Your life, your thoughts, your diseases, and your health are all the function of cells.But what do you really know about what goes on inside you?The last time most people thought about cells in any detail was probably in high school or a college general biology class. But the field of cell biology has advanced incredibly rapidly in recent decades, and a great deal of what we may have learned in high school and college is no longer accurate or particularly relevant.The Cell: Inside the Microscopic World that Determines Our Health, Our Consciousness, and Our Future is a fascinating story of the incredible complexity and dynamism inside the cell and of the fantastic advancements in our understanding of this microscopic world.Dr. Joshua Z. Rappoport is at the forefront of this field, and he will take you on a journey to discover:A deeper understanding of how cells work and the basic nature of life on earth.Fascinating histories of some of the key discoveries from the seventeenth century to the last decade and provocative thoughts on the current state of academic research.The knowledge required to better understand the new developments that are announced almost weekly in science and health care, such as cancer, cellular therapies, and the potential promise of stem cells.The ability to make better decisions about health and to debunk the misinformation that comes in daily via media.Using the latest scientific research, The Cell illustrates the diversity of cell biology and what it all means for your everyday life.

    James Cleaves II seek to answer the most crucial question in science: How did life begin? They trace the trials and triumphs of the iconoclastic scientists who have sought to solve the mystery, from Darwin’s theory of evolution to Crick and Watson’s unveiling of DNA. This fascinating exploration not only examines the origin-of-life question, but also interrogates the very nature of scientific discovery and objectivity.

    Nobody is perfect. And that includes five of the greatest scientists in history—Charles Darwin, William Thomson (Lord Kelvin), Linus Pauling, Fred Hoyle, and Albert Einstein. But the mistakes that these great luminaries made helped advance science. Indeed, as Mario Livio explains, science thrives on error, advancing when erroneous ideas are disproven.As a young scientist, Einstein tried to conceive of a way to describe the evolution of the universe at large, based on General Relativity—his theory of space, time, and gravity. Unfortunately he fell victim to a misguided notion of aesthetic simplicity. Fred Hoyle was an eminent astrophysicist who ridiculed an emerging theory about the origin of the universe that he dismissively called “The Big Bang.” The name stuck, but Hoyle was dead wrong in his opposition.They, along with Darwin (a blunder in his theory of Natural Selection), Kelvin (a blunder in his calculation of the age of the earth), and Pauling (a blunder in his model for the structure of the DNA molecule), were brilliant men and fascinating human beings. Their blunders were a necessary part of the scientific process. Collectively they helped to dramatically further our knowledge of the evolution of life, the Earth, and the universe.

    The majority view is that life began with replicating molecules, the precursors of modern genes. The minority belief is that random populations of molecules evolved metabolic activities before exact replication existed and that natural selection drove the evolution of cells toward greater complexity for a long time without the benefit of genes. Dyson analyzes both of these theories with reference to recent important discoveries by geologists and chemists, aiming to stimulate new experiments that could help decide which theory is correct. This second edition covers the impact revolutionary discoveries such as the existence of ribozymes, enzymes made of RNA; the likelihood that many of the most ancient creatures are thermophilic, living in hot environments; and evidence of life in the most ancient of all terrestrial rocks in Greenland have had on our ideas about how life began. It is a clearly written, fascinating book that will appeal to anyone interested in the origins of life.

    And yet for many years it was equally baffling for scientists themselves. Manjit Kumar gives a dramatic and superbly-written history of this fundamental scientific revolution, and the divisive debate at its heart.For 60 years most physicists believed that quantum theory denied the very existence of reality itself. Yet Kumar shows how the golden age of physics ignited the greatest intellectual debate of the twentieth century.Quantum sets the science in the context of the great upheavals of the modern age. In 1925 the quantum pioneers nearly all hailed from upper-middle-class academic families; most were German; and their average age was 24. But it was their irrational, romantic spirit, formed in reaction to the mechanised slaughter of the First World War that inspired their will to test science to its limits.The essential read for anyone fascinated by this complex and thrilling story and by the band of young men at its heart.

