Alyssa Mastromonaco worked for Barack Obama for almost a decade, and long before his run for president. From the then-senator's early days in Congress to his years in the Oval Office, she made Hope and Change happen through blood, sweat, tears, and lots of briefing binders.But for every historic occasion-meeting the queen at Buckingham Palace, bursting in on secret climate talks, or nailing a campaign speech in a hailstorm-there were dozens of less-than-perfect moments when it was up to Alyssa to save the day. Like the time she learned the hard way that there aren't nearly enough bathrooms at the Vatican.Full of hilarious, never-before-told stories, WHO THOUGHT THIS WAS A GOOD IDEA? is an intimate portrait of a president, a book about how to get stuff done, and the story of how one woman challenged, again and again, what a "White House official" is supposed to look like. Here Alyssa shares the strategies that made her successful in politics and beyond, including the importance of confidence, the value of not being a jerk, and why ultimately everything comes down to hard work (and always carrying a spare tampon).Told in a smart, original voice and topped off with a couple of really good cat stories, WHO THOUGHT THIS WAS A GOOD IDEA? is a promising debut from a savvy political star.

    At the same time, he was immersed in street life. Today he is a cutting-edge neuroscientist—Columbia University's first tenured African American professor in the sciences—whose landmark, controversial research is redefining our understanding of addiction.In this provocative and eye-opening memoir, he recalls his journey of self-discovery and weaves his past and present. Hart goes beyond the hype of the antidrug movement as he examines the relationship among drugs, pleasure, choice, and motivation, both in the brain and in society. His findings shed new light on common ideas about race, poverty, and drugs, and explain why current policies are failing.Though Hart escaped neighborhoods that were dominated by entrenched poverty and the knot of problems associated with it, he has not turned his back on his roots. Determined to make a difference, he tirelessly applies his scientific research to help save real lives. But balancing his former street life with his achievements today has not been easy—a struggle he reflects on publicly for the first time.A powerful story of hope and change, of a scientist who has dedicated his life to helping others, High Price will alter the way we think about poverty, race, and addiction—and how we can effect change.

    Now they explore the compulsion through a series of compelling case studies in the vein of Oliver Sacks. With vivid portraits that show us the traits by which you can identify a hoarder's piles on sofas and beds that make the furniture useless, houses that can be navigated only by following small paths called goat trails, vast piles of paper that the hoarders "churn" but never discard, even collections of animals and garbage; Frost and Steketee illuminate the pull that possessions exert on all of us. Whether we're savers, collectors, or compulsive cleaners, very few of us are in fact free of the impulses that drive hoarders to the extremes in which they live. For all of us with complicated relationships to our things, Stuff answers the question of what happens when our stuff starts to own us.

    After a privileged yet emotionally-starved childhood in Washington, she became hooked on ADHD medication provided by her psychiatrist father. This led to a dependence on Xanax and other prescription drugs at boarding school, and she experimented with cocaine, ecstasy… whatever came her way. By 26 she was a talented ‘doctor shopper’ who manipulated Upper East Side psychiatrists into giving her never-ending prescriptions; her life had become a twisted merry-go-round of parties and pills at night, and trying to hold down a high profile job at Condé Naste during the day.With a complete lack of self-pity and an honesty that is almost painful, Cat describes the crazed euphoria, terrifying comedowns and the horrendous guilt she feels lying to those who try to help her. Writing in a voice that is utterly magnetic – prompting comparisons to Brett Easton Ellis and Charles Bukowski – she captures something essential both about her generation and our times. Profoundly divisive and controversial, How to Murder Your Life is a unforgettable, charged account of a young female addict, so close to throwing her entire life away.

