Growing understanding of the immune system, and especially the creation of immune memory (long lasting protection), which can be harnessed in the design of vaccines, have been major breakthroughs in medicine.In this Very Short Introduction, Paul Klenerman describes the immune system, and how it works in health and disease. In particular he focuses on the human immune system, considering how it evolved, the basic rules that govern its behavior, and the major health threats where it is important. Theimmune system comprises a series of organs, cells and chemical messengers which work together as a team to provide defence against infection. Klenerman discusses these components, the critical signals that trigger them and how they exert their protective effects, including so-called innate immuneresponses, which react very fast to infection, and adaptive immune responses, which have huge diversity and a capacity to recognize and defend against a massive array of micro-organisms. Klenerman also considers what happens when our immune systems fail to be activated effectively, leading toserious infections, problems with inherited diseases, and also HIV/AIDS. At the opposite extreme, as Klenerman shows, an over-exaggerated immune response leads to inflammatory diseases such as Multiple Sclerosis and Rheumatoid Arthritis, as well as allergy and asthma. Finally he looks at the Immunesystem v2.o - how immune therapies and vaccines can be advanced to protect us against the major diseases of the 21st century.ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, andenthusiasm to make interesting and challenging topics highly readable.

    It traces the history and cultural impact of the elements on humankind, and examines why people have long sought to identify thesubstances around them. The book includes chapters on particular elements such as gold, iron, and oxygen, showing how they shaped culture and technology. Looking beyond the Periodic Table, the author examines our relationship with matter, from the uncomplicated vision of the Greek philosophers, whobelieved there were four elements--earth, air, fire, and water--to the work of modern-day scientists in creating elements such as hassium and meitnerium. Packed with anecdotes, The Elements is a highly engaging and entertaining exploration of the fundamental question: what is the world made from?

    Arguments still rage about the implications of his evolutionary theory, and scepticism about the value of Darwin's contribution to knowledge is widespread. In this analysis of Darwin's major insights and arguments, Jonathan Howard reasserts the importance of Darwin's work for the development of modern science and culture."--BOOK JACKET.

    Years before synchronized sound became the norm, projected moving images were shown to musical accompaniment, whether performed by a lone piano player or a hundred-piece orchestra. Today film music has become its own industry, indispensable to the marketability of movies around the world.Film Music: A Very Short Introduction is a compact, lucid, and thoroughly engaging overview written by one of the leading authorities on the subject. After opening with a fascinating analysis of the music from a key sequence in Quentin Tarantino's Reservoir Dogs, Kathryn Kalinak introduces readers not only to important composers and musical styles but also to modern theoretical concepts about how and why film music works. Throughout the book she embraces a global perspective, examining film music in Asia and the Middle East as well as in Europe and the United States. Key collaborations between directors and composers--Alfred Hitchcock and Bernard Herrmann, Akira Kurosawa and Fumio Hayasaka, Federico Fellini and Nino Rota, to name only a few--come under scrutiny, as do the oft-neglected practices of the silent film era. She also explores differences between original film scores and compilation soundtracks that cull music from pre-existing sources.

    During that time, it has spread among the neighboring peoples - the Mongol, Himalayan, and Siberian peoples, Manchus and Chinese. At its height is has been practiced in regions as far west as the Volga river and to the east in Beijing. Its capacity for creative adaptation is demonstrated by its recent growth in Europe and America. At the same time, it is at the center of political contestation in ethnically Tibetan regions of China, while its best known exponent, the Dalai Lama, has become one of the most admired religious leaders in the world today. But what does this religion teach? Just what is the position of the Dalai Lama, and how will his succession be assured? Is it true that Tibetan Buddhism in entirely suppressed in China? Scholar Matthew Kapstein offers a brief account responding to these questions and more in this Very Short Introduction, in terms that are accessible to students, general readers, journalists, and others who are curious to learn the most essential features of Tibetan Buddhist history, teachings, and practice. About the Series: Oxford's Very Short Introductions series offers concise and original introductions to a wide range of subjects--from Islam to Sociology, Politics to Classics, Literary Theory to History, and Archaeology to the Bible. Not simply a textbook of definitions, each volume in this series provides trenchant and provocative--yet always balanced and complete--discussions of the central issues in a given discipline or field. Every Very Short Introduction gives a readable evolution of the subject in question, demonstrating how the subject has developed and how it has influenced society. Eventually, the series will encompass every major academic discipline, offering all students an accessible and abundant reference library. Whatever the area of study that one deems important or appealing, whatever the topic that fascinates the general reader, the Very Short Introductions series has a handy and affordable guide that will likely prove indispensable.

