimir Markov, a poacher killed by the tiger; Yuri Trush, the lead tracker; and the tiger himself. It is an absolutely gripping tale of man and nature that leads inexorably to a final showdown in a clearing deep in the taiga.

     A riveting, powerful telling of the story of the grassroots movement of activists, many of them in a life-or-death struggle, who seized upon scientific research to help develop the drugs that turned HIV from a mostly fatal infection to a manageable disease. Ignored by public officials, religious leaders, and the nation at large, and confronted with shame and hatred, this small group of men and women chose to fight for their right to live by educating themselves and demanding to become full partners in the race for effective treatments. Around the globe, 16 million people are alive today thanks to their efforts. Not since the publication of Randy Shilts's classic And the Band Played On has a book measured the AIDS plague in such brutally human, intimate, and soaring terms. In dramatic fashion, we witness the founding of ACT UP and TAG (Treatment Action Group), and the rise of an underground drug market in opposition to the prohibitively expensive (and sometimes toxic) AZT. We watch as these activists learn to become their own researchers, lobbyists, drug smugglers, and clinicians, establishing their own newspapers, research journals, and laboratories, and as they go on to force reform in the nation s disease-fighting agencies. With his unparalleled access to this community David France illuminates the lives of extraordinary characters, including the closeted Wall Street trader-turned-activist, the high school dropout who found purpose battling pharmaceutical giants in New York, the South African physician who helped establish the first officially recognized buyers club at the height of the epidemic, and the public relations executive fighting to save his own life for the sake of his young daughter. Expansive yet richly detailed, this is an insider's account of a pivotal moment in the history of American civil rights. Powerful, heart-wrenching, and finally exhilarating, How to Survive a Plague is destined to become an essential part of the literature of AIDS.

    Yet somehow, this normal boy became one of the youngest people on whom Dr. Walter Freeman performed his barbaric transorbital—or ice pick—lobotomy.Abandoned by his family within a year of the surgery, Howard spent his teen years in mental institutions, his twenties in jail, and his thirties in a bottle. It wasn’t until he was in his forties that Howard began to pull his life together. But even as he began to live the “normal” life he had been denied, Howard struggled with one question: Why?“October 8, 1960. I gather that Mrs. Dully is perpetually talking, admonishing, correcting, and getting worked up into a spasm, whereas her husband is impatient, explosive, rather brutal, won’t let the boy speak for himself, and calls him numbskull, dimwit, and other uncomplimentary names.”There were only three people who would know the truth: Freeman, the man who performed the procedure; Lou, his cold and demanding stepmother who brought Howard to the doctor’s attention; and his father, Rodney. Of the three, only Rodney, the man who hadn’t intervened on his son’s behalf, was still living. Time was running out. Stable and happy for the first time in decades, Howard began to search for answers. “December 3, 1960. Mr. and Mrs. Dully have apparently decided to have Howard operated on. I suggested [they] not tell Howard anything about it.”Through his research, Howard met other lobotomy patients and their families, talked with one of Freeman’s sons about his father’s controversial life’s work, and confronted Rodney about his complicity. And, in the archive where the doctor’s files are stored, he finally came face to face with the truth.Revealing what happened to a child no one—not his father, not the medical community, not the state—was willing to protect, My Lobotomy exposes a shameful chapter in the history of the treatment of mental illness. Yet, ultimately, this is a powerful and moving chronicle of the life of one man. Without reticence, Howard Dully shares the story of a painfully dysfunctional childhood, a misspent youth, his struggle to claim the life that was taken from him, and his redemption.

     For more than twenty years, Kitty Dukakis battled severe depression with every medication and treatment available. But it wasn't until she tried electroconvulsive therapy- ECT-that she began getting her life back for good. Written with award-winning medical reporter Larry Tye, "Shock" is both the personal story of how ECT dramatically changed Kitty Dukakis's life as well as a captivating look at the science behind ECT, the controversy surrounding it, and the history of its intriguing rebirth in this country. "Shock" explores the stigma afflicting ECT-still a treatment that many hospitals do not administer-and debunks long-held misconceptions about how it is performed. Though some continue to view ECT as a dangerous, even barbaric, procedure, as this book explains there is no scientific evidence to suggest that ECT damages the brain. It can cause side effects like memory loss, but they generally are not far-reaching or long-lasting, especially when newer, lower-impact techniques are employed. In fact, the U.S. surgeon general and the National Institutes of Health agree that for severe depression ECT is safe, and often more effective than antidepressants or psychotherapy. An eye-opening and powerful book about one of the most contentious medical treatments in history, Shock demystifies ECT and brings to life-through Kitty Dukakis's moving account -its impressive capacity to heal. For the millions who suffer from depression, bipolar disorder, and other mental illnesses, it offers real information, practical guidance, and hope.