But things didn't turn out that way. For a start, we turned out to have far fewer genes than originally thought - just over 20,000, the same sort of number as a fruit fly or worm. What's more, the proportionof DNA consisting of genes coding for proteins was a mere 2%. So, was the rest of the genome accumulated 'junk'?Things have changed since those early heady days of the Human Genome Project. But the emerging picture is if anything far more exciting. In this book, John Parrington explains the key features that are coming to light - some, such as the results of the international ENCODE programme, still much debated and controversial in their scope. He gives an outline of the deeper genome, involving layers of regulatory elements controlling and coordinating the switching on and off of genes; the impact ofits 3D geometry; the discovery of a variety of new RNAs playing critical roles; the epigenetic changes influenced by the environment and life experiences that can make identical twins different and be passed on to the next generation; and the clues coming out of comparisons with the genomes ofNeanderthals as well as that of chimps about the development our species. We are learning more about ourselves, and about the genetic aspects of many diseases. But in its complexity, flexibility, and ability to respond to environmental cues, the human genome is proving to be far more subtle than we ever imagined.

    Acclaimed writer Charles Schaar Murray's Boogie Man is the authorized and authoritative biography of this musician whose extraordinary career spanned over fifty years and included over one-hundred albums and five Grammy Awards. Murray was given unparalleled access to Hooker, and lets him tell his own story in his own words, from life in the Deep South to San Francisco, from the 1948 blues anthem "Boogie Chillen" to the Grammy-winning album The Healer nearly a half-century later. Boogie Man is far more than merely a brilliant biography of one man; it also gives the story of the music that inspired him. "When I die," Hooker said, they'll bury the blues with me. But the blues will never die." Here is the book that does him and his music full justice.

    Dumb crooks, celebrities gone bad, unsolved mysteries, odd laws, and more—Strange Crime has plenty of stories that will make you ask yourself, “What could they possibly have been thinking?” This easily portable paperback book is ideal for readers on the go. Take it to school, to work, to jury duty!

    Its effects on our view of life have been wide and deep. One of the most world-shaking books ever published, Charles Darwin's On the Origin of Species, first appeared in print over 130 years ago, and it touched off a debate that rages to this day.Every modern evolutionist turns to Darwin's work again and again. Current controversies in the life sciences very often have as their starting point some vagueness in Darwin's writings or some question Darwin was unable to answer owing to the insufficient biological knowledge available during his time. Despite the intense study of Darwin's life and work, however, many of us cannot explain his theories (he had several separate ones) and the evidence and reasoning behind them, nor do we appreciate the modifications of the Darwinian paradigm that have kept it viable throughout the twentieth century.Who could elucidate the subtleties of Darwin's thought and that of his contemporaries and intellectual heirs--A. R. Wallace, T. H. Huxley, August Weismann, Asa Gray--better than Ernst Mayr, a man considered by many to be the greatest evolutionist of the century? In this gem of historical scholarship, Mayr has achieved a remarkable distillation of Charles Darwin's scientific thought and his enormous legacy to twentieth-century biology. Here we have an accessible account of the revolutionary ideas that Darwin thrust upon the world. Describing his treatise as "one long argument," Darwin definitively refuted the belief in the divine creation of each individual species, establishing in its place the concept that all of life descended from a common ancestor. He proposed the idea that humans were not the special products of creation but evolved according to principles that operate everywhere else in the living world; he upset current notions of a perfectly designed, benign natural world and substituted in their place the concept of a struggle for survival; and he introduced probability, chance, and uniqueness into scientific discourse.This is an important book for students, biologists, and general readers interested in the history of ideas--especially ideas that have radically altered our worldview. Here is a book by a grand master that spells out in simple terms the historical issues and presents the controversies in a manner that makes them understandable from a modern perspective.

    To understand the universe in the far future, we must first describe its present state and structure on the grand scale, and how its present properties arose. Dr Islam explains these topics in an accessible way in the first part of the book. From this background he speculates about the future evolution of the universe and predicts the major changes that will occur. The author has largely avoided mathematical formalism and therefore the book is well suited to general readers with a modest background knowledge of physics and astronomy.

    Channelling our twin urges to explore and understand, geographers uncover the hidden connections of human existence, from infant mortality in inner cities to the decision-makers who fly overhead in executive jets, from natural disasters to over-use of fossil fuels.In this incisive introduction to the subject, Danny Dorling and Carl Lee reveal geography as a science which tackles all of the biggest issues that face us today, from globalisation to equality, from sustainability to population growth, from climate change to changing technology - and the complex interactions between them all.Illustrated by a series of award-winning maps created by Benjamin D. Hennig, this is a book for anyone who wants to know more about why our world is the way it is today, and where it might be heading next.

    Today, more than sixty years later, members of a new generation of scientists are attempting to create life from the ground up. Science has moved forward in leaps and bounds since Schrodinger's time, but our understanding of what does and does not constitute life has only grown more complex. An era that has already seen computer chip-implanted human brains, genetically engineered organisms, genetically modified foods, cloned mammals, and brain-dead humans kept alive by machines is one that demands fresh thinking about the concept of life. While a segment of our national debate remains stubbornly mired in moral quandaries over abortion, euthanasia, and other right to life issues, the science writer Ed Regis demonstrates how science can and does provide us with a detailed understanding of the nature of life. Written in a lively and accessible style, and synthesizing a wide range of contemporary research, What Is Life? is a brief and illuminating contribution to an age-old debate.

