The latest version is far superior, both in content and presentation, to previous versions. I give it my highest recommendation."--"Doody's Review Service"From the authors of "Basic and Clinical Pharmacology," the leading pharmacology textbook, here is the newest edition of the best review book available for medical pharmacology course exams and board examinations. This skill-building guide comes with over 1000 review questions and answers -- far more than most other pharmacology reviews -- and a chapter-based approach that facilitates use with course notes or larger texts. Features: A new full-color presentation Organized to reflect course syllabi, focusing on the clinical use and pharmacology of drug categories, rather than individual drugs Two complete practice exams A valuable appendix of test-taking strategies Chapters that include valuable learning aids such as: --Short discussion of the major concepts that underlie basic principles or drug groups--Explanatory figures and tables--Review questions followed by answers and explanations--Drug Trees in drug-oriented chapters that visually organize drug groups--A list of high-yield terms and definitions you need to know Skill Keeper questions that prompt you to review previous material to understand links between related topics A checklist of tasks you should be able to do, once you have finished the chapter Summary Tables that list the important drugs and include key information about their mechanisms of action, effects, clinical uses, pharmacokinetics, drug interactions, and toxicities

    Building upon that record and the recollections of other F-4G Wild Weasel aircrew, the authors show a slice of what life and war was like during that time. The pawns in the game, the ones that had to actually do the fighting and dying were the hundreds of thousands of men and women who left their homes and families to live for seemingly endless months in the vast, trackless desert while the world stage-play unfolded. To them, the war was deeply personal. At times, the war was scary; at other times, it was funny as hell. Usually, if you survive the former, it turns into the latter.

    From 5K to ultramarathon, a power meter can make you faster—but only if you know how to use it. Just viewing your numbers is not enough; you can only become a faster, stronger, more efficient runner when you know what your key numbers mean for your workouts, races, and your season-long training. In Run with Power, TrainingBible coach Jim Vance offers the comprehensive guide you need to find the speed you want.Run with Power demystifies the data and vocabulary so you can find and understand your most important numbers. You’ll set your Running Power Zones so you can begin training using 8 power-based training plans for 5K, 10K, half-marathon, and marathon. Vance shows you how you can compare wattage, heart rate, pace, and perceived exertion to gain the maximum insight into your performances, how you respond to training, and how you can train more effectively. Run with Power will revolutionize how you train and race. Armed with Vance’s guidance, you can train more specifically for races, smooth your running technique, accurately measure your fitness, predict a fitness plateau, monitor injuries, know exactly how hard you’re training, get more fitness from every workout, recover fully, perfect your tapers, warm up without wasting energy, pace your race on any terrain, know when to open the throttle, and create an unprecedented picture of yourself as an athlete.If you’re just glancing at the number on your wrist or computer monitor, you’ve got a lot more speed potential. Knowledge is power and understanding your power numbers can open the gate to new methods and new PRs. Run with Power introduces the use of power meters to the sport of running and will show you how to break through to all-new levels of performance.Key concepts explored in Run with Power: 3/9 Test, 30-minute Time Trial Test, Running Functional Threshold Power (rFTPw), Running Functional Threshold Pace (rFTPa), Averaged and Normalized Power (NP), Intensity Factor (IF), Peak Power, Variability Index, Efficiency Index (EI), speed per watt, Vance’s Power Zones for Running, Training Stress Score (TSS), and Periodization with Power. Includes 6 testing methods and 8 power-based training schedules and workouts for 5K, 10K, half-marathon, and marathon.

    In 1919, Spanish flu killed over 50 million people, more than died in both world wars combined. In 1950, an estimated 50 million people caught smallpox worldwide, of whom 10 million died. In 1980, before measles vaccine was widely used, an estimated 2.6 million children died of measles every year. Today we are hostage to a new pandemic disease -the seemingly unstoppable COVID-19.Less than 100 years ago, losing a child to an infection like diphtheria or polio was a dreaded but almost inevitable sorrow faced by all parents, from the richest to the poorest. Today, these killer diseases are almost never seen in industrialised countries, thanks to the development of vaccines. Immunisation has given modern parents peace of mind their ancestors could not imagine.The history of vaccination is rich with trial, error, sabotage and success. It encompasses the tragedy of lives lost, the drama of competition and discovery, the culpability of botched testing, and the triumph of effective, lifelong immunity. Yet with the eradication in the first world of some of humanity's deadliest foes, complacency in some quarters has set in. COVID-19 has us again racing for a vaccine. The story of past achievements and failures helps us keep the race - and the hope - in perspective.This is a book for everyone who wants to understand our past - and cares about our future.PRAISE'Anyone who has doubts about the life-saving miracle of vaccination should read this' Steven Carroll, Sydney Morning Herald'An entertaining and engaging work that is sure to delight general readers' Australian Book Review'The ideal handbook for pregnant women, parents, travellers, childcare and aged-care workers, GPs and anyone with an interest in public health' The Australian'Isaacs explores the understanding of immunity as it develops from the fifth century BC to the present day and thrills us with the progressive successes of each of the 14 vaccines which a child routinely receives today ... The work is authoritative, beguiling, amusing, instructive and inspirational. It deserves a wide readership, including infectious disease experts, other health professionals and, most assuredly, a diversity of lay people' Sir Gustav Nossal, immunologist and director of The Walter and Eliza Institute of Medical Research, Melbourne, 1965-1996'A rollicking story of human endeavour, error, misinformation, success and failure ... and more than a glimpse of why we need to continue to research, evaluate, educate and fund vaccines to prevent disease' Fiona Stanley, Distinguished Research Professor, University of Western Australia'Effortlessly accessible, Defeating the Ministers of Death brilliantly reveals the people behind the most important public health intervention in history' Professor Andrew J Pollard, Department of Paediatrics, University of Oxford'This book is an unflinching look at the triumphs and inevitable tragedies in the war against infectious diseases. Nonfiction is at its best when it reads like fiction. And David Isaacs has written a page turner' Paul A. Offit, MD, author of Bad Advice: Or Why Celebrities, Politicians, and Activists Aren't Your Best Source of Health Information

