Award-winning author Jonathan Edlow, M.D., shows the doctor as detective and the epidemiologist as elite sleuth in stories that are as gripping as the best thrillers.In these stories a notorious stomach bug turns a suburban dinner party into a disaster that almost claims its host; a diminutive woman routinely eats more than her football-playing boyfriend but continually loses weight; a young executive is diagnosed with lung cancer, yet the tumors seem to wax and wane inexplicably. Written for the lay person who wishes to better grasp how doctors decipher the myriad clues and puzzling symptoms they often encounter, each story presents a very different case where doctors must work to find the accurate diagnosis before it is too late. Edlow uses his unique ability to relate complex medical concepts in a writing style that is clear, engaging and easily understandable. The resulting stories both entertain us and teach us much about medicine, its history and the subtle interactions among pathogens, humans, and the environment.

    His great-grandfather was beaten to death by the Klu Klux Klan for attempting to vote. His grandfather was prevented from voting by Klan intimidation; his father was barred by poll taxes and literacy tests. Today, Cotton cannot vote because he, like many black men in the United States, has been labeled a felon and is currently on parole."As the United States celebrates the nation's "triumph over race" with the election of Barack Obama, the majority of young black men in major American cities are locked behind bars or have been labeled felons for life. Although Jim Crow laws have been wiped off the books, an astounding percentage of the African American community remains trapped in a subordinate status--much like their grandparents before them.In this incisive critique, former litigator-turned-legal-scholar Michelle Alexander provocatively argues that we have not ended racial caste in America: we have simply redesigned it. Alexander shows that, by targeting black men and decimating communities of color, the U.S. criminal justice system functions as a contemporary system of racial control, even as it formally adheres to the principle of color blindness. The New Jim Crow challenges the civil rights community--and all of us--to place mass incarceration at the forefront of a new movement for racial justice in America.

    Health disparities have remained stubbornly entrenched in the American health care system--and in Just Medicine Dayna Bowen Matthew finds that they principally arise from unconscious racial and ethnic biases held by physicians, institutional providers, and their patients.Implicit bias is the single most important determinant of health and health care disparities. Because we have missed this fact, the money we spend on training providers to become culturally competent, expanding wellness education programs and community health centers, and even expanding access to health insurance will have only a modest effect on reducing health disparities. We will continue to utterly fail in the effort to eradicate health disparities unless we enact strong, evidence-based legal remedies that accurately address implicit and unintentional forms of discrimination, to replace the weak, tepid, and largely irrelevant legal remedies currently available.Our continued failure to fashion an effective response that purges the effects of implicit bias from American health care, Matthew argues, is unjust and morally untenable. In this book, she unites medical, neuroscience, psychology, and sociology research on implicit bias and health disparities with her own expertise in civil rights and constitutional law. In a time when the health of the entire nation is at risk, it is essential to confront the issues keeping the health care system from providing equal treatment to all.

    This alarmed authorities, who feared certain "over-sexed" women could destroy civilization if allowed to reproduce and pass on their defects. Set against this backdrop, The Unfit Heiress chronicles the fight for inheritance, both genetic and monetary, between Ann Cooper Hewitt and her mother Maryon.In 1934, aided by a California eugenics law, the socialite Maryon Cooper Hewitt had her "promiscuous" daughter declared feebleminded and sterilized without her knowledge. She did this to deprive Ann of millions of dollars from her father's estate, which contained a child-bearing stipulation. When a sensational court case ensued, the American public was captivated. So were eugenicists, who saw an opportunity to restrict reproductive rights in America for decades to come.

    In the midst of all this death, a bizarre disease appeared in Europe. Eventually known as encephalitis lethargica, or sleeping sickness, it would spread across the world, leaving millions dead or locked in institutions. Then, in 1927, it would disappear as suddenly as it had arrived-or so the doctors at first thought. Asleep, set in 1920s and '30s New York, follows a group of neurologists through hospitals and insane asylums as they try to solve this worldwide epidemic. The symptoms could include not only unending sleep but dangerous insomnia, facial tics, catatonia, Parkinson's, and even violent insanity. Molly Caldwell Crosby, acclaimed author of The American Plague, explores the frightening history of this forgotten disease- and details the frantic effort to conquer it before it strikes again.

