In 1919, Spanish flu killed over 50 million people, more than died in both world wars combined. In 1950, an estimated 50 million people caught smallpox worldwide, of whom 10 million died. In 1980, before measles vaccine was widely used, an estimated 2.6 million children died of measles every year. Today we are hostage to a new pandemic disease -the seemingly unstoppable COVID-19.Less than 100 years ago, losing a child to an infection like diphtheria or polio was a dreaded but almost inevitable sorrow faced by all parents, from the richest to the poorest. Today, these killer diseases are almost never seen in industrialised countries, thanks to the development of vaccines. Immunisation has given modern parents peace of mind their ancestors could not imagine.The history of vaccination is rich with trial, error, sabotage and success. It encompasses the tragedy of lives lost, the drama of competition and discovery, the culpability of botched testing, and the triumph of effective, lifelong immunity. Yet with the eradication in the first world of some of humanity's deadliest foes, complacency in some quarters has set in. COVID-19 has us again racing for a vaccine. The story of past achievements and failures helps us keep the race - and the hope - in perspective.This is a book for everyone who wants to understand our past - and cares about our future.PRAISE'Anyone who has doubts about the life-saving miracle of vaccination should read this' Steven Carroll, Sydney Morning Herald'An entertaining and engaging work that is sure to delight general readers' Australian Book Review'The ideal handbook for pregnant women, parents, travellers, childcare and aged-care workers, GPs and anyone with an interest in public health' The Australian'Isaacs explores the understanding of immunity as it develops from the fifth century BC to the present day and thrills us with the progressive successes of each of the 14 vaccines which a child routinely receives today ... The work is authoritative, beguiling, amusing, instructive and inspirational. It deserves a wide readership, including infectious disease experts, other health professionals and, most assuredly, a diversity of lay people' Sir Gustav Nossal, immunologist and director of The Walter and Eliza Institute of Medical Research, Melbourne, 1965-1996'A rollicking story of human endeavour, error, misinformation, success and failure ... and more than a glimpse of why we need to continue to research, evaluate, educate and fund vaccines to prevent disease' Fiona Stanley, Distinguished Research Professor, University of Western Australia'Effortlessly accessible, Defeating the Ministers of Death brilliantly reveals the people behind the most important public health intervention in history' Professor Andrew J Pollard, Department of Paediatrics, University of Oxford'This book is an unflinching look at the triumphs and inevitable tragedies in the war against infectious diseases. Nonfiction is at its best when it reads like fiction. And David Isaacs has written a page turner' Paul A. Offit, MD, author of Bad Advice: Or Why Celebrities, Politicians, and Activists Aren't Your Best Source of Health Information

    a remarkable story—Leeza Gibbons, NBC-TV • Grippingly told ... a wonderful, powerful book—David Berner, Radio CKNW Vancouver • Reads with the pace of a taut thriller—George Henderson, Gloucestershire Citizen • Mesmerizing—Bob Stall, Vancouver Province. Now revised and updated. The amazing, true story of how medical authorities allow a family doctor to continue practising even after he begins living with a 15-year-old patient—and allegedly has sex with another girl in exchange for giving drugs to her father. The notorious doctor still carries on as before and a third patient complains about infamous conduct—until he silences her by putting out a contract for murder.

    Conley, the first female tenured professor of neurosurgery in the country, made headline news when she resigned from Stanford University to protest the medical school's unabashed gender discrimination. In this controversial, forthright memoir, Conley portrays the world of academic medicine in which women are still considered inferior; she also explains why, as a consequence, the research and treatment of women's health problems lag far behind those of men. In assessing why women's careers and psyches are suffering, Conley provides a first-person look into what it is like to be an accomplished woman within this restrictive medical world, offering invaluable advice to patients and future doctors alike.