    While pure mathematics is mostly interested in abstract structures, applied mathematics sits at the interface between this abstract world and the world inwhich we live. This area of mathematics takes its nourishment from society and science and, in turn, provides a unified way to understand problems arising in diverse fields.This Very Short Introduction presents a compact yet comprehensive view of the field of applied mathematics, and explores its relationships with (pure) mathematics, science, and engineering. Explaining the nature of applied mathematics, Alain Goriely discusses its early achievements in physics andengineering, and its development as a separate field after World War II. Using historical examples, current applications, and challenges, Goriely illustrates the particular role that mathematics plays in the modern sciences today and its far-reaching potential.ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, andenthusiasm to make interesting and challenging topics highly readable.

    Yet there is much more to the debate than theclash of these extremes. As Thomas Dixon shows in this balanced and thought-provoking introduction, a whole range of views, subtle arguments, and fascinating perspectives can be found on this complex and centuries-old subject. He explores the key philosophical questions that underlie the debate, but also highlights the social, political, and ethical contexts that have made the tensions between science and religion such a fraught and interesting topic in the modern world. Dixon emphasizes how the modern conflict between evolution and creationism is quintessentially an American phenomenon, arising from the culture and history of the United States, as exemplified through the ongoing debates about how to interpret the First-Amendment's separation of church and state. Along the way, he examines landmark historical episodes such as the Galileo affair, Charles Darwin's own religious andscientific odyssey, the Scopes Monkey Trial in Tennessee in 1925, and the Dover Area School Board case of 2005, and includes perspectives from non-Christian religions and examples from across the physical, biological, and social sciences.About the Series: Combining authority with wit, accessibility, and style, Very Short Introductions offer an introduction to some of life's most interesting topics. Written by experts for the newcomer, they demonstrate the finest contemporary thinking about the central problems and issues in hundredsof key topics, from philosophy to Freud, quantum theory to Islam.

    It requires, in short, an understanding of probability. In this Very Short Introduction, John Haigh introduces the ideas of probability--and the different philosophical approaches to probability--and gives a brief account of the history of development of probability theory, from Galileo and Pascal to Bayes, Laplace, Poisson, and Markov. He describes the basic probability distributions and discusses a wide range of applications in science, economics, and a variety of other contexts such as games and betting. He concludes with an intriguing discussion of coincidences and some curious paradoxes.

    Global climate change, shifting global cycles of the weather, widespread pollution, radioactive fallout, plastic accumulation, species invasions, the mass extinction of species - these are just some of the many indicators that we will leave a lasting record in rock, the scientific basis for recognizing new time intervals in Earth's history. The "Anthropocene," as the proposed new epoch has been named, is regularly in the news.Even with such robust evidence, the proposal to formally recognize our current time as the Anthropocene remains controversial both inside and outside the scholarly world, kindling intense debates. The reason is clear. The Anthropocene represents far more than just another interval of geologic time. Instead, the Anthropocene has emerged as a powerful new narrative, a concept through which age-old questions about the meaning of nature and even the nature of humanity are being revisited and radically revised.This Very Short Introduction explains the science behind the Anthropocene and the many proposals about when to mark its beginning: The nuclear tests of the 1950s? The beginnings of agriculture? The origins of humans as a species? Erle Ellis considers the many ways that the Anthropocene's "evolving paradigm" is reshaping the sciences, stimulating the humanities, and foregrounding the politics of life on a planet transformed by humans. The Anthropocene remains a work in progress. Is this the story of an unprecedented planetary disaster? Or of newfound wisdom and redemption? Ellis offers an insightful discussion of our role in shaping the planet, and how this will influence our future on many fronts.ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

    It enables us to understand the structure and evolution of planetary systems, stars, galaxies, interstellar gas, and the cosmos as a whole.In this Very Short Introduction, the leading astrophysicist James Binney shows how the field of astrophysics has expanded rapidly in the past century, with vast quantities of data gathered by telescopes exploiting all parts of the electromagnetic spectrum, combined with the rapid advance of computing power, which has allowed increasingly effective mathematical modelling. He illustrates how the application of fundamental principles of physics - the consideration of energy and mass, and momentum - and the two pillars of relativity and quantum mechanics, has provided insights into phenomena ranging from rapidly spinning millisecond pulsars to the collision of giant spiral galaxies. This is a clear, rigorous introduction to astrophysics for those keen to cut their teeth on a conceptual treatment involving some mathematics.ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable

