But for thousands of years, people have done things like this—and things that make radioactive underpants seem downright sensible! In their hit podcast, Sawbones, Sydnee and Justin McElroy breakdown the weird and wonderful way we got to modern healthcare. And some of the terrifying detours along the way.Every week, Dr. Sydnee McElroy and her husband Justin amaze, amuse, and gross out (depending on the week) hundreds of thousands of avid listeners to their podcast, Sawbones. Consistently rated a top podcast on iTunes, with over 15 million total downloads, this rollicking journey through thousands of years of medical mishaps and miracles is not only hilarious but downright educational. While you may never even consider applying  boiled weasel to your forehead (once the height of sophistication when it came to headache cures), you will almost certainly face some questionable medical advice in your everyday life (we’re looking at you, raw water!) and be better able to figure out if this is a miracle cure (it’s not) or a scam. Table of Contents:Part One: The Unnerving The Resurrection Men Fun w Galvanism Weird Weight Loss Miracle Cure: Opium Black Plague Heroes of Misguided Medicine: Pliny the Elder Erectile Dysfunction The Doctor Is In: Listener Questions Answered Don’t Drill a Hole in Your HeadPart Two: The Gross Mummy Medicine The Guthole Bromance The Unkillable Phineas Gage Max Drank Poopy Water Heroes of Misguided Medicine: Robert Liston Golden Showers of Health Miracle Cure-All: Radium Dr. John Romulus Brinkley The Doctor Is In Q&A Just (Four) Humour Me The Camel Dung MiraclePart Three: The Weird The Dancing Plague Bad Medicine: Tobacco for Health The Seasick-Proof Saloon Miracle Cure-All: Vinegar The Doctor Is In Q&A Heroes of Misguided MedicinePart Four: The Awesome The Poison Squad Bad Medicine: Self Experimentation Eat Your Chocolate! Heroes of Misguided Medicine Parrot Fever Miracle Cure-All: Honey The Miraculous Polio Vaccine The Doctor Is In

    Now he gathers the best of his best, updated and expanded upon, to guide readers on a mind-bending tour of the far frontier, and how these advances are radically transforming our lives. From the ways science and technology are fundamentally altering our bodies and our world (the world’s first bionic soldier, the future of evolution) to those explosive collisions between science and culture (life extension and bioweapons), we’re crossing moral and ethical lines we’ve never faced before.As Kotler writes, “Life is tricky sport—and that's the emotional core of this story, the real reason we can’t put Pandora back in the box. When you strip everything else away, technology is nothing more than the promise of an easier tomorrow. It’s the promise of hope. And how do you stop hope?”Join Kotler in this fascinating exploration of our incredible next: a deep dive into those future technologies happening now—and what it means to be a part of this brave new world.

    From the Space Shuttle training toilet to a crash test of NASA’s new space capsule, Mary Roach takes us on the surreally entertaining trip into the science of life in space and space on Earth.

    The implications of their discoveries form tomorrow's headlines, yet Angier writes about the scientists themselves and not merely theri successes. 4-page photo insert.

    

    Isolated and desolate, they were largely overlooked by early explorers until Charles Darwin arrived there in the 1830s. It was Darwin who recognized that Galapagos' isolation and desolation were advantages: the paucity of species and lack of outside influences made the workings of natural selection crystal clear. Since then, every important advance and controversy in evolutionary thinking has had its reflection on the Galapagos. In every sense-intellectually, institutionally, and culturally-the history of science on these islands is a history of the way evolutionary science was done for the past 150 years. Evolution's Workshop tells the story of Darwin's explorations there; the fabulous Gilded Age expeditions, run from rich men's gigantic yachts, that featured rough-and-ready science during the day and black-tie dinners every night; the struggle for control of research on the Galapagos; the current efforts by "creation scientists" to use the Galapagos to undercut evolutionary teaching; and many other compelling stories.