    The chafing restrictions of a typical upbringing in upper-class, small town Alabama simply did not apply to Zelda, who was described as an unusual child and permitted to roam the streets with little supervision. Zelda refused to blossom into a typical 'Southern belle' on anyone's terms but her own and while still in high school enjoyed the status of a local celebrity for her shocking behavior. Everybody in town knew the name Zelda Sayre. Queen of the Montgomery social scene, Zelda had a different beau ready and willing to show her a good time for every day of the week. Before meeting F. Scott Fitzgerald, Zelda's life was a constant pursuit of pleasure. With little thought for the future and no responsibilities to speak of, Zelda committed herself fully to the mantra that accompanied her photo in her high school graduation book: "Why should all life be work, when we all can borrow. Let's think only of today, and not worry about tomorrow." But for now Zelda was still in rehearsal for her real life to begin, a life she was sure would be absolutely extraordinary. Zelda Sayre married F. Scott Fitzgerald on the 3rd of April 1920 and left sleepy Montgomery behind in order to dive headfirst into the shimmering, glamourous life of a New York socialite. With the publication of Scott's first novel, This Side of Paradise, Zelda found herself thrust into the limelight as the very epitome of the Flapper lifestyle. Concerned chiefly with fashion, wild parties and flouting social expectations, Zelda and Scott became icons of the Jazz Age, the personification of beauty and success. What Zelda and Scott shared was a romantic sense of self-importance that assured them that their life of carefree leisure and excess was the only life really worth living. Deeply in love, the Fitzgeralds were like to sides of the same coin, each reflecting the very best and worst of each other. While the world fell in love with the image of the Fitzgeralds they saw on the cover of magazines, behind the scenes the Fitzgerald's marriage could not withstand the tension of their creative arrangement. Zelda was Scott's muse and he mercilessly mined the events of their life for material for his books. Scott claimed Zelda's memories, things she said, experiences she had and even passages from her diary as his possessions and used them to form the basis of his fictional works. Zelda had a child but the domestic sphere offered no comfort or purpose for her. The Flapper lifestyle was not simply a phase she lived through, it formed the very basis of her character and once the parties grew dull, the Fitzgeralds' drinking became destructive and Zelda's beauty began to fade, the world held little allure for her. Zelda sought reprieve in work and tried to build a career as a ballet dancer. When that didn't work out she turned to writing but was forbidden by Scott from using her own life as material. Convinced that she would never leave her mark on the world as deeply or expressively as Scott had, Zelda retreated into herself and withdrew from the people she knew in happier times. The later years of Zelda's life were marred by her detachment from reality as, diagnosed with schizophrenia, Zelda spent the last eighteen years of her life living in and out of psychiatric hospitals. As Scott's life unraveled due to alcohol abuse, Zelda looked back on the years they had spent together, young and wild and beautiful, as the best of her life. She may have been right but she was wrong about one thing, Zelda did leave her mark on the world and it was a deep and expressive mark that no one could have left but her. Zelda Fitzgerald: The Biography

