It's harrowing, tender-hearted, and funny as hell. O'Connell proves himself to be a genius guide through all the circles of imagined and anticipated doom." --Jenny Offill By the author of the award-winning To Be a Machine, an absorbing, deeply felt book about our anxious present tense--and coming to grips with the futureWe're alive in a time of worst-case scenarios: The weather has gone uncanny. Our old postwar alliances are crumbling. Everywhere you look there's an omen, a joke whose punchline is the end of the world. How is a person supposed to live in the shadow of such a grim future? What does it mean to have children--nothing if not an act of hope? What might it be like to live through the worst? And what on Earth is anybody doing about it?Dublin-based writer Mark O'Connell is consumed by these questions--and, as the father of two young children himself, he finds them increasingly urgent. In Notes from an Apocalypse, he crosses the globe in pursuit of answers. He tours survival bunkers in South Dakota. He ventures to New Zealand, a favored retreat of billionaires banking on civilization's collapse. He engages with would-be Mars colonists, preppers, right-wing conspiracists. And he bears witness to those places, like Chernobyl, that the future has already visited--real-life portraits of the end of the world as we know it. In doing so, he comes to a resolution, while offering readers a unique window into our contemporary imagination.Both investigative and deeply personal, Notes from an Apocalypse is an affecting, humorous, and surprisingly hopeful meditation on our present moment. With insight, humanity, and wit, O'Connell leaves you to wonder: What if the end of the world isn't the end of the world?

    As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    Our bodies are hardwired for sweets, so food giants have developed fifty-six types of sugar to add to their products, creating in us the expectation that everything should be cloying; we've evolved to prefer fast, convenient meals, hence our modern-day preference for ready-to-eat foods. Moss goes on to show how the processed food industry--including major companies like Nestlé, Mars, and Kellogg's--has tried not only to evade this troubling discovery about the addictiveness of food but to actually exploit it. For instance, in response to recent dieting trends, food manufacturers have simply turned junk food into junk diets, filling grocery stores with "diet" foods that are hardly distinguishable from the products that got us into trouble in the first place. As obesity rates continue to climb, manufacturers are now claiming to add ingredients that can effortlessly cure our compulsive eating habits. An account of the legal battles, insidious marketing campaigns, and cutting-edge food science that have brought us to our current public health crisis, Moss lays out all that the food industry is doing to exploit and deepen our addictions, and shows us why what we eat has never mattered more.From the #1 New York Times bestselling author of Salt Sugar Fat comes a powerful exposé of how the processed food industry exploits our evolutionary instincts, the emotions we associate with food, and legal loopholes in their pursuit of profit over public health.

    Darwin wondered why these birds were confined to remote islands at the tip of South America, sensing a larger story, but he set this mystery aside and never returned to it. Almost two hundred years later, Jonathan Meiburg takes up this chase. He takes us through South America, from the fog-bound coasts of Tierra del Fuego to the tropical forests of Guyana, in search of these birds: striated caracaras, which still exist, though they're very rare. He reveals the wild, fascinating story of their history, origins, and possible futures. And along the way, he draws us into the life and work of William Henry Hudson, the Victorian writer and naturalist who championed caracaras as an unsung wonder of the natural world, and to falconry parks in the English countryside, where captive caracaras perform incredible feats of memory and problem-solving. A Most Remarkable Creature is a hybrid of science writing, travelogue, and biography, as generous and accessible as it is sophisticated, and absolutely riveting.

    Then make it better.I am 94. I've had an extraordinary life. It's only now that I appreciate how extraordinary.As a young man, I felt I was out there in the wild, experiencing the untouched natural world - but it was an illusion. The tragedy of our time has been happening all around us, barely noticeable from day to day - the loss of our planet's wild places, its biodiversity.I have been witness to this decline. A Life on Our Planet is my witness statement, and my vision for the future. It is the story of how we came to make this, our greatest mistake - and how, if we act now, we can yet put it right.We have one final chance to create the perfect home for ourselves and restore the wonderful world we inherited.All we need is the will to do so.