    In Four Lost Cities, acclaimed science journalist Annalee Newitz takes readers on an entertaining and mind-bending adventure into the deep history of urban life. Investigating across the centuries and around the world, Newitz explores the rise and fall of four ancient cities, each the center of a sophisticated civilization: the Neolithic site of Çatalhöyük in Central Turkey, the Roman vacation town of Pompeii on Italy’s southern coast, the medieval megacity of Angkor in Cambodia, and the indigenous metropolis Cahokia, which stood beside the Mississippi River where East St. Louis is today.Newitz travels to all four sites and investigates the cutting-edge research in archaeology, revealing the mix of environmental changes and political turmoil that doomed these ancient settlements. Tracing the early development of urban planning, Newitz also introduces us to the often anonymous workers—slaves, women, immigrants, and manual laborers—who built these cities and created monuments that lasted millennia.Four Lost Cities is a journey into the forgotten past, but, foreseeing a future in which the majority of people on Earth will be living in cities, it may also reveal something of our own fate.

    These three Great Untruths are part of a larger philosophy that sees young people as fragile creatures who must be protected and supervised by adults. But despite the good intentions of the adults who impart them, the Great Untruths are harming kids by teaching them the opposite of ancient wisdom and the opposite of modern psychological findings on grit, growth, and antifragility. The result is rising rates of depression and anxiety, along with endless stories of college campuses torn apart by moralistic divisions and mutual recriminations. This is a book about how we got here. First Amendment expert Greg Lukianoff and social psychologist Jonathan Haidt take us on a tour of the social trends stretching back to the 1980s that have produced the confusion and conflict on campus today, including the loss of unsupervised play time and the birth of social media, all during a time of rising political polarization. This is a book about how to fix the mess. The culture of “safety” and its intolerance of opposing viewpoints has left many young people anxious and unprepared for adult life, with devastating consequences for them, for their parents, for the companies that will soon hire them, and for a democracy that is already pushed to the brink of violence over its growing political divisions. Lukianoff and Haidt offer a comprehensive set of reforms that will strengthen young people and institutions, allowing us all to reap the benefits of diversity, including viewpoint diversity. This is a book for anyone who is confused by what’s happening on college campuses today, or has children, or is concerned about the growing inability of Americans to live and work and cooperate across party lines.

    In Missing Microbes, Dr. Martin Blaser invites us into the wilds of the human microbiome where for hundreds of thousands of years bacterial and human cells have existed in a peaceful symbiosis that is responsible for the health and equilibrium of our body. Now, this invisible eden is being irrevocably damaged by some of our most revered medical advances—antibiotics—threatening the extinction of our irreplaceable microbes with terrible health consequences. Taking us into both the lab and deep into the fields where these troubling effects can be witnessed firsthand, Blaser not only provides cutting edge evidence for the adverse effects of antibiotics, he tells us what we can do to avoid even more catastrophic health problems in the future. http://us.macmillan.com/missingmicrob...

    Democracy no longer ends with a bang--in a revolution or military coup--but with a whimper: the slow, steady weakening of critical institutions, such as the judiciary and the press, and the gradual erosion of long-standing political norms. The good news is that there are several exit ramps on the road to authoritarianism. The bad news is that, by electing Trump, we have already passed the first one.Drawing on decades of research and a wide range of historical and global examples, from 1930s Europe to contemporary Hungary, Turkey, and Venezuela, to the American South during Jim Crow, Levitsky and Ziblatt show how democracies die--and how ours can be saved.

    She began an investigative journey that took her to research labs, university food science departments, and factories around the country. What she discovered provides a rare, eye-opening, and sometimes disturbing, account of what we're really eating. Warner looks at how decades of food science have resulted in the cheapest, most abundant, most addictive, and most nutritionally inferior food in the world, and she uncovers startling evidence about the profound health implications of the packaged and fast foods that we eat on a daily basis.Combining meticulous research, vivid writing, and cultural analysis, Warner blows the lid off the largely undocumented, and lightly regulated, world of chemically treated and processed foods and lays bare the potential price we may pay for consuming even so-called healthy foods.

