Increasingly fascinated by this most shameful of experiences, she began to explore the lonely city by way of art. Moving fluidly between works and lives -- from Edward Hopper's Nighthawks to Andy Warhol's Time Capsules, from Henry Darger's hoarding to the depredations of the AIDS crisis -- Laing conducts an electric, dazzling investigation into what it means to be alone, illuminating not only the causes of loneliness but also how it might be resisted and redeemed.

    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    She witnesses nurses drawing straws to see who would tend to the patient inside, all of them reluctant to enter the room. Out of impulse, Ruth herself enters the quarantined space and immediately begins to care for the young man who cries for his mother in the last moments of his life. Before she can even process what she's done, word spreads in the community that Ruth is the only person willing to help these young men afflicted by AIDS, and is called upon to nurse them. As she forges deep friendships with the men she helps, she works tirelessly to find them housing and jobs, even searching for funeral homes willing to take their bodies - often in the middle of the night. She cooks meals for tens of people out of discarded food found in the dumpsters behind supermarkets, stores rare medications for her most urgent patients, teaches sex-ed to drag queens after hours at secret bars, and becomes a beacon of hope to an otherwise spurned group of ailing gay men on the fringes of a deeply conservative state.Throughout the years, Ruth defies local pastors and nurses to help the men she cares for: Paul and Billy, Angel, Chip, Todd and Luke. Emboldened by the weight of their collective pain, she fervently advocates for their safety and visibility, ultimately advising Governor Bill Clinton on the national HIV-AIDS crisis.This deeply moving and elegiac memoir honors the extraordinary life of Ruth Coker Burks and the beloved men who fought valiantly for their lives with AIDS during a most hostile and misinformed time in America.

    In this funny, devastating, haunting memoir and with a raw and often painful honesty, she looks back at life with a painter mother, seven times married, whose outlaw spirit could tip over into psychosis, and a hard-drinking, fist-swinging father who liked nothing better than to spin tales with his cronies at the Liars' Club.

    At church and at home, Alex was taught that God had a plan for everyone. But something was gnawing at her that made her feel different. These feelings exploded when she met Yvette, a girl who made Alex feel alive in a new way, and with whom Alex would quickly fall in love.Alex knew she was holding a secret that could shatter her family, her church community, and her life. Yet when this secret couldn’t be hidden any longer, she told her parents that she was gay, and the nightmare began. She was driven from her home in Southern California to Utah, where, against her will, her parents handed her over to fellow Mormons who promised to save Alex from her homosexuality.For eight harrowing months, Alex was held captive in an unlicensed “residential treatment program” modeled on the many “therapeutic” boot camps scattered across Utah. Alex was physically and verbally abused, and many days she was forced to stand facing a wall wearing a heavy backpack full of rocks. Her captors used faith to punish and terrorize her. With the help of a dedicated legal team in Salt Lake City, Alex eventually escaped and made legal history in Utah by winning the right to live under the law’s protection as an openly gay teenager.Alex is not alone; the headlines continue to splash stories about gay conversion therapy and rehabilitation centers that promise to “save” teenagers from their sexuality. Saving Alex is a courageous memoir that tells Alex’s story in the hopes that it will bring awareness and justice to this important issue. A bold, inspiring story of one girl’s fight for freedom, acceptance, and truth.

    Operations on the brain carry grave risks. Every day, leading neurosurgeon Henry Marsh must make agonizing decisions, often in the face of great urgency and uncertainty.If you believe that brain surgery is a precise and exquisite craft, practiced by calm and detached doctors, this gripping, brutally honest account will make you think again. With astonishing compassion and candor, Marsh reveals the fierce joy of operating, the profoundly moving triumphs, the harrowing disasters, the haunting regrets, and the moments of black humor that characterize a brain surgeon's life.Do No Harm provides unforgettable insight into the countless human dramas that take place in a busy modern hospital. Above all, it is a lesson in the need for hope when faced with life's most difficult decisions.

    One day he was a doctor treating the dying, and the next he was a patient struggling to live. And just like that, the future he and his wife had imagined evaporated. When Breath Becomes Air chronicles Kalanithi's transformation from a naïve medical student "possessed," as he wrote, "by the question of what, given that all organisms die, makes a virtuous and meaningful life" into a neurosurgeon at Stanford working in the brain, the most critical place for human identity, and finally into a patient and new father confronting his own mortality. What makes life worth living in the face of death? What do you do when the future, no longer a ladder toward your goals in life, flattens out into a perpetual present? What does it mean to have a child, to nurture a new life as another fades away? These are some of the questions Kalanithi wrestles with in this profoundly moving, exquisitely observed memoir. Paul Kalanithi died in March 2015, while working on this book, yet his words live on as a guide and a gift to us all. "I began to realize that coming face to face with my own mortality, in a sense, had changed nothing and everything," he wrote. "Seven words from Samuel Beckett began to repeat in my head: 'I can't go on. I'll go on.'" When Breath Becomes Air is an unforgettable, life-affirming reflection on the challenge of facing death and on the relationship between doctor and patient, from a brilliant writer who became both.

