This was the world of medicine when Thomas Dent Mütter began his trailblazing career as a plastic surgeon in Philadelphia during the middle of the nineteenth century.Although he died at just forty-eight, Mütter was an audacious medical innovator who pioneered the use of ether as anesthesia, the sterilization of surgical tools, and a compassion-based vision for helping the severely deformed, which clashed spectacularly with the sentiments of his time.   Brilliant, outspoken, and brazenly handsome, Mütter was flamboyant in every aspect of his life. He wore pink silk suits to perform surgery, added an umlaut to his last name just because he could, and amassed an immense collection of medical oddities that would later form the basis of Philadelphia’s Mütter Museum. Cristin O’Keefe Aptowicz chronicles how Mütter’s efforts helped establish Philadelphia as a global mecca for medical innovation—despite intense resistance from his numerous rivals.

    Set amid the civil rights movement, the never-before-told true story of NASA’s African-American female mathematicians who played a crucial role in America’s space program. Before Neil Armstrong walked on the moon, a group of professionals worked as ‘Human Computers’, calculating the flight paths that would enable these historic achievements. Among these were a coterie of bright, talented African-American women. Segregated from their white counterparts, these ‘coloured computers’ used pencil and paper to write the equations that would launch rockets and astronauts, into space. Moving from World War II through NASA’s golden age, touching on the civil rights era, the Space Race, the Cold War and the women’s rights movement, ‘Hidden Figures’ interweaves a rich history of mankind’s greatest adventure with the intimate stories of five courageous women whose work forever changed the world.

    He was one of the leading pioneers of the greatest revolution in twentieth-century science: quantum mechanics. The youngest theoretician ever to win the Nobel Prize for Physics, he was also pathologically reticent, strangely literal-minded and legendarily unable to communicate or empathize. Through his greatest period of productivity, his postcards home contained only remarks about the weather.Based on a previously undiscovered archive of family papers, Graham Farmelo celebrates Dirac's massive scientific achievement while drawing a compassionate portrait of his life and work. Farmelo shows a man who, while hopelessly socially inept, could manage to love and sustain close friendship.The Strangest Man is an extraordinary and moving human story, as well as a study of one of the most exciting times in scientific history.'A wonderful book . . . Moving, sometimes comic, sometimes infinitely sad, and goes to the roots of what we mean by truth in science.' Lord Waldegrave, Daily Telegraph

    Uber had catapulted to the top of the tech world, yet for many came to symbolize everything wrong with Silicon Valley.Award-winning New York Times technology correspondent Mike Isaac’s Super Pumped presents the dramatic rise and fall of Uber, set against an era of rapid upheaval in Silicon Valley. Backed by billions in venture capital dollars and led by a brash and ambitious founder, Uber promised to revolutionize the way we move people and goods through the world. A near instant “unicorn,” Uber seemed poised to take its place next to Amazon, Apple, and Google as a technology giant.What followed would become a corporate cautionary tale about the perils of startup culture and a vivid example of how blind worship of startup founders can go wildly wrong. Isaac recounts Uber’s pitched battles with taxi unions and drivers, the company’s toxic internal culture, and the bare-knuckle tactics it devised to overcome obstacles in its quest for dominance. With billions of dollars at stake, Isaac shows how venture capitalists asserted their power and seized control of the startup as it fought its way toward its fateful IPO.Based on hundreds of interviews with current and former Uber employees, along with previously unpublished documents, Super Pumped is a page-turning story of ambition and deception, obscene wealth, and bad behavior that explores how blistering technological and financial innovation culminated in one of the most catastrophic twelve-month periods in American corporate history.

    What really happened in 1969? In 1999, when Tom O'Neill was assigned a magazine piece about the thirtieth anniversary of the Manson murders, he worried there was nothing new to say. Weren't the facts indisputable? Charles Manson had ordered his teenage followers to commit seven brutal murders, and in his thrall, they'd gladly complied. But when O'Neill began reporting the story, he kept finding holes in the prosecutor Vincent Bugliosi's narrative, long enshrined in the best-selling Helter Skelter. Before long, O'Neill had questions about everything from the motive to the manhunt. Though he'd never considered himself a conspiracy theorist, the Manson murders swallowed the next two decades of his career. He was obsessed. Searching but never speculative, CHAOS follows O'Neill's twenty-year effort to rebut the "official" story behind Manson. Who were his real friends in Hollywood, and how far would they go to hide their ties? Why didn't law enforcement act on their many chances to stop him? And how did he turn a group of peaceful hippies into remorseless killers? O'Neill's hunt for answers leads him from reclusive celebrities to seasoned spies, from the Summer of Love to the shadowy sites of the CIA's mind-control experiments, on a trail rife with cover-ups and coincidences. Featuring hundreds of new interviews and dozens of never-before-seen documents from the LAPD, the FBI, and the CIA, CHAOS mounts an argument that could be, according to Los Angeles Deputy District Attorney Stephen Kay, strong enough to overturn the verdicts on the Manson murders. In those two dark nights in Los Angeles, O'Neill finds the story of California in the sixties: when charlatans mixed with prodigies, free love was as possible as brainwashing, and utopia-or dystopia-was just an acid trip away.