    It was inside, inside my head, where all had become so wretchedly different. I had the night before been incontrovertibly a man of stable mood, of calm, of good cheer and unforced bonhomie. Now I had become changed, with dreadful suddenness, into another being altogether.”Simon Winchester has never shied away from big, even enormous, topics—as evidenced by his bestselling biography of the Atlantic Ocean, his account of the Krakatoa volcanic eruption, and his wildly popular “The Professor and the Madman,” about the making of the Oxford English Dictionary. In his Byliner Original “The Man with the Electrified Brain,” he takes on arguably his most daunting subject yet: his own flirtation with madness, and one of nature’s greatest and most enduring mysteries, the human brain. As a geology student in his second year at Oxford, Winchester was known as a young man of even temper and keen intellect, until one June morning when he woke to find himself “changed with dreadful suddenness into another being altogether,” his normal life “slumped into chasm” and “folded in the dirt.” For a period of nine days, he lived in immobilizing fear. Everyday items—familiar paintings, a pile of books, his own robe hanging from a hook—became objects of horror; the world lost color, purpose, all sense and safety. When the episode finally passed, he returned to normal, presuming that what had happened to him was a fluke. It wasn’t. The episode repeated itself at unpredictable and dangerous intervals for four years—always lasting for nine days—and very nearly caused the author’s death while he was on an expedition in the Arctic. What was wrong with him? Where could he find help? Would he spend the rest of his life anticipating the return of these mental blackouts? With the urgency of a whodunit, Winchester describes the coming and going of these terrifying dissociative states and the chance encounter that led to the controversial treatment of electroconvulsive therapy, which may or may not have cured him once and for all. Written by a consummate storyteller, “The Man with the Electrified Brain” locates that finest of lines between sanity and insanity and is Winchester’s most riveting and deeply personal work yet.

    Among the most compelling and perplexing of these symptoms are the strange visual hallucinations and distortions of space, time, and body image which migraineurs sometimes experience. Portrayals of these uncanny states have found their way into many works of art, from the heavenly visions of Hildegard von Bingen to Alice in Wonderland. Dr. Oliver Sacks argues that migraine cannot be understood simply as an illness, but must be viewed as a complex condition with a unique role to play in each individual's life.

    But in Catching Fire, renowned primatologist Richard Wrangham presents a startling alternative: our evolutionary success is the result of cooking. In a groundbreaking theory of our origins, Wrangham shows that the shift from raw to cooked foods was the key factor in human evolution. when our ancestors adapted to using fire, humanity began.Once our hominid ancestors began cooking their food, the human digestive tract shrank and the brain grew. Time once spent chewing tough raw food could be used instead to hunt and to tend camp. Cooking became the basis for pair bonding and marriage, created the household, and even led to a sexual division of labor.Tracing the contemporary implications of our ancestors' diets, Catching Fire sheds new light on how we came to be the social, intelligent, and sexual species we are today. A pathbreaking new theory of human evolution, Catching Fire will provoke controversy and fascinate anyone interested in our ancient origins--or in our modern eating habits.--from the dustjacket

    Stamped from the Beginning uses the lives of five major American intellectuals to offer a window into the contentious debates between assimilationists and segregationists and between racists and anti-racists. From Puritan minister Cotton Mather to Thomas Jefferson, from fiery abolitionist William Lloyd Garrison to brilliant scholar W. E. B. Du Bois to legendary anti–prison activist Angela Davis, Kendi shows how and why some of our leading pro-slavery and pro–civil rights thinkers have challenged or helped cement racist ideas in America.As Kendi illustrates, racist thinking did not arise from ignorance or hatred. Racist ideas were created and popularized in an effort to defend deeply entrenched discriminatory policies and to rationalize the nation’s racial inequities in everything from wealth to health. While racist ideas are easily produced and easily consumed, they can also be discredited. In shedding much–needed light on the murky history of racist ideas, Stamped from the Beginning offers tools to expose them—and in the process, reason to hope.