Markel writes of the physical and emotional damage caused by the then-heralded wonder drug, and how each man ultimately changed the world in spite of it—or because of it. One became the father of psychoanalysis; the other, of modern surgery. Both men were practicing medicine at the same time in the 1880s: Freud at the Vienna General Hospital, Halsted at New York’s Bellevue Hospital. Markel writes that Freud began to experiment with cocaine as a way of studying its therapeutic uses—as an antidote for the overprescribed morphine, which had made addicts of so many, and as a treatment for depression.  Halsted, an acclaimed surgeon even then, was curious about cocaine’s effectiveness as an anesthetic and injected the drug into his arm to prove his theory. Neither Freud nor Halsted, nor their colleagues, had any idea of the drug’s potential to dominate and endanger their lives. Addiction as a bona fide medical diagnosis didn’t even exist in the elite medical circles they inhabited.  In An Anatomy of Addiction, Markel writes about the life and work of each man, showing how each came to know about cocaine; how Freud found that the drug cured his indigestion, dulled his aches, and relieved his depression. The author writes that Freud, after a few months of taking the magical drug, published a treatise on it, Über Coca, in which he described his “most gorgeous excitement.” The paper marked a major shift in Freud’s work: he turned from studying the anatomy of the brain to exploring the human psyche.  Halsted, one of the most revered of American surgeons, became the head of surgery at the newly built Johns Hopkins Hospital and then professor of surgery, the hospital’s most exalted position, committing himself repeatedly to Butler Hospital, an insane asylum, to withdraw from his out-of control cocaine use.  Halsted invented modern surgery as we know it today: devising new ways to safely invade the body in search of cures and pioneering modern surgical techniques that controlled bleeding and promoted healing. He insisted on thorough hand washing, on scrub-downs and whites for doctors and nurses, on sterility in the operating room—even inventing the surgical glove, which he designed and had the Goodyear Rubber Company make for him—accomplishing all of this as he struggled to conquer his unyielding desire for cocaine.  An Anatomy of Addiction tells the tragic and heroic story of each man, accidentally struck down in his prime by an insidious malady: tragic because of the time, relationships, and health cocaine forced each to squander; heroic in the intense battle each man waged to overcome his affliction as he conquered his own world with his visionary healing gifts. Here is the full story, long overlooked, told in its rich historical context.

    In Elephants on Acid, Boese details the results of this scientific trial, as well as answers to the questions: Why can't people tickle themselves? Would the average dog summon help in an emergency? Will babies instinctually pick a well-balanced diet? Is it possible to restore life to the dead? Read on to find out...

    A murder. A mystery.The most important person on the scene? The forensic scientist. And yet the intricate details of their work remains a mystery to most of us. Silent Witnesses looks at the history of forensic science over the last two centuries, during which time a combination of remarkable intuition, painstaking observation and leaps in scientific knowledge have developed this fascinating branch of detection. Throwing open the casebook, it introduces us to such luminaries as 'The Wizard of Berkeley' Edward Heinrich, who is credited with having solved over 2000 crimes, and Alphonse Bertillon, the French scientist whose guiding principle 'no two individuals share the same characteristics' became the core of identification. Along the way, it takes us to India and Australia, Columbia and China, Russia, France, Germany, Spain and Italy. And it proves that, in order to solve ever more complicated cases, science must always stay one step ahead of the killer.

    Flow spans its fascinating, occasionally wacky and sometimes downright scary story: from mikvahs (ritual cleansing baths) to menopause, hysteria to hysterectomies—not to mention the Pill, cramps, the history of underwear, and the movie about puberty they showed you in 5th grade. Flow answers such questions as: What’s the point of getting a period? What did women do before pads and tampons? What about new drugs that promise to end periods—a hot idea or not? Sex during your period: gross or a turn-on? And what’s normal, anyway?  With color reproductions of (campy) historical ads and early (excruciating) femcare devices, it also provides a fascinating (and mind-boggling) gallery of this complex, personal and uniquely female process. As irreverent as it is informative, Flow gives an everyday occurrence its true props – and eradicates the stigma placed on it for centuries.

    Drawing on momentous (yet dimly remembered) historical epidemics, contemporary analyses, and cutting-edge research from a range of scientific disciplines, bestselling author, physician, sociologist, and public health expert Nicholas A. Christakis explores what it means to live in a time of plague—an experience that is paradoxically uncommon to the vast majority of humans who are alive, yet deeply fundamental to our species.Unleashing new divisions in our society as well as opportunities for cooperation, this 21st-century pandemic has upended our lives in ways that will test, but not vanquish, our already frayed collective culture. Featuring new, provocative arguments and vivid examples ranging across medicine, history, sociology, epidemiology, data science, and genetics, Apollo's Arrow envisions what happens when the great force of a deadly germ meets the enduring reality of our evolved social nature.

