The case would become one of the most famous in modern medicine—and a total failure. As Nature Made Him tells the extraordinary story of David Reimer, who, when finally informed of his medical history, made the decision to live as a male. A macabre tale of medical arrogance, it is first and foremost a human drama of one man's—and one family's—amazing survival in the face of terrible odds.

    It also makes him enormously vulnerable. Eli lacks the innate skepticism that will help his peers navigate adolescence more safely—and vastly more successfully. Journalist Jennifer Latson follows Eli over three critical years of his life as his mother, Gayle, must decide whether to shield Eli entirely from the world and its dangers or give him the freedom to find his own way and become his own person. By intertwining Eli and Gayle’s story with the science and history of Williams syndrome, the book explores the genetic basis of behavior and the quirks of human nature. More than a case study of a rare disorder, however, The Boy Who Loved Too Much is a universal tale about the joys and struggles of raising a child, of growing up, and of being different.

    But I was getting there. I wanted the world to know that all of this pain I had been feeling…that it was related to my vagina. Thus, Vagina Problems was born. It was a cutesy name. It was my way of taking this pain and saying, “Whatever. I’m here. I have it. It sucks. Let’s talk about it.”In April 2014, Deputy Editorial Director at BuzzFeed Lara Parker opened up to the world in an article on the website: she suffers from endometriosis. And beyond that? She let the whole world know that she wasn’t having any sex, as sex was excruciatingly painful. Less than a year before, she received not only the diagnosis of endometriosis, but also a diagnosis of pelvic floor dysfunction, vulvodynia, vaginismus, and vulvar vestibulitis. Combined, these debilitating conditions have wreaked havoc on her life, causing excruciating pain throughout her body since she was fourteen years old. These are her Vagina Problems. It was five years before Lara learned what was happening to her body. Five years of doctors insisting she just had “bad period cramps,” or implying her pain was psychological. Shamed and stigmatized, Lara fought back against a medical community biased against women and discovered that the ignorance of many doctors about women’s anatomy was damaging more than just her own life. One in ten women have endometriosis and it takes an average of seven years before they receive an accurate diagnosis—or any relief from this incurable illness’ chronic pain. With candid revelations about her vaginal physical therapy, dating as a straight woman without penetrative sex, coping with painful seizures while at the office, diet and wardrobe malfunctions when your vagina hurts all the time, and the depression and anxiety of feeling unloved, Lara tackles it all in Vagina Problems: Endometriosis, Painful Sex, and Other Taboo Topics with courage, wit, love, and a determination to live her best life."

    An orphaned niece of President Theodore Roosevelt, she converted her Gilded Age childhood of denial and secrecy into an irreconcilable marriage with her ambitious fifth cousin Franklin. Despite their inability to make each other happy, Franklin Roosevelt transformed Eleanor from a settlement house volunteer on New York’s Lower East Side into a matching partner in New York’s most important power couple in a generation. When Eleanor discovered Franklin’s betrayal with her younger, prettier social secretary, Lucy Mercer, she offered a divorce and vowed to face herself honestly. Here is an Eleanor both more vulnerable and more aggressive, more psychologically aware and sexually adaptable than we knew. She came to accept FDR’s bond with his executive assistant, Missy LeHand; she allowed her children to live their own lives, as she never could; and she explored her sexual attraction to women, among them a star female reporter on FDR’s first presidential campaign, and younger men. Eleanor needed emotional connection. She pursued deeper relationships wherever she could find them. Throughout her life and travels, there was always another person or place she wanted to heal. As FDR struggled to recover from polio, Eleanor became a voice for the voiceless, her husband’s proxy in presidential ambition, and then the people’s proxy in the White House. Later, she would be the architect of international human rights and world citizen of the Atomic Age, urging Americans to cope with the anxiety of global annihilation by cultivating a “world mind.” She insisted that we cannot live for ourselves alone but must learn to live together or we will die together. Drawing on new research, Michaelis’s riveting portrait is not just a comprehensive biography of a major American figure, but the story of an American ideal: how our freedom is always a choice. Eleanor rediscovers a model of what is noble and evergreen in the American character, a model we need today more than ever.

