A killer with little respect for class or wealth, cholera ravaged the squalid streets of Soho and rocked the great centers of Victorian power. In this gripping book, Sandra Hempel tells the story of John Snow, a reclusive doctor without money or social position, who—alone and unrecognized—had the genius to look beyond the conventional wisdom of his day and uncover the truth behind the pandemic. She describes how Snow discovered that cholera was spread through drinking water and how this subsequently laid the foundations for the modern, scientific investigation of today's fatal plagues. A dramatic account with a colorful cast of characters, The Strange Case of the Broad Street Pump features diversions into fascinating facets of medical and social history, such as Snow's tending of Queen Victoria in childbirth, Dutch microbiologist Leeuwenhoek's deliberate breeding of lice in his socks, Dickensian children's farms, and riotous nineteenth-century anesthesia parties. An afterword discusses the new threat of infectious diseases—including malaria, yellow fever, and cholera—with today's global warming. Copub: Granta

    is the first deep-dive investigation of a hazardous and illicit industry that has created a worldwide epidemic, ravaging communities and overwhelming and confounding government agencies that are challenged to combat it. "A whole new crop of chemicals is radically changing the recreational drug landscape," writes Ben Westhoff. "These are known as Novel Psychoactive Substances (NPS) and they include replacements for known drugs like heroin, cocaine, ecstasy, and marijuana. They are synthetic, made in a laboratory, and are much more potent than traditional drugs"--and all-too-often tragically lethal. Drugs like fentanyl, K2, and Spice--and those with arcane acronyms like 25i-NBOMe-- were all originally conceived in legitimate laboratories for proper scientific and medicinal purposes. Their formulas were then hijacked and manufactured by rogue chemists, largely in China, who change their molecular structures to stay ahead of the law, making the drugs' effects impossible to predict. Westhoff has infiltrated this shadowy world, becoming the first journalist to report from inside an illicit Chinese fentanyls lab and providing startling and original reporting on how China's vast chemical industry operates, and how the Chinese government subsidizes it. He tracks down the little-known scientists who invented these drugs and inadvertently killed thousands, as well as a mysterious drug baron who turned the law upside down in his home country of New Zealand. Poignantly, Westhoff chronicles the lives of addicted users and dealers, families of victims, law enforcement officers, and underground drug awareness organizers in the U.S. and Europe. Together they represent the shocking and riveting full anatomy of a calamity we are just beginning to understand. From its depths, as Westhoff relates, are emerging new strategies that may provide essential long-term solutions to the drug crisis that has affected so many.

    Half of all species could disappear by the end of the century, and scientists now concede that most of America’s endangered animals will survive only if conservationists keep rigging the world around them in their favor. So Mooallem ventures into the field, often taking his daughter with him, to move beyond childlike fascination and make those creatures feel more real. Wild Ones is a tour through our environmental moment and the eccentric cultural history of people and wild animals in America that inflects it—from Thomas Jefferson’s celebrations of early abundance to the turn-of the-last-century origins of the teddy bear to the whale-loving hippies of the 1970s. In America, Wild Ones discovers, wildlife has always inhabited the terrain of our imagination as much as the actual land.The journey is framed by the stories of three modern-day endangered species: the polar bear, victimized by climate change and ogled by tourists outside a remote northern town; the little-known Lange’s metalmark butterfly, foundering on a shred of industrialized land near San Francisco; and the whooping crane as it’s led on a months-long migration by costumed men in ultralight airplanes. The wilderness that Wild Ones navigates is a scrappy, disorderly place where amateur conservationists do grueling, sometimes preposterous-looking work; where a marketer maneuvers to control the polar bear’s image while Martha Stewart turns up to film those beasts for her show on the Hallmark Channel. Our most comforting ideas about nature unravel. In their place, Mooallem forges a new and affirming vision of the human animal and the wild ones as kindred creatures on an imperfect planet.With propulsive curiosity and searing wit, and without the easy moralizing and nature worship of environmental journalism’s older guard, Wild Ones merges reportage, science, and history into a humane and endearing meditation on what it means to live in, and bring a life into, a broken world.

    Their numbers are in freefall, dropping by nearly 70 percent in the last sixty years, a billion fewer now than in 1950. Extinction stalks the ocean, and there is a danger that the hundred-million-year-old cries of a seabird colony, rolling around in the bays and headlands of high latitudes, will this century become but a memory.

