But how did America become "one nation, indivisible"? What unified a growing number of disparate states into the modern country we recognize today? In this monumental history, Simon Winchester addresses these questions, bringing together the breathtaking achievements that helped forge and unify America and the pioneers who have toiled fearlessly to discover, connect, and bond the citizens and geography of the U.S.A. from its beginnings.Winchester follows in the footsteps of America's most essential explorers, thinkers, and innovators, including Lewis and Clark and their Corps of Discovery Expedition to the Pacific Coast, the builders of the first transcontinental telegraph, and the powerful civil engineer behind the Interstate Highway System. He treks vast swaths of territory, from Pittsburgh to Portland; Rochester to San Francisco; Truckee to Laramie; Seattle to Anchorage, introducing these fascinating men and others-some familiar, some forgotten, some hardly known-who played a pivotal role in creating today's United States. Throughout, he ponders whether the historic work of uniting the States has succeeded, and to what degree.Featuring 32 illustrations throughout the text, The Men Who United the States is a fresh, lively, and erudite look at the way in which the most powerful nation on earth came together, from one of our most entertaining, probing, and insightful observers.

    The depth below is hot, much warmer than the surface and this book tunnels down through the geological layers, meeting the creatures that dwell in darkness, real and fictional -- rats and eels, monsters and ghosts. There is a bronze-age trackway under the Isle of Dogs, Wren found Anglo-Saxon graves under St Paul's, and the monastery of Whitefriars lies beneath Fleet Street. In Kensal Green cemetery there was a hydraulic device to lower bodies into the catacombs below -- "Welcome to the lower depths". A door in the plinth of statue of Boadicea on Westminster Bridge leads to a huge tunnel, packed with cables -- gas, water, telephone. When the Metropolitan Line was opened in 1864 the guards asked for permission to grow beards to protect themselves against the sulphurous fumes, and called their engines by the names of tyrants -- Czar, Kaiser, Mogul -- and even Pluto, god of the underworld.Going under London is to penetrate history, to enter a hidden world. "The vastness of the space, a second earth," writes Peter Ackroyd, "elicits sensations of wonder and of terror. It partakes of myth and dream in equal measure."

    And yet she is often confounded by the cases she describes in her column: unexpected collections of symptoms that she and other physicians struggle to diagnose.A twenty-eight-year-old man, vacationing in the Bahamas for his birthday, tries some barracuda for dinner. Hours later, he collapses on the dance floor with crippling stomach pains. A middle-aged woman returns to her doctor, after visiting two days earlier with a mild rash on the back of her hands. Now the rash has turned purple and has spread across her entire body in whiplike streaks. A young elephant trainer in a traveling circus, once head-butted by a rogue zebra, is suddenly beset with splitting headaches, as if someone were "slamming a door inside his head."In each of these cases, the path to diagnosis--and treatment--is winding, sometimes frustratingly unclear. Dr. Sanders shows how making the right diagnosis requires expertise, painstaking procedure, and sometimes a little luck. Intricate, gripping, and full of twists and turns, Diagnosis puts readers in the doctor's place. It lets them see what doctors see, feel the uncertainty they feel--and experience the thrill when the puzzle is finally solved.

    She shows how both Presidents Hoover and Roosevelt failed to understand the prosperity of the 1920s and heaped massive burdens on the country that more than offset the benefit of New Deal programs.

    As the 1790s began, a fragile America teetered on the brink of oblivion, Russia towered as a vast imperial power, and France plunged into revolution. But in contrast to the way conventional histories tell it, none of these remarkable events occurred in isolation.Now, for the first time, acclaimed historian Jay Winik masterfully illuminates how their fates combined in one extraordinary moment to change the course of civilization. A sweeping, magisterial drama featuring the richest cast of characters ever to walk upon the world stage, including Washington, Jefferson, Louis XVI, Robespierre, and Catherine the Great, The Great Upheaval is a gripping, epic portrait of this tumultuous decade that will forever transform the way we see America's beginnings and our world

    -- Charles Francis Adams John Adams, Thomas Jefferson, Benjamin Franklin -- these are the names we typically associate with the American Revolution. But was American History solely written by men? Were there no influential women? No women who had an impact on the founding of America in its crucial, formative years, in its fight for independence? Indeed, there were -- although their contributions have been overlooked or ignored for over two hundred years. Until now. Glory, Passion, and Principle is an extraordinary journey through revolutionary America as seen from a woman's perspective. Here are the lesser-known stories of eight influential females who fought for freedom -- for their country and themselves -- at all costs. Whether advising prominent male leaders in political theory (Abigail Adams), using their pens as swords (Phillis Wheatley, Mercy Otis Warren), acting as military spies (Sybil Ludington, Lydia Darragh), or going to battle (Molly Pitcher, Deborah Sampson, Nancy Ward), these women broke free of the limitations imposed upon them, much as our forefathers did by resisting British rule upon American soil...and laying the groundwork for the United States as we know it today.

