Months later, several health professionals faced criminal allegations that they deliberately injected numerous patients with drugs to hasten their deaths. Five Days at Memorial, the culmination of six years of reporting, unspools the mystery of what happened in those days, bringing the reader into a hospital fighting for its life and into a conversation about the most terrifying form of health care rationing.In a voice at once involving and fair, masterful and intimate, Fink exposes the hidden dilemmas of end-of-life care and reveals just how ill-prepared we are in America for the impact of large-scale disasters—and how we can do better. A remarkable book, engrossing from start to finish, Five Days at Memorial radically transforms your understanding of human nature in crisis.

    Acclaimed historian G. J. Meyer reveals the flesh-and-bone reality in all its wild excess.In 1485, young Henry Tudor, whose claim to the throne was so weak as to be almost laughable, crossed the English Channel from France at the head of a ragtag little army and took the crown from the family that had ruled England for almost four hundred years. Half a century later his son, Henry VIII, desperate to rid himself of his first wife in order to marry a second, launched a reign of terror aimed at taking powers no previous monarch had even dreamed of possessing. In the process he plunged his kingdom into generations of division and disorder, creating a legacy of blood and betrayal that would blight the lives of his children and the destiny of his country.The boy king Edward VI, a fervent believer in reforming the English church, died before bringing to fruition his dream of a second English Reformation. Mary I, the disgraced daughter of Catherine of Aragon, tried and failed to reestablish the Catholic Church and produce an heir. And finally came Elizabeth I, who devoted her life to creating an image of herself as Gloriana the Virgin Queen but, behind that mask, sacrificed all chance of personal happiness in order to survive.  The Tudors weaves together all the sinners and saints, the tragedies and triumphs, the high dreams and dark crimes, that reveal the Tudor era to be, in its enthralling, notorious truth, as momentous and as fascinating as the fictions audiences have come to love.

    Judy Melinek began her training as a New York City forensic pathologist. With her husband T.J. and their toddler Daniel holding down the home front, Judy threw herself into the fascinating world of death investigation, performing autopsies, investigating death scenes, counseling grieving relatives. Working Stiff chronicles Judy's two years of training, taking readers behind the police tape of some of the most harrowing deaths in the Big Apple, including a firsthand account of the events of September 11, the subsequent anthrax bio-terrorism attack, and the disastrous crash of American Airlines flight 587.Lively, action-packed, and loaded with mordant wit, Working Stiff offers a firsthand account of daily life in one of America's most arduous professions, and the unexpected challenges of shuttling between the domains of the living and the dead. The body never lies, and through the murders, accidents, and suicides that land on her table, Dr. Melinek lays bare the truth behind the glamorized depictions of autopsy work on shows like CSI and Law and Order to reveal the secret story of the real morgue.

    Seven months later, after joining a party of emigrants led by George Donner, they reached the Sierra Nevada Mountains as the first heavy snows of the season closed the pass ahead of them. In early December, starving and desperate, Sarah and fourteen others set out for California on snowshoes and, over the next thirty-two days, endured almost unfathomable hardships and horrors. In this gripping narrative, Daniel James Brown sheds new light on one of the most infamous events in American history. Following every painful footstep of Sarah's journey with the Donner Party, Brown produces a tale both spellbinding and richly informative.

    From its dawn in the 1660s to its twilight in the 1960s, Cliveden was an emblem of elite misbehaviour and intrigue. Conceived by the Duke of Buckingham as a retreat for his scandalous affair with Anna-Maria, Countess of Shrewsbury, the house later served as the backdrop for the Profumo Affair, which would bring down a government and change the course of British history.In the three hundred years between the Countess and Christine Keeler, the house was occupied by a dynasty of remarkable women: Elizabeth Villiers, an intellectual who brokered the rise and fall of governments; Augusta of Saxe-Gotha, a minor German royal who almost became queen of England; Harriet Duchess of Sutherland, the glittering society hostess turned political campaigner; and Nancy Astor, the consummate controversialist who became the first woman to take a seat in parliament. Under the direction of these women, Cliveden provided a stage for political plots and artistic premieres, hosted grieving monarchs and republican radicals, was idealised as a family home, and maligned as a threat to national security.The Mistresses of Cliveden is by turns a historical epic, a political thriller, a family drama, and an intimate history of the relationships between people and place. Above all, it is a story about sex and power, and the ways in which exceptional women have evaded, exploited, and confronted the expectations of their times.