    Its presence in nature was dismissed as a desperate response to starvation or other life-threatening circumstances, and few spent time studying it. A taboo subject in our culture, the behavior was portrayed mostly through horror movies or tabloids sensationalizing the crimes of real-life flesh-eaters. But the true nature of cannibalism--the role it plays in evolution as well as human history--is even more intriguing (and more normal) than the misconceptions we've come to accept as fact. In Cannibalism: A Perfectly Natural History, zoologist Bill Schutt sets the record straight, debunking common myths and investigating our new understanding of cannibalism's role in biology, anthropology, and history in the most fascinating account yet written on this complex topic. Schutt takes readers from Arizona's Chiricahua Mountains, where he wades through ponds full of tadpoles devouring their siblings, to the Sierra Nevadas, where he joins researchers who are shedding new light on what happened to the Donner Party--the most infamous episode of cannibalism in American history. He even meets with an expert on the preparation and consumption of human placenta (and, yes, it goes well with Chianti). Bringing together the latest cutting-edge science, Schutt answers questions such as why some amphibians consume their mother's skin; why certain insects bite the heads off their partners after sex; why, up until the end of the twentieth century, Europeans regularly ate human body parts as medical curatives; and how cannibalism might be linked to the extinction of the Neanderthals. He takes us into the future as well, investigating whether, as climate change causes famine, disease, and overcrowding, we may see more outbreaks of cannibalism in many more species--including our own.Cannibalism places a perfectly natural occurrence into a vital new context and invites us to explore why it both enthralls and repels us.

    The media seized hold of the story and, in the process, helped to launch one of the most devastating health scares ever. In the years to come Wakefield would be revealed as a profiteer in league with class-action lawyers, and he would eventually lose his medical license. Meanwhile, one study after another failed to find any link between childhood vaccines and autism. Yet the myth that vaccines somehow cause developmental disorders lives on. Despite the lack of corroborating evidence, it has been popularized by media personalities such as Oprah Winfrey and Jenny McCarthy and legitimized by journalists who claim that they are just being fair to “both sides” of an issue about which there is little debate. Meanwhile, millions of dollars have been diverted from potential breakthroughs in autism research; families have spent their savings on ineffective “miracle cures"; and declining vaccination rates have led to outbreaks of deadly illnesses like Hib, measles, and whooping cough. Most tragic of all is the increasing number of children dying from vaccine-preventable diseases. In The Panic Virus Seth Mnookin draws on interviews with parents, public-health advocates, scientists, and anti-vaccine activists to tackle a fundamental question: How do we decide what the truth is? The fascinating answer helps explain everything from the persistence of conspiracy theories about 9/11 to the appeal of talk-show hosts who demand that President Obama “prove” he was born in America. The Panic Virus is the ultimate cautionary tale for our time.

    Two scientists explore the potential of a revolutionary genetics technology capable of easily and affordably manipulating DNA in human embryos to prevent specific diseases, addressing key concerns about related ethical and societal repercussions.

    Taking us into a landscape most of us have never before seen, award-winning journalist Barbara Demick brings to life what it means to be living under the most repressive totalitarian regime today—an Orwellian world that is by choice not connected to the Internet, in which radio and television dials are welded to the one government station, and where displays of affection are punished; a police state where informants are rewarded and where an offhand remark can send a person to the gulag for life. Demick takes us deep inside the country, beyond the reach of government censors. Through meticulous and sensitive reporting, we see her six subjects—average North Korean citizens—fall in love, raise families, nurture ambitions, and struggle for survival. One by one, we experience the moments when they realize that their government has betrayed them.  Nothing to Envy is a groundbreaking addition to the literature of totalitarianism and an eye-opening look at a closed world that is of increasing global importance.

    It’s so bound up with our deepest feelings that emotional trauma causes it to change shape.Practising cardiologist Sandeep Jauhar beautifully weaves his own experiences with the defining discoveries of the past to tell the story of our most vital organ. He looks at some of the pioneers who risked their careers and their patients’ lives to better understand the heart. People like Daniel Hale Williams, who performed the world’s first documented heart surgery, and Wilson Greatbatch, who accidentally invented the pacemaker.Amid gripping scenes from the operating theatre, Jauhar interweaves stories about the patients he’s treated with the moving tale of his family’s own history of heart problems, from his grandfather’s sudden death in India – an event that sparked his life-long obsession – to the ominous signs of how he himself might die.He also confronts the limits of medical technology and argues that future progress will be determined more by how we choose to live rather than by any device we invent.

    When temperatures drop below 56°F, tin crumbles into powder. Were the soldiers of the Grande Armée acutee fatally weakened by cold because the buttons of their uniforms fell apart? How different our world might be if tin did not disintegrate at low temperatures and the French had continued their eastward expansion! This fascinating book tells the stories of seventeen molecules that, like the tin of those buttons, greatly influenced the course of history. These molecules provided the impetus for early exploration and made possible the ensuing voyages of discovery. They resulted in grand feats of engineering and spurred advances in medicine; lie behind changes in gender roles, in law, and in the environment; and have determined what we today eat, drink, and wear. Showing how a change as small as the position of an atom can lead to enormous differences in the properties of a substance, the authors reveal the astonishing chemical connections among seemingly unrelated events. Napoleon's Buttons offers a novel way to understand how our contemporary world works and how our civilization has been shaped over time.

