Armed with a healthy dose of wit and curiosity, medical journalist Randi Hutter Epstein reveals the “invigorating history” (Nature) of hormones and the age-old quest to control them through the back rooms, basements, and labs where endocrinology began.

    They have the physicists. They have the will. What they don’t have is enough “heavy water," an essential ingredient for their nuclear designs. For two years, the Nazis have occupied Norway, and with it the Vemork hydroelectric plant, a massive industrial complex nestled on a precipice of a gorge. Vemork is the world’s sole supplier of heavy water, and under the threat of death, its engineers pushed production into overtime. For the Allies, Vemork must be destroyed. But how would they reach the castle fortress high in a mountainous valley? The answer became the most dramatic commando raid of the war. The British Special Operations Executive together a brilliant scientist and eleven refugee Norwegian commandos, who, with little more than parachutes, skis, and Tommy Guns, would destroy Hitler’s nuclear ambitions and help end the reign of the Third Reich. Based on exhaustive research and never-before-seen diaries and letters of the saboteurs, The Winter Fortress is a compulsively readable narrative about a group of young men who endured soul-crushing setbacks and Gestapo hunts and survived in one of the coldest, most inhospitable places on earth to save the world from destruction.

    The threat of the disease kept ships close to home and doomed those vessels that ventured too far from port. The willful ignorance of the royal medical elite, who endorsed ludicrous medical theories based on speculative research while ignoring the life-saving properties of citrus fruit, cost tens of thousands of lives and altered the course of many battles at sea. The cure for scurvy ranks among the greatest of human accomplishments, yet its impact on history has, until now, been largely ignored.From the earliest recorded appearance of the disease in the sixteenth century, to the eighteenth century, where a man had only half a chance of surviving the scourge, to the early nineteenth century, when the British conquered scurvy and successfully blockaded the French and defeated Napoleon, Scurvy is a medical detective story for the ages, the fascinating true story of how James Lind (the surgeon), James Cook (the mariner), and Gilbert Blane (the gentleman) worked separately to eliminate the dreaded affliction.Scurvy is an evocative journey back to the era of wooden ships and sails, when the disease infiltrated every aspect of seafaring life: press gangs "recruit" mariners on the way home from a late night at the pub; a terrible voyage in search of riches ends with a hobbled fleet and half the crew heaved overboard; Cook majestically travels the South Seas but suffers an unimaginable fate. Brimming with tales of ships, sailors, and baffling bureaucracy, Scurvy is a rare mix of compelling history and classic adventure story.

    Now, in The Organ Thieves, Pulitzer Prize-nominated journalist Chip Jones exposes the horrifying inequality surrounding Tucker's death and how he was used as a human guinea pig without his family's permission or knowledge. The circumstances surrounding his death reflect the long legacy of mistreating African Americans that began more than a century before with cadaver harvesting and worse. It culminated in efforts to win the heart transplant race in the late 1960s.

    Encompassing a grand sweep of human history, A History of the World in 100 Objects begins with one of the earliest surviving objects made by human hands, a chopping tool from the Olduvai gorge in Africa, and ends with objects which characterise the world we live in today. Seen through MacGregor's eyes, history is a kaleidoscope - shifting, interconnected, constantly surprising, and shaping our world today in ways that most of us have never imagined. A stone pillar tells us about a great Indian emperor preaching tolerance to his people; Spanish pieces of eight tell us about the beginning of a global currency; and an early Victorian tea-set speaks to us about the impact of empire. An intellectual and visual feast, this is one of the most engrossing and unusual history books published in years. 'Brilliant, engagingly written, deeply researched' Mary Beard, Guardian 'A triumph: hugely popular, and rightly lauded as one of the most effective and intellectually ambitious initiatives in the making of 'public history' for many decades' Sunday Telegraph 'Highly intelligent, delightfully written and utterly absorbing ' Timothy Clifford, Spectator 'This is a story book, vivid and witty, shining with insights, connections, shocks and delights' Gillian Reynolds Daily Telegraph