    In The Poisoner's Handbook Blum draws from highly original research to track the fascinating, perilous days when a pair of forensic scientists began their trailblazing chemical detective work, fighting to end an era when untraceable poisons offered an easy path to the perfect crime. Drama unfolds case by case as the heroes of The Poisoner's Handbook—chief medical examiner Charles Norris and toxicologist Alexander Gettler—investigate a family mysteriously stricken bald, Barnum and Bailey's Famous Blue Man, factory workers with crumbling bones, a diner serving poisoned pies, and many others. Each case presents a deadly new puzzle and Norris and Gettler work with a creativity that rivals that of the most imaginative murderer, creating revolutionary experiments to tease out even the wiliest compounds from human tissue. Yet in the tricky game of toxins, even science can't always be trusted, as proven when one of Gettler's experiments erroneously sets free a suburban housewife later nicknamed "America's Lucretia Borgia" to continue her nefarious work. From the vantage of Norris and Gettler's laboratory in the infamous Bellevue Hospital it becomes clear that killers aren't the only toxic threat to New Yorkers. Modern life has created a kind of poison playground, and danger lurks around every corner. Automobiles choke the city streets with carbon monoxide; potent compounds, such as morphine, can be found on store shelves in products ranging from pesticides to cosmetics. Prohibition incites a chemist's war between bootleggers and government chemists while in Gotham's crowded speakeasies each round of cocktails becomes a game of Russian roulette. Norris and Gettler triumph over seemingly unbeatable odds to become the pioneers of forensic chemistry and the gatekeepers of justice during a remarkably deadly time. A beguiling concoction that is equal parts true crime, twentieth-century history, and science thriller, The Poisoner's Handbook is a page-turning account of a forgotten New York.

    This is science at its best, the art of understanding truth and beauty' - Chris Packham'Enchanting and exhilarating ... Where the Animals Go is an eye-opening exercise in perspective that puts place and space at the heart of the 21st-century conservation debate' - Literary ReviewFrom the best-selling authors of London: The Information Capital comes the first book to use big data to map the movements and behaviour of wild animals all over the worldFor thousands of years, tracking animals meant following footprints. Now satellites, drones, camera traps, cellphone networks, apps and accelerometers allow us to see the natural world like never before. Geographer James Cheshire and designer Oliver Uberti take you to the forefront of this animal-tracking revolution. Meet the scientists gathering wild data - from seals mapping the sea to baboons making decisions, from birds dodging tornadoes to jaguars taking selfies. Join the journeys of sharks, elephants, bumblebees, snowy owls, and a wolf looking for love. Find an armchair, cancel your plans and go where the animals go.[Praise for London: The Information Capital] 'The book is infinitely compelling, one you'll return to time and again, and full of 'wow, you have to see this' moments. It reinforces the notion that information really can be beautiful...' Londonist[Praise for London: The Information Capital] 'Brilliantly compelling...The Information Capital is a tour de force in the modern use of graphics to make a point' London Evening Standard

    A group of young scientists, under the guidance of Dr. George Church, the most brilliant geneticist of our time, works to make fantasy reality by sequencing the DNA of a frozen woolly mammoth harvested from above the Arctic circle, and splicing elements of that sequence into the DNA of a modern elephant. Will they be able to turn the hybrid cells into a functional embryo and bring the extinct creatures to life in our modern world?Along with Church and his team of Harvard scientists, a world-famous conservationist and a genius Russian scientist plan to turn a tract of the Siberian tundra into Pleistocene Park, populating the permafrost with ancient herbivores as a hedge against an environmental ticking time bomb.

    He also reports on the way chickens are raised today and how they are consumed. What he discovers about America’s favorite meat is not just unpleasant but a powerful indictment of our industrial food system. The process of bringing chicken to our dinner tables is unhealthy for all concerned—from farmer to factory worker to consumer. The book traces the development of the poultry industry since the Second World War, analyzing the impact of such changes as the destruction of the family farm, the processing of chicken into nuggets and patties, and the changing makeup of the industrial labor force. The author describes the lives of immigrant workers and their reception in the small towns where they live. The conclusion is clear: there has to be a better way. Striffler proposes radical but practical change, a plan that promises more humane treatment of chickens, better food for the consumer, and fair payment for food workers and farmers.

    By day he passed through mountains covered in nine feet of snow, hamlets burned and emptied by the Taliban, and communities thriving amid the remains of medieval civilizations. By night he slept on villagers' floors, shared their meals, and listened to their stories of the recent and ancient past. Along the way Stewart met heroes and rogues, tribal elders and teenage soldiers, Taliban commanders and foreign-aid workers. He was also adopted by an unexpected companion-a retired fighting mastiff he named Babur in honor of Afghanistan's first Mughal emperor, in whose footsteps the pair was following. Through these encounters--by turns touching, confounding, surprising, and funny--Stewart makes tangible the forces of tradition, ideology, and allegiance that shape life in the map's countless places in between.

