Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The birth of genetics in the early 1900s seemed to do precisely that. Gradually, people translated their old notions about heredity into a language of genes. As the technology for studying genes became cheaper, millions of people ordered genetic tests to link themselves to missing parents, to distant ancestors, to ethnic identities. . . .But, Zimmer writes, "Each of us carries an amalgam of fragments of DNA, stitched together from some of our many ancestors. Each piece has its own ancestry, traveling a different path back through human history. A particular fragment may sometimes be cause for worry, but most of our DNA influences who we are--our appearance, our height, our penchants--in inconceivably subtle ways." Heredity isn't just about genes that pass from parent to child. Heredity continues within our own bodies, as a single cell gives rise to trillions of cells that make up our bodies. We say we inherit genes from our ancestors--using a word that once referred to kingdoms and estates--but we inherit other things that matter as much or more to our lives, from microbes to technologies we use to make life more comfortable. We need a new definition of what heredity is and, through Carl Zimmer's lucid exposition and storytelling, this resounding tour de force delivers it. Weaving historical and current scientific research, his own experience with his two daughters, and the kind of original reporting expected of one of the world's best science journalists, Zimmer ultimately unpacks urgent bioethical quandaries arising from new biomedical technologies, but also long-standing presumptions about who we really are and what we can pass on to future generations.

    As the mosquito transformed the landscapes of civilization, humans were unwittingly required to respond to its piercing impact and universal projection of power.The mosquito has determined the fates of empires and nations, razed and crippled economies, and decided the outcome of pivotal wars, killing nearly half of humanity along the way. She (only females bite) has dispatched an estimated 52 billion people from a total of 108 billion throughout our relatively brief existence. As the greatest purveyor of extermination we have ever known, she has played a greater role in shaping our human story than any other living thing with which we share our global village.Imagine for a moment a world without deadly mosquitoes, or any mosquitoes, for that matter? Our history and the world we know, or think we know, would be completely unrecognizable.Driven by surprising insights and fast-paced storytelling, The Mosquito is the extraordinary untold story of the mosquito's reign through human history and her indelible impact on our modern world order.

    Civilization, we are told, could be achieved only by sacrificing those original freedoms or, alternatively, by taming our baser instincts. David Graeber and David Wengrow show how such theories first emerged in the eighteenth century as a conservative reaction to powerful critiques of European society posed by Indigenous observers and intellectuals. Revisiting this encounter has startling implications for how we make sense of human history today, including the origins of farming, property, cities, democracy, slavery, and civilization itself.Drawing on pathbreaking research in archaeology and anthropology, the authors show how history becomes a far more interesting place once we learn to throw off our conceptual shackles and perceive what's really there. If humans did not spend 95 percent of their evolutionary past in tiny bands of hunter-gatherers, what were they doing all that time? If agriculture, and cities, did not mean a plunge into hierarchy and domination, then what kinds of social and economic organization did they lead to? The answers are often unexpected, and suggest that the course of human history may be less set in stone, and more full of playful, hopeful possibilities, than we tend to assume.The Dawn of Everything fundamentally transforms our understanding of the human past and offers a path toward imagining new forms of freedom, new ways of organizing society. This is a monumental book of formidable intellectual range, animated by curiosity, moral vision, and a faith in the power of direct action.

    From climate change to evolution, the rejection of mainstream science among Republicans is growing, as is the denial of expert consensus on the economy, American history, foreign policy and much more. Why won't Republicans accept things that most experts agree on? Why are they constantly fighting against the facts?Science writer Chris Mooney explores brain scans, polls, and psychology experiments to explain why conservatives today believe more wrong things; appear more likely than Democrats to oppose new ideas and less likely to change their beliefs in the face of new facts; and sometimes respond to compelling evidence by doubling down on their current beliefs.  Goes beyond the standard claims about ignorance or corporate malfeasance to discover the real, scientific reasons why Republicans reject the widely accepted findings of mainstream science, economics, and history—as well as many undeniable policy facts (e.g., there were no “death panels” in the health care bill).Explains that the political parties reflect personality traits and psychological needs—with Republicans more wedded to certainty, Democrats to novelty—and this is the root of our divide over reality.Written by the author of The Republican War on Science, which was the first and still the most influential book to look at conservative rejection of scientific evidence. But the rejection of science is just the beginning…Certain to spark discussion and debate, The Republican Brain also promises to add to the lengthy list of persuasive scientific findings that Republicans reject and deny.