    Through a series of disastrous decisions, the state government had switched the city’s water to a source that corroded Flint’s aging lead pipes. Complaints about the foul-smelling water were dismissed: the residents of Flint—a largely poor African American city of about 100,000 people—were not seen as credible, even in matters of their own lives.It took 18 months of activism and a band of dogged outsiders to force the state to admit that the water was poisonous. But this was only after 12 people died and Flint's children suffered irreparable harm. The long battle for accountability and a humane response to this man-made disaster have only just begun.In the first full-length account of this epic failure, The Poisoned City recounts the gripping story of Flint’s poisoned water through the people who caused it, suffered from it, and exposed it. It is a chronicle of one town, but could also be about any American city, all made precarious by the neglect of infrastructure and the erosion of democratic decision-making. Cities like Flint are set up to fail—and for the people who live and work in them, the consequences may be mortal.A 2019 Library of Michigan Notable Books

    Freeman offers a new and dramatically rendered portrait of American politics in its rowdiest years. Drawing on an extraordinary range of sources, she shows that today's hyperpolarized environment cannot compare with the turbulent atmosphere of the decades before the Civil War, when the U.S. Congress itself was rife with conflict. Legislative sessions were routinely punctuated by mortal threats, canings, flipped desks, and all-out slug-fests. Congressmen drew pistols and waved bowie knives at rivals. One representative even killed another in a duel. Many were bullied in an attempt to intimidate them into compliance or silence, particularly on the issue of slavery. These fights didn't happen in a vacuum. Freeman's accounts of fistfights and threats tell a larger story of how bullying, brawling, and the press - and the powerful emotions they elicited - raised tensions between North and South and fueled the coming of the war. In the process, she brings the antebellum Congress to life, revealing its rough realities - the feel, sense, and sound of it - as well as its nation-shaping import. Funny, tragic, and rivetingly told, The Field of Blood offers a front-row view of congressional mayhem and sheds new light on the careers of luminaries such as John Quincy Adams and Thomas Hart Benton, as well as introducing a host of lesser-known but no less fascinating characters. We see slaveholders silence Northerners with threats and violence. We learn how newspapers promoted conspiracy theories that helped polarize the nation. And we witness an entire legislative chamber erupt into a massive fist-throwing, spittoon-tossing battle royal. By 1860, armed congressmen, some carrying pistols sent by their constituents, fully expected bloody combat in the House. In effect, the first battles of the Civil War were fought in Congress itself. The Field of Blood demonstrates how a country can come apart as conflicts over personal honor, party loyalty, and moral principle combine and escalate. The result is a fresh understanding of the workings of American democracy and the bonds of Union on the eve of their greatest peril.

    The job: to delve into the psyche of convicted men and women to try to understand what lies behind their often brutal actions. Follow in the footsteps of Kerry Daynes, one of the most sought-after forensic psychologists in the business and consultant on major police investigations. Kerry's job has taken her to the cells of maximum-security prisons, police interview rooms, the wards of secure hospitals and the witness box of the court room. Her work has helped solve a cold case, convict the guilty and prevent a vicious attack. Spending every moment of your life staring into the darker side of life comes with a price. Kerry's frank memoir gives an unforgettable insight into the personal and professional dangers in store for a female psychologist working with some of the most disturbing men and women.

    In this amazingly comprehensible history of the universe, Simon Singh decodes the mystery behind the Big Bang theory, lading us through the development of one of the most extraordinary, important, and awe-inspiring theories in science.

    Mark Plaster takes readers beyond the ambulance bay doors into the stranger-than-fiction world of the Emergency Department. By turns heart-warming and gut-wrenching, "Night Shift" chronicles the ebb and flow of human life, in all of its unvarnished glory, as it passes through the doors of the ED.

    Now it could be the key to healing millions with genetic diseases of every type—from Alzheimer's and Parkinson's to diabetes and sickle cell anemia.In 1974, Joey O'Donnell was born with strange symptoms. His insatiable appetite, incessant vomiting, and a relentless cough—which shook his tiny, fragile body and made it difficult to draw breath—confounded doctors and caused his parents agonizing, sleepless nights. After six sickly months, his salty skin provided the critical clue: he was one of thousands of Americans with cystic fibrosis, an inherited lung disorder that would most likely kill him before his first birthday.The gene and mutation responsible for CF were found in 1989—discoveries that promised to lead to a cure for kids like Joey. But treatments unexpectedly failed and CF was deemed incurable. It was only after the Cystic Fibrosis Foundation, a grassroots organization founded by parents, formed an unprecedented partnership with a fledgling biotech company that transformative leaps in drug development were harnessed to produce groundbreaking new treatments: pills that could fix the crippled protein at the root of this deadly disease.From science writer Bijal P. Trivedi, Breath from Salt chronicles the riveting saga of cystic fibrosis, from its ancient origins to its identification in the dank autopsy room of a hospital basement, and from the CF gene's celebrated status as one of the first human disease genes ever discovered to the groundbreaking targeted genetic therapies that now promise to cure it.Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope—and a fascinating peek into the future of genetics and medicine.