    The age-old disease spread swiftly through an increasingly interconnected American landscape: from southern tobacco plantations to the dense immigrant neighborhoods of northern cities to far-flung villages on the edges of the nascent American empire. In Pox, award-winning historian Michael Willrich offers a gripping chronicle of how the nation's continentwide fight against smallpox launched one of the most important civil liberties struggles of the twentieth century.At the dawn of the activist Progressive era and during a moment of great optimism about modern medicine, the government responded to the deadly epidemic by calling for universal compulsory vaccination. To enforce the law, public health authorities relied on quarantines, pesthouses, and "virus squads"-corps of doctors and club-wielding police. Though these measures eventually contained the disease, they also sparked a wave of popular resistance among Americans who perceived them as a threat to their health and to their rights.At the time, anti-vaccinationists were often dismissed as misguided cranks, but Willrich argues that they belonged to a wider legacy of American dissent that attended the rise of an increasingly powerful government. While a well-organized anti-vaccination movement sprang up during these years, many Americans resisted in subtler ways-by concealing sick family members or forging immunization certificates. Pox introduces us to memorable characters on both sides of the debate, from Henning Jacobson, a Swedish Lutheran minister whose battle against vaccination went all the way to the Supreme Court, to C. P. Wertenbaker, a federal surgeon who saw himself as a medical missionary combating a deadly-and preventable-disease.As Willrich suggests, many of the questions first raised by the Progressive-era antivaccination movement are still with us: How far should the government go to protect us from peril? What happens when the interests of public health collide with religious beliefs and personal conscience? In Pox, Willrich delivers a riveting tale about the clash of modern medicine, civil liberties, and government power at the turn of the last century that resonates powerfully today.

    After World War II, Don's work with the Air Force brought them to Colorado, where their twelve children perfectly spanned the baby boom: the oldest born in 1945, the youngest in 1965. In those years, there was an established script for a family like the Galvins—aspiration, hard work, upward mobility, domestic harmony—and they worked hard to play their parts. But behind the scenes was a different story: psychological breakdown, sudden shocking violence, hidden abuse. By the mid-1970s, six of the ten Galvin boys, one after another, were diagnosed as schizophrenic. How could all this happen to one family?What took place inside the house on Hidden Valley Road was so extraordinary that the Galvins became one of the first families to be studied by the National Institute of Mental Health. Their story offers a shadow history of the science of schizophrenia, from the era of institutionalization, lobotomy, and the schizophrenogenic mother to the search for genetic markers for the disease, always amid profound disagreements about the nature of the illness itself. And unbeknownst to the Galvins, samples of their DNA informed decades of genetic research that continues today, offering paths to treatment, prediction, and even eradication of the disease for future generations.With clarity and compassion, bestselling and award-winning author Robert Kolker uncovers one family's unforgettable legacy of suffering, love, and hope.

    In The Viral Storm, award-winning biologist Nathan Wolfe tells the story of how viruses and human beings have evolved side by side through history; how deadly viruses like HIV, swine flu, and bird flu almost wiped us out in the past; and why modern life has made our species vulnerable to the threat of a global pandemic.Wolfe's research missions to the jungles of Africa and the rain forests of Borneo have earned him the nickname "the Indiana Jones of virus hunters," and here Wolfe takes readers along on his groundbreaking and often dangerous research trips—to reveal the surprising origins of the most deadly diseases and to explain the role that viruses have played in human evolution.In a world where each new outbreak seems worse than the one before, Wolfe points the way forward, as new technologies are brought to bear in the most remote areas of the world to neutralize these viruses and even harness their power for the good of humanity. His provocative vision of the future will change the way we think about viruses, and perhaps remove a potential threat to humanity's survival.

