A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution


Jennifer A. Doudna - 2017
    Two scientists explore the potential of a revolutionary genetics technology capable of easily and affordably manipulating DNA in human embryos to prevent specific diseases, addressing key concerns about related ethical and societal repercussions.

Algorithms to Live By: The Computer Science of Human Decisions


Brian Christian - 2016
    What should we do, or leave undone, in a day or a lifetime? How much messiness should we accept? What balance of new activities and familiar favorites is the most fulfilling? These may seem like uniquely human quandaries, but they are not: computers, too, face the same constraints, so computer scientists have been grappling with their version of such issues for decades. And the solutions they've found have much to teach us.In a dazzlingly interdisciplinary work, acclaimed author Brian Christian and cognitive scientist Tom Griffiths show how the algorithms used by computers can also untangle very human questions. They explain how to have better hunches and when to leave things to chance, how to deal with overwhelming choices and how best to connect with others. From finding a spouse to finding a parking spot, from organizing one's inbox to understanding the workings of memory, Algorithms to Live By transforms the wisdom of computer science into strategies for human living.

Chasing New Horizons: Inside the Epic First Mission to Pluto


Alan Stern - 2018
    More than 3 billion miles from Earth, a small NASA spacecraft called New Horizons screamed past Pluto at more than 32,000 miles per hour, focusing its instruments on the long mysterious icy worlds of the Pluto system, and then, just as quickly, continued on its journey out into the beyond.Nothing like this has occurred in a generation--a raw exploration of new worlds unparalleled since NASA's Voyager missions to Uranus and Neptune--and nothing like it is planned to happen ever again. The photos that New Horizons sent back to Earth graced the front pages of newspapers on all 7 continents, and NASA's website for the mission received more than 2 billion hits in the days surrounding the flyby. At a time when so many think our most historic achievements are in the past, the most distant planetary exploration ever attempted not only succeeded but made history and captured the world's imagination.How did this happen? Chasing New Horizons is the story of the men and women behind the mission: of their decades-long commitment; of the political fights within and outside of NASA; of the sheer human ingenuity it took to design, build, and fly the mission; and of the plans for New Horizons' next encounter, 1 billion miles past Pluto. Told from the insider's perspective of Dr. Alan Stern--the man who led the mission--Chasing New Horizons is a riveting story of scientific discovery, and of how far humanity can go when people focused on a dream work together toward their incredible goal.

Remember: The Science of Memory and the Art of Forgetting


Lisa Genova - 2021
    You might even be worried that these lapses in memory could be an early sign of Alzheimer's or dementia. In reality, for the vast majority of us, these examples of forgetting are completely normal. Why? Because while memory is amazing, it is far from perfect. Our brains aren't designed to remember every name we hear, plan we make, or day we experience. Just because your memory sometimes fails doesn't mean it's broken or succumbing to disease. Forgetting is actually part of being human. In Remember, neuroscientist and acclaimed novelist Lisa Genova delves into how memories are made and how we retrieve them. You'll learn whether forgotten memories are temporarily inaccessible or erased forever and why some memories are built to exist for only a few seconds (like a passcode) while others can last a lifetime (your wedding day). You'll come to appreciate the clear distinction between normal forgetting (where you parked your car) and forgetting due to Alzheimer's (that you own a car). And you'll see how memory is profoundly impacted by meaning, emotion, sleep, stress, and context. Once you understand the language of memory and how it functions, its incredible strengths and maddening weaknesses, its natural vulnerabilities and potential superpowers, you can both vastly improve your ability to remember and feel less rattled when you inevitably forget. You can set educated expectations for your memory, and in doing so, create a better relationship with it. You don't have to fear it anymore. And that can be life-changing.

The Laws of Thermodynamics: A Very Short Introduction


Peter Atkins - 1990
    From the sudden expansion of a cloud of gas to the cooling of hot metal--everything is moved or restrained by four simple laws. Written by Peter Atkins, one of the world's leading authorities on thermodynamics, this powerful and compact introduction explains what these four laws are and how they work, using accessible language and virtually no mathematics. Guiding the reader a step at a time, Atkins begins with Zeroth (so named because the first two laws were well established before scientists realized that a third law, relating to temperature, should precede them--hence the jocular name zeroth), and proceeds through the First, Second, and Third Laws, offering a clear account of concepts such as the availability of work and the conservation of energy. Atkins ranges from the fascinating theory of entropy (revealing how its unstoppable rise constitutes the engine of the universe), through the concept of free energy, and to the brink, and then beyond the brink, of absolute zero. About the Series: Combining authority with wit, accessibility, and style, Very Short Introductions offer an introduction to some of life's most interesting topics. Written by experts for the newcomer, they demonstrate the finest contemporary thinking about the central problems and issues in hundreds of key topics, from philosophy to Freud, quantum theory to Islam.