    Diligently researching how to restore his quality of life, she discovered Vet-Stem, a service that provides cutting-edge regeneration therapy for pets, using stem cells harvested from animals' own tissue. Just hours after receiving IV and intra-joint injections, Sam began aging backward--which left Julia wondering why this simple, effective treatment was not available for humans.            Julia suffered from chronic inflammatory bowel disease, and after witnessing Sam's astonishing recovery, she set out on a curious quest: to be treated like a dog by a doctor as competent as her vet! After a four-year wait, Julia became the first American to be successfully cured of a perirectal fistula with stem cells derived from her own fat. With this amazing true story of how a pack of shelter dogs she rescued from death row came to save her life, Julia hopes to inspire and inform readers about exciting healthcare options available to them and their cherished animal companions.

    Drawing on sources as diverse as monastic manuscripts and dendrochronological studies (which measure growth rings in trees), historian Robert S. Gottfried demonstrates how a bacillus transmitted by rat fleas brought on an ecological reign of terror—killing one European in three, wiping out entire villages and towns, and rocking the foundation of medieval society and civilization.

    The book has the hallmark features for which Lippincott's Illustrated Reviews volumes are so popular: an outline format, over 600 full-color illustrations, end-of-chapter summaries, review questions, plus an entire section of clinical case studies with full-color illustrations. This edition's medical/clinical focus has been sharpened to provide a high-yield review. Five additional case studies have been included, bringing the total to nineteen. Review questions have been reformatted to comply with USMLE Step 1 style, with clinical vignettes.

    By the middle of the twentieth century, it was killing millions and, as with the Black Death centuries before, physicians stood helpless. Visionaries, though, had begun to make strides earlier. On September 7, 1895, Ludwig Rehn successfully sutured the heart of a living man with a knife wound to the chest for the first time. In 1929, Dr. Werner Forssman inserted a cardiac catheter in his own arm and forced the X-ray technician on duty to take a photo as he successfully threaded it down the vein into his own heart . . . and lived. And on June 6, 1944 D-Day another momentous event occurred far from the Normandy beaches: Dr. Dwight Harken sutured the shrapnel-injured heart of a young soldier and saved his life, and thus the term "cardiac surgeon" was born. In "The Heart Healers," James Forrester, MD, tells the story of these rebels and the risks they took with their own lives and the lives of others to heal the most elemental of human organs: the heart. The result is a compelling chronicle of a disease and its cure, a disease that is still with us, but one that is slowly being worn away by the "Heart Healers."

    

    David Horowitz’s classic Why Israel is the Victim, updated by the author, sets the record straight about the basic truths of the Middle East conflict. In addition to restoring the authentic history of the region – a history of obsessive aggression first by Arab countries determined to physically annihilate the Jewish State and later by terror groups determined to destroy its will to survive and right to exist—this booklet brings the story up to date by showing the systematic way in which Hamas and Hezbollah, under Iran’s direction, have subverted peace in the Middle East. As Shillman Fellow Daniel Greenfield notes in his insightful introduction, this pamphlet “tells us why we should reject the “Blame Israel First” narrative that has so thoroughly saturated the mainstream media… It confronts the myth of Palestinian victimhood… and it delivers a rousing restatement of the true history of the hate that led us to all this.” America should be Israel’s protector. Instead, as David Horowitz notes, under the leadership of Barack Obama, it has become its prosecutor.

    Then came the water, and for five days, the country’s oldest hospital was under siege. The never-before-told story of the heroic doctors, nurses — and patients — who fought to survive Hurricane Katrina at Charity Hospital in New Orleans.The story traces a remarkable five-day transformation of an infirm institution, caught in a sea of death and indifference, into an island of care and tenderness.

