By extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and create a coherent framework through which non-expert readers may approach the subject. Written in clear and concise language, and beautifully illustrated, the book is enjoyable to read, and it provides a clear sense of the excitement of modern biology. Molecular Biology of the Cell sets forth the current understanding of cell biology (completely updated as of Autumn 2001), and it explores the intriguing implications and possibilities of the great deal that remains unknown. The hallmark features of previous editions continue in the Fourth Edition. The book is designed with a clean and open, single-column layout. The art program maintains a completely consistent format and style, and includes over 1,600 photographs, electron micrographs, and original drawings by the authors. Clear and concise concept headings introduce each section. Every chapter contains extensive references. Most important, every chapter has been subjected to a rigorous, collaborative revision process where, in addition to incorporating comments from expert reviewers, each co-author reads and reviews the other authors' prose. The result is a truly integrated work with a single authorial voice. Features : - Places the latest hot topics sensibly in context - including genomics, protein structure, array technology, stem cells and genetics diseases. - Incorporates and emphasises new genomic data. - All of molecular biology is brought together into one section (chapters 4-7) covering classically defined molecular biology and molecular genetics. - Two chapters deal exclusively with methods and contain information on the latest tools and techniques. - New chapters on "Pathogens, Infection, and Innate Immunity". - Cell Biology Interactive CD-ROM is packaged with every copy of the book. - Contains over 1,600 illustrations, electron micrographs and photographs, of which over 1,000 are originally conceived by the authors.

    In short, he traverses all of Asia top to bottom, and end to end. In the three decades since he first travelled this route, Asia has undergone phenomenal change. The Soviet Union has collapsed, China has risen, India booms, Burma slowly smothers, and Vietnam prospers despite the havoc unleashed upon it the last time Theroux passed through. He witnesses all this and so much more in a 25,000 mile journey, travelling as the locals do, by train, car, bus, and foot.His odyssey takes him from Eastern Europe, still hungover from Communism, through tense but thriving Turkey, into the Caucasus, where Georgia limps back toward feudalism while its neighbour Azerbaijan revels in oil-driven capitalism. As he penetrates deeper into Asia’s heart, his encounters take on an otherworldly cast. The two chapters that follow show us Turkmenistan, a profoundly isolated society at the mercy of an almost comically egotistical dictator, and Uzbekistan, a ruthless authoritarian state. From there, he retraces his steps through India, Mayanmar, China, and Japan, providing his penetrating observations on the changes these countries have undergone.Brilliant, caustic, and totally addictive, Ghost Train to the Eastern Star is Theroux at his very best.

    It's weirder than we are capable of imagining. And we're all in it together: humans, blue whales, rats, birds of paradise, ridiculous numbers of beetles, molluscs the size of a bus, the sexual gladiators of slugs, bdelliod rotifers who haven't had sex for millions of years and creatures called water bears: you can boil them, freeze them and fire them off into space without killing themWe're all part of the animal kingdom, appearing in what Darwin called 'endless forms most beautiful and most wonderful'. In this breathtakingly audacious book Simon Barnes has brought us all together, seeking not what separates us but what unites us. He takes us white-water rafting through the entire animal kingdom in a book that brings in deep layers of arcane knowledge, the works of Darwin and James Joyce, Barnes's own don't-try-this-at-home adventures in the wild, David Attenborough and Sherlock Holmes.

    Tensions sometimes flared, but tolerance largely prevailed until the twentieth century when the Greek army marched in, Muslims were forced out, and the Nazis deported and killed the Jews. As the acclaimed historian Mark Mazower follows the city’s inhabitants through plague, invasion, famine, and the disastrous twentieth century, he resurrects a fascinating and vanished world.

    By examining fossils and DNA, Shubin shows us that our hands actually resemble fish fins, our head is organized like that of a long-extinct jawless fish, and major parts of our genome look and function like those of worms and bacteria.Shubin makes us see ourselves and our world in a completely new light. Your Inner Fish is science writing at its finest-enlightening, accessible, and told with irresistible enthusiasm.

    Watching over his sleeping son, the father reflects on the dangerous sea-crossing that lies before them. It is also a vivid portrait of their life in Homs, Syria, before the war, and of that city's swift transformation from a home into a deadly war zone. Impelled to write this story by the haunting image of young Alan Kurdi, the three-year-old Syrian boy whose body washed upon the beach in Turkey in September 2015, Hosseini hopes to pay tribute to the millions of families, like Kurdi's, who have been splintered and forced from home by war and persecution, and he will donate author proceeds from this book to the UNHCR (the UN Refugee Agency) and The Khaled Hosseini Foundation to help fund lifesaving relief efforts to help refugees around the globe. Hosseini is also a Goodwill Envoy to the UNHCR, and the founder of The Khaled Hosseini Foundation, a nonprofit that provides humanitarian assistance to the people of Afghanistan.