    An ancient curse. A stunning medical mystery. And a pioneering journey into the unknown heart of the world's densest jungle.Since the days of conquistador Hernán Cortés, rumors have circulated about a lost city of immense wealth hidden somewhere in the Honduran interior, called the White City or the Lost City of the Monkey God. Indigenous tribes speak of ancestors who fled there to escape the Spanish invaders, and they warn that anyone who enters this sacred city will fall ill and die. In 1940, swashbuckling journalist Theodore Morde returned from the rainforest with hundreds of artifacts and an electrifying story of having found the Lost City of the Monkey God-but then committed suicide without revealing its location.Three quarters of a century later, author Doug Preston joined a team of scientists on a groundbreaking new quest. In 2012 he climbed aboard a rickety, single-engine plane carrying the machine that would change everything: lidar, a highly advanced, classified technology that could map the terrain under the densest rainforest canopy. In an unexplored valley ringed by steep mountains, that flight revealed the unmistakable image of a sprawling metropolis, tantalizing evidence of not just an undiscovered city but an enigmatic, lost civilization.Venturing into this raw, treacherous, but breathtakingly beautiful wilderness to confirm the discovery, Preston and the team battled torrential rains, quickmud, disease-carrying insects, jaguars, and deadly snakes. But it wasn't until they returned that tragedy struck: Preston and others found they had contracted in the ruins a horrifying, sometimes lethal-and incurable-disease.

     A riveting, powerful telling of the story of the grassroots movement of activists, many of them in a life-or-death struggle, who seized upon scientific research to help develop the drugs that turned HIV from a mostly fatal infection to a manageable disease. Ignored by public officials, religious leaders, and the nation at large, and confronted with shame and hatred, this small group of men and women chose to fight for their right to live by educating themselves and demanding to become full partners in the race for effective treatments. Around the globe, 16 million people are alive today thanks to their efforts. Not since the publication of Randy Shilts's classic And the Band Played On has a book measured the AIDS plague in such brutally human, intimate, and soaring terms. In dramatic fashion, we witness the founding of ACT UP and TAG (Treatment Action Group), and the rise of an underground drug market in opposition to the prohibitively expensive (and sometimes toxic) AZT. We watch as these activists learn to become their own researchers, lobbyists, drug smugglers, and clinicians, establishing their own newspapers, research journals, and laboratories, and as they go on to force reform in the nation s disease-fighting agencies. With his unparalleled access to this community David France illuminates the lives of extraordinary characters, including the closeted Wall Street trader-turned-activist, the high school dropout who found purpose battling pharmaceutical giants in New York, the South African physician who helped establish the first officially recognized buyers club at the height of the epidemic, and the public relations executive fighting to save his own life for the sake of his young daughter. Expansive yet richly detailed, this is an insider's account of a pivotal moment in the history of American civil rights. Powerful, heart-wrenching, and finally exhilarating, How to Survive a Plague is destined to become an essential part of the literature of AIDS.

    The Sackler name adorns the walls of many storied institutions: Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, known for their lavish donations to the arts and sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing OxyContin, a blockbuster painkiller that was a catalyst for the opioid crisis.Empire of Pain is a masterpiece of narrative reporting and writing, exhaustively documented and ferociously compelling.

    As seen on Netflix's The Crown.Anne Glenconner has been at the center of the royal circle from childhood, when she met and befriended the future Queen Elizabeth II and her sister, the Princess Margaret. Though the firstborn child of the 5th Earl of Leicester, who controlled one of the largest estates in England, as a daughter she was deemed "the greatest disappointment" and unable to inherit. Since then she has needed all her resilience to survive the vipers of court life with her sense of humor intact. A unique witness to landmark moments in royal history, Maid of Honor at Queen Elizabeth's coronation, and a lady in waiting to Princess Margaret until her death in 2002, Anne's life has encompassed extraordinary drama and tragedy. In Lady in Waiting, she will share many intimate royal stories from her time as Princess Margaret's closest confidante as well as her own battle for survival: her broken-off first engagement on the basis of her "mad blood"; her 54-year marriage to the volatile, unfaithful Colin Tennant, Lord Glenconner, who left his fortune to a former servant; the death in adulthood of two of her sons; a third son she nursed back from a six-month coma following a horrific motorcycle accident. Through it all, Anne has carried on, traveling the world with the royal family, including visiting the White House, and developing the Caribbean island of Mustique as a safe harbor for the rich and famous-hosting Mick Jagger, David Bowie, Raquel Welch, and many other politicians, aristocrats, and celebrities.

    Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The birth of genetics in the early 1900s seemed to do precisely that. Gradually, people translated their old notions about heredity into a language of genes. As the technology for studying genes became cheaper, millions of people ordered genetic tests to link themselves to missing parents, to distant ancestors, to ethnic identities. . . .But, Zimmer writes, "Each of us carries an amalgam of fragments of DNA, stitched together from some of our many ancestors. Each piece has its own ancestry, traveling a different path back through human history. A particular fragment may sometimes be cause for worry, but most of our DNA influences who we are--our appearance, our height, our penchants--in inconceivably subtle ways." Heredity isn't just about genes that pass from parent to child. Heredity continues within our own bodies, as a single cell gives rise to trillions of cells that make up our bodies. We say we inherit genes from our ancestors--using a word that once referred to kingdoms and estates--but we inherit other things that matter as much or more to our lives, from microbes to technologies we use to make life more comfortable. We need a new definition of what heredity is and, through Carl Zimmer's lucid exposition and storytelling, this resounding tour de force delivers it. Weaving historical and current scientific research, his own experience with his two daughters, and the kind of original reporting expected of one of the world's best science journalists, Zimmer ultimately unpacks urgent bioethical quandaries arising from new biomedical technologies, but also long-standing presumptions about who we really are and what we can pass on to future generations.

    She was a mother of nine and grandmother of forty-two and the matriarch of royal Europe through her children’s marriages. To many, Queen Victoria is a ruler shrouded in myth and mystique, an aging, stiff widow paraded as the figurehead to an all-male imperial enterprise. But in truth, Britain's longest-reigning monarch was one of the most passionate, expressive, humorous and unconventional women who ever lived, and the story of her life continues to fascinate.A. N. Wilson's exhaustively researched and definitive biography includes a wealth of new material from previously unseen sources to show us Queen Victoria as she’s never been seen before. Wilson explores the curious set of circumstances that led to Victoria's coronation, her strange and isolated childhood, her passionate marriage to Prince Albert and his pivotal influence even after death and her widowhood and subsequent intimate friendship with her Highland servant John Brown, all set against the backdrop of this momentous epoch in Britain’s history — and the world’s.Born at the very moment of the expansion of British political and commercial power across the globe, Victoria went on to chart a unique course for her country even as she became the matriarch of nearly every great dynasty of Europe. Her destiny was thus interwoven with those of millions of people — not just in Europe but in the ever-expanding empire that Britain was becoming throughout the nineteenth century. The famed queen had a face that adorned postage stamps, banners, statues and busts all over the known world.Wilson's Victoria is a towering achievement, a masterpiece of biography by a writer at the height of his powers.

    Scott Fitzgerald, Thomas Wolfe, Teddy Roosevelt, John Singer Sargent, James Whistler, Henry James, and Edith Wharton.Orphaned at a young age, Edith Stuyvesant Dresser claimed lineage from one of New York’s best-known families. She grew up in Newport and Paris, and her engagement and marriage to George Vanderbilt was one of the most watched events of Gilded Age society. But none of this prepared her to be mistress of Biltmore House.Before their marriage, the wealthy and bookish Vanderbilt had dedicated his life to creating a spectacular European-style estate on 125,000 acres of North Carolina wilderness. He summoned the famous landscape architect Frederick Law Olmsted to tame the grounds, collaborated with celebrated architect Richard Morris Hunt to build a 175,000-square-foot chateau, filled it with priceless art and antiques, and erected a charming village beyond the gates. Newlywed Edith was now mistress of an estate nearly three times the size of Washington, DC and benefactress of the village and surrounding rural area. When fortunes shifted and changing times threatened her family, her home, and her community, it was up to Edith to save Biltmore—and secure the future of the region and her husband’s legacy.The Last Castle is the uniquely American story of how the largest house in America flourished, faltered, and ultimately endured to this day.