    Then, in 2005, astronomer Mike Brown made the discovery of a lifetime: a tenth planet, Eris, slightly bigger than Pluto. But instead of its resulting in one more planet being added to our solar system, Brown’s find ignited a firestorm of controversy that riled the usually sedate world of astronomy and launched him into the public eye. The debate culminated in the demotion of Pluto from real planet to the newly coined category of “dwarf” planet. Suddenly Brown was receiving hate mail from schoolchildren and being bombarded by TV reporters—all because of the discovery he had spent years searching for and a lifetime dreaming about.Filled with both humor and drama, How I Killed Pluto and Why It Had It Coming is Mike Brown’s engaging first-person account of the most tumultuous year in modern astronomy—which he inadvertently caused. As it guides readers through important scientific concepts and inspires us to think more deeply about our place in the cosmos, it is also an entertaining and enlightening personal story: While Brown sought to expand our understanding of the vast nature of space, his own life was changed in the most immediate, human ways by love, birth, and death. A heartfelt and personal perspective on the demotion of everyone’s favorite farflung planet, How I Killed Pluto and Why It Had It Coming is the book for anyone, young or old, who has ever dreamed of exploring the universe—and who among us hasn’t?

    On the eve of this centenary, journalist Johann Hari set off on an epic three-year, thirty-thousand-mile journey into the war on drugs. What he found is that more and more people all over the world have begun to recognize three startling truths: Drugs are not what we think they are. Addiction is not what we think it is. And the drug war has very different motives to the ones we have seen on our TV screens for so long.In Chasing the Scream, Hari reveals his discoveries entirely through the stories of people across the world whose lives have been transformed by this war. They range from a transsexual crack dealer in Brooklyn searching for her mother, to a teenage hit-man in Mexico searching for a way out. It begins with Hari's discovery that at the birth of the drug war, Billie Holiday was stalked and killed by the man who launched this crusade--and it ends with the story of a brave doctor who has led his country to decriminalize every drug, from cannabis to crack, with remarkable results.Chasing the Scream lays bare what we really have been chasing in our century of drug war--in our hunger for drugs, and in our attempt to destroy them. This book will challenge and change how you think about one of the most controversial--and consequential--questions of our time.

    How does Jane Goodall’s relationship with her dog Rusty inform her thinking about our relationship to other species? Which time and place would Jared Diamond most prefer to live in, in light of his work on the role of chance in history? What does driving a sports car have to do with Steven Weinberg’s quest for the “theory of everything”? Physicist and journalist Stefan Klein’s intimate conversations with nineteen of the world’s best-known scientists (including three Nobel Laureates) let us listen in as they talk about their paradigm-changing work—and how it is deeply rooted in their daily lives. • Cosmologist Martin Rees on the beginning and end of the world • Evolutionary biologist Richard Dawkins on egoism and selflessness • Neuroscientist V. S. Ramachandran on consciousness • Molecular biologist Elizabeth Blackburn on aging • Philosopher Peter Singer on morality • Physician and social scientist Nicholas Christakis on human relationships • Biochemist Craig Venter on the human genome • Chemist and poet Roald Hoffmann on beauty

    Czerski provides the tools to alter the way we see everything around us by linking ordinary objects and occurrences, like popcorn popping, coffee stains, and fridge magnets, to big ideas like climate change, the energy crisis, or innovative medical testing. She provides answers to vexing questions: How do ducks keep their feet warm when walking on ice? Why does it take so long for ketchup to come out of a bottle? Why does milk, when added to tea, look like billowing storm clouds? In an engaging voice at once warm and witty, Czerski shares her stunning breadth of knowledge to lift the veil of familiarity from the ordinary.