     Many of those most closely involved in cracking the Enigma code – Alistair Denniston, Frank Birch, Dilly Knox – had wrestled with German naval codes for most of the First World War. By the end of the war they had been successfully cracking a new code every day, from their secret Room 40 at the Old Admiralty Building, in a London blacked out for Zeppelin Raids. The techniques they developed then, the ideas that they came to rely on, the people they came to trust, had been developed the hard way, under intense pressure and absolute secrecy during the First World War. Operation Primrose Operation Primrose tells the story of the capture of U-110 – and with it a working Enigma machine. One of the biggest secrets of the war, the capture of that one machine turned the tide of the war. Turing and his colleagues at Bletchley Park worked tirelessly to crack the code, and with the working Enigma machine they finally had their break-through moment. This book sets the story, and the Enigma cryptographers, in context – at the heart of the Battle of the Atlantic, when it reached its crescendo in the pursuit of the battleship Bismarck the week after U110 was taken. It sets Bletchley Park in its wider context too, at the heart of an intricate and maverick network of naval intelligence, tracking signals and plotting them to divert convoys around waiting U-boats, involving officers like James Bond’s future creator, Ian Fleming. It also sets out the most important context of all, forgotten in so much of the Enigma history: that Britain’s own naval code had already been cracked, and its signals were being read, thanks to the efforts of Turing’s opposite number, the German naval cryptographer, Wilhelm Tranow. An exciting and enthralling true story ‘Operation Primrose’ is an excellently researched piece on the race for naval supremacy in the Second World War. Alan Turing Mathematician, philosopher, codebreaker. Turing was one of the most original thinkers of the last century - and the man whose work helped create the computer-driven world we now inhabit. But he was also an enigmatic figure, deeply reticent yet also strikingly naïve. Turing’s openness about his homosexuality at a time when it was an imprisonable offence ultimately led to his untimely death at the age of only forty-one. Alan Turing: Unlocking the Enigma seeks to find the man behind the science, illuminating the life of a person who is still a shadowy presence behind his brilliant achievements. Turing was instrumental in cracking the Nazi Enigma machines at the top secret code breaking establishment at Bletchley Park during the Second World War. But his achievements were to be tragically overshadowed by his supposedly subversive views and for his sexuality. Praise for David Boyle: ‘The tone of the book may be gloomy but there is plenty of entertainment value …’ - Anne Ashworth, The Times ‘Exhilarating’ - Daily Mail ‘He tells these stories, on the whole persuasively and with some startling asides.

    When research suggests how to harness brain evolution, a hunt ensues for a missing link―one that allows to design humans with skills that prodigies of old would have envied.As germline engineering and biological enhancement have become routine, ancient doubts have emerged under new guises: Who are we? Is there a purpose to life? Why is there so much suffering? When faith and science fail to answer these questions, personal greed and national interest quickly fill the void. But gene selection is expensive, and many are excluded from its benefits. The stage is set for tribalism and social discontent on a scale without precedent, and those caught in the fray, whether by choice or by chance, must play roles not always to their liking in the struggle of all creatures against the arbitrariness of existence.

    Humans have feared them for centuries, long considering them the assassins and pariahs of the natural world.Now, in Venomous, the biologist Christie Wilcox investigates and illuminates the animals of our nightmares, arguing that they hold the keys to a deeper understanding of evolution, adaptation, and immunity. She reveals just how venoms function and what they do to the human body. With Wilcox as our guide, we encounter a jellyfish with tentacles covered in stinging cells that can kill humans in minutes; a two-inch caterpillar with toxic bristles that trigger hemorrhaging; and a stunning blue-ringed octopus capable of inducing total paralysis. How do these animals go about their deadly work? How did they develop such intricate, potent toxins? Wilcox takes us around the world and down to the cellular level to find out.Throughout her journey, Wilcox meets the intrepid scientists who risk their lives studying these lethal beasts, as well as “self-immunizers” who deliberately expose themselves to snakebites. Along the way, she puts her own life on the line, narrowly avoiding being envenomated herself. Drawing on her own research, Wilcox explains how venom scientists are untangling the mechanisms of some of our most devastating diseases, and reports on pharmacologists who are already exploiting venoms to produce lifesaving drugs. We discover that venomous creatures are in fact keystone species that play crucial roles in their ecosystems and ours—and for this alone, they ought to be protected and appreciated.Thrilling and surprising at every turn, Venomous will change everything you thought you knew about the planet’s most dangerous animals.

