We take for granted that we can remember, feel emotion, navigate, empathize, and understand the world around us, but how would our lives change if these abilities were dramatically enhanced--or disappeared overnight?Helen Thomson has spent years traveling the world, tracking down incredibly rare brain disorders. In Unthinkable she tells the stories of nine extraordinary people she encountered along the way. From the man who thinks he's a tiger to the doctor who feels the pain of others just by looking at them to a woman who hears music that’s not there, their experiences illustrate how the brain can shape our lives in unexpected and, in some cases, brilliant and alarming ways.Story by remarkable story, Unthinkable takes us on an unforgettable journey through the human brain. Discover how to forge memories that never disappear, how to grow an alien limb, and how to make better decisions. Learn how to hallucinate and how to make yourself happier in a split second. Find out how to avoid getting lost, how to see more of your reality, even how exactly you can confirm you are alive. Think the unthinkable.

    David Schneider’s The Invention of Surgery is an in-depth biography of the practice that has leapt forward over the centuries from the dangerous guesswork of ancient Greek physicians through the world-changing “implant revolution” of the twentieth century.The Invention of Surgery explains this dramatic progress and highlights the personalities of the discipline's most dynamic historical figures. It links together the lives of the pioneering scientists who first understood what causes disease, how organs become infected or cancerous, and how surgery could powerfully intercede in people’s lives, and then shows how the rise of surgery intersected with many of the greatest medical breakthroughs of the last century, including the evolution of medical education, the transformation of the hospital from a place of dying to a habitation of healing, the development of antibiotics, and the rise of transistors and polymer science.And as Schneider argues, surgery has not finished transforming; new technologies are constantly reinventing both the practice of surgery and the nature of the objects we are permanently implanting in our bodies. Schneider considers these latest developments, asking “What’s next?” and analyzing how our conception of surgery has changed alongside our evolving ideas of medicine, technology, and our bodies.

    Drawing from Scientific American's "Fact or Fiction" and "Strange But True" columns, we've selected fifty-eight of the most surprising, fascinating, useful, and just plain wacky topics confronted by our writers over the years.

    When Theodore Roosevelt became president in 1901, his beautiful and flamboyant daughter was transformed into "Princess Alice," arguably the century's first global celebrity. Thirty-two years later, her first cousin Eleanor moved into the White House as First Lady. Born eight months and twenty blocks apart from each other in New York City, Eleanor and Alice spent a large part of their childhoods together and were far more alike than most historians acknowledge. But their politics and temperaments couldn't have been more distinct. Do-gooder Eleanor was committed to social justice but hated the limelight; acid-tongued Alice, who became the wife of philandering Republican congressman Nicholas Longworth, was an opponent of big government who gained notoriety for her cutting remarks (she famously quipped that dour President Coolidge “looked like he was weaned on a pickle”). While Eleanor revolutionized the role of First Lady with her outspoken passion for human rights, Alice made the most of her insider connections to influence politics, including doing as much to defeat the League of Nations as anyone in elective office.The cousins themselves liked to play up their oil-and-water relationship. “When I think of Frank and Eleanor in the White House I could grind my teeth to powder and blow them out my nose,” Alice once said. In the 1930s they even wrote opposing syndicated newspaper columns and embarked on competing nationwide speaking tours. Blood may be thicker than water, but when the family business is politics, winning trumps everything.Vivid, intimate, and stylishly written, Hissing Cousins finally sets this relationship center stage, revealing the contentious bond between two political trailblazers who short-circuited the rules of gender and power, each in her own way.

    microbe.” —The Wall Street Journal   Did the Black Death destroy medieval Europe? Did cholera pave the way for modern Manhattan? Did yellow fever help end the slave trade? Remarkably, the answer to all of these questions is yes. Time and again, diseases have impacted the course of human history in surprisingly powerful ways. From influenza to smallpox, from tuberculosis to yellow fever, Bryn Barnard describes the symptoms and paths of the world’s worst diseases—and how the epidemics they spawned have changed history forever.   Filled with fascinating, often gory details about disease and history, Outbreak! is a wonderful combination of science and history.