    The most trusted sources in the auto industry have called its Model S the most advanced, safest and best-performing car ever built - and it doesn’t use a drop of gasoline. Tesla has changed the way the public perceives electric vehicles, and inspired the major automakers to revive their own dormant efforts to sell EVs. However, even amidst the avalanche of media coverage that followed the triumph of the Model S, few have grasped the true significance of what is happening. Tesla has redefined the automobile, sparked a new wave of innovation comparable to the internet and mobile computing revolutions, and unleashed forces that will transform not just the auto industry, but every aspect of society. The Tesla story is one part of an ongoing tide of change driven by the use of information technology to eliminate “friction” such as geographic distance, middlemen and outdated regulations. Tesla is simply applying the new order to the auto industry, but the automobile is such a pervasive influence in our lives that redefining how it is designed, built, driven and sold will have sweeping effects in unexpected areas. Just as Tesla built the Model S as an electric vehicle “from the ground up,” it has taken an outsider’s approach to the way it markets its cars. Its direct sales model has drawn legal challenges from entrenched auto dealers, who fear that their outdated business model will be destroyed. Its systems approach to the software and electronics in its cars has highlighted how far behind the technological times the major automakers are. It’s easy to see why readers find Tesla irresistible. CEO Elon Musk is a superstar entrepreneur, a “nauseatingly pro-US” immigrant and the leader of two other cutting-edge companies. Tesla dares to challenge the establishment behemoths and, so far at least, has handily beaten them at their own game. In this history of the 21st century’s most exciting startup, Charles Morris begins with a brief history of EVs and a biography of Tesla’s driving force, Elon Musk. He then details the history of the company, told in the words of the Silicon Valley entrepreneurs who made it happen. There are many fascinating stories here: Martin Eberhard’s realization that there were many like himself, who loved fast cars but wanted to help the environment and bring about the post-oil age; the freewheeling first days, reminiscent of the early internet era; the incredible ingenuity of the team who built the Roadster; Tesla’s near-death experience and miraculous resurrection; the spiteful split between the company’s larger-than-life leaders; the gloves-off battles with hostile media such as Top Gear and the New York Times; and the media’s ironic about-face when the magnificent Model S won the industry’s highest honors, and naysayers became cheerleaders overnight. And the story is just beginning: Tesla has breathtakingly ambitious plans for the future.This book was updated May 1, 2015 to include the latest on the Gigafactory and the D package.

    In 1905 an unknown 26-year-old clerk at the Swiss Patent Office, who had supposedly failed math in school, burst on to the scientific scene and swept away the hidebound theories of the day. The clerk, Albert Einstein, introduced a new and unexpected understanding of the universe and launched the two great revolutions of twentieth-century physics, relativity and quantum mechanics. The obscure origin and wide-ranging brilliance of the work recalled Isaac Newton’s “annus mirabilis” (miracle year) of 1666, when as a 23-year-old seeking safety at his family manor from an outbreak of the plague, he invented calculus and laid the foundations for his theory of gravity. Like Newton, Einstein quickly became a scientific icon--the image of genius and, according to Time magazine, the Person of the Century.The actual story is much more interesting. Einstein himself once remarked that “science as something coming into being ... is just as subjectively, psychologically conditioned as are all other human endeavors.” In this profile, the historian of science L. Randles Lagerstrom takes you behind the myth and into the very human life of the young Einstein. From family rifts and girlfriend troubles to financial hardships and jobless anxieties, Einstein’s early years were typical of many young persons. And yet in the midst of it all, he also saw his way through to profound scientific insights. Drawing upon correspondence from Einstein, his family, and his friends, Lagerstrom brings to life the young Einstein and enables the reader to come away with a fuller and more appreciative understanding of Einstein the person and the origins of his revolutionary ideas.About the cover image: While walking to work six days a week as a patent clerk in Bern, Switzerland, Einstein would pass by the famous "Zytglogge" tower and its astronomical clocks. The daily juxtaposition was fitting, as the relative nature of time and clock synchronization would be one of his revolutionary discoveries in the miracle year of 1905.

