The police are stumped. Halloween is coming, with an ancient evil on the horizon. The vampires are the good guys. This is not your ordinary fall weekend in Charlotte, NC. Vampire private detectives Jimmy Black and Greg Knightwood have been hired to keep a young client from being cursed for all eternity, but end up in a bigger mess than they ever imagined. Suddenly trapped in the middle of a serial kidnapping case, Jimmy and Greg uncover a plot to bring forth an ancient evil into the world, and enlist the help of a police detective, a priest, a witch, a fallen angel and strip club proprietor to save the world. This unlikely band of heroes battles zombies, witches, neuroses and sunburn while cracking jokes and looking for the perfect bag of O-negative.