    There have been other books on Dr Morell's cocktail of treatments for Hitler and Goering's reliance on drugs, but Ohler's book is the first to show how the entire Nazi regime was permeated with drugs - cocaine, heroin, morphine and methamphetamines, the last of these crucial to troops' resilience and partly explaining German victory in 1940. Ohler is explicit that drugs cannot explain Third Reich ideology, but their promiscuous use impaired and confused decision-making, with drastic effects on Hitler and his entourage, who, as the war turned against Germany, took refuge in ever more poorly understood cocktails of stimulants. This chemical euphoria changes how we should think about the Nazi high command and its ability to understand the situation it found itself in by 1944-45. As such Blitzed will force a wider reinterpretation of several key events during the Second World War.

    His staggering fortune was fought over by his heirs after his death in 1877, sowing familial discord that would never fully heal. Though his son Billy doubled the money left by “the Commodore,” subsequent generations competed to find new and ever more extraordinary ways of spending it. By 2018, when the last Vanderbilt was forced out of The Breakers—the seventy-room summer estate in Newport, Rhode Island, that Cornelius’s grandson and namesake had built—the family would have been unrecognizable to the tycoon who started it all.Now, the Commodore’s great-great-great-grandson Anderson Cooper, joins with historian Katherine Howe to explore the story of his legendary family and their outsized influence. Cooper and Howe breathe life into the ancestors who built the family’s empire, basked in the Commodore’s wealth, hosted lavish galas, and became synonymous with unfettered American capitalism and high society. Moving from the hardscrabble wharves of old Manhattan to the lavish drawing rooms of Gilded Age Fifth Avenue, from the ornate summer palaces of Newport to the courts of Europe, and all the way to modern-day New York, Cooper and Howe wryly recount the triumphs and tragedies of an American dynasty unlike any other.Written with a unique insider’s viewpoint, this is a rollicking, quintessentially American history as remarkable as the family it so vividly captures.

    Seven months later, after joining a party of emigrants led by George Donner, they reached the Sierra Nevada Mountains as the first heavy snows of the season closed the pass ahead of them. In early December, starving and desperate, Sarah and fourteen others set out for California on snowshoes and, over the next thirty-two days, endured almost unfathomable hardships and horrors. In this gripping narrative, Daniel James Brown sheds new light on one of the most infamous events in American history. Following every painful footstep of Sarah's journey with the Donner Party, Brown produces a tale both spellbinding and richly informative.

    Not a soul on board—just blood from cabin to deck. Looted coins led to Bowery thug Albert Hicks, the ax slayer who turned his shipmates into chum.His crimes were absolutely fiendish. His execution was pure ballyhoo. It drew nearly ten thousand bloodthirsty sightseers to the city—including the enterprising showman P. T. Barnum. Refreshments were served as the most notorious and unrepentant mass murderer of the era made history as one of America’s first celebrity killers.The Pirate is part of Bloodlands, a chilling collection of short page-turning historical narratives from bestselling true-crime master Harold Schechter. Spanning a century in our nation’s murderous past, Schechter resurrects nearly forgotten tales of madmen and thrill-killers that dominated the most sensational headlines of their day.

    Unless the train is stopped, it will inevitably kill all five men. You are standing on a footbridge looking down on the unfolding disaster. However, a fat man, a stranger, is standing next to you: if you push him off the bridge, he will topple onto the line and, although he will die, his chunky body will stop the train, saving five lives. Would you kill the fat man?The question may seem bizarre. But it's one variation of a puzzle that has baffled moral philosophers for almost half a century and that more recently has come to preoccupy neuroscientists, psychologists, and other thinkers as well. In this book, David Edmonds, coauthor of the bestselling Wittgenstein's Poker, tells the riveting story of why and how philosophers have struggled with this ethical dilemma, sometimes called the trolley problem. In the process, he provides an entertaining and informative tour through the history of moral philosophy. Most people feel it's wrong to kill the fat man. But why? After all, in taking one life you could save five. As Edmonds shows, answering the question is far more complex--and important--than it first appears. In fact, how we answer it tells us a great deal about right and wrong.

    It killed more people in twenty-four months than AIDS killed in twenty-four years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision of science and epidemic disease. Magisterial in its breadth of perspective and depth of research and now revised to reflect the growing danger of the avian flu, The Great Influenza is ultimately a tale of triumph amid tragedy, which provides us with a precise and sobering model as we confront the epidemics looming on our own horizon. John M. Barry has written a new afterword for this edition that brings us up to speed on the terrible threat of the avian flu and suggest ways in which we might head off another flu pandemic.

