Your head hurts. You're mildly annoyed as you get the kids ready for school and dress for work yourself. Meanwhile, an epic war is being fought, just below your skin. Millions are fighting and dying for you to be able to complain as you head out the door.So what, exactly, is your immune system?Second only to the human brain in its complexity, it is one of the oldest and most critical facets of life on Earth. Without it, you would die within days. In Immune, Philipp Dettmer, the brains behind the most popular science channel on YouTube, takes readers on a journey through the fortress of the human body and its defenses. There is a constant battle of staggering scale raging within us, full of stories of invasion, strategy, defeat, and noble self-sacrifice. In fact, in the time you've been reading this, your immune system has probably identified and eradicated a cancer cell that started to grow in your body.Each chapter delves into an element of the immune system, including defenses like antibodies and inflammation as well as threats like bacteria, allergies, and cancer, as Dettmer reveals why boosting your immune system is actually nonsense, how parasites sneak their way past your body's defenses, how viruses work, and what goes on in your wounds when you cut yourself.Enlivened by engaging graphics and immersive descriptions, Immune turns one of the most intricate, interconnected, and confusing subjects—immunology—into a gripping adventure through an astonishing alien landscape. Immune is a vital and remarkably fun crash course in what is arguably, and increasingly, the most important system in the body.

    Inspired by their award-winning podcast, this popular (hopefully) science (definitely) book dedicates each chapter to a different sci-fi classic, and wittily explores the fascinating issues that arise. Covering movies from 28 Days Later to Ex Machina, this is a joyous ride through astrophysics, neuroscience, psychology, botany, artificial intelligence, evolution, and plenty more subjects you've always wanted to grasp. Now's your chance: stylishly designed and illustrated throughout, Science(ish) is the perfect gift for every curious mind.

    "A stunning memoir from the astronaut who spent a record-breaking year aboard the International Space Station – a candid account of his remarkable voyage, the journeys that preceded it, and his colorful formative years." Inside book cover comments.

    Each blockbuster has a secret history--of power, influence, dark broadcasters, and passionate cults that turn some new products into cultural phenomena. Even the most brilliant ideas wither in obscurity if they fail to connect with the right network, and the consumers that matter most aren't the early adopters, but rather their friends, followers, and imitators -- the audience of your audience.In his groundbreaking investigation, Atlantic senior editor Derek Thompson uncovers the hidden psychology of why we like what we like and reveals the economics of cultural markets that invisibly shape our lives. Shattering the sentimental myths of hit-making that dominate pop culture and business, Thompson shows quality is insufficient for success, nobody has "good taste," and some of the most popular products in history were one bad break away from utter failure. It may be a new world, but there are some enduring truths to what audiences and consumers want. People love a familiar surprise: a product that is bold, yet sneakily recognizable.Every business, every artist, every person looking to promote themselves and their work wants to know what makes some works so successful while others disappear. Hit Makers is a magical mystery tour through the last century of pop culture blockbusters and the most valuable currency of the twenty-first century--people's attention.From the dawn of impressionist art to the future of Facebook, from small Etsy designers to the origin of Star Wars, Derek Thompson leaves no pet rock unturned to tell the fascinating story of how culture happens and why things become popular.In Hit Makers, Derek Thompson investigates: - The secret link between ESPN's sticky programming and the The Weeknd's catchy choruses - Why Facebook is the world's most important modern newspaper - How advertising critics predicted Donald Trump - The 5th grader who accidentally launched "Rock Around the Clock," the biggest hit in rock and roll history - How Barack Obama and his speechwriters think of themselves as songwriters - How Disney conquered the world--but the future of hits belongs to savvy amateurs and individuals - The French collector who accidentally created the Impressionist canon - Quantitative evidence that the biggest music hits aren't always the best - Why almost all Hollywood blockbusters are sequels, reboots, and adaptations - Why one year--1991--is responsible for the way pop music sounds today - Why another year --1932--created the business model of film - How data scientists proved that "going viral" is a myth - How 19th century immigration patterns explain the most heard song in the Western Hemisphere

    We take for granted that we can remember, feel emotion, navigate, empathize, and understand the world around us, but how would our lives change if these abilities were dramatically enhanced--or disappeared overnight?Helen Thomson has spent years traveling the world, tracking down incredibly rare brain disorders. In Unthinkable she tells the stories of nine extraordinary people she encountered along the way. From the man who thinks he's a tiger to the doctor who feels the pain of others just by looking at them to a woman who hears music that’s not there, their experiences illustrate how the brain can shape our lives in unexpected and, in some cases, brilliant and alarming ways.Story by remarkable story, Unthinkable takes us on an unforgettable journey through the human brain. Discover how to forge memories that never disappear, how to grow an alien limb, and how to make better decisions. Learn how to hallucinate and how to make yourself happier in a split second. Find out how to avoid getting lost, how to see more of your reality, even how exactly you can confirm you are alive. Think the unthinkable.

