Relativity and quantum physics touch the very basis of physical reality, altering our commonsense notions of space and time, cause and effect. Both have reputations for complexity. But the basic ideas behind relativity and quantum physics are, in fact, simple and comprehensible by anyone. As Professor Wolfson points out, the essence of relativity can be summed up in a single sentence: The laws of physics are the same for all observers in uniform motion. The same goes for quantum theory, which is based on the principle that the "stuff " of the universe-matter and energy-is not infinitely divisible but comes in discrete chunks called "quanta." Profound ... Beautiful ... Relevant Why should you care about these landmark theories? Because relativity and quantum physics are not only profound and beautiful ideas in their own right, they are also the gateway to understanding many of the latest science stories in the media. These are the stories about time travel, string theory, black holes, space telescopes, particle accelerators, and other cutting-edge developments. Consider these ideas: Although Einstein's theory of general relativity dates from 1914, it has not been possible to test certain predictions until recently. The Hubble Space Telescope is providing some of the most striking confirmations of the theory, including certain evidence for the existence of black holes, objects that warp space and time so that not even light can escape. Also, the expansion of the universe predicted by the theory of general relativity is now a known rate. General relativity also predicts an even weirder phenomenon called "wormholes" that offer shortcuts to remote reaches of time and space. According to Einstein's theory of special relativity, two twins would age at different rates if one left on a high-speed journey to a distant star and then returned. This experiment has actually been done, not with twins, but with an atomic clock flown around the world. Another fascinating experiment confirming that time slows as speed increases comes from measuring muons at the top and bottom of mountains. A seemingly absurd consequence of quantum mechanics, called "quantum tunneling," makes it possible for objects to materialize through impenetrable barriers. Quantum tunneling happens all the time on the subatomic scale and plays an important role in electronic devices and the nuclear processes that keep the sun shining. Some predictions about the expansion of the universe were so odd that Einstein himself tried to rewrite the mathematics in order to eliminate them. When Hubble discovered the expansion of the universe, Einstein called the revisions the biggest mistake he had ever made. An intriguing thought experiment called "Schrödinger's cat" suggests that a cat in an enclosed box is simultaneously alive and dead under experimental conditions involving quantum phenomena. From Aristotle to the Theory of Everything Professor Wolfson begins with a brief overview of theories of physical reality starting with Aristotle and culminating in Newtonian or "classical" physics. Then he outlines the logic that led to Einstein's theory of special relativity, and the simple yet far-reaching insight on which it rests. With that insight in mind, you move on to consider Einstein's theory of general relativity and its interpretation of gravitation in terms of the curvature of space and time. Professor Wolfson then shows how inquiry into matter at the atomic and subatomic scales led to quandaries that are resolved-or at least clarified-by quantum mechanics, a vision of physical reality so at odds with our experience that it nearly defies language. Bringing relativity and quantum mechanics into the same picture leads to hypotheses about the origin, development, and possible futures of the entire universe, and the possibility that physics can produce a "theory of everything" to account for all aspects of the physical world. Fascinating Incidents and Ideas Along the way, you'll explore these fascinating incidents and ideas: In the 1880s, Albert Michelson and Edward Morley conducted an experiment to determine the motion of the Earth relative to the ether, which was a supposedly imponderable substance pervading all of space. You'll learn about their experiment, its shocking result, and the resulting theoretical crisis. In 1905, a young Swiss patent clerk named Albert Einstein resolved the crisis by discarding the ether concept and asserting the principle of relativity-that the laws of physics are the same for all observers in uniform motion. Relativity implies that the time order of events can be different in different reference frames. Does this wreak havoc with cause and effect? And why does Einstein assert that nothing can go faster than light? Shortly after publishing his 1905 paper on special relativity, Einstein realized that his theory required a fundamental equivalence between mass and energy, which he expressed in the equation E=mc2. Among other things, this famous formula means that the energy contained in a single raisin could power a large city for a whole day. Historically, the path to general relativity followed Einstein's attempt to incorporate gravity into relativity theory, which led to his understanding of gravity not as a force, but as a local manifestation of geometry in curved spacetime. Quantum theory places severe limits on our ability to observe nature at the atomic scale because it implies that the act of observation necessarily disturbs the thing that is being observed. The result is Werner Heisenberg's famous "uncertainty principle." Are quarks, the particles that make up protons and neutrons, the truly elementary particles? What are the three fundamental forces that physicists identify as holding particles together? Could they be manifestations of a single, universal force? A Teaching Legend On his own Middlebury College campus, Professor Wolfson is a teaching legend with an infectious enthusiasm for his subject and a knack for conveying difficult concepts in a way that fosters true understanding. He is the author of an introductory text on physics, a contributor to the esteemed publication Scientific American, and a specialist in interpreting science for the nonspecialist. In this course, Professor Wolfson uses extensive illustrations and diagrams to help bring to life the theories and concepts that he discusses. Thus we highly recommend our DVD version, although Professor Wolfson is mindful of our audio students and carefully describes visual materials throughout his lectures. Professor Richard Wolfson on the Second Edition of Einstein's Relativity: "The first version of this course was produced in 1995. In this new version, I have chosen to spend more time on the philosophical interpretation of quantum physics, and on recent experiments relevant to that interpretation. I have also added a final lecture on the theory of everything and its possible implementation through string theory. The graphic presentations for the DVD version have also been extensively revised and enhanced. But the goal remains the same: to present the key ideas of modern physics in a way that makes them clear to the interested layperson."