    

    Science has seen its fair share of punch-ups over the years, but one debate, in the field of biology, has become notorious for its intensity. Over the last twenty years, Richard Dawkins and Stephen Jay Gould have engaged in a savage battle over evolution, which continues to rage even after Gould's death in 2002. Kim Sterelny moves beyond caricature to expose the real differences between the conceptions of evolution of these two leading scientists. He shows that the conflict extends beyond evolution to their very beliefs in science itself; and, in Gould?s case, to domains in which science plays no role at all.

    World History

    Here and there, we can supplement these meager scraps by the use of biochemical markers or geochemical signatures that add useful information, but, even with such additional help, our reconstructions and our models of descent are often tentative. For the fossil record is, as we have seen, as biased as it is incomplete. But fragmentary, selective, and biased though it is, the fossil record, with all its imperfections, is still a treasure. Though whole chapters are missing, many pages lost, and the earliest pages so damaged as to be, as yet, virtually unreadable, this--the greatest biography of all--is one in whose closing pages we find ourselves.--from OriginsIn Origins, Frank H. T. Rhodes explores the origin and evolution of living things, the changing environments in which they have developed, and the challenges we now face on an increasingly crowded and polluted planet. Rhodes argues that the future well-being of our burgeoning population depends in no small part on our understanding of life's past, its long and slow development, and its intricate interdependencies.Rhodes's accessible and extensively illustrated treatment of the origins narrative describes the nature of the search for prehistoric life, the significance of geologic time, the origin of life, the emergence and spread of flora and fauna, the evolution of primates, and the emergence of modern humans.

    He decried the internment of Japanese-Americans in World War Two, agitated against nuclear weapons, promoted vitamin C as a cure for the common cold and researched the idea of DNA.

    Here are Einstein, Fleming, Bohr, McClintock, Paul ing, Watson and Crick, Heisenberg and many others. With remarkable insight, Lightman charts the intellectual and emotional landscape of the time, portrays the human drama of discovery, and explains the significance and impact of the work. Finally he includes a fascinating and unique guided tour through the original papers in which the discoveries were revealed. Here is science writing at its best–beautiful, lyrical and completely accessible. It brings the process of discovery to life before our very eyes.

    Using illustrations and examples from science fiction pulp magazines and comic books, The Amazing Story of Quantum Mechanics explains the fundamental principles of quantum mechanics that underlie the world we live in.Watch a Video

    xn + yn = zn, where n represents 3, 4, 5, ...no solution"I have discovered a truly marvelous demonstration of this proposition which this margin is too narrow to contain."With these words, the seventeenth-century French mathematician Pierre de Fermat threw down the gauntlet to future generations.  What came to be known as Fermat's Last Theorem looked simple; proving it, however, became the Holy Grail of mathematics, baffling its finest minds for more than 350 years.  In Fermat's Enigma--based on the author's award-winning documentary film, which aired on PBS's "Nova"--Simon Singh tells the astonishingly entertaining story of the pursuit of that grail, and the lives that were devoted to, sacrificed for, and saved by it.  Here is a mesmerizing tale of heartbreak and mastery that will forever change your feelings about mathematics.

    He proposes that we look at evolution as a battle between genes instead of between whole organisms. We can then view changes in phenotypes—the end products of genes, like eye color or leaf shape, which are usually considered to increase the fitness of an individual—as serving the evolutionary interests of genes.Dawkins makes a convincing case that considering one’s body, personality, and environment as a field of combat in a kind of “arms race” between genes fighting to express themselves on a strand of DNA can clarify and extend the idea of survival of the fittest. This influential and controversial book illuminates the complex world of genetics in an engaging, lively manner.

    It is the repository of our deepest religious andartistic impulses, the organ whose steady functioning is understood, both literally and symbolically, asthe very life force itself. The Sublime Engine explores the profound sense of awe every person feels when they ponder the miracle encased within the ribs. In this lyrical history, a critically acclaimed novelist and a leading cardiologist—who happen to be brothers— draw upon history, science, religion, popular culture, and literature to illuminate all of the heart’s physical and figurative chambers. Divided into six sections, The Sublime Engine traces the heart’s sway over the human imagination from the time of the Egyptians and ancient Greece, through the Middle Ages and Renaissance, up to the modern era and beyond. More than just a work of scientific or cultural history, it is a biography of the single most important symbol of our humanity. Erudite, witty, and unexpected, The Sublime Engine makes the heart leap off the page.