Inheritance Conventional wisdom dictates that our genetic destiny is fixed at conception. But Dr. Moalem's groundbreaking book shows us that the human genome is far more fluid and fascinating than your ninth grade biology teacher ever imagined. By bringing us to the bedside of his unique and complex patients, he masterfully demonstrates what rare genetic conditions can teach us all about our own health and well-being. In the brave new world we're rapidly rocketing into, genetic knowledge has become absolutely crucial. Inheritance provides an indispensable roadmap for this journey by teaching you: -Why you may have recovered from the psychological trauma caused by childhood bullying-but your genes may remain scarred for life. -How fructose is the sugar that makes fruits sweet-but if you have certain genes, consuming it can buy you a one-way trip to the coroner's office. -Why ingesting common painkillers is like dosing yourself repeatedly with morphine-if you have a certain set of genes. -How insurance companies legally use your genetic data to predict the risk of disability for you and your children-and how that impacts the coverage decisions they make for your family. -How to have the single most important conversation with your doctor-one that can save your life. And finally: -Why people with rare genetic conditions hold the keys to medical problems affecting millions. In this trailblazing book, Dr. Moalem employs his wide-ranging and entertaining interdisciplinary approach to science and medicine-- explaining how art, history, superheroes, sex workers, and sports stars all help us understand the impact of our lives on our genes, and our genes on our lives. Inheritance will profoundly alter how you view your genes, your health--and your life.

    Famed for his dictatorial style, his political cunning and admired – initially – by Hitler, Mussolini led the National Fascist Party and ruled Italy as Prime Minister from 1922 until his ousting in 1943. In so doing, he paved the way towards Italy’s defeat in World War Two, and some of the 20th century’s most destructive ideologies and practices.Following expulsion from Italian Socialist Party, Mussolini denounced all efforts of class conflict, and instead later commanded a Fascist March on Rome to become the youngest Prime Minister in Italian history. Thereafter he set about dismantling the apparatus of democracy and initiated what would become known as the one-party totalitarian state. With World War II came defeat, humiliation and his bloody deposing. Explaining his ideologies, policies, actions and flaws, ‘Mussolini: History in an Hour’ is the concise life of the man whose ideas helped create some of the worst horrors of the modern history.Love history? Know your stuff with History in an Hour…

    The Great War was over and American optimism was higher than the stock market. What better moment to launch an expedition to Antarctica, the planet’s final frontier? There wouldn’t be another encounter with an unknown this magnificent until Neil Armstrong stepped onto the moon.Everyone wanted in on the adventure. Rockefellers and Vanderbilts begged to be taken along as mess boys, and newspapers across the globe covered the planning’s every stage. And then, the night before the expedition’s flagship set off, Billy Gawronski—a mischievous, first-generation New York City high schooler desperate to escape a dreary future in the family upholstery business—jumped into the Hudson River and snuck aboard.Could he get away with it?From the soda shops of New York’s Lower East Side to the dance halls of sultry Francophone Tahiti, all the way to Antarctica’s blinding white and deadly freeze, Laurie Gwen Shapiro’s The Stowaway takes you on the unforgettable voyage of a plucky young stowaway who became a Jazz Age celebrity, a mascot for an up-by-your bootstraps era.

    Using glorious, colorful graphics, Mark Ovenden traces the history of mass transit-including rare and historic maps, diagrams, and photographs, some available for the first time since their original publication. Transit Maps is the graphic designer's new bible, the transport enthusiast's dream collection, and a coffee-table essential for everyone who's ever traveled in a city.