    Linda Burfield Hazzard. It was supposed to be a holiday for the two sisters. But within a month of arriving at what the locals called Starvation Heights, the women were emaciated shadows of their former selves, waiting for death. They were not the first victims of Linda Hazzard, a quack doctor of extraordinary evil and greed who would stop at nothing short of murder to achieve her ambitions. As their jewelry disappeared and forged bank drafts began transferring their wealth to Hazzard’s accounts, Dora Williamson sent a last desperate plea to a friend in Australia, begging her to save them from the brutal treatments and lonely isolation of Starvation Heights.In this true story—a haunting saga of medical murder set in an era of steamships and gaslights—Gregg Olsen reveals one of the most unusual and disturbing criminal cases in American history.

    In setting up his household he took Tobias Lear, his celebrated secretary, and nine slaves, including Ona Judge, about which little has been written. As he grew accustomed to Northern ways, there was one change he couldn’t get his arms around: Pennsylvania law required enslaved people be set free after six months of residency in the state. Rather than comply, Washington decided to circumvent the law. Every six months he sent the slaves back down south just as the clock was about to expire.Though Ona Judge lived a life of relative comfort, the few pleasantries she was afforded were nothing compared to freedom, a glimpse of which she encountered first-hand in Philadelphia. So, when the opportunity presented itself one clear and pleasant spring day in Philadelphia, Judge left everything she knew to escape to New England. Yet freedom would not come without its costs.At just twenty-two-years-old, Ona became the subject of an intense manhunt led by George Washington, who used his political and personal contacts to recapture his property.Impeccably researched, historian Erica Armstrong Dunbar weaves a powerful tale and offers fascinating new scholarship on how one young woman risked it all to gain freedom from the famous founding father.

    His passing on March 6, 1900, would have been unremarkable if a city health officer hadn’t noticed a swollen black lymph node on his groin—a sign of bubonic plague. Empowered by racist pseudoscience, officials rushed to quarantine Chinatown while doctors examined Wong’s tissue for telltale bacteria. If the devastating disease was not contained, San Francisco would become the American epicenter of an outbreak that had already claimed ten million lives worldwide.To local press, railroad barons, and elected officials, such a possibility was inconceivable—or inconvenient. As they mounted a cover-up to obscure the threat, ending the career of one of the most brilliant scientists in the nation in the process, it fell to federal health officer Rupert Blue to save a city that refused to be rescued. Spearheading a relentless crusade for sanitation, Blue and his men patrolled the squalid streets of fast-growing San Francisco, examined gory black buboes, and dissected diseased rats that put the fate of the entire country at risk.In the tradition of Erik Larson and Steven Johnson, Randall spins a spellbinding account of Blue’s race to understand the disease and contain its spread—the only hope of saving San Francisco, and the nation, from a gruesome fate.

    Bennet Omalu, the pathologist who made one of the most significant medical discoveries of the twenty-first century, a discovery that challenges the existence of America’s favorite sport and puts Omalu in the crosshairs of football’s most powerful corporation: the NFL. Jeanne Marie Laskas first met the young forensic pathologist Dr. Bennet Omalu in 2009, while reporting a story for GQ that would go on to inspire the movie Concussion. Omalu told her about a day in September 2002, when, in a dingy morgue in downtown Pittsburgh, he picked up a scalpel and made a discovery that would rattle America in ways he’d never intended. Omalu was new to America, chasing the dream, a deeply spiritual man escaping the wounds of civil war in Nigeria. The body on the slab in front of him belonged to a fifty-year-old named Mike Webster, aka “Iron Mike,” a Hall of Fame center for the Pittsburgh Steelers, one of the greatest ever to play the game. After retiring in 1990, Webster had suffered a dizzyingly steep decline. Toward the end of his life, he was living out of his van, tasering himself to relieve his chronic pain, and fixing his rotting teeth with Super Glue. How did this happen?, Omalu asked himself. How did a young man like Mike Webster end up like this? The search for answers would change Omalu’s life forever and put him in the crosshairs of one of the most powerful corporations in America: the National Football League. What Omalu discovered in Webster’s brain—proof that Iron Mike’s mental deterioration was no accident but a disease caused by blows to the head that could affect everyone playing the game—was the one truth the NFL wanted to ignore.   Taut, gripping, and gorgeously told, Concussion is the stirring story of one unlikely man’s decision to stand up to a multibillion-dollar colossus, and to tell the world the truth.  Advance praise for Concussion “A gripping medical mystery and a dazzling portrait of the young scientist no one wanted to listen to . . . a fabulous, essential read.”—Rebecca Skloot, author of The Immortal Life of Henrietta Lacks“The story of Dr. Bennet Omalu’s battle against the NFL is classic David and Goliath stuff, and Jeanne Marie Laskas—one of my favorite writers on earth—makes it as exciting as any great courtroom or gridiron drama. A riveting, powerful human tale—and a master class on how to tell a story.”—Charles Duhigg, author of The Power of Habit   “Bennet Omalu forced football to reckon with head trauma. The NFL doesn’t want you to hear his story, but Jeanne Marie Laskas makes it unforgettable. This book is gripping, eye-opening, and full of heart.”—Emily Bazelon, author of Sticks and Stones