    As of 2004 an estimated 40 million people were living with the disease, and about 20 million had died. Despite rapid scientific advances there is still no cure and the drugs are expensive and toxic. In the developing world, especially in parts of Africa, life expectancy has plummeted to below 35 years, causing a serious decline in economic growth, a sharp increase in orphans, and the imminent collapse of health care systems. The news is not all bleak though. There have been unprecedented breakthroughs in understanding diseases and developing drugs. Because the disease is so closely linked to sexual activity and drug use, the need to understand and change behavior has caused us to reassess what it means to be human and how we should operate in the globalizing world. This Very Short Introduction tackles the science, the international and local politics, the fascinating demographics, and the devastating consequences of the disease, and suggests how we must respond.About the Series: Oxford's Very Short Introductions offers concise and original introductions to a wide range of subjects--from Islam to Sociology, Politics to Classics, and Literary Theory to History. Not simply a textbook of definitions, each volume provides trenchant and provocative--yet always balanced and complete--discussions of the central issues in a given topic. Every Very Short Introduction gives a readable evolution of the subject in question, demonstrating how it has developed and influenced society. Whatever the area of study, whatever the topic that fascinates the reader, the series has a handy and affordable guide that will likely prove indispensable.

    However, their impact has not been limited to debates about geology and evolution: attempts to explain their existence has shaken religion at its very roots, and they have remained a subject of ceaseless fascination for people of all ages and backgrounds. In this readable and wide-ranging book, Keith Thomson provides a remarkably all-encompassing explanation of fossils as a phenomenon. How did Darwin use fossils to support his theory of evolution? What are living fossils? What fossils will we leave behind for future generations to examine? Beyond the scientific aspects, Thomson highlights the impact of fossils on philosophy and mythology, our concept of time, and today's popular culture. From the black market to the Piltdown Man, and from mythological dragons to living dinosaurs, fossils hold a permanent place in the popular imagination.

    The book discusses environmental issues including pollution control, reducing environmental damage, global climate change policies, questions about how we should balance environmental and economic considerations, and what form government policies should take. In recent years, Smith reveals, many economists have argued for greater use of incentives such as pollution charges and emissions trading rather than more traditional direct regulation of polluters. Including many illustrative case studies, this book offers an illuminating introduction to an exciting field of economics.About the Series: Combining authority with wit, accessibility, and style, Very Short Introductions offer an introduction to some of life's most interesting topics. Written by experts for the newcomer, they demonstrate the finest contemporary thinking about the central problems and issues in hundreds of key topics, from philosophy to Freud, quantum theory to Islam.

    In an age where we've mapped the human genome and explored much of the physical world, the study of people's behaviour is one of the most exciting frontiers of scientific endeavor.In this Very Short Introduction Richard Crisp tells the story of social psychology, its history, concepts and major theories. Discussing the classic studies that have defined the discipline, Crisp introduces social psychology's key thinkers, and shows how their personal histories spurred them to understand what connects people to people, and the societies in which we live. Taking us from the first ideas of the discipline to its most cutting edge developments, Crisp demonstrates how social psychology remains profoundly relevant to everyday life. From attitudes to attraction, prejudice to persuasion, health to happiness - social psychology provides insights that can change the world, and help us tackle the defining problems of the 21st century.ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

    Looking at texts ranging from the Gospels from NagHammadi to the Dialogues with the Risen Savior, Paul Foster shows how the apocryphal gospels reflect the diversity that existed within early Christianity, and considers the extent to which they can be used to reconstruct an accurate portrait of the historical Jesus. Foster demonstrates how closeanalysis of text, contents, and context are vital in assessing the value and authenticity of such ancient documents. Including discussions of controversies and case-studies such as the alleged hoax surrounding the discovery of Secret Mark, Foster concludes that the non-canonical texts, considered inthe correct context, can help us reach a more complete understanding of the multi-faceted nature of early Christianity.About the Series: Combining authority with wit, accessibility, and style, Very Short Introductions offer an introduction to some of life's most interesting topics. Written by experts for the newcomer, they demonstrate the finest contemporary thinking about the central problems and issues in hundredsof key topics, from philosophy to Freud, quantum theory to Islam.