    But armies have developed sophisticated ways of overcoming this instinctive aversion. And contemporary civilian society, particularly the media, replicates the army's conditioning techniques, and, according to Lt. Col. Dave Grossman's thesis, is responsible for our rising rate of murder among the young.Upon its initial publication, On Killing was hailed as a landmark study of the techniques the military uses to overcome the powerful reluctance to kill, of how killing affects soldiers, and of the societal implications of escalating violence. Now, Grossman has updated this classic work to include information on 21st-century military conflicts, recent trends in crime, suicide bombings, school shootings, and more. The result is a work certain to be relevant and important for decades to come.

    In The Poisoner's Handbook Blum draws from highly original research to track the fascinating, perilous days when a pair of forensic scientists began their trailblazing chemical detective work, fighting to end an era when untraceable poisons offered an easy path to the perfect crime. Drama unfolds case by case as the heroes of The Poisoner's Handbook—chief medical examiner Charles Norris and toxicologist Alexander Gettler—investigate a family mysteriously stricken bald, Barnum and Bailey's Famous Blue Man, factory workers with crumbling bones, a diner serving poisoned pies, and many others. Each case presents a deadly new puzzle and Norris and Gettler work with a creativity that rivals that of the most imaginative murderer, creating revolutionary experiments to tease out even the wiliest compounds from human tissue. Yet in the tricky game of toxins, even science can't always be trusted, as proven when one of Gettler's experiments erroneously sets free a suburban housewife later nicknamed "America's Lucretia Borgia" to continue her nefarious work. From the vantage of Norris and Gettler's laboratory in the infamous Bellevue Hospital it becomes clear that killers aren't the only toxic threat to New Yorkers. Modern life has created a kind of poison playground, and danger lurks around every corner. Automobiles choke the city streets with carbon monoxide; potent compounds, such as morphine, can be found on store shelves in products ranging from pesticides to cosmetics. Prohibition incites a chemist's war between bootleggers and government chemists while in Gotham's crowded speakeasies each round of cocktails becomes a game of Russian roulette. Norris and Gettler triumph over seemingly unbeatable odds to become the pioneers of forensic chemistry and the gatekeepers of justice during a remarkably deadly time. A beguiling concoction that is equal parts true crime, twentieth-century history, and science thriller, The Poisoner's Handbook is a page-turning account of a forgotten New York.

    Reay Tannahill's scholarly, yet accessible study ranges from the earliest form of contraception (one Egyptian concoction included crocodile dung) to some latter- day misconceptions about it- like the men who joined their lovers in taking the pill 'just to be on the safe side.' It surveys all manner of sexual practice, preference and position (the acrobatic 'wheelbarrow' position, the strenuous 'hovering butterflies' position...) and draws on souces as diverse as THE ADMIRABLE DISCOURSES OF THE PLAIN GIRL, the EXHIBTION OF FEMALE FLAGELLANTS, IMPORTANT MATTERS OF THE JADE CHAMBER and THE ROMANCE OF CHASTISEMENT. Whether writing on androgyny, courtly love, flagellation or zoophilia, Turkish eunuch's Greek dildoes, Taoist sex manuals or Japanses geisha girls, Reay Tannahill is consistently enlightening and entertaining.

    In this updated edition of the classic work, Mark Pendergrast reviews the dramatic changes in coffee culture over the past decade, from the disastrous “Coffee Crisis” that caused global prices to plummet to the rise of the Fair Trade movement and the “third-wave” of quality-obsessed coffee connoisseurs. As the scope of coffee culture continues to expand, Uncommon Grounds remains more than ever a brilliantly entertaining guide to the currents of one of the world’s favorite beverages.

    The Lady and Her Monsters by Roseanne Motillo brings to life the fascinating times, startling science, and real-life horrors behind Mary Shelley’s gothic masterpiece, Frankenstein.Montillo recounts how—at the intersection of the Romantic Age and the Industrial Revolution—Shelley’s Victor Frankenstein was inspired by actual scientists of the period: curious and daring iconoclasts who were obsessed with the inner workings of the human body and how it might be reanimated after death.With true-life tales of grave robbers, ghoulish experiments, and the ultimate in macabre research—human reanimation—The Lady and Her Monsters is a brilliant exploration of the creation of Frankenstein, Mary Shelley’s horror classic.

    With his trademark fearlessness and bracing sense of humor, Schechter digs deep into a wealth of sources to unearth a treasure trove of surprising facts, amusing anecdotes, practical information, and timeless wisdom about that undiscovered country to which we will all one day travel. Topics include• Death anxiety–is your fear of death normal or off the scale? • You can’t take it with you . . . or can you? Wacky wills and bizarre bequests• The hospice experience–going out in comfort and style• Deathbed and funeral etiquette–how to help the dying and mourn the dead with dignity• Death on demand–why the right-to-die movement may be the next big thing• “Good-bye everybody”–famous last words• The embalmer’s art–all dressed up and nowhere to go• Behind the scenes at your local funeral home• Alternative burial choices–from coral reefs to outer spaceFrom the cold, hard facts of death to lessons in the art of dying well, from what happens in the body’s last living moments to what transpires in the ground or in the furnace, from near-death experiences to speculation on the afterlife, The Whole Death Catalog leaves no gravestone unturned.