    For the seventeenth-century aristocratic Frenchman, it meant changing his shirt once a day, using perfume to obliterate both his own aroma and everyone else’s, but never immersing himself in – horrors! – water. By the early 1900s, an extraordinary idea took hold in North America – that frequent bathing, perhaps even a daily bath, was advisable. Not since the Roman Empire had people been so clean, and standards became even more extreme as the millennium approached. Now we live in a deodorized world where germophobes shake hands with their elbows and where sales of hand sanitizers, wipes and sprays are skyrocketing.The apparently routine task of taking up soap and water (or not) is Katherine Ashenburg’s starting point for a unique exploration of Western culture, which yields surprising insights into our notions of privacy, health, individuality, religion and sexuality.Ashenburg searches for clean and dirty in plague-ridden streets, medieval steam baths, castles and tenements, and in bathrooms of every description. She reveals the bizarre rescriptions of history’s doctors as well as the hygienic peccadilloes of kings, mistresses, monks and ordinary citizens, and guides us through the twists and turns to our own understanding of clean, which is no more rational than the rest. Filled with amusing anecdotes and quotations from the great bathers of history, The Dirt on Clean takes us on a journey that is by turns intriguing, humorous, startling and not always for the squeamish. Ashenburg’s tour of history’s baths and bathrooms reveals much about our changing and most intimate selves – what we desire, what we ignore, what we fear, and a significant part of who we are.

    Yet despite a century of medical progress, viral and bacterial disasters continue to take us by surprise, inciting panic and dominating news cycles. From the Spanish flu to the 1924 outbreak of pneumonic plague in Los Angeles to the 1930 “parrot fever” pandemic, through the more recent SARS, Ebola, and Zika epidemics, the last one hundred years have been marked by a succession of unanticipated pandemic alarms.In The Pandemic Century, a lively account of scares both infamous and less known, Mark Honigsbaum combines reportage with the history of science and medical sociology to artfully reconstruct epidemiological mysteries and the ecology of infectious diseases. We meet dedicated disease detectives, obstructive or incompetent public health officials, and brilliant scientists often blinded by their own knowledge of bacteria and viruses. We also see how fear of disease often exacerbates racial, religious, and ethnic tensions—even though, as the epidemiologists Malik Peiris and Yi Guan write, “‘nature’ remains the greatest bioterrorist threat of all.”Like man-eating sharks, predatory pathogens are always present in nature, waiting to strike; when one is seemingly vanquished, others appear in its place. These pandemics remind us of the limits of scientific knowledge, as well as the role that human behavior and technologies play in the emergence and spread of microbial diseases.

    The emotional, incredible true story of Neil White, a man who discovers the secret to happiness, leading a fulfilling life, and the importance of fatherhood in the most unlikely of places—the last leper colony in the continental United States.

    Working in the kitchens of the upper class, she left a trail of disease in her wake, until one enterprising and ruthless “medical engineer” proposed the inconceivable notion of the “asymptomatic carrier”—and from then on Mary Mallon was a hunted woman. In order to keep New York’s citizens safe from Mallon, the Department of Health sent her to North Brother Island where she was kept in isolation from 1907-1910. She was released under the condition that she never work as a cook again. Yet for Mary—spoiled by her status and income and genuinely passionate about cooking—most domestic and factory jobs were heinous. She defied the edict.Bringing early twentieth-century New York alive—the neighborhoods, the bars, the park being carved out of upper Manhattan, the emerging skyscrapers, the boat traffic—Fever is as fiercely compelling as Typhoid Mary herself, an ambitious retelling of a forgotten life. In the hands of Mary Beth Keane, Mary Mallon becomes an extraordinarily dramatic, vexing, sympathetic, uncompromising, and unforgettable character.

    It could be an oddball researcher’s genius insight, a catalyzing moment in geopolitical history, a new breakthrough technology, or an unexpected but welcome side effect discovered during clinical trials. Piece together these stories, as Thomas Hager does in this remarkable, century-spanning history, and you can trace the evolution of our culture and the practice of medicine.  ​Beginning with opium, the “joy plant,” which has been used for 10,000 years, Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.