Behave: The Biology of Humans at Our Best and Worst


Robert M. Sapolsky - 2017
    Sapolsky's storytelling concept is delightful but it also has a powerful intrinsic logic: he starts by looking at the factors that bear on a person's reaction in the precise moment a behavior occurs, and then hops back in time from there, in stages, ultimately ending up at the deep history of our species and its evolutionary legacy.And so the first category of explanation is the neurobiological one. A behavior occurs--whether an example of humans at our best, worst, or somewhere in between. What went on in a person's brain a second before the behavior happened? Then Sapolsky pulls out to a slightly larger field of vision, a little earlier in time: What sight, sound, or smell caused the nervous system to produce that behavior? And then, what hormones acted hours to days earlier to change how responsive that individual is to the stimuli that triggered the nervous system? By now he has increased our field of vision so that we are thinking about neurobiology and the sensory world of our environment and endocrinology in trying to explain what happened.Sapolsky keeps going: How was that behavior influenced by structural changes in the nervous system over the preceding months, by that person's adolescence, childhood, fetal life, and then back to his or her genetic makeup? Finally, he expands the view to encompass factors larger than one individual. How did culture shape that individual's group, what ecological factors millennia old formed that culture? And on and on, back to evolutionary factors millions of years old.The result is one of the most dazzling tours d'horizon of the science of human behavior ever attempted, a majestic synthesis that harvests cutting-edge research across a range of disciplines to provide a subtle and nuanced perspective on why we ultimately do the things we do...for good and for ill. Sapolsky builds on this understanding to wrestle with some of our deepest and thorniest questions relating to tribalism and xenophobia, hierarchy and competition, morality and free will, and war and peace. Wise, humane, often very funny, Behave is a towering achievement, powerfully humanizing, and downright heroic in its own right.

Cultish: The Language of Fanaticism


Amanda Montell - 2021
    We secretly want to know: could it happen to me? Amanda Montell’s argument is that, on some level, it already has . . .Our culture tends to provide pretty flimsy answers to questions of cult influence, mostly having to do with vague talk of “brainwashing.” But the true answer has nothing to do with freaky mind-control wizardry or Kool-Aid. In Cultish, Montell argues that the key to manufacturing intense ideology, community, and us/them attitudes all comes down to language. In both positive ways and shadowy ones, cultish language is something we hear—and are influenced by—every single day.Through juicy storytelling and cutting original research, Montell exposes the verbal elements that make a wide spectrum of communities “cultish,” revealing how they affect followers of groups as notorious as Heaven’s Gate, but also how they pervade our modern start-ups, Peloton leaderboards, and Instagram feeds. Incisive and darkly funny, this enrapturing take on the curious social science of power and belief will make you hear the fanatical language of “cultish” everywhere.

The Island of Knowledge: The Limits of Science and the Search for Meaning


Marcelo Gleiser - 2014
    In so doing, he reaches a provocative conclusion: science, the main tool we use to find answers, is fundamentally limited.These limits to our knowledge arise both from our tools of exploration and from the nature of physical reality: the speed of light, the uncertainty principle, the impossibility of seeing beyond the cosmic horizon, the incompleteness theorem, and our own limitations as an intelligent species. Recognizing limits in this way, Gleiser argues, is not a deterrent to progress or a surrendering to religion. Rather, it frees us to question the meaning and nature of the universe while affirming the central role of life and ourselves in it. Science can and must go on, but recognizing its limits reveals its true mission: to know the universe is to know ourselves.Telling the dramatic story of our quest for understanding, The Island of Knowledge offers a highly original exploration of the ideas of some of the greatest thinkers in history, from Plato to Einstein, and how they affect us today. An authoritative, broad-ranging intellectual history of our search for knowledge and meaning, The Island of Knowledge is a unique view of what it means to be human in a universe filled with mystery.

The Lion in the Living Room: How House Cats Tamed Us and Took Over the World


Abigail Tucker - 2016
    And unlike dogs, cats offer humans no practical benefit. The truth is they are sadly incompetent mouse-catchers and now pose a threat to many ecosystems. Yet, we love them still.Content:Catacombs Cat's cradle What's the catch? The cats that ate the canaries The cat lobby CAT scan Pandora's litter box Lions and toygers and lykoi Nine likes.

