even the most devout canine advocates may come away touched to the core." -Adrea Gibbs, Life With Dogs Meet Shadow. He's a little older and slower than he used to be, but he has a heart of gold, and he's a good dog. People always tell him so. He'll never hesitate to give your face a good licking, and there's no one he loves more than his human, Brian. Brian got a new puppy for Christmas though, leading him to abandon Shadow at the shelter he came from eleven years earlier. Shadow is devastated. Worse, the clock is winding down, even as a caring shelter worker helps him heal from the betrayal. Each day brings him closer to being euthanized in order to make more room at the shelter, and his fate rests in the hands of the very species that betrayed him—humans. Shadow’s story is the story of countless real-life dogs that end up in shelters every year. In an effort to help save them, 20% of royalties will go to Love & Second Chances all-breed dog rescue.

    While maintaining the hallmark features of previous editions, the Fourth Edition has been completely updated. It includes new Key Concepts at the beginning of each chapter and annotated further reading at the conclusion of each chapter, to help readers navigate the wealth of information in this subject.The text has been restructured so genomic technologies are integrated throughout, and next generation sequencing is included. Genetic testing, screening, approaches to therapy, personalized medicine, and disease models have been brought together in one section. Coverage of cell biology including stem cells and cell therapy, studying gene function and structure, comparative genomics, model organisms, noncoding RNAs and their functions, and epigenetics have all been expanded.

     A powerful, heart-warming and inspiring memoir from the UK's most famous and beloved vet, Professor Noel Fitzpatrick - star of the Channel 4 series The Supervet. Growing up on the family farm in Ballyfin, Ireland, Noel's childhood was spent tending to the cattle and sheep, the hay and silage, the tractors and land, his beloved sheepdog Pirate providing solace from the bullies that plagued him at school. It was this bond with Pirate, and a fateful night spent desperately trying to save a newborn lamb, that inspired Noel to enter the world of veterinary science - and set him on the path to becoming The Supervet.Now, in this long-awaited memoir, Noel recounts this often-surprising journey that sees him leaving behind a farm animal practice in rural Ireland to set up Fitzpatrick Referrals in Surrey, one of the most advanced small animal specialist centres in the world. We meet the animals that paved the way, from calving cows and corralling bullocks to talkative parrots and bionic cats and dogs. Noel has listened to the many lessons that the animals in his care have taught him, and especially the times he has shared with his beloved Keira, the scruffy Border Terrier who has been by Noel's side as he's dealt with the unbelievable highs and crushing lows of his extraordinary career. As heart-warming and life-affirming as the TV show with which he made his name, Listening to the Animals is a story of love, hope and compassion, and about rejoicing in the bond between humans and animals that makes us the very best we can be.

    Believing in a fairy tale world where dogs possess the same moral consciousness and a sense of altruism as attributed to humans has led to consequences that include a drastic increase in leash laws, dogs being outlawed in a rising number of city and national parks, some breeds being banned in several states, an alarming escalation of aggression to humans, a rising cost in homeowner and business insurance, and a record number of clinically maladaptive dogs. This book is not a dog obedience book. Rather, it is about developing a deep understanding of the authors of your dog's behavior; nature and the wolf. For all that man has done to carve the wolf from the wild to create a biological doll, today's dog is still a wolf at heart and the accompanying instincts borne from such ancestry defines how the dog approaches its world. In this book, you will come to know the wolf in your dog and the tools that nature gave it to survive and coexist in both the mountains and in your home. You will learn how activating and deactivating the natural wolf impulses and mechanisms in your dog will lead to the harmonious existence and the control you always dreamed of. Most of all, you will come to embrace the wild in your dog and the grace and the peace that is breathed into its acceptance.

    Judy saved Frank’s life many times over and raised the morale of all the men in the camp.Extracted from the bestselling title The Dog That Saved My Life, this short story tells the tale of a dog like no other, a dog who was awarded an animals’ Victoria Cross for her bravery and devotion.

    Then again, he never imagined that a chance meeting with a lost and dying dog named Shandy would change his life forever. Step into the small Irish village of Galbally, where the unwitting Spencer stumbles headfirst into a parallel world that will test his will, sanity, and even physical well-being. Time and promise are running out. Will unnatural forces and events scare Spencer away before he can connect again with the mysterious dog? Will he find his way forward before Shandy meets her inevitable fate? Or will suspicious locals and a nefarious Dublin innkeeper force Spencer from the village before he completes his life-altering mission? Follow Spencer as he races to save a little Irish dog named Shandy. If he only realized that it is Shandy who is trying to save him...

    BOOK OF THE BITCH: A Complete Guide to Understanding and Caring for Bitches

    Unlocking the secrets of our genomes opens the door to understanding why we are the way we are and potentially fixing what ails us, from cancer and diabetes to obesity and male pattern baldness. But what exactly will happen to this information? Will it be a boon or just another marketing tool?Here Is a Human Being is the first in-depth look at personal genomics—its larger-than-life research subjects; its entrepreneurs and do-it-yourselfers; its technology developers; and the bewildered physicians and regulators who must negotiate with it—and what it means to be a “public genome” in a world where privacy is already under siege.