    Anyone will tell you that! But for all the rosy sentiments surrounding friendship, most people don’t talk much about what it really takes to stay close for the long haul.Now two friends, Aminatou Sow and Ann Friedman, tell the story of their equally messy and life-affirming Big Friendship in this honest and hilarious book that chronicles their first decade in one another’s lives. As the hosts of the hit podcast Call Your Girlfriend, they’ve become known for frank and intimate conversations. In this book, they bring that energy to their own friendship—its joys and its pitfalls. An inspiring and entertaining testament to the power of society’s most underappreciated relationship, Big Friendship will invite you to think about how your own bonds are formed, challenged, and preserved. It is a call to value your friendships in all of their complexity. Actively choose them. And, sometimes, fight for them.

    Parents and family members who never thought they could get inside the head of their autistic loved one, at last, have a way to break through to the curious, subtle, and complex life within.Using an alphabet grid to painstakingly construct words, sentences, and thoughts that he is unable to speak out loud, Naoki answers even the most delicate questions that people want to know. Questions such as: “Why do people with autism talk so loudly and weirdly?” “Why do you line up your toy cars and blocks?” “Why don’t you make eye contact when you’re talking?” and “What’s the reason you jump?” (Naoki’s answer: “When I’m jumping, it’s as if my feelings are going upward to the sky.”) With disarming honesty and a generous heart, Naoki shares his unique point of view on not only autism but life itself. His insights—into the mystery of words, the wonders of laughter, and the elusiveness of memory—are so startling, so strange, and so powerful that you will never look at the world the same way again.

    Kim Barker is not your typical, impassive foreign correspondent—she is candid, self-deprecating, laugh-out-loud funny. At first an awkward newbie in Afghanistan, she grows into a wisecracking, seasoned reporter with grave concerns about our ability to win hearts and minds in the region. In The Taliban Shuffle, Barker offers an insider’s account of the “forgotten war” in Afghanistan and Pakistan, chronicling the years after America’s initial routing of the Taliban, when we failed to finish the job. When Barker arrives in Kabul, foreign aid is at a record low, electricity is a pipe dream, and of the few remaining foreign troops, some aren’t allowed out after dark. Meanwhile, in the vacuum left by the U.S. and NATO, the Taliban is regrouping as the Afghan and Pakistani governments floun­der. Barker watches Afghan police recruits make a travesty of practice drills and observes the disorienting turnover of diplomatic staff. She is pursued romantically by the former prime minister of Pakistan and sees adrenaline-fueled col­leagues disappear into the clutches of the Taliban. And as her love for these hapless countries grows, her hopes for their stability and security fade. Swift, funny, and wholly original, The Taliban Shuffle unforgettably captures the absurdities and tragedies of life in a war zone.

    As the creator and star of Mister Rogers’ Neighborhood, he was a champion of compassion, equality, and kindness. Rogers was fiercely devoted to children and to taking their fears, concerns, and questions about the world seriously.The Good Neighbor, the first full-length biography of Fred Rogers, tells the story of this utterly unique and enduring American icon. Drawing on original interviews, oral histories, and archival documents, Maxwell King traces Rogers’s personal, professional, and artistic life through decades of work, including a surprising decision to walk away from the show to make television for adults, only to return to the neighborhood with increasingly sophisticated episodes, written in collaboration with experts on childhood development. An engaging story, rich in detail, The Good Neighbor is the definitive portrait of a beloved figure, cherished by multiple generations.

    She also lectures widely on autism—because Temple Grandin is autistic, a woman who thinks, feels, and experiences the world in ways that are incomprehensible to the rest of us. In this unprecedented book, Grandin delivers a report from the country of autism. Writing from the dual perspectives of a scientist and an autistic person, she tells us how that country is experienced by its inhabitants and how she managed to breach its boundaries to function in the outside world. What emerges in Thinking in Pictures is the document of an extraordinary human being, one who, in gracefully and lucidly bridging the gulf between her condition and our own, sheds light on the riddle of our common identity.