    But most of us know very little about how the disease works, why we treat it the way we do, and the personalities whose dedication got us where we are today. For fifty years, Dr. Vincent T. DeVita Jr. has been one of those key players: he has held just about every major position in the field, and he developed the first successful chemotherapy treatment for Hodgkin’s lymphoma, a breakthrough the American Society of Clinical Oncologists has called the top research advance in half a century of chemotherapy. As one of oncology’s leading figures, DeVita knows what cancer looks like from the lab bench and the bedside. The Death of Cancer is his illuminating and deeply personal look at the science and the history of one of the world’s most formidable diseases. In DeVita’s hands, even the most complex medical concepts are comprehensible.Cowritten with DeVita’s daughter, the science writer Elizabeth DeVita-Raeburn, The Death of Cancer is also a personal tale about the false starts and major breakthroughs, the strong-willed oncologists who clashed with conservative administrators (and one another), and the courageous patients whose willingness to test cutting-edge research helped those oncologists find potential treatments. An emotionally compelling and informative read, The Death of Cancer is also a call to arms. DeVita believes that we’re well on our way to curing cancer but that there are things we need to change in order to get there. Mortality rates are declining, but America’s cancer patients are still being shortchanged—by timid doctors, by misguided national agendas, by compromised bureaucracies, and by a lack of access to information about the strengths and weaknesses of the nation’s cancer centers.With historical depth and authenticity, DeVita reveals the true story of the fight against cancer. The Death of Cancer is an ambitious, vital book about a life-and-death subject that touches us all.

    Drawing upon new research into cat genetics, brain chemistry, evolution, social behavior, and interaction with humans and fellow felines, acclaimed author and scientist Stephen Budiansky explores the mysteries of these amazing creatures. Wide-ranging, lively, and engaging, The Character of Cats also covers the full spectrum of feline fact and lore, from history, superstition, and religious imagery to hunting patterns, sexual behavior, and preferred colors. This smart, wonderfully readable book finally gives cats their due.

    A team of fossil hunters... A desperate fight to survive.... In book 5, Hannah and the other survivors arrive in the ice world of the Pleistocene, bare of trees and with almost no animal life. Starving, with no other game to hunt, they must take on the mighty Mammoth and his wicked tusks. Can they survive the freeze long enough to jump back to modern times?

    It is rich in narrative, anecdote, attention to human detail, and stories of competition among scientists who have dominated the field.

    

    Cave paintings of the giant beasts hint at the profound role they played in early human culture-our Ice Age ancestors built igloo-shaped huts out of mammoth bones and even feasted on mammoth tongues. Eager to uncover more clues to this mystical prehistoric age, explorers since the time of Peter the Great have scoured Siberia for mammoth remains. Now a new generation of explorers has taken to the tundra. Armed with GPS, ground-penetrating radar, and Soviet-era military helicopters, they seek an elusive prize: a mammoth carcass that will help determine how the creature lived, how it died-and how it might be brought back to life.In this adventure-filled narrative, science writer Richard Stone follows two teams of explorers-one Russian/Japanese, the other a French-led consortium-as they battle bitter cold, high winds, supply shortages, and the deeply rooted superstitions of indigenous peoples who fear the consequences of awakening the "rat beneath the ice." Stone travels from St. Petersburg to the Arctic Circle, from the North Sea to high-tech Japanese laboratories, as he traces the sometimes-surreal quest of these intrepid scientists, whose work could well rewrite our planet's evolutionary history. A riveting tale of high-stakes adventure and scientific hubris, Mammoth is also an intellectual voyage through uncharted moral terrain, as we confront the promise and peril of resurrecting creatures from the deep past.

    Back in the 1990s--working undercover with his colleagues in the environmental movement--he would descend on trial sites of genetically modified crops at night and hack them to pieces. Two decades later, most people around the world--from New York to China--still think that 'GMO' foods are bad for their health or likely to damage the environment. But Mark has changed his mind. This book explains why.In 2013, in a world-famous recantation speech, Mark apologised for having destroyed GM crops. He spent the subsequent years touring Africa and Asia, and working with plant scientists who are using this technology to help smallholder farmers in developing countries cope better with pests, diseases and droughts.This book lifts the lid on the anti-GMO craze and shows how science was left by the wayside as a wave of public hysteria swept the world. Mark takes us back to the origins of the technology and introduces the scientific pioneers who invented it. He explains what led him to question his earlier assumptions about GM food, and talks to both sides of this fractious debate to see what still motivates worldwide opposition today. In the process he asks--and answers--the killer question: how did we all get it so wrong on GMOs?

    You will be astonished to learn about some of the events that have occurred! Here is a Sneak Peek of What you will Learn: - Ancient History - Asian History - European and Russian History - American History - Australian History - World Wars I & II, and the Vietnam War - And much, much, more Here is what other readers say about this book: "This book is packed with really important information about the world's history." "I was surprised how much I learned from this. I really like how everything is laid out, it makes it very easy to follow. I especially like the section on Native Americans" "I couldn't put this book down, and not because I'm a nerdy avid reader (I am) but because it's filled with so much about our world history without the facts jumping all over the place like some history books I've read." "I am highly impressed by the content of this book and I would recommend this to all my colleagues as well" Subjects include: Ancient Greece, Ancient Egypt, The Roman Empire, Constantine and Christianity, India, Ancient Korea, Chinese Dynasties, Napoleonic Europe, Foundation of USA, The 1812 War, Australia and Wars, World War I, World War II, The Ottoman Empire, Greece and North Africa, The Diem Regime, Pearl Harbor and much more! All Continents As Known Today Are Covered: North America, Europe, Asia, Africa and Australia. Take action and get this book now!