    No human being who stood on her decks that fateful night was alive to commemorate the event on its 100th anniversary. Their stories are with us, however, and the lessons remain. From the moment the world learned the Titanic had sunk, we wanted to know, who had survived? Those answers didn’t come until the evening of Thursday, April 18, 1912―when the Cunard liner Carpathia finally reached New York with the 706 survivors who had been recovered from Titanic’s lifeboats. Harold Bride, “Titanic’s surviving wireless operator,” relayed the story of the ship’s band. “The way the band kept playing was a noble thing. I heard it first while still we were working wireless when there was a ragtime tune for us. The last I saw of the band, when I was floating out in the sea with my lifebelt on, it was still on deck playing ‘Autumn.’ How they ever did it I cannot imagine.” There were stories of heroism―such as that of Edith Evans, who was waiting to board collapsible Lifeboat D, the last boat to leave Titanic, when she turned to Caroline Brown and said, “You go first. You have children waiting at home.” The sacrifice cost Evans her life, but as Mrs. Brown said later, “It was a heroic sacrifice, and as long as I live I shall hold her memory dear as my preserver, who preferred to die so that I might live.” There was mystery. There was bravery. There was suspense. There was cowardice. Most men who survived found themselves trying to explain how they survived when women and children had died. But mostly, there was loss. On her return to New York after picking up Titanic’s survivors, Carpathia had become known as a ship of widows. Rene Harris, who lost her husband, Broadway producer Henry Harris, in the disaster, later spoke of her loss when she said, “It was not a night to remember. It was a night to forget.” Drawing on a wealth of previously unpublished letters, memoirs, and diaries as well as interviews with survivors and family members, veteran author and writer Alan Rockwell brings to life the colorful voices and the harrowing experiences of many of those who lived to tell their story. More than 100 years after the RMS Titanic met its fatal end, the story of the tragic wreck continues to fascinate people worldwide. Though many survivors and their family members disappeared into obscurity or were hesitant to talk about what they went through, others were willing to share their experiences during the wreck and in its aftermath. This book recounts many of these first-hand accounts in graphic, compelling detail.

    And their fans had ulcers. Now, veteran sports columnist Terry Pluto explains why everything kept going wrong. This detailed report on two decades of disappointment takes a behind-the-scenes look at upheaval in the front office, frustration on the field, and headaches and heartache in the stands. His earlier book False Start: How the New Browns Were Set Up to Fail told how the NFL hamstrung the new franchise. Who could have predicted the limping would last 19 years? This book picks up the story. Season after season began with hope in spring for the NFL draft (“the Browns’ version of the Super Bowl,” a fan called it) . . . often a new coach or GM or quarterback (or all three) . . . then the losses . . . and back to rebuilding. Pluto reviews all the major moves—draft choices and deals, hiring and firing and reshuffling—and the results. If you’re a Browns fan who wants to understand what went wrong with your team, this is the place to start. Includes heartfelt and humorous opinions contributed by fans.

    Donovan Gray answers that question in Dude, Where's My Stethoscope? - a laugh-out-loud funny, heartbreaking and sometimes poignant collection of true-life medical short stories. We follow Dr. Gray through medical school and two decades of unforgettable ER and family practice. Humorously written in an engaging mash-up of formal prose and informal medical slang with a nod to pop culture and ancient mythology, Dude is a powerful book that captures the essence of what it is to be an emergency room doctor.

    The dos and don'ts of travelling and staying in Iceland. Five chapters with multiple tips in each one explain what is expected of you as a traveller - as well as some bonus tips on what you can do.

    Born in 1908, in The Patch, Chicago, Giancana joined the Forty-Two gang of lawless juvenile punks in 1921 and quickly proved himself as a skilled 'wheel man' (or getaway driver), extortionist and vicious killer. Called up to the ranks of the Outfit, he reputedly held talks with the CIA about assassinating Fidel Castro, shared a girlfriend with John F. Kennedy and had friends in high places, including Sammy Davis Jr., Frank Sinatra, Shirley MacLaine, Marilyn Monroe and, some say, the Kennedys, although he fell out with them.The story of Sam Giancana will overturn many of your beliefs about America during the Kennedy era. If you want to know Giancana's role in the brother's deaths, and more of the intrigue surrounding that of Marilyn Monroe, this book will fill you in on the murky lives of many shady characters who really ruled the day, both in Chicago and elsewhere.

    

    

    It is the story of two nurses who witnessed the early years of the HIV/AIDS epidemic from the frontline. It focuses on their lives and their experiences. Some of the story is raw, sometimes graphic, but familiar for people with HIV infection, family members, friends, and other nurses and medical professionals such as Ellen and Valery. There were hundreds of nurses who went through what Ellen and Valery experienced. They want to tell this story to give a voice to a generation lost, encouraging the world to remember one simple thing: this history cannot be repeated.