    We live in an interesting time. Materially, everything is the best it’s ever been—we are freer, healthier and wealthier than any people in human history. Yet, somehow everything seems to be irreparably and horribly f*cked—the planet is warming, governments are failing, economies are collapsing, and everyone is perpetually offended on Twitter. At this moment in history, when we have access to technology, education and communication our ancestors couldn’t even dream of, so many of us come back to an overriding feeling of hopelessness.What’s going on? If anyone can put a name to our current malaise and help fix it, it’s Mark Manson. In 2016, Manson published The Subtle Art of Not Giving A F*ck, a book that brilliantly gave shape to the ever-present, low-level hum of anxiety that permeates modern living. He showed us that technology had made it too easy to care about the wrong things, that our culture had convinced us that the world owed us something when it didn’t—and worst of all, that our modern and maddening urge to always find happiness only served to make us unhappier. Instead, the “subtle art” of that title turned out to be a bold challenge: to choose your struggle; to narrow and focus and find the pain you want to sustain. The result was a book that became an international phenomenon, selling millions of copies worldwide while becoming the #1 bestseller in 13 different countries.Now, in Everthing Is F*cked, Manson turns his gaze from the inevitable flaws within each individual self to the endless calamities taking place in the world around us. Drawing from the pool of psychological research on these topics, as well as the timeless wisdom of philosophers such as Plato, Nietzsche, and Tom Waits, he dissects religion and politics and the uncomfortable ways they have come to resemble one another. He looks at our relationships with money, entertainment and the internet, and how too much of a good thing can psychologically eat us alive. He openly defies our definitions of faith, happiness, freedom—and even of hope itself.With his usual mix of erudition and where-the-f*ck-did-that-come-from humor, Manson takes us by the collar and challenges us to be more honest with ourselves and connected with the world in ways we probably haven’t considered before. It’s another counterintuitive romp through the pain in our hearts and the stress of our soul. One of the great modern writers has produced another book that will set the agenda for years to come.

    Increasingly, the decisions that affect our lives--where we go to school, whether we can get a job or a loan, how much we pay for health insurance--are being made not by humans, but by machines. In theory, this should lead to greater fairness: Everyone is judged according to the same rules.But as mathematician and data scientist Cathy O'Neil reveals, the mathematical models being used today are unregulated and uncontestable, even when they're wrong. Most troubling, they reinforce discrimination--propping up the lucky, punishing the downtrodden, and undermining our democracy in the process.

    From the moment Claire Randall stepped through a standing stone circle and was thrown back in time to the year 1743—and into a world that threatens life, limb, loyalty, heart, soul, and everything else Claire has—readers have been hungry to know everything about this world and its inhabitants, particularly a Scottish soldier named Jamie Fraser.  In this beautifully illustrated compendium of all things Outlandish, Gabaldon covers the first four novels of the main series, including:   • full synopses of Outlander, Dragonfly in Amber, Voyager, and Drums of Autumn • a complete listing of the characters (fictional and historical) in the first four novels in the series, as well as family trees and genealogical notes • a comprehensive glossary and pronunciation guide to Gaelic terms and usage • the fully explicated Gabaldon Theory of Time Travel • frequently asked questions to the author and her (sometimes surprising) answers • an annotated bibliography • essays about medicine and magic in the eighteenth century, researching historical fiction, creating characters, and more • professionally cast horoscopes for Jamie and Claire   For anyone who wants to spend more time with the Outlander characters and the world they inhabit, Diana Gabaldon here opens a door through the standing stones and offers a guided tour of what lies within.