    Some of their responses to those outbreaks are almost too strange to believe in hindsight. Get Well Soon delivers the gruesome, morbid details of some of the worst plagues we’ve suffered as a species, as well as stories of the heroic figures who selflessly fought to ease the suffering of their fellow man. With her signature mix of in-depth research and storytelling, and not a little dark humor, Jennifer Wright explores history’s most gripping and deadly outbreaks, and ultimately looks at the surprising ways they’ve shaped history and humanity for almost as long as anyone can remember.

    But they've often been hidden in plain sight, their inventions and contributions touching our lives in ways we don't even realize.Author Claire L. Evans finally gives these unsung female heroes their due with her social history of the Broad Band, the women who made the internet what it is today. Learn from Ada Lovelace, the daughter of Lord Byron, who wove numbers into the first program for a mechanical computer in 1842. Seek inspiration from Grace Hopper, the tenacious mathematician who democratized computing by leading the charge for machine-independent programming languages after World War II. Meet Elizabeth "Jake" Feinler, the one-woman Google who kept the earliest version of the Internet online, and Stacy Horn, who ran one of the first-ever social networks on a shoestring out of her New York City apartment in the 1980s. Evans shows us how these women built and colored the technologies we can't imagine life without.Join the ranks of the pioneers who defied social convention and the longest odds to become database poets, information-wranglers, hypertext dreamers, and glass ceiling-shattering dot com-era entrepreneurs.

    We ignore this reality most of the time, but when a new threat (Ebola, SARS, Zika) seems imminent, we send our best and bravest doctors to contain it--people like Dr. Ali S. Khan.In his long career as a public health first responder—protected by a thin mask from infected patients, napping under nets to keep out scorpions, making life-and-death decisions on limited, suspect information—Khan has found that rogue microbes will always be a problem, but outbreaks are often caused by people. We make mistakes, politicize emergencies, and, too often, fail to imagine the consequences of our actions.The Next Pandemic is a firsthand account of disasters like anthrax, bird flu, and others and how we could do more to prevent their return. It's both a gripping story of our brushes with fate and an urgent lesson on how we can keep ourselves safe from the inevitable next pandemic.

    Join renowned neuroscientist David Eagleman for a journey into the questions at the mysterious heart of our existence. What is reality? Who are “you”? How do you make decisions? Why does your brain need other people? How is technology poised to change what it means to be human?  In the course of his investigations, Eagleman guides us through the world of extreme sports, criminal justice, facial expressions, genocide, brain surgery, gut feelings, robotics, and the search for immortality.  Strap in for a whistle-stop tour into the inner cosmos. In the infinitely dense tangle of billions of brain cells and their trillions of connections, something emerges that you might not have expected to see in there: you.

    Manning and his team at NASA's Jet Propulsion Laboratory, tasked with designing a lander many times larger and more complex than any before, faced technical setbacks, fights over inadequate resources, and the challenges of leading an army of brilliant, passionate, and often frustrated experts.Manning's fascinating personal account--which includes information from his exclusive interviews with leading Curiosity scientists--is packed with tales of revolutionary feats of science, technology, and engineering. Readers experience firsthand the disappointment at encountering persistent technical problems, the agony of near defeat, the sense of victory at finding innovative solutions to these problems, the sheer terror of staking careers and reputations on a lander that couldn't be tested on Earth, and the rush of triumph at its successful touchdown on Mars on August 5, 2012. This is the story of persistence, dedication, and unrelenting curiosity.

    She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

    From the emergence of life at deep-sea vents to solar-powered starships sailing through the galaxy, from the Big Bang to the intricacies of intelligence in many life forms, acclaimed author Ann Druyan documents where humanity has been and where it is going, using her unique gift of bringing complex scientific concepts to life. With evocative photographs and vivid illustrations, she recounts momentous discoveries, from the Voyager missions in which she and her husband, Carl Sagan, participated to Cassini-Huygens's recent insights into Saturn's moons. This breathtaking sequel to Sagan's masterpiece explains how we humans can glean a new understanding of consciousness here on Earth and out in the cosmos--again reminding us that our planet is a pale blue dot in an immense universe of possibility.