    Into this crisis stepped Walter Freeman, M.D., who saw a solution in lobotomy, a brain operation intended to reduce the severity of psychotic symptoms. Drawing on Freeman’s documents and interviews with Freeman's family, Jack El-Hai takes a penetrating look at the life and work of this complex scientific genius.The Lobotomist explores one of the darkest chapters of American medicine: the desperate attempt to treat the hundreds of thousands of psychiatric patients in need of help during the middle decades of the twentieth century. Into this crisis stepped Walter Freeman, M.D., who saw a solution in lobotomy, a brain operation intended to reduce the severity of psychotic symptoms. Although many patients did not benefit from the thousands of lobotomies Freeman performed, others believed their lobotomies changed them for the better. Drawing on a rich collection of documents Freeman left behind and interviews with Freeman's family, Jack El-Hai takes a penetrating look into the life of this complex scientific genius and traces the physician's fascinating life and work.

    In the last fifty years, we've zoomed through radically different forms of communication, from typewriters to tablet computers, text messages to tweets. We generate more and more words with each passing day. Hiding in that deluge of language are amazing insights into who we are, how we think, and what we feel.In The Secret Life of Pronouns, social psychologist and language expert James W. Pennebaker uses his groundbreaking research in computational linguistics-in essence, counting the frequency of words we use-to show that our language carries secrets about our feelings, our self-concept, and our social intelligence. Our most forgettable words, such as pronouns and prepositions, can be the most revealing: their patterns are as distinctive as fingerprints.Using innovative analytic techniques, Pennebaker X-rays everything from Craigslist advertisements to the Federalist Papers-or your own writing, in quizzes you can take yourself-to yield unexpected insights. Who would have predicted that the high school student who uses too many verbs in her college admissions essay is likely to make lower grades in college? Or that a world leader's use of pronouns could reliably presage whether he led his country into war? You'll learn why it's bad when politicians use "we" instead of "I," what Lady Gaga and William Butler Yeats have in common, and how Ebenezer Scrooge's syntax hints at his self-deception and repressed emotion. Barack Obama, Sylvia Plath, and King Lear are among the figures who make cameo appearances in this sprightly, surprising tour of what our words are saying-whether we mean them to or not.

    Frances E. Jensen, a mother, teacher, researcher, and internationally known expert in neurology, introduces us to the mystery and magic of the teen brain. One of the first books to focus exclusively on the neurological development of adolescents, The Teenage Brain presents new findings, dispels widespread myths, and provides practical suggestions for negotiating this difficult and dynamic life stage for both adults and adolescents.Interweaving easy-to-follow scientific data with anecdotes drawn from her experiences as a parent, clinician, and public speaker, Dr. Jensen explores adolescent brain functioning and development, including learning and memory, and investigates the impact of influences such as drugs, multitasking, sleep, and stress. The Teenage Brain reveals how: Adolescents may not be as resilient to the effects of drugs as we previously thought. Occasional use of marijuana has been shown to cause lingering memory problems, and long-term use can affect later adulthood I.Q. Multi-tasking causes divided attention and can reduce learning ability. Emotionally stressful situations in adolescence can have permanent effects on mental health, and may lead to higher risk for certain neuropsychiatric disorders such as depression.Rigorous yet accessible, warm yet direct, The Teenage Brain sheds new light on young adults, and provides practical suggestions for how parents, schools, and even the legal system can better help them during this crucial period.

    In nineteenth-century New England another sort of vampire was relentlessly ravishing the populace, or so it was believed by many rural communities suffering the plague of tuberculosis. Indeed, as this fascinating book shows, the vampire of folk superstition figures significantly in the attempt of early Americans to reasonably explain and vanquish the dreaded affliction then known as consumption. In gripping narrative detail, folklorist Michael E. Bell reconstructs a distant world, where on March 17, 1892, three corpses were exhumed from a Rhode Island cemetery. One of them, Mercy Brown, who had succumbed to consumption, appeared to have turned over in her grave. Mercy's family cut out her heart, which still held clots of blood, burned it on a nearby rock, and fed the ashes to her ailing brother. To Mercy's community she had become a vampire living a spectral existence and consuming the vitality of her siblings. From documents written as early as 1790 to a recent conversation with a descendant of Mercy Brown, Bell investigates twenty cases in which the vampiric dead were exhumed to save the ailing living. He also explores a widespread folk tradition that has survived generations, as ordinary people today strive to battle extraordinary diseases like Ebola or AIDS with a deeply rooted belief in their power to heal themselves. "Bell's absorbing account is ... a major contribution to the study of New England folk beliefs."—Boston Globe "Filled with ghostly tales, glowing corpses, rearranged bones, visits to hidden graveyards.... This is a marvelous book."—Providence Journal