This text provides a basic treatment of discrete-event simulation, including the proper collection and analysis of data, the use of analytic techniques, verification and validation of models, and designing simulation experiments. It offers an up-to-date treatment of simulation of manufacturing and material handling systems, computer systems, and computer networks. Students and instructors will find a variety of resources at the associated website, www.bcnn.net, including simulation source code for download, additional exercises and solutions, web links and errata.

    Science has seen its fair share of punch-ups over the years, but one debate, in the field of biology, has become notorious for its intensity. Over the last twenty years, Richard Dawkins and Stephen Jay Gould have engaged in a savage battle over evolution, which continues to rage even after Gould's death in 2002. Kim Sterelny moves beyond caricature to expose the real differences between the conceptions of evolution of these two leading scientists. He shows that the conflict extends beyond evolution to their very beliefs in science itself; and, in Gould?s case, to domains in which science plays no role at all.

    The author successfully introduces Maxwell's equations, wave propagation, network analysis, and design principles as applied to modern microwave engineering. A considerable amount of material in this book is related to the design of specific microwave circuits and components, for both practical and motivational value. It also presents the analysis and logic behind these designs so that the reader can see and understand the process of applying the fundamental concepts to arrive at useful results. The derivations are well laid out and the majority of each chapter's formulas are displayed in a nice tabular format every few pages. This Third Edition offers greatly expanded coverage with new material on: Noise; Nonlinear effects; RF MEMs; transistor power amplifiers; FET mixers; oscillator phase noise; transistor oscillators and frequency multiplier.

    It uses a taxonomic approach for the study of pathogens.

    She reveals them to be curious, clever connoisseurs of their world, technologically inventive and ecologically adaptable. Above all, they were successful survivors for more than 300,000 years, during times of massive climatic upheaval.At a time when our species has never faced greater threats, we’re obsessed with what makes us special. But, much of what defines us was also in Neanderthals, and their DNA is still inside us. Planning, co-operation, altruism, craftsmanship, aesthetic sense, imagination... perhaps even a desire for transcendence beyond mortality.It is only by understanding them, that we can truly understand ourselves.

     Jammed with sage advice, genuine encouragement, and surprising examples of how to write and how not to write, this book gives beginning writers and confident students alike an easy-to-follow roadmap for improving one of the most important skills for success. En route to Sin Boldly!-induced, A+ paper bliss, readers encounter such topics as:Choosing a Topic and Telling Your Story ("K.I.S.S.-Keep It Simple, Stupid")Literary Games (featuring "Francobabble for Freshman")Choosing a Voice ("Dissing the Prof")Grammatical Horrors ("A does not equal they")Common Mistakes ("Hopefully and Other Controversies") Fully revised and updated with new examples, quizzes, and tips, Sin Boldly! is not only a comprehensive guide, but also a fantastic, fun read for anyone who wants to write clearly and effectively.

    But as animals can only be spied on by getting quite close Heinrich adopts ravens, thereby becoming a "raven father," as well as observing them in their natural habitat, studying their daily routines, and in the process painting a vivid picture of the world as lived by the ravens. At the heart of this book are Heinrich's love and respect for these complex and engaging creatures, and through his keen observation andanalysis, we become their intimates too.Throughout history there has existed an extraordinary relationship between humans and ravens. Ravens, like early humans, are scavengers on the kills of great carnivores. As scavengers, ravens were associated with hunters they found in the north: wolves and, later, men. The trinity of wolf, man, and raven in the hunt is an extremely ancient one. In considering the appeal of the raven, Bernd Heinrich suspects that a meeting of the minds might reside in that hunting trinity.Heinrich's passion for ravens has led him around the world in his research. Mind of the Raven takes you on an exotic journey--from New England to Germany, Montana to Baffin Island in the high Arctic--offering dazzling accounts of how science works in the field, filtered through the eyes of a passionate observer of nature.Heinrich has a true gift; through his stories, his beautiful writing, illustrations, and photography, the ravens come alive. Each new discovery and insight into their behavior is thrilling to read. just as the title promises, the reader is given a rare glimpse into the mind of these wonderful creatures.Following the dictum of Leonardo da Vinci--"It is not enough to believe what you see. YOU Must also understand what you see"--Bernd Heinrich enables us to see the natural world through the eyes of a scientist. At once lyrical and scientific, Mind of the Raven is bound to be a modern classic.

    The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.Janeway s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout that of the host s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.New in the Eighth EditionInnate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook. Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes). The section on complement has been reworked and reconceived explaining the lectin pathway first making it easier to teach by placing it into the context of innate recognition. Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms. The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book. Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen. Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria. Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways. Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines. Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text. The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways. New references have been added throughout the text.

    This thorough revision provides a survey by groups, emphasizing adaptive morphology and physiology, while covering anatomical ground plans and basic developmental patterns. New co-author Richard Fox brings to the revision his expertise as an ecologist, offering a good balance to Ruppert's background as a functional morphologist. Rich illustrations and extensive citations make the book extremely valuable as a teaching tool and reference source.

    It covers the entire scope of mechanical metallurgy, from an understanding of the continuum description of stress and strain, through crystalline and defect mechanisms of flow and fracture, and on to a consideration of major mechanical property tests and the basic metalworking process. It has been updated throughout, SI units have been added, and end-of-chapter study questions are included.

    Since the publication of the award-winning first edition of Evolutionary Psychology, there has been an explosion of research within the field. In this book, David M. Buss examines human behavior from an evolutionary perspective, providing students with the conceptual tools needed to study evolutionary psychology and apply them to empirical research on the human mind. This edition contains expanded coverage of cultural evolution, with a new section on culture–gene co-evolution, additional studies discussing interbreeding between modern humans and Neanderthals, expanded discussions of evolutionary hypotheses that have been empirically disconfirmed, and much more!

    It discusses neuroanatomy, cell and molecular mechanisms and signaling through a cognitive approach to behaviour. It features an expanded treatment of the nervous system, neurological and psychiatric diseases and perception.

    Integrated central case studies woven throughout each chapter, use real-life stories to give you a tangible and engaging framework around which to learn and understand the science behind environmental issues. Printed on FSC (Forest Stewardship Council) certified paper, the newly revised Fourth Edition engages you through the addition of new EnvisionIt photo essays.

    About The Author: Henry Gray, F.R.S., Fellow of the royal college of Surgeons: Lecturer on anatomy at St. George?s Hospital Medical School. Table Of Contents: Descriptive and Surgical Anatomy The Articulations Muscles and Fasclae The Blood-vascular system The Lymphatics The Nervous system The Organs of special sense The Organs of Digestion The Organs of voice and respiration The urinary organs The Male Organs of Generation The Female Organs of Generation The Surgical Anatomy of Hernia Surgical Anatomy of the Perinaeum General Anatomy or Histology Embryology

    Packed with full-color illustrations and case studies, this new edition offers a cutting-edge presentation of criminalistics and related laboratory subjects, including new chapters on forensic nursing and forensic entomology/botany. Written by highly respected experts, the book covers the very latest theories and practices in areas such as DNA testing, crime reconstruction, toxicology, chemistry of explosives and arson, and vehicle reconstruction. Also included are an instructor's manual and laboratory exercise manual.