In The Poisoner's Handbook Blum draws from highly original research to track the fascinating, perilous days when a pair of forensic scientists began their trailblazing chemical detective work, fighting to end an era when untraceable poisons offered an easy path to the perfect crime. Drama unfolds case by case as the heroes of The Poisoner's Handbook—chief medical examiner Charles Norris and toxicologist Alexander Gettler—investigate a family mysteriously stricken bald, Barnum and Bailey's Famous Blue Man, factory workers with crumbling bones, a diner serving poisoned pies, and many others. Each case presents a deadly new puzzle and Norris and Gettler work with a creativity that rivals that of the most imaginative murderer, creating revolutionary experiments to tease out even the wiliest compounds from human tissue. Yet in the tricky game of toxins, even science can't always be trusted, as proven when one of Gettler's experiments erroneously sets free a suburban housewife later nicknamed "America's Lucretia Borgia" to continue her nefarious work. From the vantage of Norris and Gettler's laboratory in the infamous Bellevue Hospital it becomes clear that killers aren't the only toxic threat to New Yorkers. Modern life has created a kind of poison playground, and danger lurks around every corner. Automobiles choke the city streets with carbon monoxide; potent compounds, such as morphine, can be found on store shelves in products ranging from pesticides to cosmetics. Prohibition incites a chemist's war between bootleggers and government chemists while in Gotham's crowded speakeasies each round of cocktails becomes a game of Russian roulette. Norris and Gettler triumph over seemingly unbeatable odds to become the pioneers of forensic chemistry and the gatekeepers of justice during a remarkably deadly time. A beguiling concoction that is equal parts true crime, twentieth-century history, and science thriller, The Poisoner's Handbook is a page-turning account of a forgotten New York.

    And in this bold 24-lecture series, you can do just that.

    A hiker brutally murdered, then thrown off a cliff in a remote mountain range. A devious killer who hid his wife's body under a thick cement patio. For investigators, the story is often the same: they know a murder took place, they may even know who did it. But without key evidence, pursuing a conviction is nearly impossible. That's when they call NecroSearch International. Necrosearch boasts a brain trust of the nation's top scientists, specialists, and behaviourists who use the latest technology and techniques to help solve "unsolvable" crimes, no matter how decayed the corpse, no matter how cleverly the killer has hidden the victim's body. Now, for the first time ever, readers are taken on a fascinating, often-shocking journey into a realm of crime investigation of which few people are aware. Necrosearch's most challenging cases are described, step-by-step, as these modern-day Sherlock Holmes's detect bodies and evidence thought irretrievable, and testify in court to bring cold-blooded killers to justice.

    Yet, as the 1700s began, the mysteries of the universe were pondered by "natural philosophers"—the term "scientist" didn't even exist until the mid 19th century—whose explanations couldn't help but be influenced by the religious thought and political and social contexts that shaped their world.The radical ideas of the Enlightenment were especially important and influential. In this course you see how the work of these natural philosophers prepared the way for the more familiar world of science we recognize today.

    But is old age all doom and gloom?Not at all! While it's true that some functions in the aging brain decline, neuroscientists have discovered that many other brain functions remain stable - or even improve - as we age. Furthermore, nurture plays as significant a role as nature, and there are a number of strategies you can implement to stave off declining brain function, including:Incorporating physical activity into your routineEating a healthy dietMaintaining a vibrant social lifeReducing your stressThe science behind the aging brain tells a fascinating - and often counterintuitive - story. Is "aging" a disease or merely a natural occurrence that produces disease-like symptoms? If humans are biologically programmed to survive and thrive, why do we age at all? Is it possible (or even desirable) to "cure" aging altogether?Delve into these questions and more in The Aging Brain. Taught by a neuroscientist and award-winning professor at the University of Michigan, these 12 eye-opening lectures will give you a wealth of new insights into what happens to the brain over time - as well as strategies to mitigate the effects of aging and enhance your quality of life into old age.With a mix of scientific research and practical applications, Professor Polk brings cutting-edge science to life. He takes you down to the cellular and even molecular levels of the brain to show you why certain functions decline, how some aspects of brain aging are under genetic control, and what you can do to prolong your health and keep your mind sharp. Aging affects us all, but you have some control over how it affects you.

