Life's Greatest Secret: The Race to Crack the Genetic Code


Matthew Cobb - 2015
    Just a half century ago, this idea was revolutionary. In April 1953, James Watson and Francis Crick published in Nature their groundbreaking work revealing the double helix structure of DNA. While this discovery received wide attention from both mainstream media and the academic community, it was just one part of the bigger story in this history of molecular biology. By the mid-1950s, the scientific community confirmed that genes were indeed comprised of DNA; they just needed to crack the genetic code—and the race was on. Life’s Greatest Secret is the full and rich history of this challenge and the characters—many of whom were not biologists—whose work contributed to this grand scientific endeavor: mathematician and father of cybernetics Norbert Wiener, physicist Erwin Schrödinger, information theorist Claude Shannon, and biologists Jacques Monod and Marshall Nirenberg.In Life’s Greatest Secret, science historian and zoologist Matthew Cobb shows that the race to crack the genetic code was mostly a matter of craft—individuals or small groups struggling with ideas and concepts as much as they were with facts, trying to find the right experiment to answer the right questions, even if they didn’t know what the questions were, and finding that, even when the most definitive answer served mostly to reveal more ignorance, whether in 1953, with Watson and Crick, or in 1961, when Nirenberg and Matthaei showed how DNA codes for specific amino acids, and again and again thereafter, or in 2000, with the first publication of a human genome. Each discovery was a leap forward in our understanding of the natural world and our place within in, akin to the discoveries of Galileo and Einstein in the realm of physics, or the publication of Darwin’s On the Origin of Species. And each served to show how much bigger the problem was that anyone had previously imagined, a trend that continues, as Cobb shows, even today, whether we are discussing gene regulation, epigenetics, or GMOs.Life’s Greatest Secret is a story of ideas and of experimentation, of ingenuity, insight, and dead-ends, in the hunt to make the greatest discovery of twentieth century biology. Ultimately, though, this is a story of humans exploring what it is that makes us human.

Sloths!


William Hartston - 2018
    Thanks largely to YouTube clips posted by the sloth orphanage in Costa Rica, sloths have attracted a vast audience of admirers. Instead of seeing them as ridiculous anachronisms of which we know little, they have turned into creatures considered by many to be the most endearing on earth.Over much the same period, scientific investigations have also changed our view of sloths. No longer are they seen as total misfits in the modern world but, in the words of one specialist sloth investigator, they are 'masters of an alternative lifestyle'.In this wonderfully entertaining celebration of this most unique of creatures, William Hartston reveals the fascinating history of the sloth, from the prehistoric ground sloth to modern pygmy sloths in Panama, explores the current state of the science of sloths and reveals the truth behind sloth behaviour.

Mosquito: A Natural History of Our Most Persistent and Deadly Foe


Andrew Spielman - 2001
    But these tiny insects, once merely a seasonal annoyance, now are capturing headlines worldwide as new information emerges about the diseases they carry, their migratory population, and their growing resistance to pesticides.Harvard professor Andrew Spielman has dedicated his life to understanding this insect, a passion that makes him the perfect guide to their amazing world and the perfect author of this lively, accessible book that offers an intriguing and horrifying mosquito-eye view of nature and man. He explains where mosquitoes breed, and how they die, showing us their natural foes and man-made enemies while explaining the myriad diseases they bring to all corners of the world. Spielman offers colorful examples of how the mosquito has insinuated itself into human history, from the defeat of Sir Francis Drake's fleet to the death of thousands of Frenchmen working on the Panama Canal to the recent widespread West Nile panic in New York City. Filled with little-known facts and illuminating anecdotes that bring this tiny being into larger focus, Mosquito offers fascinating, alarming, and convincing evidence that the sooner we get to know this little creature, the better off we'll be.

Head First Java


Kathy Sierra - 2005
    You might think the problem is your brain. It seems to have a mind of its own, a mind that doesn't always want to take in the dry, technical stuff you're forced to study. The fact is your brain craves novelty. It's constantly searching, scanning, waiting for something unusual to happen. After all, that's the way it was built to help you stay alive. It takes all the routine, ordinary, dull stuff and filters it to the background so it won't interfere with your brain's real work--recording things that matter. How does your brain know what matters? It's like the creators of the Head First approach say, suppose you're out for a hike and a tiger jumps in front of you, what happens in your brain? Neurons fire. Emotions crank up. Chemicals surge. That's how your brain knows.And that's how your brain will learn Java. Head First Java combines puzzles, strong visuals, mysteries, and soul-searching interviews with famous Java objects to engage you in many different ways. It's fast, it's fun, and it's effective. And, despite its playful appearance, Head First Java is serious stuff: a complete introduction to object-oriented programming and Java. You'll learn everything from the fundamentals to advanced topics, including threads, network sockets, and distributed programming with RMI. And the new. second edition focuses on Java 5.0, the latest version of the Java language and development platform. Because Java 5.0 is a major update to the platform, with deep, code-level changes, even more careful study and implementation is required. So learning the Head First way is more important than ever. If you've read a Head First book, you know what to expect--a visually rich format designed for the way your brain works. If you haven't, you're in for a treat. You'll see why people say it's unlike any other Java book you've ever read.By exploiting how your brain works, Head First Java compresses the time it takes to learn and retain--complex information. Its unique approach not only shows you what you need to know about Java syntax, it teaches you to think like a Java programmer. If you want to be bored, buy some other book. But if you want to understand Java, this book's for you.