    A group of young scientists, under the guidance of Dr. George Church, the most brilliant geneticist of our time, works to make fantasy reality by sequencing the DNA of a frozen woolly mammoth harvested from above the Arctic circle, and splicing elements of that sequence into the DNA of a modern elephant. Will they be able to turn the hybrid cells into a functional embryo and bring the extinct creatures to life in our modern world?Along with Church and his team of Harvard scientists, a world-famous conservationist and a genius Russian scientist plan to turn a tract of the Siberian tundra into Pleistocene Park, populating the permafrost with ancient herbivores as a hedge against an environmental ticking time bomb.

    How can it be possible that the world we see is not objective reality? And how can our senses be useful if they are not communicating the truth? Hoffman grapples with these questions and more over the course of this eye-opening work.Ever since Homo sapiens has walked the earth, natural selection has favored perception that hides the truth and guides us toward useful action, shaping our senses to keep us alive and reproducing. We observe a speeding car and do not walk in front of it; we see mold growing on bread and do not eat it. These impressions, though, are not objective reality. Just like a file icon on a desktop screen is a useful symbol rather than a genuine representation of what a computer file looks like, the objects we see every day are merely icons, allowing us to navigate the world safely and with ease.The real-world implications for this discovery are huge. From examining why fashion designers create clothes that give the illusion of a more “attractive” body shape to studying how companies use color to elicit specific emotions in consumers, and even dismantling the very notion that spacetime is objective reality, The Case Against Reality dares us to question everything we thought we knew about the world we see.

    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    It can be microscopic, yet also accounts for the largest organisms ever recorded, living for millennia and weighing tens of thousands of tonnes. Its ability to digest rock enabled the first life on land, it can survive unprotected in space, and thrives amidst nuclear radiation.In this captivating adventure, Merlin Sheldrake explores the spectacular and neglected world of fungi: endlessly surprising organisms that sustain nearly all living systems. They can solve problems without a brain, stretching traditional definitions of ‘intelligence’, and can manipulate animal behaviour with devastating precision. In giving us bread, alcohol and life-saving medicines, fungi have shaped human history, and their psychedelic properties, which have influenced societies since antiquity, have recently been shown to alleviate a number of mental illnesses. The ability of fungi to digest plastic, explosives, pesticides and crude oil is being harnessed in break-through technologies, and the discovery that they connect plants in underground networks, the ‘Wood Wide Web’, is transforming the way we understand ecosystems. Yet they live their lives largely out of sight, and over ninety percent of their species remain undocumented.Entangled Life is a mind-altering journey into this hidden kingdom of life, and shows that fungi are key to understanding the planet on which we live, and the ways we think, feel and behave. The more we learn about fungi, the less makes sense without them.

    The fantastic journey began in 1977, before the first episode of Cosmos aired. The mission was planned as a grand tour beyond the moon; beyond Mars, Jupiter, and Saturn; and maybe even into interstellar space. The fact that it actually happened makes this humanity's greatest space mission.In The Interstellar Age, award-winning planetary scientist Jim Bell reveals what drove and continues to drive the members of this extraordinary team, including Ed Stone, Voyager's chief scientist and the one-time head of NASA's Jet Propulsion Lab; Charley Kohlhase, an orbital dynamics engineer who helped to design many of the critical slingshot maneuvers around planets that enabled the Voyagers to travel so far; and the geologist whose Earth-bound experience would prove of little help in interpreting the strange new landscapes revealed in the Voyagers' astoundingly clear images of moons and planets.Speeding through space at a mind-bending eleven miles a second, Voyager 1 is now beyond our solar system's planets. It carries with it artifacts of human civilization. By the time Voyager passes its first star in about 40,000 years, the gold record on the spacecraft, containing various music and images including Chuck Berry's "Johnny B. Goode," will still be playable.

    From body lotion to tonic water, the popular new element shines bright in the otherwise dark years of the First World War.Meanwhile, hundreds of girls toil amidst the glowing dust of the radium-dial factories. The glittering chemical covers their bodies from head to toe; they light up the night like industrious fireflies. With such a coveted job, these "shining girls" are the luckiest alive—until they begin to fall mysteriously ill.But the factories that once offered golden opportunities are now ignoring all claims of the gruesome side effects, and the women's cries of corruption. And as the fatal poison of the radium takes hold, the brave shining girls find themselves embroiled in one of the biggest scandals of America's early 20th century, and in a groundbreaking battle for workers' rights that will echo for centuries to come.Written with a sparkling voice and breakneck pace, The Radium Girls fully illuminates the inspiring young women exposed to the "wonder" substance of radium, and their awe-inspiring strength in the face of almost impossible circumstances. Their courage and tenacity led to life-changing regulations, research into nuclear bombing, and ultimately saved hundreds of thousands of lives.

    But this is not the whole story.Shedding light on controversial research and investigating the ferocious gender wars in biology, psychology and anthropology, Angela Saini takes readers on an eye-opening journey to uncover how women are being rediscovered. She explores what these revelations mean for us as individuals and as a society, revealing an alternative view of science in which women are included, rather than excluded.