    Though imperfect in every way, her dysfunctional childhood was as beautiful as it was strange, and as nurturing as it was difficult. At the age of five, Brandi contracted bacterial meningitis, which almost took her life, leaving an indelible mark on her formative years and altering her journey into young adulthood.As an openly gay teenager, Brandi grappled with the tension between her sexuality and her faith when her pastor publicly refused to baptize her on the day of the ceremony. Shockingly, her small town rallied around Brandi in support and set her on a path to salvation where the rest of the misfits and rejects find it: through twisted, joyful, weird, and wonderful music.In Broken Horses, Brandi Carlile takes listeners through the events of her life that shaped her very raw art - from her start at a local singing competition where she performed Elton John’s “Honky Cat” in a bedazzled white polyester suit, to her first break opening for Dave Matthews Band, to many sleepless tours over 15 years and six studio albums, all while raising two children with her wife, Catherine Shepherd. This hard-won success led her to collaborations with personal heroes like Elton John, Dolly Parton, Mavis Staples, Pearl Jam, Tanya Tucker, and Joni Mitchell, as well as her peers in the supergroup The Highwomen, and ultimately to the Grammy stage, where she converted millions of viewers into instant fans.Evocative and piercingly honest, Broken Horses is at once an examination of faith through the eyes of a person rejected by the church’s basic tenets and a meditation on the moments and lyrics that have shaped the life of a creative mind, a brilliant artist, and a genuine empath on a mission to give back.

    No money. No passport. No identity.Taken to a mental hospital by the police, MacLean then started to hallucinate so severely he had to be tied down. Soon he could remember song lyrics, but not his family, his friends, or the woman he was told he loved. All of these symptoms, it turned out, were the result of the commonly prescribed malarial medication he had been taking. Upon his return to the States, he struggled to piece together the fragments of his former life in a harrowing, absurd, and unforgettable journey back to himself.The Answer to the Riddle Is Me, drawn from David MacLean’s award-winning This American Life essay, is a deeply felt, closely researched, and intensely personal book. It asks every reader to confront the essential questions of our age: In our geographically and chemically fluid world, what makes me who I am? And how much can be stripped away before I become someone else entirely?

    Now, in Two or Three Things I Know for Sure, she takes a probing look at her family's history to give us a lyrical, complex memoir that explores how the gossip of one generation can become legends for the next.Illustrated with photographs from the author's personal collection, Two or Three Things I Know for Sure tells the story of the Gibson women -- sisters, cousins, daughters, and aunts -- and the men who loved them, often abused them, and, nonetheless, shared their destinies. With luminous clarity, Allison explores how desire surprises and what power feels like to a young girl as she confronts abuse. As always, Dorothy Allison is provocative, confrontational, and brutally honest. Two or Three Things I Know for Sure, steeped in the hard-won wisdom of experience, expresses the strength of her unique vision with beauty and eloquence.

    She was ambitious and worked hard; she had just bought an apartment; she was falling in love. But then she started to develop worrying symptoms: her face felt like it was burning whenever she was in front of the computer. Soon this progressed to an intolerance of fluorescent light, then of sunlight itself. The reaction soon spread to her entire body. Now, when her symptoms are at their worst, she must spend months on end in a blacked-out room, losing herself in audio books and elaborate word games in an attempt to ward off despair. It was during this period she began to write this book.

    By night, I am Glamrou, an empowered, fearless and acerbic drag queen who wears seven-inch heels and says the things that nobody else dares to. Growing up in a strict Iraqi Muslim household, it didn’t take long for me to realise I was different. When I was ten years old, I announced to my family that I was in love with Macaulay Culkin in Home Alone. The resultant fallout might best be described as something like the Iraqi version of Jerry Springer: The Opera. And that was just the beginning. This is the story of how I got from there to here: about my teenage obsession with marine biology, and how fluid aquatic life helped me understand my non-binary gender identity; about my two-year scholarship at Eton college, during which I wondered if I could forge a new identity as a British aristocrat (spoiler alert: it didn’t work); about discovering the transformative powers of drag while at university (and how I very nearly lost my mind after I left); and about how, after years of rage towards it, I finally began to understand Islam in a new, queer way. Most of all, this is a book about my mother. It’s the journey of how we lost and found each other, about forgiveness, understanding, hope – and the life-long search for belonging.

    By 1988 she was living at home but was brain dead after a tragic cycle of misunderstanding, over-medication, and culture clash: "What the doctors viewed as clinical efficiency the Hmong viewed as frosty arrogance." The Spirit Catches You and You Fall Down is a tragedy of Shakespearean dimensions, written with the deepest of human feeling. Sherwin Nuland said of the account, "There are no villains in Fadiman's tale, just as there are no heroes. People are presented as she saw them, in their humility and their frailty—and their nobility.

    And that's what Furiously Happy is all about."Jenny’s readings are standing room only, with fans lining up to have Jenny sign their bottles of Xanax or Prozac as often as they are to have her sign their books. Furiously Happy appeals to Jenny's core fan base but also transcends it. There are so many people out there struggling with depression and mental illness, either themselves or someone in their family—and in Furiously Happy they will find a member of their tribe offering up an uplifting message (via a taxidermied roadkill raccoon). Let's Pretend This Never Happened ostensibly was about embracing your own weirdness, but deep down it was about family. Furiously Happy is about depression and mental illness, but deep down it's about joy—and who doesn't want a bit more of that?

    Eye-opening and utterly gripping, Koren Zailckas’s story is that of thousands of girls like her who are not alcoholics yet but who routinely use booze as a shortcut to courage and a stand-in for good judgment.With one stiff sip of Southern Comfort at the age of fourteen, Zailckas is initiated into the world of drinking. From then on, she will drink faithfully, fanatically. In high school, her experimentation will lead to a stomach pumping. In college, her excess will give way to a pattern of self-poisoning that will grow more destructive each year. At age twenty-two, Zailckas will wake up in an unfamiliar apartment in New York City, elbow her friend who is passed out next to her, and ask, "Where are we?" Smashed is a sober look at how she got there and, after years of blackouts and smashups, what it took for her to realize she had to stop drinking. Smashed is an astonishing literary debut destined to become a classic.