    

    Boatwright, Daniel Gargola, and Richard J.A. Talbert explore this question as they guide readers through a comprehensive sweep of Roman history, ranging from the prehistoric settlements to the age of Constantine. Vividly written and accessible, The Romans traces Rome's remarkable evolution from village, to monarchy, to republic, and eventually to one-man rule by an emperor whose power at its peak stretched from Scotland to Iraq and the Nile Valley. Firmly grounded in ancient literary and material sources, the book describes and analyzes major political and military landmarks, from the Punic Wars, to Caesar's conquest of Gaul and his crossing of the Rubicon, to the victory of Octavian over Mark Antony, and to Constantine's adoption of Christianity. It also introduces such captivating individuals as Hannibal, Mithridates, Pompey, Cicero, Cleopatra, Augustus, Livia, Nero, Marcus Aurelius, and Shapur. The authors cover issues that still confront modern states worldwide, including warfare, empire building, consensus forging, and political fragmentation. They also integrate glimpses of many aspects of everyday Roman life and perspective--such as the role of women, literature, entertainment, town-planning, portraiture, and religion--demonstrating how Rome's growth as a state is inseparable from its social and cultural development. Ideal for courses in Roman history and Roman civilization, The Romans is enhanced by almost 100 illustrations, more than 30 maps (most produced by the Ancient World Mapping Center), and 22 textual extracts that provide fascinating cultural observations made by ancient Romans themselves.

    An exciting revision of this innovative text, Earth: Portrait of a Planet, Third Edition, emphasizes active student learning with a new chapter format, interactive media, and the power and insight of Google Earth .

    While apocalyptic weather patterns destroyed entire harvests and incited mass migrations, they gave rise to the growth of European cities, the emergence of early capitalism, and the vigorous stirrings of the Enlightenment. A timely examination of how a society responds to profound and unexpected change, Nature’s Mutiny will transform the way we think about climate change in the twenty-first century and beyond.

    This powerful anthology gathers the passionate voices of young writers who have grown up in an environmentally damaged and compromised world. Each contributor has come of age since Bill McKibben foretold the doom of humanity’s ancient relationship with a pristine earth in his prescient 1988 warning of climate change, The End of Nature.What happens to individuals and societies when their most fundamental cultural, historical, and ecological bonds weaken—or snap? In Coming of Age at the End of Nature, insightful millennials express their anger and love, dreams and fears, and sources of resilience for living and thriving on our shifting planet.Twenty-two essays explore wide-ranging themes that are paramount to young generations but that resonate with everyone, including redefining materialism and environmental justice, assessing the risk and promise of technology, and celebrating place anywhere from a wild Atlantic island to the Arizona desert, to Baltimore and Bangkok. The contributors speak with authority on problems facing us all, whether railing against the errors of past generations, reveling in their own adaptability, or insisting on a collective responsibility to do better.

    Only ours will: our livelihoods, our homes, our cultures. And we're squarely at the tipping point.Longer droughts in the Middle East. Growing desertification in China and Africa. The monsoon season shrinking in India. Amped-up heat waves in Australia. More intense hurricanes reaching America. Water wars in the Horn of Africa. Rebellions, refugees and starving children across the globe. These are not disconnected events. These are the pieces of a larger puzzle that environmental expert Jeff Nesbit puts togetherUnless we start addressing the causes of climate change and stop simply navigating its effects, we will be facing a series of unstoppable catastrophes by the time our preschoolers graduate from college. Our world is in trouble - right now. This Is the Way the World Ends tells the real stories of the substantial impacts to Earth's systems unfolding across each continent. The bad news? Within two decades or so, our carbon budget will reach a point of no return.But there's good news. Like every significant challenge we've faced--from creating civilization in the shadow of the last ice age to the Industrial Revolution--we can get out of this box canyon by understanding the realities, changing the worn-out climate conversation to one that's relevant to every person. Nesbit provides a clear blueprint for real-time, workable solutions we can tackle together.

    Gates says, "we can work on a local, national, and global level to build the technologies, businesses, and industries to avoid the worst impacts of climate change." His interest in climate change is a natural outgrowth of the efforts by his foundation to reduce poverty and disease. Climate change, according to Gates, will have the biggest impact on the people who have done the least to cause it. As a technologist, he has seen first-hand how innovation can change the world. By investing in research, inventing new technologies, and by deploying them quickly at large scale, Gates believes climate change can be addressed in meaningful ways. According to Gates, "to prevent the worst effects of climate change, we have to get to net-zero emissions of greenhouse gases. This problem is urgent, and the debate is complex, but I believe we can come together to invent new carbon-zero technologies, deploy the ones we have, and ultimately avoid a climate catastrophe."

    W. Norton & Company proudly announces an exciting revision of its best-selling Western Civilizations. Used successfully by well over 1,000,000 students, Western Civilizations is renowned for its balanced presentation, clear prose, and exceptional treatment of cultural history. New co-authors Judith Coffin (University of Texas, Austin) and Robert Stacey (University of Washington, Seattle) have reimagined these classic features for today's instructors and students. The new edition emphasizes the changing boundaries of traditional narratives by discussing the West in a wider world context and highlighting the diverse experiences of its peoples and states. Combined with an outstanding pedagogical program, an expanded website, and a new edition of the companion reader Perspectives from the Past, Western Civilzations offers the most complete and accessible package for students.

    Young Lenny Sethi is kept out of school because she suffers from polio. She spends her days with Ayah, her beautiful nanny, visiting with the large group of admirers that Ayah draws. It is in the company of these working class characters that Lenny learns about religious differences, religious intolerance, and the blossoming genocidal strife on the eve of Partition. As she matures, Lenny begins to identify the differences between the Hindus, Moslems, and Sikhs engaging in political arguments all around her. Lenny enjoys a happy, privileged life in Lahore, but the kidnapping of her beloved Ayah signals a dramatic change. Soon Lenny’s world erupts in religious, ethnic, and racial violence. By turns hilarious and heartbreaking, the domestic drama serves as a microcosm for a profound political upheaval.