She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

    This minute-by-minute account of the only manned NASA mission to have malfunctioned outside Earth's orbit describes the entire episode.

    He’s taken sf to places it’s never been (Snow Crash, Anathem). He’s reinvented the historical novel (The Baroque Cycle), the international thriller (Reamde), and both at the same time (Cryptonomicon).Now he treats his legion of fans to Some Remarks, an enthralling collection of essays—Stephenson’s first nonfiction work since his long essay on technology, In the Beginning…Was the Command Line, more than a decade ago—as well as new and previously published short writings both fiction and non.Some Remarks is a magnificent showcase of a brilliantly inventive mind and talent, as he discourses on everything from Sir Isaac Newton to Star Wars.

    Two hours after their jump, all but three of these men were dead or mortally burned from a "blowup" -- an explosive, 2,000-degree firestorm 300 feet deep and 200 feet tall -- a deadly explosion of flame and wind rarely encountered and little understood at the time.  Only seconds ahead of the approaching firestorm, the foreman, R. Wagner Dodge, throws himself into the ashes of an "escape fire " - and survives as most of his confused men run, their last moments obscured by smoke. The parents of the dead cry murder, charging that the foreman's fire killed their boys.  Exactly what happened in Mann Gulch that day has been obscured by years of grief and controversy. Now a master storyteller finally gives the Mann Gulch fire its due as tragedy.     These first deaths among the Forest Service's elite firefighters prompted widespread examination of federal fire policy, of the field of fire science, and of the frailty of young men. For Maclean, who witnessed the fire from the ground in August of 1949,  and even then he knew he would one day become a part of its story.  It is a story of Montana, of the ways of wildfires, firefighters, and fire scientists, and especially of a crew, young and proud, who "hadn't learned to count the odds and to sense they might owe the universe a tragedy." This tale is also Maclean's own, the story of a writer obsessed by a strange and human horror, unable to let the truth die with these young men, searching for the last - and lasting - word. A canvas on which to tell many stories, including the story of his research into the story itself. And finally Nature's violence colliding with human fallibility.      Haunted by these deaths for forty years, Norman Maclean returned to the scene with two of the survivors and pursues the mysteries that Mann Gulch has kept hidden since 1949.  From the words of witnesses, the evidence of history, and the research of fire scientists, Maclean at last assembles the scattered pieces of the Mann Gulch tragedy; in his last work that consumed 14 years of his life, and earned a 1992 National Book Critics Circle Award.       The excruciating detail of this book makes for a sobering reading experience. Maclean -- a former University of Chicago English professor and avid fisherman -- also wrote A River Runs Through It and Other Stories , which is set along the Missouri River, one gulch downstream from Mann Gulch.       "A magnificent drama of writing, a tragedy that pays tribute to the dead and offers rescue to the living.... Maclean's search for the truth, which becomes an exploration of his own mortality, is more compelling even than his journey into the heart of the fire. His description of the conflagration terrifies, but it is his battle with words, his effort to turn the story of the 13 men into tragedy that makes this book a classic."          —  from New York Times Book Review Editor's Choice, Best Books of 1992 The Men who Perished in the Mann Gulch Fire: Robert J. Bennett
Eldon E. Diettert
James O. Harrison
William J. Heilman
Phillip R. McVey
David R. Navon
Leonard L. Piper
Stanley J. Reba
Marvin L. Sherman
Joseph B. Sylvia
Henry J. Thol, Jr.
Newton R. Thompson
Silas R. Thompson Survivors of the Fire: R. Wagner Dodge, foreman
Walter B. Rumsey
Robert W. Sallee

    But between conception and execution there was the vastness of space itself, to say nothing of monumental technological challenges. Homesteading Space, by two of Skylab’s own astronauts and a NASA journalist, tells the dramatic story of America’s first space station from beginning to fiery end.  Homesteading Space is much more than a story of technological and scientific success; it is also an absorbing, sometimes humorous, often inspiring account of the determined, hardworking individuals who shepherded the program through a near-disastrous launch, a heroic rescue, and an exhausting study of Comet Kohoutek, as well as the lab's ultimate descent into the Indian Ocean. Featuring the unpublished in-flight diary of astronaut Alan Bean, the book is replete with the personal recollections and experiences of the Skylab crew and those who worked with them in training, during the mission, and in bringing them safely home.

    A strong gravitational wave will briefly change that distance by less than the thickness of a human hair. We have perhaps less than a few tenths of a second to perform this measurement. And we don’t know if this infinitesimal event will come next month, next year or perhaps in thirty years.In 1916 Einstein predicted the existence of gravitational waves: miniscule ripples in the very fabric of spacetime generated by unfathomably powerful events. If such vibrations could somehow be recorded, we could observe our universe for the first time through sound: the hissing of the Big Bang, the whale-like tunes of collapsing stars, the low tones of merging galaxies, the drumbeat of two black holes collapsing into one. For decades, astrophysicists have searched for a way of doing so…In 2016 a team of hundreds of scientists at work on a billion-dollar experiment made history when they announced the first ever detection of a gravitational wave, confirming Einstein’s prediction. This is their story, and the story of the most sensitive scientific instrument ever made: LIGO.Based on complete access to LIGO and the scientists who created it, Black Hole Blues provides a firsthand account of this astonishing achievement: a compelling, intimate portrait of cutting-edge science at its most awe-inspiring and ambitious.

    From the United States Memory Championship to deep within the author's own mind, this is an electrifying work of journalism that reminds us that, in every way that matters, we are the sum of our memories.

