Five months earlier, logger-turned-activist Grant Hadwin had plunged naked into a river in British Columbia's Queen Charlotte Islands, towing a chainsaw. When his night's work was done, a unique Sitka spruce, 165 feet tall and covered with luminous golden needles, teetered on its stump. Two days later it fell.As vividly as John Krakauer puts readers on Everest, John Vaillant takes us into the heart of North America's last great forest.

    Dr. Cassandra Quave is a leading medical ethnobotanist--someone who identifies and studies plants that may be able to treat antimicrobial resistance and other threatening illnesses-- helping to provide clues for the next generation of advanced medicines. In The Plant Hunter, Dr. Quave weaves together science, botany, and memoir to tell us the extraordinary story of her own journey. Traveling by canoe, ATV, mule, airboat, and on foot, she has conducted field research in the flooded forests of the remote Amazon, the murky swamps of southern Florida, the rolling hills of central Italy, isolated mountaintops in Albania and Kosovo, and volcanic isles arising out of the Mediterranean—all in search of natural compounds, long-known to traditional healers, that could help save us all from the looming crisis of untreatable superbugs. And as a person born with multiple congenital defects of her skeletal system, she's done it all with just one leg. Filled with grit, tragedy, triumph, awe, and scientific discovery, her story illuminates how the path forward for medical discovery may be found in nature's oldest remedies.Plants are the basis for an array of lifesaving and health-improving medicines we all now take for granted. Ever taken an aspirin? Thank a willow tree for that. What about life-saving medicines for malaria? Some of those are derived from cinchona and wormwood. No one knows this better than Dr. Quave, and her story and research will open your eyes to the wonder of the natural world around you.

    Afflicted by epidemics and their consequences from the 1770s until the 1940s, Alaska Natives are still feeling traumatic effects in the form of alcoholism, suicide and violence. The wholeness of a society that maintained health and vigor for thousands of years was broken by the Great Death and has not been repaired by anti-poverty programs, welfare, government-sponsored health and education programs, or prohibition laws. Through bitter experience, Napoleon, a Yupik Eskimo, has acquired clarity in understanding the roots and tenacity of these problems, articulating them clearly and powerfully. But more than this, he offers a message of hope pointing the way toward cultural revitalization that can begin now. The steps in the journey to reclaiming health and well-being depends on communicating the sorrow and loss and embracing a new way of thinking about the problem. While there is much work to be done, this work shows a way that individuals and villages can transform the Great Death into new life.Napoleon’s narrative is followed by commentaries from elders and academics concerned with understanding and overcoming the challenges that Alaska Natives face today.

    At just two years old, Nic experienced a searing pain that signaled the awakening of a new and deadly disease, one that would hurl Nic and his family up against the limits of modern medicine. For years, through false starts and failed cures, Nic holds on to life, buoyed up by his mother’s fierce drive to get him the care he needs. But when even the world’s experts are stumped by Nic’s illness, his doctors come up with a radical, long-shot plan: a step into the unknown. The next major scientific frontier, following the completion of the Human Genome Project, was to figure out how to use our new knowledge to save lives—to bring genomic or personalized medicine into reality. It’s a quest that is undertaken by researchers around the world. But it is only when geneticist Howard Jacob hears about young Nic that the finish line finally comes into sight: It’s no longer a race to make history. It’s a race to save this boy’s life. One in a Billion is an unforgettable tale of the lives that converged to launch a medical revolution. As pioneering geneticist Mary-Claire King pronounced upon learning Nic’s story: “It was as if one had heard about Case Zero of AIDS and the cure, all at once.”