    The human brain has some capabilities that the brains of other animals lack. It is to these distinctive capabilities that our species owes its dominant position. If machine brains surpassed human brains in general intelligence, then this new superintelligence could become extremely powerful--possibly beyond our control. As the fate of the gorillas now depends more on humans than on the species itself, so would the fate of humankind depend on the actions of the machine superintelligence.But we have one advantage: we get to make the first move. Will it be possible to construct a seed Artificial Intelligence, to engineer initial conditions so as to make an intelligence explosion survivable? How could one achieve a controlled detonation?

    Many of our wisest policy-makers, activists, scientists, and philosophers agree that the only problem with empathy is that we don’t have enough of it.Nothing could be farther from the truth, argues Yale researcher Paul Bloom. In AGAINST EMPATHY, Bloom reveals empathy to be one of the leading motivators of inequality and immorality in society. Far from helping us to improve the lives of others, empathy is a capricious and irrational emotion that appeals to our narrow prejudices. It muddles our judgment and, ironically, often leads to cruelty. We are at our best when we are smart enough not to rely on it, but to draw instead upon a more distanced compassion.Basing his argument on groundbreaking scientific findings, Bloom makes the case that some of the worst decisions made by individuals and nations—who to give money to, when to go to war, how to respond to climate change, and who to imprison—are too often motivated by honest, yet misplaced, emotions. With precision and wit, he demonstrates how empathy distorts our judgment in every aspect of our lives, from philanthropy and charity to the justice system; from medical care and education to parenting and marriage. Without empathy, Bloom insists, our decisions would be clearer, fairer, and—yes—ultimately more moral.Brilliantly argued, urgent and humane, AGAINST EMPATHY shows us that, when it comes to both major policy decisions and the choices we make in our everyday lives, limiting our impulse toward empathy is often the most compassionate choice we can make.

    Covering such turning points as the little-known Celtic and Welsh influences on English, the impact of the Viking raids and the Norman Conquest, and the Germanic invasions that started it all during the fifth century ad, John McWhorter narrates this colorful evolution with vigor. Drawing on revolutionary genetic and linguistic research as well as a cache of remarkable trivia about the origins of English words and syntax patterns, Our Magnificent Bastard Tongue ultimately demonstrates the arbitrary, maddening nature of English--and its ironic simplicity due to its role as a streamlined lingua franca during the early formation of Britain. This is the book that language aficionados worldwide have been waiting for (and no, it's not a sin to end a sentence with a preposition).

    “A marvelously readable and level-headed explanation of basic science and how it relates to the issues.” —John Tierney, New York TimesThis is “must-have” information for all presidents—and citizens—of the twenty-first century: Is Iran’s nascent nuclear capability a genuine threat to the West? Are biochemical weapons likely to be developed by terrorists? Are there viable alternatives to fossil fuels that should be nurtured and supported by the government? Should nuclear power be encouraged? Can global warming be stopped?

    xn + yn = zn, where n represents 3, 4, 5, ...no solution"I have discovered a truly marvelous demonstration of this proposition which this margin is too narrow to contain."With these words, the seventeenth-century French mathematician Pierre de Fermat threw down the gauntlet to future generations.  What came to be known as Fermat's Last Theorem looked simple; proving it, however, became the Holy Grail of mathematics, baffling its finest minds for more than 350 years.  In Fermat's Enigma--based on the author's award-winning documentary film, which aired on PBS's "Nova"--Simon Singh tells the astonishingly entertaining story of the pursuit of that grail, and the lives that were devoted to, sacrificed for, and saved by it.  Here is a mesmerizing tale of heartbreak and mastery that will forever change your feelings about mathematics.

    Richard Gott leads time travel out of the world of H. G. Wells and into the realm of scientific possibility. Building on theories posited by Einstein and advanced by scientists such as Stephen Hawking and Kip Thorne, Gott explains how time travel can actually occur. He describes, with boundless enthusiasm and humor, how travel to the future is not only possible but has already happened, and he contemplates whether travel to the past is also conceivable. Notable not only for its extraordinary subject matter and scientific brilliance, Time Travel in Einstein’s Universe is a delightful and captivating exploration of the surprising facts behind the science fiction of time travel.

    In The Master Algorithm, Pedro Domingos lifts the veil to give us a peek inside the learning machines that power Google, Amazon, and your smartphone. He assembles a blueprint for the future universal learner--the Master Algorithm--and discusses what it will mean for business, science, and society. If data-ism is today's philosophy, this book is its bible.