    Judy Melinek began her training as a New York City forensic pathologist. With her husband T.J. and their toddler Daniel holding down the home front, Judy threw herself into the fascinating world of death investigation, performing autopsies, investigating death scenes, counseling grieving relatives. Working Stiff chronicles Judy's two years of training, taking readers behind the police tape of some of the most harrowing deaths in the Big Apple, including a firsthand account of the events of September 11, the subsequent anthrax bio-terrorism attack, and the disastrous crash of American Airlines flight 587.Lively, action-packed, and loaded with mordant wit, Working Stiff offers a firsthand account of daily life in one of America's most arduous professions, and the unexpected challenges of shuttling between the domains of the living and the dead. The body never lies, and through the murders, accidents, and suicides that land on her table, Dr. Melinek lays bare the truth behind the glamorized depictions of autopsy work on shows like CSI and Law and Order to reveal the secret story of the real morgue.

    In 1921, a tightly knit band of killers set out to avenge the deaths of almost one million victims of the Armenian Genocide. They were a humble bunch: an accountant, a life insurance salesman, a newspaper editor, an engineering student, and a diplomat. Together they formed one of the most effective assassination squads in history. They named their operation Nemesis, after the Greek goddess of retribution. The assassins were survivors, men defined by the massive tragedy that had devastated their people. With operatives on three continents, the Nemesis team killed six major Turkish leaders in Berlin, Constantinople, Tiflis, and Rome, only to disband and suddenly disappear. The story of this secret operation has never been fully told, until now. Eric Bogosian goes beyond simply telling the story of this cadre of Armenian assassins by setting the killings in the context of Ottoman and Armenian history, as well as showing in vivid color the era's history, rife with political fighting and massacres. Casting fresh light on one of the great crimes of the twentieth century and one of history's most remarkable acts of vengeance, Bogosian draws upon years of research and newly uncovered evidence. Operation Nemesis is the result -- both a riveting read and a profound examination of evil, revenge, and the costs of violence.

    Bonnie Henry has been called one of the most effective public health figures in the world by The New York Times. She has been called a calming voice in a sea of coronavirus madness, and our hero in national newspapers. But in the waning days of 2019, when the first rumours of a strange respiratory ailment in Wuhan, China began to trickle into her office in British Colombia, these accolades lay in a barely imaginable future.Only weeks later, the whole world would look back on the previous year with the kind of nostalgia usually reserved for the distant past. With a staggering suddenness, our livelihoods, our closest relationships, our habits and our homes had all been transformed.In a moment when half-truths threatened to drown out the truth, when recklessness all too often exposed those around us to very real danger, and when it was difficult to tell paranoia from healthy respect for an invisible threat, Dr. Henry's transparency, humility, and humanity became a beacon for millions of Canadians.And her trademark enjoinder to be kind, be calm, and be safe became words for us all to live by.Coincidentally, Dr. Henry's sister, Lynn, arrived in BC for a long-planned visit on March 12, just as the virus revealed itself as a pandemic. For the four ensuing weeks, Lynn had rare insight into the whirlwind of Bonnie's daily life, with its moments of agony and gravity as well as its occasional episodes of levity and grace. Both a global story and a family story, Be Kind, Be Calm, Be Safe combines Lynn's observations and knowledge of Bonnie's personal and professional background with Bonnie's recollections of how and why decisions were made, to tell in a vivid way the dramatic tale of the four weeks that changed all our lives.Be Kind, Be Calm, Be Safe is about communication, leadership, and public trust; about the balance between politics and policy; and, at heart, about what and who we value, as individuals and a society.The authors' advance from the publisher will be donated to charities with a focus on alleviating communities hit particularly hard by the pandemic: True North Aid with its Covid-19 response in Northern Indigenous communities, and First Book Canada, with its focus on reading and literacy for underserved, marginalized youth.

    For decades these Five Families ruled New York and built the American Mafia (or Cosa Nostra) into an underworld empire. Today, the Mafia is an endangered species, battered and beleaguered by aggressive investigators, incompetent leadership, betrayals and generational changes that produced violent and unreliable leaders and recruits. A twenty year assault against the five families in particular blossomed into the most successful law enforcement campaign of the last century. Five Families is the vivid story of the rise and fall of New York's premier dons from Lucky Luciano to Paul Castellano to John Gotti and more. The book also brings the reader right up to the possible resurgence of the Mafia as the FBI and local law enforcement agencies turn their attention to homeland security and away from organized crime.