    For the past few decades, technology has been touted as the cure for all of healthcare's ills.But medicine stubbornly resisted computerization - until now. Over the past five years, thanks largely to billions of dollars in federal incentives, healthcare has finally gone digital.Yet once clinicians started using computers to actually deliver care, it dawned on them that something was deeply wrong. Why were doctors no longer making eye contact with their patients? How could one of America's leading hospitals give a teenager a 39-fold overdose of a common antibiotic, despite a state-of-the-art computerized prescribing system? How could a recruiting ad for physicians tout the absence of an electronic medical record as a major selling point?Logically enough, we've pinned the problems on clunky software, flawed implementations, absurd regulations, and bad karma. It was all of those things, but it was also something far more complicated. And far more interesting . . .Written with a rare combination of compelling stories and hard-hitting analysis by one of the nation's most thoughtful physicians, The Digital Doctor examines healthcare at the dawn of its computer age. It tackles the hard questions, from how technology is changing care at the bedside to whether government intervention has been useful or destructive. And it does so with clarity, insight, humor, and compassion. Ultimately, it is a hopeful story."We need to recognize that computers in healthcare don't simply replace my doctor's scrawl with Helvetica 12," writes the author Dr. Robert Wachter. "Instead, they transform the work, the people who do it, and their relationships with each other and with patients. . . . Sure, we should have thought of this sooner. But it's not too late to get it right."This riveting book offers the prescription for getting it right, making it essential reading for everyone - patient and provider alike - who cares about our healthcare system.

    and a PhD.  While he was a student, and later during his surgical internship at the Johns Hopkins Hospital, he began the series of animal experiments that led eventually to the world’s first transplantation of the human liver in 1963.Throughout his career, first at the University of Colorado and then at the University of Pittsburgh, he has aroused both worldwide admiration and controversy.  His technical innovations and medical genius have revolutionized the field, but Starzl has not hesitated to address the moral and ethical issues raised by transplantation.  In this book he clearly states his position on many hotly debated issues including brain death, randomized trials for experimental drugs, the costs of transplant operations, and the system for selecting organ recipients from among scores of desperately ill patients.There are many heroes in the story of transplantation, and many “puzzle people,” the patients who, as one journalist suggested, might one day be made entirely of various transplanted parts.  They are old and young, obscure and world famous.  Some have been taken into the hearts of America, like Stormie Jones, the brave and beautiful child from Texas.  Every patient who receives someone else’s organ - and Starzl remembers each one - is a puzzle.  “It was not just the acquisition of a new part,” he writes.  “The rest of the body had to change in many ways before the gift could be accepted.  It was necessary for the mind to see the world in a different way.”  The surgeons and physicians who pioneered transplantation were also changed: they too became puzzle people.  “Some were corroded or destroyed by the experience, some were sublimated, and none remained the same.”

    

     With all that has been said about Dodge City no true account of conditions as they were in the early days was accessible until publication of Robert Wright's 1911 book "Dodge City, the Cowboy Capital." The author was especially well qualified to write a history of the "wicked city of the plains" since he had lived on the frontier for many years previous to the founding of the city and lived in the city from its opening. He had all the experience gleaned as a plainsman, explorer, scout, trader and as mayor of the town. His is a most interesting narrative of early days, as well as a very valuable contribution to western history. Prior to founding Dodge City in 1868, at 16 years old Wright came West to Missouri. In 1859 he made the first of six overland trips across the plains to Denver. He was later appointed post trader at Fort Dodge in 1867, when Kiowa, Comanche, Cheyenne, Arapahoe, and Prairie Apache abounded there. Wright was acquainted with old-school Western sheriff and gunfighter Bat Masterson, of whom he said, "Bat is a gentleman by instinct. He is a man of pleasant manners, good address and mild disposition, until aroused, and then, for God's sake, look out! "Bat was a most loyal man to his friends. If anyone did him a favor, he never forgot it. I believe that if one of his friends was confined in jail and there was the least doubt of his innocence, he would take a crow-bar and 'jimmy' and dig him out, at the dead hour of midnight; and, if there were determined men guarding him, he would take these desperate chances...." Wright describes a typical day in Dodge: "Someone ran by my store at full speed, crying out, 'Our marshal is being murdered in the dance hall!' I, with several others, quickly ran to the dance hall and burst in the door. The house was so dense with smoke from the pistols a person could hardly see, but Ed Masterson had corralled a lot in one corner of the hall, with his sixshooter in his left hand, holding them there until assistance could reach him...." Wright also describes one hair-raising encounter he witnessed from a roof on his ranch: "The savages circled around the poor Mexican again and again; charged him from the front and rear and on both sides. Presently the poor fellow's horse went down, and he lay behind it for awhile. Then he cut the girth, took off the saddle, and started for the river, running at every possible chance, using the saddle as a shield, stopping to show fight only when the savages pressed him too closely