    Book by Donaldson, Jean

    In biology labs across the world, fruit flies are turning up answers to some of the basic questions of life. It's business as usual for the fly, which for generations has been defining biology's major landmarks. From genetics to development, behavior to aging, and evolution to the origin of species, the fruit fly has been a key player in some of the twentieth century's greatest biological discoveries.Techniques to pinpoint genes that play a role in human disease depend on genetic mapmaking principles first established with the fly. It was experiments on fruit flies that opened our eyes to the dangers of radiation to human health. In fact, everything from gene therapy to cloning to the Human Genome Project is built on the foundation of fruit fly research. Despite its many achievements, the fruit fly remains an unsung hero in the history of science. At last, here is a book that gives the fly its long overdue credit.In a highly original, witty, and irreverent style, Martin Brookes takes us through successive stages in the life cycle of the fly, each illustrating an important concept in biology. Some, such as the fundamentals of heredity, are well established; others, such as sexual warfare, learning, and memory, are still in their infancy. But whether flies are getting high on crack cocaine, enjoying the pleasures and pains of a boozy night out, being trained by punishment and reward, or struggling with insomnia, this book provides a glimpse of how one short life has informed almost every aspect of human existence. The result is a broad introduction to biology with insights into the practical realities of science.Often dismissed as irrelevant outside academic circles, the fruit fly, through this distinctive biography, will come to be recognized for what it really is: an icon of twentieth-century science and a window on our own biological world.

    Julie Klam was thirty, single, and working as a part-time clerk in an insurance company, wondering if she would ever meet the man she could spend the rest of her life with. And then it happened. She met the irresistible Otto, her first in a long line of Boston terriers, and fell instantly in love.You Had Me at Woof is the often hilarious and always sincere story of how one woman discovered life's most important lessons from her relationships with her canine companions. From Otto, Julie realized what it might feel like to find "the one." She learned to share her home, her heart, and her limited resources with another, and she found an authentic friend in the process. But that was just the beginning. Over the years her brood has grown to one husband, one daughter, and several Boston terriers. And although she had much to learn about how to care for them-walks at 2 a.m., vet visits, behavior problems-she was surprised and delighted to find that her dogs had more wisdom to convey to her than she had ever dreamed. And caring for them has made her a better person-and completely and utterly opened her heart. Riotously funny and unexpectedly poignant, You Had Me at Woof recounts the hidden surprises, pleasures, and revelations of letting any mutt, beagle, terrier, or bulldog go charging through your world.

     Animal lovers and sports fans were shocked when the story broke about NFL player Michael Vick's brutal dog fighting operation. But what became of the dozens of dogs who survived? As acclaimed writer Jim Gorant discovered, their story is the truly newsworthy aspect of this case. Expanding on Gorant's Sports Illustrated cover story, The Lost Dogs traces the effort to bring Vick to justice and turns the spotlight on these infamous pit bulls, which were saved from euthanasia by an outpouring of public appeals coupled with a court order that Vick pay nearly a million dollars in "restitution" to the dogs. As an ASPCA-led team evaluated each one, they found a few hardened fighters, but many more lovable, friendly creatures desperate for compassion. In The Lost Dogs, we meet these amazing animals, a number of which are now living in loving homes, while some even work in therapy programs: Johnny Justice participates in Paws for Tales, which lets kids get comfortable with reading aloud by reading to dogs; Leo spends three hours a week with cancer patients and troubled teens. At the heart of the stories are the rescue workers who transformed the pups from victims of animal cruelty into healing caregivers themselves, unleashing priceless hope.Includes an 8-page photo insert.Watch a video

    Claire Arrowsmith strongly suggests that such challenges help build a strong bond between a dog and its owner. She examines the accepted evidence of the importance of mental stimulation and why it's important to use only reward-based teaching methods. She also explains how to use hand signals and incorporate mental challenges and learning into everyday activities.Icons for each game indicate whether it is interactive, solo or group, where it can be played, the level of difficulty and whether any props or toys are used. Some of these great games are:Puppy PlayHide and SeekCarry ItEgg and Spoon RaceMini Agility CourseNature's Obstacle CourseFind the TreatRoll Over, Play Dead and other performance tricksWith straightforward text and full-color photographs, Brain Games for Dogs is a valuable guide to important elements for successful and fun dog training.

    For decades after the structure of DNA was identified, scientists focused purely on genes, the regions of the genome that contain codes for the production of proteins. Other regions - 98% of the human genome - were dismissed as 'junk'. But in recent years researchers have discovered that variations in this 'junk' DNA underlie many previously intractable diseases, and they can now generate new approaches to tackling them. Nessa Carey explores, for the first time for a general audience, the incredible story behind a controversy that has generated unusually vituperative public exchanges between scientists. She shows how junk DNA plays an important role in areas as diverse as genetic diseases, viral infections, sex determination in mammals, human biological complexity, disease treatments, even evolution itself - and reveals how we are only now truly unlocking its secrets, more than half a century after Crick and Watson won their Nobel prize for the discovery of the structure of DNA in 1962.

    The species that survive will be the ones that are most compatible with us: the weedy species--from mosquitoes to coyotes--that thrive in continually disturbed human-dominated environments. The End of the Wild is a wake-up call. Marshaling evidence from the last ten years of research on the environment, Stephen Meyer argues that nothing--not national or international laws, global bioreserves, local sustainability schemes, or wildlands--will change the course that has been set. Like it or not, we can no longer talk about conserving nature, only managing what is left. The race to save biodiversity is over.But that doesn't mean our work is over. The End of the Wild is also a call to action. Without intervention, the surviving ecosystems we depend on for a range of services--including water purification and flood and storm damage contro--could fail and the global spread of invasive species (pests, parasites, and disease-causing weedy species) could explode. If humanity is to survive, Meyer argues, we have no choice but to try to manage the fine details. We must move away from the current haphazard strategy of protecting species in isolation and create trans-regional meta-reserves, designed to protect ecosystem functions rather than species-specific habitats.