    For the past two millennia, the ability to produce it in ever more efficient ways has supported the proliferation of literacy, media, religion, education, commerce, and art; it has formed the foundation of civilizations, promoting revolutions and restoring stability. One has only to look at history’s greatest press run, which produced 6.5 billion copies of Máo zhuxí yulu, Quotations from Chairman Mao Tse-tung (Zedong)—which doesn’t include editions in 37 foreign languages and in braille—to appreciate the range and influence of a single publication, in paper. Or take the fact that one of history’s most revered artists, Leonardo da Vinci, left behind only 15 paintings but 4,000 works on paper. And though the colonies were at the time calling for a boycott of all British goods, the one exception they made speaks to the essentiality of the material; they penned the Declaration of Independence on British paper.Now, amid discussion of “going paperless”—and as speculation about the effects of a digitally dependent society grows rampant—we’ve come to a world-historic juncture. Thousands of years ago, Socrates and Plato warned that written language would be the end of “true knowledge,” replacing the need to exercise memory and think through complex questions. Similar arguments were made about the switch from handwritten to printed books, and today about the role of computer technology. By tracing paper’s evolution from antiquity to the present, with an emphasis on the contributions made in Asia and the Middle East, Mark Kurlansky challenges common assumptions about technology’s influence, affirming that paper is here to stay. Paper will be the commodity history that guides us forward in the twenty-first century and illuminates our times.

    His magnificent new biography of Ludwig van Beethoven peels away layers of legend to get to the living, breathing human being who composed some of the world’s most iconic music. Swafford mines sources never before used in English-language biographies to reanimate the revolutionary ferment of Enlightenment-era Bonn, where Beethoven grew up and imbibed the ideas that would shape all of his future work. Swafford then tracks his subject to Vienna, capital of European music, where Beethoven built his career in the face of critical incomprehension, crippling ill health, romantic rejection, and “fate’s hammer,” his ever-encroaching deafness. Throughout, Swafford offers insightful readings of Beethoven’s key works. More than a decade in the making, this will be the standard Beethoven biography for years to come.

    Now, in this gripping narrative, Jill Jonnes tells this fascinating story?a high-stakes drama that pitted the money and will of the nation's mightiest railroad against the corruption of Tammany Hall, the unruly forces of nature, and the machinations of labor agitators. In 1901, the president of the Pennsylvania Railroad, Alexander Cassatt, determined that it was technically feasible to build a system of tunnels connecting Manhattan to New Jersey and Long Island. Confronted by payoff-hungry politicians, brutal underground working conditions, and disastrous blowouts and explosions, it would take him nearly a decade to make Penn Station and its tunnels a reality. Set against the bustling backdrop of Gilded Age New York, "Conquering Gotham" will enthrall fans of David McCullough's "The Great Bridge" and Ron Chernow's "Titan."

    A local priest got 120 released, many with broken ankles and other marks of abuse, but the rest vanished. Óscar Martínez, a young writer from El Salvador, was in Altar soon after the abduction, and his account of the migrant disappearances is only one of the harrowing stories he garnered from two years spent traveling up and down the migrant trail from Central America and across the US border. More than a quarter of a million Central Americans make this increasingly dangerous journey each year, and each year as many as 20,000 of them are kidnapped.Martínez writes in powerful, unforgettable prose about clinging to the tops of freight trains; finding respite, work and hardship in shelters and brothels; and riding shotgun with the border patrol. Illustrated with stunning full-color photographs, The Beast is the first book to shed light on the harsh new reality of the migrant trail in the age of the narcotraficantes.

    In the style of Studs Terkel (Working, Hard Times, The Good War) and Dave Isay (Listening Is an Act of Love), Londoners offers up  the stories, the gripes, the memories, and the dreams of those in the great and vibrant British metropolis who “love it, hate it, live it, left it, and long for it,” from a West End rickshaw driver to a Soldier of the Guard at Buckingham Palace to a recovering heroin addict seeing Big Ben for the very first time. Published just in time for the 2012 London Olympic Games, Londoners is a glorious literary celebration of one of the world’s truly great cities.

    Yet despite a century of medical progress, viral and bacterial disasters continue to take us by surprise, inciting panic and dominating news cycles. From the Spanish flu to the 1924 outbreak of pneumonic plague in Los Angeles to the 1930 “parrot fever” pandemic, through the more recent SARS, Ebola, and Zika epidemics, the last one hundred years have been marked by a succession of unanticipated pandemic alarms.In The Pandemic Century, a lively account of scares both infamous and less known, Mark Honigsbaum combines reportage with the history of science and medical sociology to artfully reconstruct epidemiological mysteries and the ecology of infectious diseases. We meet dedicated disease detectives, obstructive or incompetent public health officials, and brilliant scientists often blinded by their own knowledge of bacteria and viruses. We also see how fear of disease often exacerbates racial, religious, and ethnic tensions—even though, as the epidemiologists Malik Peiris and Yi Guan write, “‘nature’ remains the greatest bioterrorist threat of all.”Like man-eating sharks, predatory pathogens are always present in nature, waiting to strike; when one is seemingly vanquished, others appear in its place. These pandemics remind us of the limits of scientific knowledge, as well as the role that human behavior and technologies play in the emergence and spread of microbial diseases.