    It touches on its evolutionary development, its algorithmic nature and its scientific history by bridging ideas across Neuroscience, Computer Science, Biotechnology, Evolutionary History, Cognitive Science, Political Philosophy, and Artificial Intelligence.Never before had there been nearly as many scientists, resources or productive research focused on these topics, and humanity has achieved some understanding and some clarification. With the speed of progress it is timely to communicate an overreaching perspective, this book puts an emphasis on conveying the essential questions and what we know about their answers in a simple, clear and exciting way.Humans, along with the first RNA molecules, the first life forms, the first brains, the first conscious animals, the first societies and the first artificial agents constitute an amazing and crucial development in a path of increasingly complex computational intelligence. And yet, we occupy a minuscule time period in the history of Earth, a history that has been written by Genes, by Cultures and by Consciousnesses. If we abandon our anthropomorphic bias it becomes obvious that Humans are not so special after all. We are an important but short and transitory step among many others in a bigger story. The story of our computational minds, which is ours but not only ours. What is the relationship between computation, cognition and everything else? What is life and how did it originate? What is the role of culture in human minds? What do we know about the algorithmic nature of the mind, can we engineer it? What is the computational explanation of consciousness? What are some possible future steps in the evolution of minds? The underlying thread is the computational nature of the Mind which results from the mixture of Genes, Cultures and Consciousness. While these three interact in complex ways, they are ultimately computational systems on their own which appeared at different stages of history and which follow their own selective processes operating at different time scales. As technology progresses, the distinction between the three components materializes and will be a key determinant of the future.Among the many topics covered are the origin of life, the concept of computation and its relation to Turing Machines, cultural evolution and the notion of a Selfish Meme, free will and determinism, moral relativity, the hard problem of consciousness, the different theories of concepts from the perspective of cognitive science, the current status of AI and Machine Learning including the symbolic vs sub-symbolic dichotomy, the contrast between logical reasoning and neural networks, and the recent history of Deep Learning, Geoffrey Hinton, DeepMind and its algorithm AlphaGo. It also develops on the history of science and looks into the possible future building on the work of authors like Daniel Dennett, Yuval Harari, Richard Dawkins, Francis Crick, George Church, David Chalmers, Susan Carey, Stanislas Dehaene, Robert Boyd, Joseph Henrich, Daniel Kahneman, Moran Cerf, Josh Tenenbaum, David Deutsch, Steven Pinker, Ray Kurzweil, John von Neumann, Herbert Simon and many more. Andres Campero is a researcher and PhD student at the Brain and Cognitive Sciences Department and at the Computer Science and Artificial Intelligence Laboratory at the Massachusetts Institute of Technology (MIT).

    To the right listener, they tell us all about themselves: where they came from, how they lived, how they died - and who killed them. Forensic scientists can unlock the mysteries of the past and help justice to be done using the messages left by a corpse, a crime scene or the faintest of human traces. Forensics uncovers the secrets of forensic medicine, drawing on interviews with top-level professionals, ground-breaking research and Val McDermid's own experience to lay bare the secrets of this fascinating science. And, along the way, she wonders at how maggots collected from a corpse can help determine time of death, how a DNA trace a millionth the size of a grain of salt can be used to convict a killer and how a team of young Argentine scientists led by a maverick American anthropologist uncovered the victims of a genocide.In her crime novels, Val McDermid has been solving complex crimes and confronting unimaginable evil for years. Now, she's looking at the people who do it for real, and real crime scenes. It's a journey that will take her to war zones, fire scenes and autopsy suites, and bring her into contact with extraordinary bravery and wickedness, as she traces the history of forensics from its earliest beginnings to the cutting-edge science of the modern day.