    Religion, for most of history, has provided an explanation for human life and a vision of what comes after it. But in the late nineteenth and early twentieth centuries, such beliefs came under relentless pressure as new ideas—from psychiatry to evolution to communism—seemed to suggest that our fate was now in our own hands: humans could cease to be animals, defeat death, and become immortal.In The Immortalization Commission, the acclaimed political philosopher and critic John Gray takes a brilliant and frightening look at humankind’s dangerous striving toward a scientific version of immortality. Probing the parallel faiths of Bolshevik “God-builders,” who sought to reshape the planet and psychical researchers, who believed they had evidence of a nonreligious form of life after death, Gray raises fascinating questions about how such beliefs threaten the very nature of what it means to be human. He looks to philosophers, journalists, politicians, charlatans, and mass murderers who all felt driven by a specifically scientific and modern worldview and whose revolt against death resulted in a series of experiments that ravaged whole countries. An urgent examination of Darwin’s post-religious legacy, The Immortalization Commission is an important work from “one of Britain’s leading public intellectuals” (The Wall Street Journal).

    As gripping as CSI and as eye-opening as Mary Roach’s Stiff, Carney’s The Red Market sheds a blazing new light on the disturbing, billion-dollar business of trading in human body parts, bodies, and child trafficking, raising issues and exposing corruptions almost too bizarre and shocking to imagine.

    Yet, David Wootton argues, from the fifth century BC until the 1930s, doctors actually did more harm than good. In this controversial new account of the history of medicine, he asks just how much good it has done us over the years, and how much harm it continues to do today.

    Over the last two decades, it has emerged as a powerful tool for solving crimes and determining guilt and innocence. But, very recently, an important new aspect of DNA has been revealed—it contains a detailed record of evolution. That is, DNA is a living chronicle of how the marvelous creatures that inhabit our planet have adapted to its many environments, from the freezing waters of the Antarctic to the lush canopy of the rain forest.In the pages of this highly readable narrative, Sean Carroll guides the general reader on a tour of the massive DNA record of three billion years of evolution to see how the fittest are made. And what a eye-opening tour it is—one featuring immortal genes, fossil genes, and genes that bear the scars of past battles with horrible diseases. This book clinches the case for evolution, beyond any reasonable doubt.

    So little, in fact, that scientists and philosophers have, for centuries, been obsessed with what has become known as the “eel question”: Where do eels come from? What are they? Are they fish or some other kind of creature altogether? Even today, in an age of advanced science, no one has ever seen eels mating or giving birth, and we still don’t understand what drives them, after living for decades in freshwater, to swim great distances back to the ocean at the end of their lives. They remain a mystery.Drawing on a breadth of research about eels in literature, history, and modern marine biology, as well as his own experience fishing for eels with his father, Patrik Svensson writes a book about this unusual animal. In The Book of Eels, we meet renowned historical thinkers, from Aristotle to Sigmund Freud to Rachel Carson, for whom the eel was a singular obsession. And we meet the scientists who spearheaded the search for the eel’s point of origin, including Danish marine biologist Johannes Schmidt, who led research efforts in the early twentieth century, catching thousands upon thousands of eels, in the hopes of proving their birthing grounds in the Sargasso Sea.Blending memoir and nature writing, Svensson’s journey to understand the eel becomes an exploration of the human condition that delves into overarching issues about our roots and destiny, both as humans and as animals, and, ultimately, how to handle the biggest question of all: death.

    All of those organisms are rooted in a single origin, with a common code that underwrites our existence. This paradox - that our biology is indistinct from all life, yet we consider ourselves to be special - lies at the heart of who we are.In this original and entertaining tour of life on Earth, Adam Rutherford explores how many of the things once considered to be exclusively human are not: we are not the only species that communicates, makes tools, utilises fire, or has sex for reasons other than to make new versions of ourselves. Evolution has, however, allowed us to develop our culture to a level of complexity that outstrips any other observed in nature.THE BOOK OF HUMANS tells the story of how we became the creatures we are today, bestowed with the unique ability to investigate what makes us who we are. Illuminated by the latest scientific discoveries, it is a thrilling compendium of what unequivocally fixes us as animals, and reveals how we are extraordinary among them.