    In this course, The Great Courses partners with the Smithsonian - one of the world's most storied and exceptional educational institutions - to examine the extraordinary events of this period and uncover the far-reaching impact of this incredible revolution. Over the course of 36 thought-provoking lectures, longtime Great Courses favorite Professor Allitt introduces you to the inventors, businessmen, and workers responsible for transforming virtually every aspect of our lives and fueling one of the greatest periods of innovation in human history. The technological achievements of this era are nothing short of astonishing. Thanks to inventions such as the steam engine and processes such as large-scale iron smelting, industrial entrepreneurs were able to mechanize labor, which allowed for a host of new efficiencies such as division of labor, mass production, and global distribution. You'll discover the science behind some of the most astounding inventions in modern history, including the spinning jenny, the incandescent light bulb, and the computer processor. You'll learn how these inventions came about and consider what effects these technologies had on every aspect of human life. Get an inside look at the history of industrial innovation and explore the lives of engineers, inventors, architects, and designers responsible for changing the world - as well as ordinary workers who lost their livelihoods to new technologies and suffered from unsafe working conditions. The story of the Industrial Revolution is complex, and these lectures will leave you with a new appreciation for the amazing human achievements all around us.

    For centuries, royal families have feared the gut-roiling, vomit-inducing agony of a little something added to their food or wine by an enemy. To avoid poison, they depended on tasters, unicorn horns, and antidotes tested on condemned prisoners. Servants licked the royal family’s spoons, tried on their underpants and tested their chamber pots.Ironically, royals terrified of poison were unknowingly poisoning themselves daily with their cosmetics, medications, and filthy living conditions. Women wore makeup made with mercury and lead. Men rubbed turds on their bald spots. Physicians prescribed mercury enemas, arsenic skin cream, drinks of lead filings, and potions of human fat and skull, fresh from the executioner. The most gorgeous palaces were little better than filthy latrines. Gazing at gorgeous portraits of centuries past, we don’t see what lies beneath the royal robes and the stench of unwashed bodies; the lice feasting on private parts; and worms nesting in the intestines.In The Royal Art of Poison, Eleanor Herman combines her unique access to royal archives with cutting-edge forensic discoveries to tell the true story of Europe’s glittering palaces: one of medical bafflement, poisonous cosmetics, ever-present excrement, festering natural illness, and, sometimes, murder.

    At the end of the nineteenth century, serial murderer Joseph Vacher, known and feared as "The Killer of Little Shepherds," terrorized the French countryside. He eluded authorities for years--until he ran up against prosecutor Emile Fourquet and Dr. Alexandre Lacassagne, the era's most renowned criminologist. The two men--intelligent and bold--typified the Belle Epoque, a period of immense scientific achievement and fascination with science's promise to reveal the secrets of the human condition. With high drama and stunning detail, Douglas Starr revisits Vacher's infamous crime wave, interweaving the story of how Lacassagne and his colleagues were developing forensic science as we know it. We see one of the earliest uses of criminal profiling, as Fourquet painstakingly collects eyewitness accounts and constructs a map of Vacher's crimes. We follow the tense and exciting events leading to the murderer's arrest. And we witness the twists and turns of the trial, celebrated in its day. In an attempt to disprove Vacher's defense by reason of insanity, Fourquet recruits Lacassagne, who in the previous decades had revolutionized criminal science by refining the use of blood-spatter evidence, systematizing the autopsy, and doing groundbreaking research in psychology. Lacassagne's efforts lead to a gripping courtroom denouement. "The Killer of Little Shepherds" is an important contribution to the history of criminal justice, impressively researched and thrillingly told.

    To the right listener, they tell us all about themselves: where they came from, how they lived, how they died - and who killed them. Forensic scientists can unlock the mysteries of the past and help justice to be done using the messages left by a corpse, a crime scene or the faintest of human traces. Forensics uncovers the secrets of forensic medicine, drawing on interviews with top-level professionals, ground-breaking research and Val McDermid's own experience to lay bare the secrets of this fascinating science. And, along the way, she wonders at how maggots collected from a corpse can help determine time of death, how a DNA trace a millionth the size of a grain of salt can be used to convict a killer and how a team of young Argentine scientists led by a maverick American anthropologist uncovered the victims of a genocide.In her crime novels, Val McDermid has been solving complex crimes and confronting unimaginable evil for years. Now, she's looking at the people who do it for real, and real crime scenes. It's a journey that will take her to war zones, fire scenes and autopsy suites, and bring her into contact with extraordinary bravery and wickedness, as she traces the history of forensics from its earliest beginnings to the cutting-edge science of the modern day.