    In this engrossing narrative of the Far North, enriched by her own adventurous sojourns in the Arctic, Andrea Pitzer brings Barents' three harrowing expeditions to vivid life--while giving us fascinating insights into one of history's most intrepid navigators.

    This is the story of a fateful year that prefigured the events of 1776.In The Fever of 1721, Stephen Coss brings to life an amazing cast of characters in a year that changed the course of medical history, American journalism, and colonial revolution, including Cotton Mather, the great Puritan preacher, son of the president of Harvard College; Zabdiel Boylston, a doctor whose name is on one of Boston's grand avenues; James and his younger brother Benjamin Franklin; and Elisha Cooke and his protegee; Samuel Adams.During the worst smallpox epidemic in Boston history Mather convinced Doctor Boylston to try a procedure that he believed would prevent death--by making an incision in the arm of a healthy person and implanting it with smallpox. Inoculation led to vaccination, one of the most profound medical discoveries in history. Public outrage forced Boylston into hiding, and Mather's house was firebombed.A political fever also raged. Elisha Cooke was challenging the Crown for control of the colony and finally forced Royal Governor Samuel Shute to flee Massachusetts. Samuel Adams and the Patriots would build on this to resist the British in the run-up to the American Revolution. And a bold young printer James Franklin (who was on the wrong side of the controversy on inoculation), launched America's first independent newspaper and landed in jail. His teenage brother and apprentice, Benjamin Franklin, however, learned his trade in James' shop and became a father of the Independence movement.One by one, the atmosphere in Boston in 1721 simmered and ultimately boiled over, leading to the full drama of the American Revolution.

    In the span of twelve hours, lives can be lost, life-altering medical treatment decisions made, and dreams fulfilled or irrevocably stolen. In Brown’s skilled hands--as both a dedicated nurse and an insightful chronicler of events--we are given an unprecedented view into the individual struggles as well as the larger truths about medicine in this country, and by shift’s end, we have witnessed something profound about hope and healing and humanity. Every day, Theresa Brown holds patients' lives in her hands. On this day there are four. There is Mr. Hampton, a patient with lymphoma to whom Brown is charged with administering a powerful drug that could cure him--or kill him; Sheila, who may have been dangerously misdiagnosed; Candace, a returning patient who arrives (perhaps advisedly) with her own disinfectant wipes, cleansing rituals, and demands; and Dorothy, who after six weeks in the hospital may finally go home. Prioritizing and ministering to their needs takes the kind of skill, sensitivity, and, yes, humor that enable a nurse to be a patient’s most ardent advocate in a medical system marked by heartbreaking dysfunction as well as miraculous success.

    But just before sundown on Good Friday, the community was jolted by the most powerful earthquake in American history, a catastrophic 9.2 on the Richter Scale. For four and a half minutes, the ground lurched and rolled. Streets cracked open and swallowed buildings whole. And once the shaking stopped, night fell and Anchorage went dark. The city was in disarray and sealed off from the outside world.Slowly, people switched on their transistor radios and heard a familiar woman's voice explaining what had just happened and what to do next. Genie Chance was a part-time radio reporter and working mother who would play an unlikely role in the wake of the disaster, helping to put her fractured community back together. Her tireless broadcasts over the next three days would transform her into a legendary figure in Alaska and bring her fame worldwide--but only briefly. That Easter weekend in Anchorage, Genie and a cast of endearingly eccentric characters--from a mountaineering psychologist to the local community theater group staging Our Town--were thrown into a jumbled world they could not recognize. Together, they would make a home in it again.Drawing on thousands of pages of unpublished documents, interviews with survivors, and original broadcast recordings, This Is Chance! is the hopeful, gorgeously told story of a single catastrophic weekend and proof of our collective strength in a turbulent world.There are moments when reality instantly changes--when the life we assume is stable gets upended by pure chance. This Is Chance! is an electrifying and lavishly empathetic portrayal of one community rising above the randomness, a real-life fable of human connection withstanding chaos.