    This fascinating collection of historical curiosities explores some of the strangest cases that have perplexed doctors across the world.From seventeenth-century Holland to Tsarist Russia, from rural Canada to a whaler in the Pacific, many are monuments to human stupidity – such as the sailor who swallowed dozens of penknives to amuse his shipmates, or the chemistry student who in 1850 arrived at a hospital in New York with his penis trapped inside a bottle, having unwisely decided to relieve himself into a vessel containing highly reactive potassium. Others demonstrate exceptional surgical ingenuity long before the advent of anaesthesia – such as a daring nineteenth-century operation to remove a metal fragment from beneath a conscious patient’s heart. We also hear of the weird, often hilarious remedies employed by physicians of yore – from crow’s vomit to port-wine enemas – the hazards of such everyday objects as cucumbers and false teeth, and miraculous recovery from apparently terminal injuries.

    Two of the world's great religions - Hinduism and Buddhism - have their origins in South Asia, and the lands east of the Indus River have long been a central hub for trade, migration, and cultural exchange. Today the subcontinent contains 20 percent of the world's population and is a thriving center for global business, making this region one of most significant economic powerhouses in the world.Go inside this thrilling story with A History of India, a breathtaking survey of South Asia from its earliest societies along the Indus and Ganges rivers through the modern challenges of the 21st century. These 36 sweeping lectures enable you to understand the epic scope of the subcontinent's history. Perhaps the most important facet of this history is how diverse the region truly is. Roughly the size of continental Europe, India - along with its neighbors, Pakistan and Bangladesh - contains a myriad of ethnic groups, socioeconomic classes, religions, and cultural mores.In this wide-ranging investigation, you'll: Meet the many religious communities that have coexisted in India, including Hindus, Jains, Buddhists, Muslims, Christians, Jews, and Zoroastrians Delve into the legacies of the Mauryan Empire, the Mughal Empire, and British colonialism - three of the few governments that ever unified the subcontinent Witness the fight for independence from European powers and the partition of the region into the countries of India, Pakistan, and Bangladesh in the 20th century Consider the challenges and opportunities faced by this area today, from expanding urbanization to the vast need for energy sources to the ongoing heated debates about national identity Professor Fisher, who has traveled and taught in South Asia for decades, reveals this complex narrative with skill and compelling insights.1. Introduction to India 32 min 2. The Mughal Empire in 18th-Century India 32 min 3. Indian and British Economic Interests 31 min 4. British Expansion in India (1757-1820) 28 min 5. Knowing the Country: British Orientalism 30 min 6. Race, Gender, and Culture (1750-1850) 30 min 7. The Age of Reform (1830-1850) 30 min 8. The Great Uprising (1857-1858) 27 min 9. Economics and Society under the Raj 29 min 10. Caste and Tribal Identity under Colonialism 29 min 11. The Nationalization of Hinduism (1870-1900) 32 min 12. Indian Muslim Identity and Colonial Rule 31 min 13. The Late-19th-Century British Raj 29 min 14. Princely States and Royalist Relationships 29 min 15. Indian Nationalism and the Freedom Struggle 31 min 16. The Great War and Its Impact on India 29 min 17. Gandhi's Moral-Political Philosophy 29 min 18. The Noncooperation Movement 31 min 19. Indian Muslim Politics between the Wars 29 min 20. The Civil Disobedience Campaign 32 min 21. Britain and Its Empire in the 1940s 30 min 22. The Raj on Its Knees (1945-1947) 30 min 23. A Split India: Negotiating Independence 30 min 24. Reflections on Postcolonial India 29 min

    It often begins in childhood in a darkened theater, grows into something more serious for high school actors, and reaches its passionate zenith when it comes time for love, marriage, and children, who will start the cycle all over again. Americans love musicals. Americans invented musicals. Americans perfected musicals. But what, exactly, is a musical?In The Secret Life of the American Musical, Jack Viertel takes them apart, puts them back together, sings their praises, marvels at their unflagging inventiveness, and occasionally despairs over their more embarrassing shortcomings. In the process, he invites us to fall in love all over again by showing us how musicals happen, what makes them work, how they captivate audiences, and how one landmark show leads to the next—by design or by accident, by emulation or by rebellion—from Oklahoma! to Hamilton and onward.Structured like a musical, The Secret Life of the American Musical begins with an overture and concludes with a curtain call, with stops in between for “I Want” songs, “conditional” love songs, production numbers, star turns, and finales. The ultimate insider, Viertel has spent three decades on Broadway, working on dozens of shows old and new as a conceiver, producer, dramaturg, and general creative force; he has his own unique way of looking at the process and at the people who collaborate to make musicals a reality. He shows us patterns in the architecture of classic shows and charts the inevitable evolution that has taken place in musical theater as America itself has evolved socially and politically.The Secret Life of the American Musical makes you feel as though you’ve been there in the rehearsal room, in the front row of the theater, and in the working offices of theater owners and producers as they pursue their own love affair with that rare and elusive beast—the Broadway hit.

