As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    In addressing a wide range of women’s choices—from using birth control to taking the morning-after pill, from adopting a child to putting a child up for adoption, from having an abortion to bringing a pregnancy to full term—Choice explores the complexities inherent in every reproductive decision.Including twenty-four honest, heartrending essays from established writers such as Francine Prose, Jacquelyn Mitchard, Pam Houston, Ann Hood, and Sarah Messer and emerging talents such as Kimi Faxon Hemingway, Stephanie Anderson, and Ashley Talley, Choice will allow you to truly understand the meaning of the word “choice”—regardless of what side of the debate you stand on.

    The niece of Theodore Roosevelt, she married a distant relative and Columbia University law student named Franklin Delano Roosevelt; he gradually ascended throughout the world of New York politics to reach the U.S. presidency in 1932. Throughout his three terms, Eleanor Roosevelt was not only intimately involved in FDR’s personal and political life, but led women’s organizations and youth movements and fought for consumer welfare, civil rights, and improved housing. During World War II she traveled with her husband to meet leaders of many powerful nations; after his death in 1945 she worked as a UN delegate, chairman of the Commission on Human Rights, newspaper columnist, Democratic party activist, world-traveler, and diplomat. By the end of her life, Eleanor Roosevelt was recognized throughout the world for her fortitude and commitment to the ideals of liberty and human rights. Her autobiography constitutes a self-portrait no biography can match for its candor and liveliness, its wisdom, tolerance, and breadth of view—a self-portrait of one of the greatest American humanitarians of our time.

    She moved in the most exclusive circles in Washington, D.C., rubbed elbows with big politicians, and worked on Capitol Hill. As far as she was concerned, she was changing the world. And then her mother had a heart attack. Carolyn came home to help her father with his rural medical practice in the Tennessee mountains. She'd fill in for a few days as the receptionist until her mother could return to work. Or so she thought. But days turned into weeks. Her job now included following hazmat regulations for cleaning up bodily fluids; maintaining composure when confronted with a splinter the size of a steak knife; distinguishing between a "pain," a "strain," and a "sprain" on indecipherable Medicare forms; and tending to the loquacious Miss Hiawatha, whose daily doctor visits were never billed.Eventually, Jourdan gave up her Mercedes and made do with a twenty-year-old postal jeep. She shed her suits for scrubs. And the funny thing was, she liked her new life. As she watched her father work tirelessly and uncomplainingly, she saw what making a difference really meant: being on call all hours of the day and night, tolerating the local drug addict's frequent phone calls, truly listening to Miss Hiawatha. It meant just showing up, every day, and taking care of every person in Strawberry Plains and beyond, whether he got paid to do it or not. And for his daughter, it meant learning that her real place to change the world was right here—in her hometown—by her father's side.

    But what happens when doctors fall apart?Funny, fresh, and deeply affecting, We Are All Perfectly Fine is the story of a married mother of three on the brink of personal and professional collapse who attends rehab with a twist: a meditation retreat for burned-out doctors.Jillian Horton, a general internist, has no idea what to expect during her five-day retreat at Chapin Mill, a Zen centre in upstate New York. She just knows she desperately needs a break. At first she is deeply uncomfortable with the spartan accommodations, silent meals and scheduled bonding sessions. But as the group struggles through awkward first encounters and guided meditations, something remarkable happens: world-class surgeons, psychiatrists, pediatricians and general practitioners open up and share stories about their secret guilt and grief, as well as their deep-seated fear of falling short of the expectations that define them. Jillian realizes that her struggle with burnout is not so much personal as it is the result of a larger system failure, and that compartmentalizing your most difficult emotions—a coping strategy that is drilled into doctors—is not useful unless you face these emotions too.Jillian Horton throws open a window onto the flawed system that shapes medical professionals, revealing the rarely acknowledged stresses that lead doctors to depression and suicide, and emphasizing the crucial role of compassion not only in treating others, but also in taking care of ourselves.

    Some of Birth Day’s many topics include• The evolution of human childbirth—or, why do gorillas have it so easy?• The first five minutes of life—scuba divers, astronauts, and the amazing adaptations that transform a fetus into an air-breathing, out-in-the-world baby• Cesarean section—a look at its origins, its future, and how it came to be the most frequently performed operation in American hospitals• Pain and politics—the age-old quest for painless childbirth, starring Adam and Eve, Queen Victoria, a nineteenth-century medical brawl, and the rise of today’s “epidural monoculture”• Daddies—raging paternal hormones, hidden anxieties, and the emotional evolution of men (including the author, his father, and grandfather) as they approach fatherhood• The five senses at birth—does light enter the womb? how loud is it in there? what is a newborn baby searching for with those first anxious glances?• A tour of the newborn body—springy skulls, hairy ears, innies and outies, the advantages (and disadvantages) of looking like your father, and why the United States is one of the world’s most circumcised nations.

    This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

    At his death last spring, Roueche left behind seven new narratives that have never been published in book form. This book collects these works along with one earlier classic--all relating true tales of strange illnesses, rare diseases, and the brilliant minds who race to understand and conquer them.