    Barnett was only a law student when she came across the case that would change her life forever--that of Sharanda Jones, single mother, business owner and, like Brittany, black daughter of the rural South. A victim of America's ruthless and devastating war on drugs, Sharanda had been torn from the arms of her young daughter and was serving a life sentence without parole--all for a first-time drug offense. In Sharanda, Brittany saw haunting echoes of own life, both as the daughter of a formerly incarcerated mother and the one-time girlfriend of an abusive drug dealer. As she studied Sharanda's case, a system slowly came into focus: one where widespread racial injustice forms the core of our country's addiction to incarceration. Moved by Sharanda's plight, Brittany began to work towards her freedom.This had never been the plan. Bright and ambitious, Brittany was already a successful accountant with her sights set on a high-powered future in corporate law. But Sharanda's case opened the door to a harrowing journey through the criminal justice system, in which people could be locked up for life under misguided appeals for law and order. Driven by the realization that her clients' fates could have easily been her own, Brittany soon found herself on a quest to unlock the human potential of those our society has forgotten how to see. Living a double life, she moved billion dollar corporate deals by day, and by night worked pro bono to free Sharanda and others in near-impossible legal battles. Ultimately, her journey transformed her understanding of injustice in the courts, of genius languishing behind bars, and the very definition of freedom itself. A Knock at Midnight is Brittany's riveting, inspirational memoir, at once a coming-of-age story and a powerful evocation of what it takes to bring hope and justice to a system built to resist both at every turn.

    But what is time, exactly? Do children experience it the same way adults do? Why does it seem to slow down when we’re bored and speed by as we get older? How and why does time fly?In this witty and meditative exploration, award-winning author and New Yorker staff writer Alan Burdick takes readers on a personal quest to understand how time gets in us and why we perceive it the way we do. In the company of scientists, he visits the most accurate clock in the world (which exists only on paper); discovers that “now” actually happened a split-second ago; finds a twenty-fifth hour in the day; lives in the Arctic to lose all sense of time; and, for one fleeting moment in a neuroscientist’s lab, even makes time go backward. Why Time Flies is an instant classic, a vivid and intimate examination of the clocks that tick inside us all.

    a riveting adventure."--OutsideShivering, exhausted, gasping for oxygen, beyond doubt . . . A hundred-year mystery lured veteran climber Mark Synnott into an unlikely expedition up Mount Everest during the spring 2019 season that came to be known as "the Year Everest Broke." What he found was a gripping human story of impassioned characters from around the globe and a mountain that will consume your soul--and your life--if you let it.The mystery? On June 8, 1924, George Mallory and Sandy Irvine set out to stand on the roof of the world, where no one had stood before. They were last seen eight hundred feet shy of Everest's summit still "going strong" for the top. Could they have succeeded decades before Sir Edmund Hillary and Tenzing Norgay? Irvine is believed to have carried a Kodak camera with him to record their attempt, but it, along with his body, had never been found. Did the frozen film in that camera have a photograph of Mallory and Irvine on the summit before they disappeared into the clouds, never to be seen again? Kodak says the film might still be viable. . . .Mark Synnott made his own ascent up the infamous North Face along with his friend Renan Ozturk, a filmmaker using drones higher than any had previously flown. Readers witness first-hand how Synnott's quest led him from oxygen-deprivation training to archives and museums in England, to Kathmandu, the Tibetan high plateau, and up the North Face into a massive storm. The infamous traffic jams of climbers at the very summit immediately resulted in tragic deaths. Sherpas revolted. Chinese officials turned on Synnott's team. An Indian woman miraculously crawled her way to frostbitten survival. Synnott himself went off the safety rope--one slip and no one would have been able to save him--committed to solving the mystery.Eleven climbers died on Everest that season, all of them mesmerized by an irresistible magic. The Third Pole is a rapidly accelerating ride to the limitless joy and horror of human obsession.

    Beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in the sequencing of the Neanderthal genome in 2010, Neanderthal Man describes the events, intrigues, failures, and triumphs of these scientifically rich years through the lens of the pioneer and inventor of the field of ancient DNA.We learn that Neanderthal genes offer a unique window into the lives of our hominin relatives and may hold the key to unlocking the mystery of why humans survived while Neanderthals went extinct. Drawing on genetic and fossil clues, Pääbo explores what is known about the origin of modern humans and their relationship to the Neanderthals and describes the fierce debate surrounding the nature of the two species’ interactions. His findings have not only redrawn our family tree, but recast the fundamentals of human history—the biological beginnings of fully modern Homo sapiens, the direct ancestors of all people alive today.A riveting story about a visionary researcher and the nature of scientific inquiry, Neanderthal Man offers rich insight into the fundamental question of who we are.