    There is no better way to study the big questions in philosophy than to compare how the world's greatest minds have analyzed these questions, defined the terms, and then reasoned out potential solutions. Once you've compared the arguments, the final step is always deciding for yourself whether you find an explanation convincing.This course gives you the tools to follow and create logical arguments while exploring famous philosophers' viewpoints on these important questions. Although progress has been made toward answers, brilliant thinkers have continued to wrestle with many big questions that inspire thoughtful people everywhere. These questions include: What is knowledge? Does God exist? Do humans have free will? What is right and wrong? How should society be organized?Given the complexity of these big questions, it should be no surprise that many controversies are far from settled. In fact, by the end of these 36 lectures, you may be even less sure of the right answers to some of the questions than you were at the beginning. But being a philosopher means constantly testing your views - giving a reasoned defense if you believe you are right and modifying your ideas when you realize you are wrong. You'll discover that great thinkers before you have offered convincing answers to hard questions, philosophers after them have made equally persuasive objections, and then still others have refined the debate even further - causing the issues to come into sharper and sharper focus.Join Plato, St. Anselm, Descartes, Locke, Hume, Kant, Mill, Smith, Marx, Rawls, and many others in an exploration of fundamental questions. Get ready to think big!

    While most of us associate this top-secret subject with popular fiction and film, its true story is more fascinating, surprising, and important than you could possibly imagine. These 24 thrilling lectures survey how world powers have attempted to work in the shadows to gain secret information or subvert enemies behind the scenes. Filled with stories and insights that will change the way you think about world history's most defining events, this course lets you peer inside a subject whose truths most people are unaware of. Professor Liulevicius introduces you to the inner workings of covert organizations, including the Oprichnina, a feared secret service established by tsar Ivan the Terrible in the 1500s in an effort to cleanse Russia of treasonous activities; the CIA, established in 1947 by President Truman to replace the Office of Secret Services to be in charge of all intelligence collection - and which had an embarrassing early history; and Mossad, Israel's version of the CIA, which won a series of key intelligence victories during the cold war and over terror attacks and hostage crises in the second half of the 20th century. You'll also meet famous - and infamous - spies, including Sir Francis Walsingham, Mata Hari, and Kim Philby. In this stirring series of lectures, you'll study the psychological motives behind spies, the ethics of cyber warfare and corporate espionage, the question of whether we now live in a surveillance society, and more.

    supreme court history

    Clear Science Teaching to Set the Stage for an Awe-Inspiring Course Created for a lay audience and readily accessible, in this course science always takes precedence over drama. The lectures are certainly entertaining, often funny, even awe-inspiring at times, as befits the subject matter. Even though you will be entertained, you will be learning good science. Clear introductions to essential principles of physics support these lectures, including density, quantum theory, gravity, and the General Theory of Relativity. Professor Neil deGrasse Tyson also includes forays into disciplines such as chemistry and biology as needed to explain events in astronomy. For example, Dr. Tyson begins one lecture at a point 13 billion years ago, when all space, matter, and energy in the known universe were contained in a volume less than one-trillionth the size of a pinpoint-about the size of a single atom. By the time he finishes, the cosmos has been stretched, the planets and our Earth formed, and 70 percent of existing Earth species have been wiped out by a gigantic asteroidclearing the way for the evolution of humanity. Along the way he has touched on Einstein's famous equation, E=mc2; on the four forces that were once unified in the early cosmos in a way physicists are still trying to explain; and on the chemical enrichment of the universe by exploding supernovae, which give the universe its necessary supply of heavier elements including oxygen, nitrogen, iron and, most important, carbon. Carbon, we learn, is a "sticky" atom, capable of making more kinds of molecules than all other elements combined. It's the ideal element with which to experiment in the building of life forms and is, of course, the element responsible for the remarkable diversity of life, including us. As Dr. Tyson notes, we are made of stardust, just as the planets are. And he has created a course that explains exactly how that came to be, beginning with a grounding in the basic "machinery" of matter, forces, and energy that has been discovered on Earth and which also reveals itself throughout the universe. The Stark and Violent Beauty of the Universe With this basic foundation in place, explanations of cosmic events fall logically into place, and the realities of the universe-including its eventual demise-are revealed in stark and often violent beauty. You learn: how Saturn's rings were formed, and why they will eventually be lost why low-density conditions are necessary to produce the drama of the northern and southern auroras why even the most jagged and wild of the Earth's mountain ranges are, from a cosmic standpoint, really part of a perfectly smooth sphere how black holes are formed and the extraordinary way in which they can wreak havoc in the universe how asteroids moving through space represent threats of extraordinary consequence to Earth, no matter how long those threats may take to be realized why the seemingly infinite panorama of celestial bodies revealed by the Hubble Space Telescope's famous "Deep Field" so intrigued astronomers how astronomers actually look for new planets, why the odds seem overwhelmingly in favor of some kind of life out there, whether we ever make contact or not. Most important, none of these ideas are presented as isolated "space factoids" that serve no purpose but to entertain. They are there to illustrate and reinforce the key principles of physics and astrophysics that are continually being presented in this course. But the inclusion of real science doesn't prevent Dr. Tyson from having some fun, either. When it's time to show how a black hole might remove one from the universe, he leads you right up to the "event horizon" and slips you in-feet first. Since the event horizon represents the point within which nothing, not even light, can escape, you might think this is a bad idea. And you would be right. But as you plummet toward the "singularity" at the heart of the black hole, you will learn firsthand about the interesting effects of gravity truly unleashed, including what physicists refer to, with a straight face, as "spaghettification." (Actually, Professor Tyson recommends that you be sucked in to a large black hole rather than a small one. You'll still be spaghettified, but it won't happen as quickly.) But make no mistake: Dr. Tyson does not consider the cosmos a laughing matter, this kind of whimsical touch notwithstanding. In spite of his training, he remains, admittedly, still in awe of his subject. And he has created a course that might well produce the same feeling in you.