    She woke up one morning and her entire history—the life she had lived—crumbled beneath her.Inheritance is a book about secrets—secrets within families, kept out of shame or self-protectiveness; secrets we keep from one another in the name of love. It is the story of a woman’s urgent quest to unlock the story of her own identity, a story that has been scrupulously hidden from her for more than fifty years, years she had spent writing brilliantly, and compulsively, on themes of identity and family history. It is a book about the extraordinary moment we live in—a moment in which science and technology have outpaced not only medical ethics but also the capacities of the human heart to contend with the consequences of what we discover.

    Despite her flapping arms and shaking legs, she continued to speak clearly and was able to finish her speech. It was as if she had suddenly become two people: a calm orator and a shuddering wreck. Then the seizures happened again and again. The Shaking Woman tracks Hustvedt’s search for a diagnosis, one that takes her inside the thought processes of several scientific disciplines, each one of which offers a distinct perspective on her paroxysms but no ready solution. In the process, she finds herself entangled in fundamental questions: What is the relationship between brain and mind? How do we remember? What is the self?During her investigations, Hustvedt joins a discussion group in which neurologists, psychiatrists, psychoanalysts, and brain scientists trade ideas to develop a new field: neuropsychoanalysis. She volunteers as a writing teacher for psychiatric in-patients at the Payne Whitney clinic in New York City and unearths precedents in medical history that illuminate the origins of and shifts in our theories about the mind-body problem. In The Shaking Woman, Hustvedt synthesizes her experience and research into a compelling mystery: Who is the shaking woman? In the end, the story she tells becomes, in the words of George Makari, author of Revolution in Mind, “a brilliant illumination for us all.”

    She learned, among other things, that her instincts are good, her kids are really resilient, and that, in the fight against breast cancer, the journey for patients, family, and friends can be a surprisingly positive, life-changing experience. Some five years younger than the AMA-recommended age for mammograms, Jennie Nash insisted she be tested, not because of a lump but because of a hunch brought on by a friend's battle with lung cancer. Jennie was as shocked to discover as her friend had been that cancer knows no age limits. From detection and surgery to reconstruction and recovery, Jennie gives readers a road map for a journey no one chooses to take. She details both the large and small lessons learned along the way: the importance of a child's birthday cake; the pleasure of wearing a beautiful, provocative red dress; how to be grateful rather than guilty when someone brings lasagne to the door; and that sometimes the only difference between getting to live and having to die is luck. A celebration of survival, Jennie Nash's account transforms one of life's most harrowing experiences into a story of reassurance and enlightenment.

    Born in a rural village in 1940, Wangari Maathai was already an iconoclast as a child, determined to get an education even though most girls were uneducated. We see her studying with Catholic missionaries, earning bachelor’s and master’s degrees in the United States, and becoming the first woman both to earn a PhD in East and Central Africa and to head a university department in Kenya. We witness her numerous run-ins with the brutal Moi government. She makes clear the political and personal reasons that compelled her, in 1977, to establish the Green Belt Movement, which spread from Kenya across Africa and which helps restore indigenous forests while assisting rural women by paying them to plant trees in their villages. We see how Maathai’s extraordinary courage and determination helped transform Kenya’s government into the democracy in which she now serves as assistant minister for the environment and as a member of Parliament. And we are with her as she accepts the Nobel Peace Prize, awarded in recognition of her “contribution to sustainable development, human rights, and peace.” In Unbowed, Wangari Maathai offers an inspiring message of hope and prosperity through self-sufficiency.

    Like twelve million other Americans, Sandra Beasley suffers from food allergies. Her allergies—severe and lifelong—include dairy, egg, soy, beef, shrimp, pine nuts, cucumbers, cantaloupe, honeydew, mango, macadamias, pistachios, cashews, swordfish, and mustard. Add to that mold, dust, grass and tree pollen, cigarette smoke, dogs, rabbits, horses, and wool, and it’s no wonder Sandra felt she had to live her life as “Allergy Girl.” When butter is deadly and eggs can make your throat swell shut, cupcakes and other treats of childhood are out of the question—and so Sandra’s mother used to warn guests against a toxic, frosting-tinged kiss with “Don’t kill the birthday girl!” It may seem that such a person is “not really designed to survive,” as one blunt nutritionist declared while visiting Sandra’s fourth-grade class. But Sandra has not only survived, she’s thrived—now an essayist, editor, and award-winning poet, she has learned to navigate a world in which danger can lurk in an unassuming corn chip. Don’t Kill the Birthday Girl is her story. With candor, wit, and a journalist’s curiosity, Sandra draws on her own experiences while covering the scientific, cultural, and sociological terrain of allergies. She explains exactly what an allergy is, describes surviving a family reunion in heart-of-Texas beef country with her vegetarian sister, delves into how being allergic has affected her romantic relationships, exposes the dark side of Benadryl, explains how parents can work with schools to protect their allergic children, and details how people with allergies should advocate for themselves in a restaurant. A compelling mix of memoir, cultural history, and science, Don’t Kill the Birthday Girl is mandatory reading for the millions of families navigating the world of allergies—and a not-to-be-missed literary treat for the rest of us.

    A National Book Critics Circle Award finalist and the winner of the PEN Center West literary award.

    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.