    Combining linguistics and cultural history, Gaston Dorren takes us on an intriguing tour of the continent, from Proto-Indo-European (the common ancestor of most European languages) to the rise and rise of English, via the complexities of Welsh plurals and Czech pronunciation. Along the way we learn why Esperanto will never catch on, how the language of William the Conqueror lives on in the Channel Islands and why Finnish is the easiest European language.Surprising, witty and full of extraordinary facts, this book will change the way you think about the languages around you. Polyglot Gaston Dorren might even persuade you that English is like Chinese.

    Roads bind our world--metaphorically and literally--transforming landscapes and the lives of the people who inhabit them. Roads have unparalleled power to impact communities, unite worlds and sunder them, and reveal the hopes and fears of those who travel them. With his marvelous eye for detail and his contagious enthusiasm, Ted Conover explores six of these key byways worldwide. In Peru, he traces the journey of a load of rare mahogany over the Andes to its origin, an untracked part of the Amazon basin soon to be traversed by a new east-west route across South America. In East Africa, he visits truckers whose travels have been linked to the worldwide spread of AIDS. In the West Bank, he monitors highway checkpoints with Israeli soldiers and then passes through them with Palestinians, witnessing the injustices and danger borne by both sides. He shuffles down a frozen riverbed with teenagers escaping their Himalayan valley to see how a new road will affect the now-isolated Indian region of Ladakh. From the passenger seat of a new Hyundai piling up the miles, he describes the exuberant upsurge in car culture as highways proliferate across China. And from inside an ambulance, he offers an apocalyptic but precise vision of Lagos, Nigeria, where congestion and chaos on freeways signal the rise of the global megacity. A spirited, urgent book that reveals the costs and benefits of being connected--how, from ancient Rome to the present, roads have played a crucial role in human life, advancing civilization even as they set it back.

    From Marilyn Monroe's borderline personality disorder to Charles Darwin's anxiety, Kalb provides compelling insight into a broad range of maladies, using historical records and interviews with leading mental health experts, biographers, sociologists, and other specialists. Packed with intriguing revelations, this smart narrative brings a new perspective to one of the hottest new topics in today's cultural conversation.

    Why spend time wandering around a country that remains a sort of dead zone for many foreigners, surrounded as it is by a force field of historical, linguistic, climatic, and gastronomic barriers? Winder's book is propelled by a wish to reclaim the brilliant, chaotic, endlessly varied German civilization that the Nazis buried and ruined, and that, since 1945, so many Germans have worked to rebuild.Germania is a very funny book on serious topics — how we are misled by history, how we twist history, and how sometimes it is best to know no history at all. It is a book full of curiosities: odd food, castles, mad princes, fairy tales, and horse-mating videos. It is about the limits of language, the meaning of culture, and the pleasure of townscape.

    But after her mother, unsettled by growing political unrest, leaves for medical treatment in India, the civil war intensifies, changing young Enjeela’s life forever. Amid the rumble of invading Soviet tanks, Enjeela and her family are thrust into chaos and fear when it becomes clear that her mother will not be coming home.Thus begins an epic, reckless, and terrifying five-year journey of escape for Enjeela, her siblings, and their father to reconnect with her mother. In navigating the dangers ahead of them, and in looking back at the wilderness of her homeland, Enjeela discovers the spiritual and physical strength to find hope in the most desperate of circumstances.A heart-stopping memoir of a girl shaken by the brutalities of war and empowered by the will to survive, The Broken Circle brilliantly illustrates that family is not defined by the borders of a country but by the bonds of the heart.