Artificial Intelligence: A Modern Approach


Stuart Russell - 1994
    The long-anticipated revision of this best-selling text offers the most comprehensive, up-to-date introduction to the theory and practice of artificial intelligence. *NEW-Nontechnical learning material-Accompanies each part of the book. *NEW-The Internet as a sample application for intelligent systems-Added in several places including logical agents, planning, and natural language. *NEW-Increased coverage of material - Includes expanded coverage of: default reasoning and truth maintenance systems, including multi-agent/distributed AI and game theory; probabilistic approaches to learning including EM; more detailed descriptions of probabilistic inference algorithms. *NEW-Updated and expanded exercises-75% of the exercises are revised, with 100 new exercises. *NEW-On-line Java software. *Makes it easy for students to do projects on the web using intelligent agents. *A unified, agent-based approach to AI-Organizes the material around the task of building intelligent agents. *Comprehensive, up-to-date coverage-Includes a unified view of the field organized around the rational decision making pa

Cellular and Molecular Immunology


Abul K. Abbas - 1991
    Readers will continue to enjoy the current, concise, and straightforward approach to the field that made previous editions so popular. They'll understand the experimental observations that underlie the science of immunology at the molecular, cellular, and whole organism level-and explore the conclusions that can be drawn from those observations.The smart way to study!Elsevier titles with STUDENT CONSULT will help you master difficult concepts and study more efficiently in print and online! Perform rapid searches. Integrate bonus content from other disciplines. Download text to your handheld device. And a lot more. Each STUDENT CONSULT title comes with full text online, a unique image library, case studies, USMLE style questions, and online note-taking to enhance your learning experience.Highlights the implications of immunologic science for the management of human disease.Features over 365 full-color illustrations that highlight important processes and concepts, and bring the three-dimensional structures of molecules to life. Offers a wealth of reader-friendly features including major concepts highlighted in bold italics - at-a-glance boxes that present specialized information and explanations of current technological approaches - a wealth of tables that summarize key information - a glossary of terms - a CD Molecule Appendix that reflects the latest properties of known CD Molecules - an appendix on immunologic laboratory techniques - and more.Includes free access to a full-text online version, a downloadable collection of full-color images, sophisticated immunologic animations, integration links to bonus content in other STUDENT CONSULT titles, content clipping for handhelds, and more - all through the STUDENT CONSULT website at www.studentconsult.com.Incorporates the newest understandings of basic science as well as the newest research findings.Includes new information on the organization of lymphoid organs and mechanisms of innate immunity.Presents enhanced, more straightforward explanations of subjects such as of antigen-presenting cells and the biology of T cell activation.

Nonsense on Stilts: How to Tell Science from Bunk


Massimo Pigliucci - 2008
    More and more parents are refusing to vaccinate their children for fear it causes autism, though this link can been consistently disproved. And about 40 percent of Americans believe that the threat of global warming is exaggerated, despite near consensus in the scientific community that manmade climate change is real.Why do people believe bunk? And what causes them to embrace such pseudoscientific beliefs and practices? Noted skeptic Massimo Pigliucci sets out to separate the fact from the fantasy in this entertaining exploration of the nature of science, the borderlands of fringe science, and—borrowing a famous phrase from philosopher Jeremy Bentham—the nonsense on stilts. Presenting case studies on a number of controversial topics, Pigliucci cuts through the ambiguity surrounding science to look more closely at how science is conducted, how it is disseminated, how it is interpreted, and what it means to our society. The result is in many ways a “taxonomy of bunk” that explores the intersection of science and culture at large.No one—not the public intellectuals in the culture wars between defenders and detractors of science nor the believers of pseudoscience themselves—is spared Pigliucci’s incisive analysis. In the end, Nonsense on Stilts is a timely reminder of the need to maintain a line between expertise and assumption. Broad in scope and implication, it is also ultimately a captivating guide for the intelligent citizen who wishes to make up her own mind while navigating the perilous debates that will affect the future of our planet.