    While it's true our ER doesn't see the stabbing and gunshot action ERs see in inner cities, we have no shortage of the sad, the scary, the painful, and the just plain dumb. With more than 20 stories, things ER workers want to say to patients, and Emergency Room BINGO, 'A Double Dose of Dilaudid' will take you on a joyride to the funnier side of the ER. See what a bored husband did to get out of a date night with his wife, learn what happens when you try to make your own meth, and read about items men and women have inserted in their bodies.

    Inside you will find:× The smell of honeysuckle× Heartbreak× A French-kissing rabbit× A haunted house× Death× A vagina singing sad old songs× Young geraniums in an ancient castle× Birth× A dog who appears in dreams as a spiritual guide× Divorce× Electromagnetic energy fields× Emotional horniness× The ghost of a sea captain× And moreI hope you enjoy these little weirds.Love,Jenny Slate

    That list, which included “You won’t have to shout at me that I’m deaf,” and “I won’t blame the family dog for my incontinence,” became the basis of this rousing collection of dos and don’ts, wills and won’ts that is equal parts hilarious, honest, and practical.The fact is, we don’t want to age the way previous generations did. “Old people” hoard. They bore relatives—and strangers—with tales of their aches and pains. They insist on driving long after they’ve become a danger to others (and themselves). They eat dinner at 4pm. They swear they don’t need a cane or walker (and guess what happens next). They never, ever apologize. But there is another way . . .In Stupid Things I Won’t Do When I’m Old, Petrow candidly addresses the fears, frustrations, and stereotypes that accompany aging. He offers a blueprint for the new old age, and an understanding that aging and illness are not the same. As he writes, “I meant the list to serve as a pointed reminder—to me—to make different choices when I eventually cross the threshold to ‘old.’”Getting older is a privilege. This essential guide reveals how to do it with grace, wisdom, humor, and hope. And without hoarding.

    Told with sincerity, humor, and wit, Ilgunas's story is both a fascinating account of one man's remarkable journey along the pipeline's potential path and a meditation on climate change, the beauty of the natural world, and the extremes to which we can push ourselves--both physically and mentally. It started as a far-fetched idea--to hike the entire length of the proposed route of the Keystone XL pipeline. But in the months that followed, it grew into something more for Ken Ilgunas. It became an irresistible adventure--an opportunity not only to draw attention to global warming but also to explore his personal limits. So in September 2012, he strapped on his backpack, stuck out his thumb on the interstate just north of Denver, and hitchhiked 1,500 miles to the Alberta tar sands. Once there, he turned around and began his 1,700-mile trek to the XL's endpoint on the Gulf Coast of Texas, a journey he would complete entirely on foot, walking almost exclusively across private property.Both a travel memoir and a reflection on climate change, Trespassing Across America is filled with colorful characters, harrowing physical trials, and strange encounters with the weather, terrain, and animals of America's plains. A tribute to the Great Plains and the people who live there, Ilgunas's memoir grapples with difficult questions about our place in the world: What is our personal responsibility as stewards of the land? As members of a rapidly warming planet? As mere individuals up against something as powerful as the fossil fuel industry? Ultimately, Trespassing Across America is a call to embrace the belief that a life lived not half wild is a life only half lived.

    Personal, poignant, and meticulously precise, these stories evoke Chekhov, Maugham, and William Carlos Williams, admitting readers to the beating heart of medicine. Internal Medicine is an account of what it means to be a doctor, to be mortal, and to be human.

    That means most people alive today will spend more years in elderhood than in childhood, and many will be elders for 40 years or more. Yet at the very moment that humans are living longer than ever before, we've made old age into a disease, a condition to be dreaded, denigrated, neglected, and denied. Reminiscent of Oliver Sacks, noted Harvard-trained geriatrician Louise Aronson uses stories from her quarter century of caring for patients, and draws from history, science, literature, popular culture, and her own life to weave a vision of old age that's neither nightmare nor utopian fantasy--a vision full of joy, wonder, frustration, outrage, and hope about aging, medicine, and humanity itself. Elderhood is for anyone who is, in the author's own words, "an aging, i.e., still-breathing human being."