    As Dr. Kent Kiehl shows, psychopaths can be identified by a checklist of symptoms that includes pathological lying; lack of empathy, guilt, and remorse; grandiose sense of self-worth; manipulation; and failure to accept one’s actions. But why do psychopaths behave the way they do? Is it the result of their environment— how they were raised—or is there a genetic compo­nent to their lack of conscience? This is the question Kiehl, a protégé of famed psychopath researcher Dr. Robert Hare, was deter­mined to answer as he began his career twenty years ago. To aid in his quest to unravel the psy­chopathic mind, Kiehl created the first mobile functional MRI scanner to study psychopaths in prison populations. The brains of more than five hundred psychopaths and three thousand other offenders have been scanned by Kiehl’s labora­tory—the world’s largest forensic neuroscience repository of its kind. Over the course of The Psy­chopath Whisperer, we follow the scientific bread crumbs that Kiehl uncovered to show that the key brain structures that correspond with emotional engagement and reactions are diminished in psy­chopaths, offering new clues to how to predict and treat the disorder. In The Psychopath Whisperer, Kiehl describes in fascinating detail his years working with psy­chopaths and studying their thought processes— from the remorseless serial killers he meets with behind bars to children whose behavior and per­sonality traits exhibit the early warning signs of psychopathy. Less than 1 percent of the general population meets the criteria for psychopathy. But psycho­paths account for a vastly outsized proportion of violent crimes. And as Kiehl shows, many who aren’t psychopaths exhibit some of the behaviors and traits associated with the condition. What do you do if you discover your roommate, or boss, or the person you are dating has traits that define a psy­chopath? And what does having a diminished limbic region of the brain mean for how the legal system approaches crimes committed by psychopaths? A compelling narrative of cutting-edge science, The Psychopath Whisperer will open your eyes on a fascinating but little understood world, with startling implications for society, the law, and our personal lives.

    That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer research—the Philadelphia chromosome. This book charts not only that landmark discovery, but also—for the first time, all in one place—the full sequence of scientific and medical discoveries that brought about the first-ever successful treatment of a lethal cancer at the genetic level.The significance of this mutant chromosome would take more than three decades to unravel; in 1990, it was recognized as the sole cause of a deadly blood cancer, chronic myeloid leukemia, or CML. This dramatic discovery launched a race involving doctors and researchers around the world, who recognized that in principle it might be possible to target CML at its genetic source.Science journalist Jessica Wapner brings extensive original reporting to this book, including interviews with more than thirty-five people with a direct role in this story. Wapner reconstructs more than forty years of crucial breakthroughs, clearly explains the science behind them, and pays tribute to the dozens of researchers, doctors, and patients whose curiosity and determination restored the promise of a future to the more than 70,000 people worldwide who are diagnosed with CML each year. Chief among them is researcher and oncologist Dr. Brian Druker, whose dedication to his patients fueled his quest to do everything within his power to save them.The Philadelphia Chromosome helps us to fully understand and appreciate just how pathbreaking, hard-won, and consequential are the achievements it recounts—and to understand the principles behind much of today’s most important cancer research, as doctors and scientists race to uncover and treat the genetic roots of a wide range of cancers.

    Enduring half a dozen surgeries, the drugs he received were both miraculous and essential to his recovery. But his most profound suffering came several months later when he went into acute opioid withdrawal while following his physician’s orders. Over the course of four excruciating weeks, Rieder learned what it means to be “dope sick”—the physical and mental agony caused by opioid dependence. Clueless how to manage his opioid taper, Travis’s doctors suggested he go back on the drugs and try again later. Yet returning to pills out of fear of withdrawal is one route to full-blown addiction. Instead, Rieder continued the painful process of weaning himself.Rieder’s experience exposes a dark secret of American pain management: a healthcare system so conflicted about opioids, and so inept at managing them, that the crisis currently facing us is both unsurprising and inevitable. As he recounts his story, Rieder provides a fascinating look at the history of these drugs first invented in the 1800s, changing attitudes about pain management over the following decades, and the implementation of the pain scale at the beginning of the twenty-first century. He explores both the science of addiction and the systemic and cultural barriers we must overcome if we are to address the problem effectively in the contemporary American healthcare system.In Pain in America is not only a gripping personal account of dependence, but a groundbreaking exploration of the intractable causes of America’s opioid problem and their implications for resolving the crisis. Rieder makes clear that the opioid crisis exists against a backdrop of real, debilitating pain—and that anyone can fall victim to this epidemic.

    

    "What happens when we die? Does the light just go out and that's that—the million-year nap? Or will some part of my personality, my me-ness persist? What will that feel like? What will I do all day? Is there a place to plug in my lap-top?" In an attempt to find out, Mary Roach brings her tireless curiosity to bear on an array of contemporary and historical soul-searchers: scientists, schemers, engineers, mediums, all trying to prove (or disprove) that life goes on after we die.