    Finding the "Lost Continent" 2. Africa's Many Natural Environments 3. A Virtual Tour of the Great Land 4. The Cradle of Humankind 5. Crops, Cattle, Iron-Taming a Continent 6. Kinship and Community-Societies Take Shape 7. Like Nothing Else-The Ancient Nile Valley 8. Soul and Spirit-Religion in Africa 9. Ethiopia-Outpost of Christianity 10. West Africa's "Golden Age" 11. The Swahili Commercial World 12. Great Zimbabwe and the Cities of the South 13. The Atlantic Slave Trade-The Scope 14. The Atlantic Slave Trade-The Impact 15. South Africa-The Dutch Cape Colony 16. South Africa-The Zulu Kingdom 17. South Africa-The Frontier and Unification 18. South Africa-Diamonds and Gold 19. Prelude to the "Scramble for Africa" 20. European Conquest and African Resistance 21. Colonial Africa-New Realities 22. Colonial Africa-Comparisons and Change 23. The Lion Awakens-The Rise of Nationalism 24. The Peaceful Paths to Independence 25. The Congo-Promise and Pain 26. Segregation to Apartheid in South Africa 27. The Armed Struggles for Independence 28. The First Taste of Freedom 29. The Taste Turns Sour 30. The World Turns Down-The "Permanent Crisis" 31. A New Dawn? The Democratic Revival 32. The South African Miracle 33. The Unthinkable-The Rwanda Genocide 34. The New Plague-HIV/AIDS in Africa 35. Zimbabwe-Background to Contemporary Crisis 36. Africa Found

    Thanks to advances in technology and clever new uses of existing data, now we know that planetary systems and possibly even a new Earth can be found throughout galaxies near and far.We are living during a new golden age of planetary discovery, with the prospect of finding many worlds like Earth. Most of the thousands of planets we've detected can't be imaged directly, but researchers are able to use subtle clues obtained in ingenious ways to assemble an astonishing picture of planetary systems far different from our own. We are in the midst of an astronomical revolution, comparable to the Copernican revolution that established our current view of the solar system - and we invite you to take part.Embark on this unrivaled adventure in 24 lectures by a veteran planet hunter. Designed for everyone from armchair explorers to serious skywatchers, The Search for Exoplanets follows the numerous twists and turns in the hunt for exoplanets - the false starts, the sudden breakthroughs, and the extraordinary discoveries. Explore systems containing super-Earths, mini-Neptunes, lava worlds, and even stranger worlds. You also get behind-the-scenes information on the techniques astronomers used to find evidence of planets at mind-boggling distances from our home base. Learn how astronomers determine how many planets are in a system as well as how large they are and the characteristics of their atmospheres. You will feel like Dr. Watson in the presence of Sherlock Holmes as Professor Winn extracts a wealth of information from a spectrum, a light graph, a diffraction pattern, and other subtle clues.©2015 The Teaching Company, LLC (P)2015 The Great Courses

    The Grand Question of Lifes Origins 2. The Historical Setting of Origins Research 3. What Is Life? 4. Is There Life on Mars? 5. Earths Oldest Fossils 6. Fossil Isotopes 7. Molecular Biosignatures 8. Emergence 9. The Miller-Urey Experiment 10. Life from the Bottom of the Sea 11. The Deep, Hot Biosphere 12. Experiments at High Pressure 13. More Experiments Under Pressure 14. Deep Space Dust, Molten Rock, and Zeolite 15. Macromolecules and the Tree of Life 16. Lipids and Membrane Self-Organization 17. Life on Clay, Clay as Life 18. Lifes Curious Handedness 19. Self-Replicating Molecular Systems 20. Günter Wächtershäusers Grand Hypothesis 21. The RNA World 22. The Pre-RNA World 23. Natural Selection and Competition 24. Three Scenarios for the Origin of Life