    Much like human families, tree parents live together with their children, communicate with them, and support them as they grow, sharing nutrients with those who are sick or struggling and creating an ecosystem that mitigates the impact of extremes of heat and cold for the whole group. As a result of such interactions, trees in a family or community are protected and can live to be very old. In contrast, solitary trees, like street kids, have a tough time of it and in most cases die much earlier than those in a group.Drawing on groundbreaking new discoveries, Wohlleben presents the science behind the secret and previously unknown life of trees and their communication abilities; he describes how these discoveries have informed his own practices in the forest around him. As he says, a happy forest is a healthy forest, and he believes that eco-friendly practices not only are economically sustainable but also benefit the health of our planet and the mental and physical health of all who live on Earth.

    That day--chosen completely at random--turned out to be Sunday, December 28, 1986, by any conventional measure a most ordinary day. Weingarten spent the next six years proving that there is no such thing.That Sunday between Christmas and New Year's turned out to be filled with comedy, tragedy, implausible irony, cosmic comeuppances, kindness, cruelty, heroism, cowardice, genius, idiocy, prejudice, selflessness, coincidence, and startling moments of human connection, along with evocative foreshadowing of momentous events yet to come. Lives were lost. Lives were saved. Lives were altered in overwhelming ways. Many of these events never made it into the news; they were private dramas in the lives of private people. They were utterly compelling.One Day asks and answers the question of whether there is even such a thing as "ordinary" when we are talking about how we all lurch and stumble our way through the daily, daunting challenge of being human.

    Perhaps the world's greatest technological achievement-and a triumph of American spirit and ingenuity-the Apollo 11 mission, and the entire Apollo program, was a mammoth undertaking involving more than 410,000 men and women dedicated to putting a man on the Moon and winning the Space Race against the Soviets.Seen through the eyes of the those who lived it, Shoot for the Moon reveals the dangers, the challenges, and the sheer determination that defined not only Apollo 11, but also the Mercury and Gemini missions that made it possible. Both sweeping and intimate, and based on exhaustive research and dozens of fresh interviews, bestselling author James Donovan's Shoot for the Moon is the definitive and thrilling account of one of humankind's most extraordinary feats of exploration.

    The shamed are people like us - people who, say, made a joke on social media that came out badly, or made a mistake at work. Once their transgression is revealed, collective outrage circles with the force of a hurricane and the next thing they know they're being torn apart by an angry mob, jeered at, demonized, sometimes even fired from their job. People are using shame as a form of social control.

    airspace on September 11, the population of this small town on Newfoundland Island swelled from 10,300 to nearly 17,000. The citizens of Gander met the stranded passengers with an overwhelming display of friendship and goodwill. As the passengers stepped from the airplanes, exhausted, hungry and distraught after being held on board for nearly 24 hours while security checked all of the baggage, they were greeted with a feast prepared by the townspeople. Local bus drivers who had been on strike came off the picket lines to transport the passengers to the various shelters set up in local schools and churches. Linens and toiletries were bought and donated. A middle school provided showers, as well as access to computers, email, and televisions, allowing the passengers to stay in touch with family and follow the news.Over the course of those four days, many of the passengers developed friendships with Gander residents that they expect to last a lifetime. As a show of thanks, scholarship funds for the children of Gander have been formed and donations have been made to provide new computers for the schools. This book recounts the inspiring story of the residents of Gander, Canada, whose acts of kindness have touched the lives of thousands of people and been an example of humanity and goodwill.

    After World War II, Don's work with the Air Force brought them to Colorado, where their twelve children perfectly spanned the baby boom: the oldest born in 1945, the youngest in 1965. In those years, there was an established script for a family like the Galvins—aspiration, hard work, upward mobility, domestic harmony—and they worked hard to play their parts. But behind the scenes was a different story: psychological breakdown, sudden shocking violence, hidden abuse. By the mid-1970s, six of the ten Galvin boys, one after another, were diagnosed as schizophrenic. How could all this happen to one family?What took place inside the house on Hidden Valley Road was so extraordinary that the Galvins became one of the first families to be studied by the National Institute of Mental Health. Their story offers a shadow history of the science of schizophrenia, from the era of institutionalization, lobotomy, and the schizophrenogenic mother to the search for genetic markers for the disease, always amid profound disagreements about the nature of the illness itself. And unbeknownst to the Galvins, samples of their DNA informed decades of genetic research that continues today, offering paths to treatment, prediction, and even eradication of the disease for future generations.With clarity and compassion, bestselling and award-winning author Robert Kolker uncovers one family's unforgettable legacy of suffering, love, and hope.