Journey to the Ants: A Story of Scientific Exploration


Bert Hölldobler - 1994
    Wilson's monumental treatise The Ants also was praised in the popular press and won a Pulitzer Prize. This overwhelming success attests to a fact long known and deeply felt by the authors: the infinite fascination of their tiny subjects. This fascination finds its full expression in Journey to the Ants, an overview of myrmecology that is also an eloquent tale of the authors' pursuit of these astonishing insects.Richly illustrated and delightfully written, Journey to the Ants combines autobiography and scientific lore to convey the excitement and pleasure the study of ants can offer. The authors interweave their personal adventures with the social lives of ants, building, from the first minute observations of childhood, a remarkable account of these abundant insects' evolutionary achievement. Accompanying Holldobler and Wilson, we peer into the colony to see how ants cooperate and make war, how they reproduce and bury their dead, how they use propaganda and surveillance, and how they exhibit a startlingly familiar ambivalence between allegiance and self-aggrandizement. This exotic tour of the entire range of formicid biodiversity - from social parasites to army ants, nomadic hunters, camouflaged huntresses, and energetic builders of temperature-controlled skyscrapers - opens out increasingly into natural history, intimating the relevance of ant life to human existence. A window on the world of ants as well as those who study them, this book will be a rich source of knowledge and pleasure for anyone who has ever stopped to wonder about the miniature yet immense civilization at our feet.

Calculus


Gilbert Strang - 1991
    The author has a direct style. His book presents detailed and intensive explanations. Many diagrams and key examples are used to aid understanding, as well as the application of calculus to physics and engineering and economics. The text is well organized, and it covers single variable and multivariable calculus in depth. An instructor's manual and student guide are available online at http: //ocw.mit.edu/ans7870/resources/Strang/....

Abnormal Psychology: An Integrative Approach


David H. Barlow - 2004
    Bundled (ISBN 9780534633622) textbook with InfoTrac CD-ROM.

Research Methods for the Behavioral Sciences


Frederick J. Gravetter - 2002
    Gravetter, and co-author Lori-Ann B. Forzano have written a text for research methods that helps you see how interesting and exciting experimental and non-experimental research can be. Inviting and conversational, RESEARCH METHODS FOR THE BEHAVIORAL SCIENCES, Third Edition, leads you through the research process from start to finish. The text opens with tips and strategies for generating research ideas, moves to selecting measures and participants, and then offers an examination of research strategy and design. This step-by-step approach emphasizes the decisions researchers must make at each stage of the process. The authors avoid a "cookbook" approach to the facts by linking terminology with applied concepts; their "lecture in a book" style emphasizes discussion and explanation of topics. Each chapter ends with a set of exercises and activities.

The Story of Stuff: How Our Obsession with Stuff is Trashing the Planet, Our Communities, and our Health—and a Vision for Change


Annie Leonard - 2010
    Leonard examines the “stuff” we use everyday, offering a galvanizing critique and steps for a changed planet.The Story of Stuff was received with widespread enthusiasm in hardcover, by everyone from Stephen Colbert to Tavis Smiley to George Stephanopolous on Good Morning America, as well as far-reaching print and blog coverage. Uncovering and communicating a critically important idea—that there is an intentional system behind our patterns of consumption and disposal—Annie Leonard transforms how we think about our lives and our relationship to the planet.From sneaking into factories and dumps around the world to visiting textile workers in Haiti and children mining coltan for cell phones in the Congo, Leonard, named one of Time magazine’s 100 environmental heroes of 2009, highlights each step of the materials economy and its actual effect on the earth and the people who live near sites like these.With curiosity, compassion, and humor, Leonard shares concrete steps for taking action at the individual and political level that will bring about sustainability, community health, and economic justice. Embraced by teachers, parents, churches, community centers, activists, and everyday readers, The Story of Stuff will be a long-lived classic.

What Is a Dog?


Raymond Coppinger - 2016
    But roaming the planet are four times as many dogs who are their own masters—neighborhood dogs, dump dogs, mountain dogs. They are dogs, not companions, and these dogs, like pigeons or squirrels, are highly adapted scavengers who have evolved to fit particular niches in the vicinity of humans. In What Is a Dog? experts on dog behavior Raymond and Lorna Coppinger present an eye-opening analysis of the evolution and adaptations of these unleashed dogs and what they can reveal about the species as a whole. Exploring the natural history of these animals, the Coppingers explain how the village dogs of Vietnam, India, Africa, and Mexico are strikingly similar. These feral dogs, argue the Coppingers, are in fact the truly archetypal dogs, nearly uniform in size and shape and incredibly self-sufficient. Drawing on nearly five decades of research, they show how dogs actually domesticated themselves in order to become such efficient scavengers of human refuse. The Coppingers also examine the behavioral characteristics that enable dogs to live successfully and to reproduce, unconstrained by humans, in environments that we ordinarily do not think of as dog friendly. Providing a fascinating exploration of what it actually means—genetically and behaviorally—to be a dog, What Is a Dog? will undoubtedly change the way any beagle or bulldog owner will reflect on their four-legged friend.

Principles of Neural Science


Eric R. Kandel - 1981
    It discusses neuroanatomy, cell and molecular mechanisms and signaling through a cognitive approach to behaviour. It features an expanded treatment of the nervous system, neurological and psychiatric diseases and perception.

Concepts of Genetics


William S. Klug - 2005
    The authors capture students' interest with up-to-date coverage of cutting edge topics and research. This text will help students connect the science of genetics to the issues of today through interesting and thought-provoking applications. The sixth edition boasts the next generation of media integration including Gen CD-X (student CD-ROM and Companion Website).