    But sometimes, when obsession gets the better of scientists, they twist a noble pursuit into something sinister. Under this spell, knowledge isn’t everything, it’s the only thing—no matter the cost. Bestselling author Sam Kean tells the true story of what happens when unfettered ambition pushes otherwise rational men and women to cross the line in the name of science, trampling ethical boundaries and often committing crimes in the process.The Icepick Surgeon masterfully guides the reader across two thousand years of history, beginning with Cleopatra’s dark deeds in ancient Egypt. The book reveals the origins of much of modern science in the transatlantic slave trade of the 1700s, as well as Thomas Edison’s mercenary support of the electric chair and the warped logic of the spies who infiltrated the Manhattan Project. But the sins of science aren’t all safely buried in the past. Many of them, Kean reminds us, still affect us today. We can draw direct lines from the medical abuses of Tuskegee and Nazi Germany to current vaccine hesitancy, and connect icepick lobotomies from the 1950s to the contemporary failings of mental-health care. Kean even takes us into the future, when advanced computers and genetic engineering could unleash whole new ways to do one another wrong.Unflinching, and exhilarating to the last page, The Icepick Surgeon fuses the drama of scientific discovery with the illicit thrill of a true-crime tale. With his trademark wit and precision, Kean shows that, while science has done more good than harm in the world, rogue scientists do exist, and when we sacrifice morals for progress, we often end up with neither.

    Writing with award-winning partner Mark Olshaker for the first time since his retirement, Douglas opens up about his most notorious and baffling cases—and shows what it's like to confront evil in its most monstrous form.No one is better acquainted with the subject of humanity’s most notorious crimes and the wrenching challenges of bringing those criminals to justice than John Douglas, the model for Agent Jack Crawford in The Silence of the Lambs. In this provocative and deeply personal book, the most prominent criminal investigator of our time recounts his twenty-five year FBI career tracking down master criminals, write true crime bestsellers, developing forensic science and the art of criminal profiling, but previously he could never be as forthright as he is in this, his first book since retirement. In his previous works, he wrote only about the guilty; in Law & Disorder, he writes about the guilty, innocents accused, and even innocents convicted as he addresses every law enforcement professional’s worst nightmare: those cases where, for one reason or another, justice was delayed…or even denied.A deep glimpse into the mind of a man who has explored the heart of human darkness, he looks to unlock for his readers the ultimate mystery of depravity and the techniques and approaches that have countered evil in the name of justice throughout his career. “An essential title for those interested in true crime stories, forensic science, or law enforcement.”- Library Journal (starred review)"At his best describing terrible crimes." – Houston Chronicle "A real genius." – Entertainment Weekly "Douglas can claim a rare authenticity regarding the evil that men do." - Kirkus Reviews “An essential title for those interested in true crime stories, forensic science, or law enforcement.” - Library Journal (starred review)