    The Sackler name adorns the walls of many storied institutions: Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, known for their lavish donations to the arts and sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing OxyContin, a blockbuster painkiller that was a catalyst for the opioid crisis.Empire of Pain is a masterpiece of narrative reporting and writing, exhaustively documented and ferociously compelling.

    government faced many difficult decisions, including what to do with the Third Reich’s scientific minds. These were the brains behind the Nazis’ once-indomitable war machine. So began Operation Paperclip, a decades-long, covert project to bring Hitler’s scientists and their families to the United States.Many of these men were accused of war crimes, and others had stood trial at Nuremberg; one was convicted of mass murder and slavery. They were also directly responsible for major advances in rocketry, medical treatments, and the U.S. space program. Was Operation Paperclip a moral outrage, or did it help America win the Cold War?Drawing on exclusive interviews with dozens of Paperclip family members, colleagues, and interrogators, and with access to German archival documents (including previously unseen papers made available by direct descendants of the Third Reich’s ranking members), files obtained through the Freedom of Information Act, and dossiers discovered in government archives and at Harvard University, Annie Jacobsen follows more than a dozen German scientists through their postwar lives and into a startling, complex, nefarious, and jealously guarded government secret of the twentieth century.In this definitive, controversial look at one of America’s most strategic, and disturbing, government programs, Jacobsen shows just how dark government can get in the name of national security.

    From training to launch, from his historic spacewalk to re-entry, he reveals for readers of all ages the cutting-edge science behind his ground-breaking experiments, and the wonders of day-to-day life on board the International Space Station.The public were invited to submit questions using the hashtag #askanastronaut, and a selection are answered by Tim in the book, which will be accompanied with illustrations, diagrams and never-before-seen photos.Tim is pleased to announce that, as with his previous book, royalties received from the book will be donated to The Prince’s Trust.

    

    As recounted by Ben Rich, the operation's brilliant boss for nearly two decades, the chronicle of Lockheed's legendary Skunk Works is a drama of cold war confrontations and Gulf War air combat, of extraordinary feats of engineering & achievement against fantastic odds. Here are up-close portraits of the maverick band of scientists & engineers who made the Skunk Works so renowned. Filled with telling personal anecdotes & high adventure, with narratives from the CIA & from Air Force pilots who flew the many classified, risky missions, this book is a portrait of the most spectacular aviation triumphs of the 20th century.

    But soon, Earth's isolation could come to an end. Over the past two decades, astronomers have discovered thousands of planets orbiting other stars. Some of these exoplanets may be mirror images of our own world. And more are being found all the time.Yet as the pace of discovery quickens, an answer to the universe's greatest riddle still remains just out of reach: Is the great silence and emptiness of the cosmos a sign that we and our world are somehow singular, special, and profoundly alone, or does it just mean that we’re looking for life in all the wrong places? As star-gazing scientists come closer to learning the truth, their insights are proving ever more crucial to understanding life’s intricate mysteries and possibilities right here on Earth.Science journalist Lee Billings explores the past and future of the "exoplanet boom" through in-depth reporting and interviews with the astronomers andplanetary scientists at its forefront. He recounts the stories behind their world-changing discoveries and captures the pivotal moments that drove them forward in their historic search for the first habitable planets beyond our solar system. Billings brings readers close to a wide range of fascinating characters, such as:FRANK DRAKE, a pioneer who has used the world’s greatest radio telescopes to conduct the first searches for extraterrestrial intelligence and to transmit a message to the stars so powerful that it briefly outshone our Sun.JIM KASTING, a mild-mannered former NASA scientist whose research into the Earth’s atmosphere and climate reveals the deepest foundations of life on our planet, foretells the end of life on Earth in the distant future, and guides the planet hunters in their search for alien life.SARA SEAGER, a visionary and iron-willed MIT professor who dreams of escaping the solar system and building the giant space telescopes required to discover and study life-bearing planets around hundreds of the Sun’s neighboring stars.Through these and other captivating tales, Billings traces the triumphs, tragedies, and betrayals of the extraordinary men and women seeking life among the stars. In spite of insufficient funding, clashing opinions, and the failings of some of our world’s most prominent and powerful scientific organizations, these planet hunters will not rest until they find the meaning of life in the infinite depths of space. Billings emphasizes that the heroic quest for other Earth-like planets is not only a scientific pursuit, but also a reflection of our own culture’s timeless hopes and fears.

    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    But the president insisted there was nothing to worry about.Fortunately, we are still a nation of skeptics. Fortunately, there are those among us who study pandemics and are willing to look unflinchingly at worst-case scenarios. Michael Lewis’s taut and brilliant nonfiction thriller pits a band of medical visionaries against the wall of ignorance that was the official response of the Trump administration to the outbreak of COVID-19.The characters you will meet in these pages are as fascinating as they are unexpected. A thirteen-year-old girl’s science project on transmission of an airborne pathogen develops into a very grown-up model of disease control. A local public-health officer uses her worm’s-eye view to see what the CDC misses, and reveals great truths about American society. A secret team of dissenting doctors, nicknamed the Wolverines, has everything necessary to fight the pandemic: brilliant backgrounds, world-class labs, prior experience with the pandemic scares of bird flu and swine flu…everything, that is, except official permission to implement their work.Michael Lewis is not shy about calling these people heroes for their refusal to follow directives that they know to be based on misinformation and bad science. Even the internet, as crucial as it is to their exchange of ideas, poses a risk to them. They never know for sure who else might be listening in.