     I am an independent mobile app entrepreneur just like you, and I wrote this book to teach you all my strategies for how to: - Get 1,000,000+ downloads from mobile app store marketing - Save money by doing your own ASO (search engine optimization SEO for Android and the Apple App stores) better than most consultants you might consider hiring - Create an app marketing strategy outside the app stores by getting press coverage and learning how to promote an app using social media and social sharing - Make money with effective app store monetization to help you maximize your app revenue with subscriptions, in-app purchases, publishing effective ads, selling affiliate products and other strategies used by successful mobile app businesses - Create a successful mobile app business I wrote this book with all my heart and soul. The book draws on my own years of experience building top apps in my niche, promoting apps, making money with my apps, and coaching other app entrepreneurs on how they can make turn their mobile apps into successful businesses. You will be getting the best of all worlds. First, I have very deep hands on experience building and growing my own apps. Second, I have a wealth of experience coaching and observing other app entrepreneurs whose experiences and aspirations are probably very similar to yours. In this book you get all the insights from me making my own apps a success, and the insights of the cumulative experiences of the people I've coached. This is a very to the point book with many actionable tips and strategies for how to promote your mobile app (iPhone or Android), make money from your smartphone applications, and generally treat it as a real business. All suggestions in this book are based on my own experiences promoting my own problemio.com business apps which at the point of latest revision of this book have cumulative 1,000,000+ downloads, and insights of me having coached over 100 other app entrepreneurs. I am an independent mobile application developer and mobile application entrepreneur just like you. I am not a multi-million dollar app development studio or a big company. If you are an independent app developer just like me, you can use the mobile application marketing strategies that I outline in this book. Many of the strategies are simple and effective, and you can begin working on them as early as today. The book contains over 20 strategies to promote your apps. They all worked for my apps and they will help you grow your app to its highest potential. After growing your app, you will be able to make good money from your app, and achieve the goals that you have for your app business. Get the book now, and become a pro at app store marketing (app store SEO which is otherwise known as ASO), and start increasing your app downloads and revenue today!

    It is written to impart a sense of intellectual history of biochemistry, an understanding of the tools and approaches used to solve biochemical puzzles, and a hint of the excitement that accompanies new discoveries. This edition has been thoroughly updated to reflect the most recent advances in biochemistry, particularly in the areas of genomics and structural biology. A new chapter focuses on cytoskeletal and motor proteins, currently one of the most active areas of research in biochemistry.

    Table of Contents General Information Vol I Diversity in the Living World Structural Organisation in Plants and Animals Cell Structure and Function Plant Physiology Human Physiology Vol II Reproduction Genetics and Evolution Biology and Human Welfare Biotechnology and Its Applications Ecology and Environment Some More Additional Topics Assertion and Research Questions top

    The most trusted sources in the auto industry have called its Model S the most advanced, safest and best-performing car ever built - and it doesn’t use a drop of gasoline. Tesla has changed the way the public perceives electric vehicles, and inspired the major automakers to revive their own dormant efforts to sell EVs. However, even amidst the avalanche of media coverage that followed the triumph of the Model S, few have grasped the true significance of what is happening. Tesla has redefined the automobile, sparked a new wave of innovation comparable to the internet and mobile computing revolutions, and unleashed forces that will transform not just the auto industry, but every aspect of society. The Tesla story is one part of an ongoing tide of change driven by the use of information technology to eliminate “friction” such as geographic distance, middlemen and outdated regulations. Tesla is simply applying the new order to the auto industry, but the automobile is such a pervasive influence in our lives that redefining how it is designed, built, driven and sold will have sweeping effects in unexpected areas. Just as Tesla built the Model S as an electric vehicle “from the ground up,” it has taken an outsider’s approach to the way it markets its cars. Its direct sales model has drawn legal challenges from entrenched auto dealers, who fear that their outdated business model will be destroyed. Its systems approach to the software and electronics in its cars has highlighted how far behind the technological times the major automakers are. It’s easy to see why readers find Tesla irresistible. CEO Elon Musk is a superstar entrepreneur, a “nauseatingly pro-US” immigrant and the leader of two other cutting-edge companies. Tesla dares to challenge the establishment behemoths and, so far at least, has handily beaten them at their own game. In this history of the 21st century’s most exciting startup, Charles Morris begins with a brief history of EVs and a biography of Tesla’s driving force, Elon Musk. He then details the history of the company, told in the words of the Silicon Valley entrepreneurs who made it happen. There are many fascinating stories here: Martin Eberhard’s realization that there were many like himself, who loved fast cars but wanted to help the environment and bring about the post-oil age; the freewheeling first days, reminiscent of the early internet era; the incredible ingenuity of the team who built the Roadster; Tesla’s near-death experience and miraculous resurrection; the spiteful split between the company’s larger-than-life leaders; the gloves-off battles with hostile media such as Top Gear and the New York Times; and the media’s ironic about-face when the magnificent Model S won the industry’s highest honors, and naysayers became cheerleaders overnight. And the story is just beginning: Tesla has breathtakingly ambitious plans for the future.This book was updated May 1, 2015 to include the latest on the Gigafactory and the D package.