    The result is this stunning memoir. Featuring 78 poems, 78 essays and intimate family photographs, Alexie shares raw, angry, funny, profane, tender memories of a childhood few can imagine--growing up dirt-poor on an Indian reservation, one of four children raised by alcoholic parents. Throughout, a portrait emerges of his mother as a beautiful, mercurial, abusive, intelligent, complicated woman. You Don't Have To Say You Love Me is a powerful account of a complicated relationship, an unflinching and unforgettable remembrance.

    For Melody Warnick, it was move #6, from Austin, Texas, to Blacksburg, Virginia, that threatened to unhinge her. In the lonely aftermath of unpacking, she wondered: Aren’t we supposed to put down roots at some point? How does where we live become the place where we want to stay? This time, she had an epiphany. Rather than hold her breath and hope this new town would be her family’s perfect fit, she would figure out how to fall in love with it—no matter what. How we come to feel at home in our towns and cities is what Warnick sets out to discover in This Is Where You Belong. She dives into the body of research around place attachment—the deep sense of connection that binds some of us to our cities and increases our physical and emotional well-being—then travels to towns across America to see it in action. Inspired by a growing movement of placemaking, she examines what its practitioners are doing to create likeable locales. She also speaks with frequent movers and loyal stayers around the country to learn what draws highly mobile Americans to a new city, and what makes us stay. The best ideas she imports to her adopted hometown of Blacksburg for a series of Love Where You Live experiments designed to make her feel more locally connected. Dining with her neighbors. Shopping Small Business Saturday. Marching in the town Christmas parade. Can these efforts make a halfhearted resident happier? Will Blacksburg be the place where she finally stays? What Warnick learns will inspire you to embrace your own community—and perhaps discover that the place where you live right now is home.

    This is a book for anyone who has ever failed. Which means it’s a book for everyone. If I have learned one thing from this shockingly beautiful venture called life, it is this: failure has taught me lessons I would never otherwise have understood. I have evolved more as a result of things going wrong than when everything seemed to be going right. Out of crisis has come clarity, and sometimes even catharsis.Part memoir, part manifesto, and including chapters on dating, work, sport, babies, families, anger and friendship, it is based on the simple premise that understanding why we fail ultimately makes us stronger. It's a book about learning from our mistakes and about not being afraid. Uplifting, inspiring and rich in stories from Elizabeth’s own life, How to Fail reveals that failure is not what defines us; rather it is how we respond to it that shapes us as individuals. Because learning how to fail is actually learning how to succeed better. And everyone needs a bit of that.

    By combining analysis of the historical evidence with the latest psychiatric research, Ghaemi demonstrates how he thinks these qualities have produced brilliant leadership under the toughest circumstances.individuals and society at large-however high the price for those who endure these illnesses.

    The pieces range from long meditations on topics like loneliness and being an outsider, to short humor pieces, conversations, and memorable one-liners.Jonny's honest writings about his struggles with feeling productive, as well as his difficulties with anxiety and depression will connect deeply with his fans as well as anyone attempting to create in our chaotic world. It also features a recipe for scrambled eggs that might make you cry.

    Trump and the toxic family that made him, Mary L. Trump, a trained clinical psychologist and Donald’s only niece, shines a bright light on the dark history of their family in order to explain how her uncle became the man who now threatens the world’s health, economic security, and social fabric.Mary Trump spent much of her childhood in her grandparents’ large, imposing house in the heart of Queens, where Donald and his four siblings grew up. She describes a nightmare of traumas, destructive relationships, and a tragic combination of neglect and abuse. She explains how specific events and general family patterns created the damaged man who currently occupies the Oval Office, including the strange and harmful relationship between Fred Trump and his two oldest sons, Fred Jr. and Donald.A first-hand witness to countless holiday meals and family interactions, Mary brings an incisive wit and unexpected humor to sometimes grim, often confounding family events. She recounts in unsparing detail everything from her uncle Donald’s place in the family spotlight and Ivana’s penchant for re-gifting to her grandmother’s frequent injuries and illnesses and the appalling way Donald, Fred Trump’s favorite son, dismissed and derided him when he began to succumb to Alzheimer’s.Numerous pundits, armchair psychologists, and journalists have sought to parse Donald J. Trump’s lethal flaws. Mary L. Trump has the education, insight, and intimate familiarity needed to reveal what makes Donald, and the rest of her clan, tick. She alone can recount this fascinating, unnerving saga, not just because of her insider’s perspective but also because she is the only Trump willing to tell the truth about one of the world’s most powerful and dysfunctional families.