The Universe in Your Hand: A Journey Through Space, Time, and Beyond


Christophe Galfard - 2015
    Frizzle were a physics student of Stephen Hawking, she might have written THE UNIVERSE IN YOUR HAND, a wild tour through the reaches of time and space, from the interior of a proton to the Big Bang to the rough suburbs of a black hole. It's friendly, excitable, erudite, and cosmic."—Jordan Ellenberg, New York Times besteselling author of How Not To Be WrongQuantum physics, black holes, string theory, the Big Bang, dark matter, dark energy, parallel universes: even if we are interested in these fundamental concepts of our world, their language is the language of math. Which means that despite our best intentions of finally grasping, say, Einstein's Theory of General Relativity, most of us are quickly brought up short by a snarl of nasty equations or an incomprehensible graph.Christophe Galfard's mission in life is to spread modern scientific ideas to the general public in entertaining ways. Using his considerable skills as a brilliant theoretical physicist and successful young adult author, The Universe in Your Hand employs the immediacy of simple, direct language to show us, not explain to us, the theories that underpin everything we know about our universe. To understand what happens to a dying star, we are asked to picture ourselves floating in space in front of it. To get acquainted with the quantum world, we are shrunk to the size of an atom and then taken on a journey. Employing everyday similes and metaphors, addressing the reader directly, and writing stories rather than equations renders these astoundingly complex ideas in an immediate and visceral way.Utterly captivating and entirely unique, The Universe in Your Hand will find its place among other classics in the field.

The Tangled Tree: A Radical New History of Life


David Quammen - 2018
    In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field—the study of life’s diversity and relatedness at the molecular level—is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection—a type of HGT.David Quammen chronicles these discoveries through the lives of the researchers who made them—such as Carl Woese, the most important little-known biologist of the twentieth century; Lynn Margulis, the notorious maverick whose wild ideas about “mosaic” creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health.

How to Do Nothing: Resisting the Attention Economy


Jenny Odell - 2019
    Here, Jenny Odell sends up a flare from the heart of Silicon Valley, delivering an action plan to resist capitalist narratives of productivity and techno-determinism, and to become more meaningfully connected in the process.

The Soul of an Octopus: A Surprising Exploration Into the Wonder of Consciousness


Sy Montgomery - 2015
    From New England aquarium tanks to the reefs of French Polynesia and the Gulf of Mexico, she has befriended octopuses with strikingly different personalities—gentle Athena, assertive Octavia, curious Kali, and joyful Karma. Each creature shows her cleverness in myriad ways: escaping enclosures like an orangutan; jetting water to bounce balls; and endlessly tricking companions with multiple “sleights of hand” to get food.Scientists have only recently accepted the intelligence of dogs, birds, and chimpanzees but now are watching octopuses solve problems and are trying to decipher the meaning of the animal’s color-changing techniques. With her “joyful passion for these intelligent and fascinating creatures” (Library Journal Editors’ Spring Pick), Montgomery chronicles the growing appreciation of this mollusk as she tells a unique love story. By turns funny, entertaining, touching, and profound, The Soul of an Octopus reveals what octopuses can teach us about the meeting of two very different minds.

Life on the Edge: The Coming of Age of Quantum Biology


Johnjoe McFadden - 2014
    Life remains the only way to make life. Are we still missing a vital ingredient in its creation?      Like Richard Dawkins' The Selfish Gene, which provided a new perspective on how evolution works, Life on the Edge alters our understanding of our world's fundamental dynamics. Bringing together first-hand experience at the cutting edge of science with unparalleled gifts of explanation, Jim Al-Khalili and Johnjoe Macfadden reveal that missing ingredient to be quantum mechanics; the phenomena that lie at the heart of this most mysterious of sciences. Drawing on recent ground-breaking experiments around the world, each chapter in Life on the Edge engages by illustrating one of life's puzzles: How do migrating birds know where to go? How do we really smell the scent of a rose? How do our genes copy themselves with such precision? Life on the Edge accessibly reveals how quantum mechanics can answer these probing questions of the universe. Guiding the reader through the rapidly unfolding discoveries of the last few years, Al-Khalili and McFadden communicate the excitement of the explosive new field of quantum biology and its potentially revolutionary applications, while offering insights into the biggest puzzle of all: what is life? As they brilliantly demonstrate in these groundbreaking pages, life exists on the quantum edge.

Think Again: The Power of Knowing What You Don't Know


Adam M. Grant - 2021
    Evidence has shown that creative geniuses are not attached to one identity, but constantly willing to rethink their stances and that leaders who admit they don't know something and seek critical feedback lead more productive and innovative teams.New evidence shows us that as a mindset and a skilllset, rethinking can be taught and Grant explains how to develop the necessary qualities to do it. Section 1 explores why we struggle to think again and how we can learn to do it as individuals, arguing that 'grit' alone can actually be counterproductive. Section 2 discusses how we can help others think again through learning about 'argument literacy'. And the final section 3 looks at how schools, businesses and governments fall short in building cultures that encourage rethinking.In the end, learning to rethink may be the secret skill to give you the edge in a world changing faster than ever.